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Volumn 346, Issue 7893, 2013, Pages

Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: Systematic review and meta-analysis of randomised controlled trials

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CYANOCOBALAMIN; FOLIC ACID; PYRIDOXINE; RETINOL; SELENIUM; VITAMIN; VITAMIN D;

EID: 84873344743     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.f10     Document Type: Article
Times cited : (383)

References (83)
  • 1
    • 79959918738 scopus 로고    scopus 로고
    • Total cardiovascular risk approach to improve efficiency of cardiovascular prevention in resource constrain settings
    • Mendis S, Lindholm LH, Anderson SG, Alwan A, Koju R, Onwubere BJ, et al. Total cardiovascular risk approach to improve efficiency of cardiovascular prevention in resource constrain settings. J Clin Epidemiol 2011;64:1451-62.
    • (2011) J Clin Epidemiol , vol.64 , pp. 1451-62
    • Mendis, S.1    Lindholm, L.H.2    Anderson, S.G.3    Alwan, A.4    Koju, R.5    Onwubere, B.J.6
  • 3
    • 13744262348 scopus 로고    scopus 로고
    • The global burden of disease attributable to low consumption of fruit and vegetables: Implications for the global strategy on diet
    • Lock K, Pomerleau J, Causer L, Altmann DR, McKee M. The global burden of disease attributable to low consumption of fruit and vegetables: implications for the global strategy on diet. Bull World Health Organ 2005;83:100-8. (Pubitemid 40239002)
    • (2005) Bulletin of the World Health Organization , vol.83 , Issue.2 , pp. 100-108
    • Lock, K.1    Pomerleau, J.2    Causer, L.3    Altmann, D.R.4    McKee, M.5
  • 4
    • 79959299900 scopus 로고    scopus 로고
    • Coronary heart disease prevention: Nutrients, foods, and dietary patterns
    • Bhupathiraju SN, Tucker KL. Coronary heart disease prevention: nutrients, foods, and dietary patterns. Clin Chim Acta 2011;412:1493-514.
    • (2011) Clin Chim Acta , vol.412 , pp. 1493-514
    • Bhupathiraju, S.N.1    Tucker, K.L.2
  • 5
    • 0037840165 scopus 로고    scopus 로고
    • Use of antioxidant vitamins for the prevention of cardiovascular disease: Meta-analysis of randomised trials
    • DOI 10.1016/S0140-6736(03)13637-9
    • Vivekananthan DP, Penn MS, Sapp SK, Hsu A, Topol EJ. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet 2003;361:2017-23. (Pubitemid 36695043)
    • (2003) Lancet , vol.361 , Issue.9374 , pp. 2017-2023
    • Vivekananthan, D.P.1    Penn, M.S.2    Sapp, S.K.3    Hsu, A.4    Topol, E.J.5
  • 7
    • 77953133802 scopus 로고    scopus 로고
    • Efficacy of homocysteine-lowering therapy with folic acid in stroke prevention: A meta-analysis
    • Lee M, Hong KS, Chang SC, Saver JL. Efficacy of homocysteine-lowering therapy with folic acid in stroke prevention: a meta-analysis. Stroke 2010;41:1205-12.
    • (2010) Stroke , vol.41 , pp. 1205-12
    • Lee, M.1    Hong, K.S.2    Chang, S.C.3    Saver, J.L.4
  • 8
    • 79953020963 scopus 로고    scopus 로고
    • Folic acid therapy and cardiovascular disease in esrd or advanced chronic kidney disease: A meta-analysis
    • Qin X, Huo Y, Langman CB, Hou F, Chen Y, Matossian D, et al. Folic acid therapy and cardiovascular disease in ESRD or advanced chronic kidney disease: a meta-analysis. Clin J Am Soc Nephrol 2011;6:482-8.
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 482-8
    • Qin, X.1    Huo, Y.2    Langman, C.B.3    Hou, F.4    Chen, Y.5    Matossian, D.6
  • 10
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • DOI 10.1002/sim.1186
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002;21:1539-58. (Pubitemid 34746062)
    • (2002) Statistics in Medicine , vol.21 , Issue.11 , pp. 1539-1558
    • Higgins, J.P.T.1    Thompson, S.G.2
  • 12
    • 0028724815 scopus 로고
    • Coenzyme q10 and antioxidants in acute myocardial infarction
    • Kuklinski B, Weissenbacher E, Fahnrich A. Coenzyme Q10 and antioxidants in acute myocardial infarction. Mol Aspects Med 1994;15suppl:s143-7.
    • (1994) Mol Aspects Med , vol.15 , Issue.SUPPL.
    • Kuklinski, B.1    Weissenbacher, E.2    Fahnrich, A.3
  • 13
    • 0028875815 scopus 로고
    • Vitamin e plus aspirin compared with aspirin alone in patients with transient ischemic attacks
    • Steiner M, Glantz M, Lekos A. Vitamin E plus aspirin compared with aspirin alone in patients with transient ischemic attacks. Am J Clin Nutr 1995;62:1381-4.S.
    • (1995) Am J Clin Nutr , vol.62
    • Steiner, M.1    Glantz, M.2    Lekos, A.3
  • 15
    • 0029925181 scopus 로고    scopus 로고
    • Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)
    • DOI 10.1016/S0140-6736(96)90866-1
    • Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 1996;347:781-6. (Pubitemid 26091640)
    • (1996) Lancet , vol.347 , Issue.9004 , pp. 781-786
    • Stephens, N.G.1    Parsons, A.2    Schofield, P.M.3    Kelly, F.4    Cheeseman, K.5    Mitchinson, M.J.6    Brown, M.J.7
  • 19
    • 0030916162 scopus 로고    scopus 로고
    • Randomised trial of α-tocopherol and β-carotene supplements on incidence of major coronary events in men with previous myocardial infarction
    • DOI 10.1016/S0140-6736(97)01234-8
    • Rapola JM, Virtamo J, Ripatti S, Huttenen JK, Albanes D, Taylor PR, et al. Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet 1997;349:1715-20. (Pubitemid 27252669)
    • (1997) Lancet , vol.349 , Issue.9067 , pp. 1715-1720
    • Rapola, J.M.1    Virtamo, J.2    Ripatti, S.3    Huttunen, J.K.4    Albanes, D.5    Taylor, P.R.6    Heinonen, O.P.7
  • 20
    • 0032559780 scopus 로고    scopus 로고
    • Effect of vitamin E and beta carotene on the incidence of primary nonfatal myocardial infarction and fatal coronary heart disease
    • DOI 10.1001/archinte.158.6.668
    • Virtamo J, Rapola JM, Ripatti S, Heinonen OP, Taylor PR, Albanes D, et al. Effect of vitamin E and beta carotene on the incidence of primary nonfatal myocardial infarction and fatal coronary heart disease. Arch Intern Med 1998;158:668-75. (Pubitemid 28144826)
    • (1998) Archives of Internal Medicine , vol.158 , Issue.6 , pp. 668-675
    • Virtamo, J.1    Rapola, J.M.2    Ripatti, S.3    Heinonen, O.P.4    Taylor, P.R.5    Albanes, D.6    Huttunen, J.K.7
  • 21
    • 0345109256 scopus 로고    scopus 로고
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin e after myocardial infarction: Results of the gissi-prevenzione trial
    • GISSI-Prevenzione Investigators (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico
    • GISSI-Prevenzione Investigators (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico). Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Lancet 1999;354:447-55.
    • (1999) Lancet , vol.354 , pp. 447-455
  • 23
    • 0033612873 scopus 로고    scopus 로고
    • Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: A randomised controlled trial
    • DOI 10.1016/S0140-6736(98)12168-2
    • Green A, Williams G, Neale R, Hart V, Leslie D, Parsons P, et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial. Lancet 1999;354:723-9. (Pubitemid 29405786)
    • (1999) Lancet , vol.354 , Issue.9180 , pp. 723-729
    • Green, A.1    Williams, G.2    Neale, R.3    Hart, V.4    Leslie, D.5    Parsons, P.6    Marks, G.C.7    Gaffney, P.8    Battistutta, D.9    Frost, C.10    Lang, C.11    Russell, A.12
  • 24
    • 0034688195 scopus 로고    scopus 로고
    • Vitamin E supplementation and cardiovascular events in high-risk patients
    • DOI 10.1056/NEJM200001203420302
    • Yusuf S, Dagenais G, Pogue J, Bosch J, Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000;342:154-60. (Pubitemid 30051646)
    • (2000) New England Journal of Medicine , vol.342 , Issue.3 , pp. 154-160
    • Yusuf, S.1
  • 25
    • 0034619027 scopus 로고    scopus 로고
    • Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (space): Randomised placebo-controlled trial
    • Boaz M, Smetana S, Weinstein T, Matas Z, Gafter U, Iaina A, et al. Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial. Lancet 2000;356:1213-8.
    • (2000) Lancet , vol.356 , pp. 1213-8
    • Boaz, M.1    Smetana, S.2    Weinstein, T.3    Matas, Z.4    Gafter, U.5    Iaina, A.6
  • 27
    • 0035852471 scopus 로고    scopus 로고
    • Low-dose aspirin and vitamin e in people at cardiovascular risk: A randomised trial in general practice
    • Collaborative Group of the Primary Prevention Project
    • De Gaetano G; Collaborative Group of the Primary Prevention Project. Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general practice. Lancet 2001;357:89-95.
    • (2001) Lancet , vol.357 , pp. 89-95
    • De Gaetano, G.1
  • 30
    • 0037031094 scopus 로고    scopus 로고
    • Mrc/bhf heart protection study of antioxidant vitamin supplementation in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002;360:23-33.
    • (2002) Lancet , vol.360 , pp. 23-33
  • 31
    • 0037190083 scopus 로고    scopus 로고
    • 6 on clinical outcome after percutaneous coronary intervention: The Swiss heart study: A randomized controlled trial
    • Schnyder G, Roffi M, Flammer Y, Pin R, Hess OM. Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention: the Swiss Heart study: a randomised controlled trial. JAMA 2002;288:973-9. (Pubitemid 34920462)
    • (2002) Journal of the American Medical Association , vol.288 , Issue.8 , pp. 973-979
    • Schnyder, G.1    Roffi, M.2    Flammer, Y.3    Pin, R.4    Hess, O.M.5
  • 35
    • 0037374270 scopus 로고    scopus 로고
    • Effect of four monthly oral vitamin d3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: Randomised double blind controlled trial
    • Trivedi DP, Doll R, Khaw KT. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. BMJ 2003;326:469.
    • (2003) BMJ , vol.326 , pp. 469
    • Trivedi, D.P.1    Doll, R.2    Khaw, K.T.3
  • 40
    • 33644544396 scopus 로고    scopus 로고
    • Clinical and laboratory safety of one year's use of a combination calcium + vitamin D tablet in ambulatory elderly women with vitamin D insufficiency: Results of a multicenter, randomized, double-blind, placebo-controlled study
    • DOI 10.1016/j.clinthera.2005.12.010, PII S014929180500322X
    • Brazier M, Grados F, Kamel S, Mathieu M, Morel A, Maamer M, et al. Clinical and laboratory safety of one year's use of a combination calcium + vitamin D tablet in ambulatory elderly women with vitamin D insufficiency: results of a multicenter, randomised, double-blind, placebo-controlled study. Clin Ther 2005;27:1885-93. (Pubitemid 43293210)
    • (2005) Clinical Therapeutics , vol.27 , Issue.12 , pp. 1885-1893
    • Brazier, M.1    Grados, F.2    Kamel, S.3    Mathieu, M.4    Morel, A.5    Maamer, M.6    Sebert, J.-L.7    Fardellone, P.8
  • 42
    • 33644908006 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in the atherosclerosis and folic acid supplementation trial (asfast) in chronic renal failure: A multicenter, randomised, controlled trial
    • Zoungas S, McGrath BP, Branley P, Kerr PG, Muske C, Wolfe R, et al. Cardiovascular morbidity and mortality in the atherosclerosis and folic acid supplementation trial (ASFAST) in chronic renal failure: a multicenter, randomised, controlled trial. J Am Coll Cardiol 2006;47:1108-16.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 1108-16
    • Zoungas, S.1    McGrath, B.P.2    Branley, P.3    Kerr, P.G.4    Muske, C.5    Wolfe, R.6
  • 43
    • 33645753544 scopus 로고    scopus 로고
    • Homocysteine lowering with folic acid and b vitamins in vascular disease
    • Lonn E, Yusuf S, Arnold MJ, Sheridan P, Pogue J, Micks M, et al. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med 2006;354:1567-77.
    • (2006) N Engl J Med , vol.354 , pp. 1567-77
    • Lonn, E.1    Yusuf, S.2    Arnold, M.J.3    Sheridan, P.4    Pogue, J.5    Micks, M.6
  • 45
    • 33645723875 scopus 로고    scopus 로고
    • Effects of selenium supplementation on cardiovascular disease incidence and mortality: Secondary analyses in a randomised clinical trial
    • Stranges S, Marshall JR, Trevisan M, Natarajan R, Donahue RP, Combs GF, et al. Effects of selenium supplementation on cardiovascular disease incidence and mortality: secondary analyses in a randomised clinical trial. Am J Epidemiol 2006;163:694-9.
    • (2006) Am J Epidemiol , vol.163 , pp. 694-9
    • Stranges, S.1    Marshall, J.R.2    Trevisan, M.3    Natarajan, R.4    Donahue, R.P.5    Combs, G.F.6
  • 46
    • 34548566329 scopus 로고    scopus 로고
    • Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: A randomized controlled trial
    • DOI 10.1001/jama.298.10.1163
    • Jamison RL, Hartigan P, Kaufman JS, Goldfarb DS, Warren SR, Guarino PD, et al. Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomised controlled trial. JAMA 2007;298:1163-70. (Pubitemid 47403102)
    • (2007) Journal of the American Medical Association , vol.298 , Issue.10 , pp. 1163-1170
    • Jamison, R.L.1    Hartigan, P.2    Kaufman, J.S.3    Goldfarb, D.S.4    Warren, S.R.5    Guarino, P.D.6    Gaziano, J.M.7
  • 48
    • 43249119722 scopus 로고    scopus 로고
    • Evaluation of a fall-prevention program in older people after femoral neck fracture: A one-year follow-up
    • Berggren M, Stenvall M, Olofsson B, Gustafson Y. Evaluation of a fall-prevention program in older people after femoral neck fracture: a one-year follow-up. Osteoporos Int 2008;19:801-9.
    • (2008) Osteoporos Int , vol.19 , pp. 801-9
    • Berggren, M.1    Stenvall, M.2    Olofsson, B.3    Gustafson, Y.4
  • 50
    • 38349019697 scopus 로고    scopus 로고
    • Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women
    • Prince RL, Austin N, Devine A, Dick IM, Bruce D, Zhu K. Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women. Arch Intern Med 2008;168:103-8.
    • (2008) Arch Intern Med , vol.168 , pp. 103-8
    • Prince, R.L.1    Austin, N.2    Devine, A.3    Dick, I.M.4    Bruce, D.5    Zhu, K.6
  • 52
    • 49949101867 scopus 로고    scopus 로고
    • Mortality and cardiovascular events in patients treated with homocysteine-lowering b vitamins after coronary angiography: A randomised controlled trial
    • Ebbing M, Bleie Ø, Ueland PM, Nordrehaug JE, Nilsen DW, Vollset SE, et al. Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: a randomised controlled trial. JAMA 2008;300:795-804.
    • (2008) JAMA , vol.300 , pp. 795-804
    • Ebbing, M.1    Bleie, O.2    Ueland, P.M.3    Nordrehaug, J.E.4    Nilsen, D.W.5    Vollset, S.E.6
  • 53
    • 62449195299 scopus 로고    scopus 로고
    • High-dose b vitamin supplementation and progression of subclinical atherosclerosis: A randomised controlled trial
    • Hodis HN, Mack WJ, Dustin L, Mahrer PR, Azen SP, Detrano R, et al. High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomised controlled trial. Stroke 2009;40:730-6.
    • (2009) Stroke , vol.40 , pp. 730-6
    • Hodis, H.N.1    Mack, W.J.2    Dustin, L.3    Mahrer, P.R.4    Azen, S.P.5    Detrano, R.6
  • 54
    • 77951645401 scopus 로고    scopus 로고
    • Effect of b-vitamin therapy on progression of diabetic nephropathy: A randomised controlled trial
    • House AA, Eliasziw M, Cattran DC, Churchill DN, Oliver MJ, Fine A, et al. Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomised controlled trial. JAMA 2010;303:1603-9.
    • (2010) JAMA , vol.303 , pp. 1603-9
    • House, A.A.1    Eliasziw, M.2    Cattran, D.C.3    Churchill, D.N.4    Oliver, M.J.5    Fine, A.6
  • 55
    • 77950246384 scopus 로고    scopus 로고
    • B vitamins and the risk of total mortality and cardiovascular disease in end-stage renal disease: Results of a randomised controlled trial
    • Heinz J, Kropf S, Domröse U, Westphal S, Borucki K, Luley C, et al. B vitamins and the risk of total mortality and cardiovascular disease in end-stage renal disease: results of a randomised controlled trial. Circulation 2010;121:1432-8.
    • (2010) Circulation , vol.121 , pp. 1432-8
    • Heinz, J.1    Kropf, S.2    Domröse, U.3    Westphal, S.4    Borucki, K.5    Luley, C.6
  • 56
    • 77953867844 scopus 로고    scopus 로고
    • Effects of homocysteine-lowering with folic acid plus vitamin b12 vs placebo on mortality and major morbidity in myocardial infarction survivors: A randomised trial
    • Armitage JM, Bowman L, Clarke RJ, Wallendszus K, Bulbulia R, Rahimi K, et al. Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomised trial. JAMA 2010;303:2486-94.
    • (2010) JAMA , vol.303 , pp. 2486-94
    • Armitage, J.M.1    Bowman, L.2    Clarke, R.J.3    Wallendszus, K.4    Bulbulia, R.5    Rahimi, K.6
  • 57
    • 79551499975 scopus 로고    scopus 로고
    • Effects of b vitamins and omega 3 fatty acids on cardiovascular diseases: A randomised placebo controlled trial
    • Galan P, Kesse-Guyot E, Czernichow S, Briancon S, Blacher J, Hercberg S. Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial. BMJ 2010;341:c6273.
    • (2010) BMJ , vol.341
    • Galan, P.1    Kesse-Guyot, E.2    Czernichow, S.3    Briancon, S.4    Blacher, J.5    Hercberg, S.6
  • 58
    • 77955656519 scopus 로고    scopus 로고
    • B vitamins in patients with recent transient ischaemic attack or stroke in the vitamins to prevent stroke (vitatops) trial: A randomised, double-blind, parallel, placebo-controlled trial
    • VITATOPS Trial Study Group
    • VITATOPS Trial Study Group. B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial. Lancet Neurol 2010;9:855-65.
    • (2010) Lancet Neurol , vol.9 , pp. 855-65
  • 59
    • 79955565728 scopus 로고    scopus 로고
    • Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: Primary results from the folic acid for vascular outcome reduction in transplantation trial
    • Bostom AG, Carpenter MA, Kusek JW, Levey AS, Hunsicker L, Pfeffer MA, et al. Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the folic acid for vascular outcome reduction in transplantation trial. Circulation 2011;123:1763-70.
    • (2011) Circulation , vol.123 , pp. 1763-70
    • Bostom, A.G.1    Carpenter, M.A.2    Kusek, J.W.3    Levey, A.S.4    Hunsicker, L.5    Pfeffer, M.A.6
  • 60
    • 84868307162 scopus 로고    scopus 로고
    • Multivitamins in the prevention of cardiovascular disease in men: The physicians' health study ii randomised controlled trial
    • Sesso HD, Christen WG, Bubes V, Smith JP, MacFadyen J, Schavartz M, et al. Multivitamins in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomised controlled trial. JAMA 2012;308:1751-60.
    • (2012) JAMA , vol.308 , pp. 1751-60
    • Sesso, H.D.1    Christen, W.G.2    Bubes, V.3    Smith, J.P.4    MacFadyen, J.5    Schavartz, M.6
  • 61
    • 77957949167 scopus 로고    scopus 로고
    • Effects of lowering homocysteine levels with b vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomised trials involving 37 485 individuals
    • Clarke R, Halsey J, Lewington S, Lonn E, Armitage J, Manson JE, et al. Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: meta-analysis of 8 randomised trials involving 37 485 individuals. Arch Intern Med 2010;170:1622-31.
    • (2010) Arch Intern Med , vol.170 , pp. 1622-31
    • Clarke, R.1    Halsey, J.2    Lewington, S.3    Lonn, E.4    Armitage, J.5    Manson, J.E.6
  • 62
    • 72449161167 scopus 로고    scopus 로고
    • Effect of homocysteine interventions on the risk of cardiocerebrovascular events: A meta-analysis of randomised controlled trials
    • Mei W, Rong Y, Jinming L, Yongjun L, Hui Z. Effect of homocysteine interventions on the risk of cardiocerebrovascular events: a meta-analysis of randomised controlled trials. Int J Clin Pract 2010;64:208-15.
    • (2010) Int J Clin Pract , vol.64 , pp. 208-15
    • Mei, W.1    Rong, Y.2    Jinming, L.3    Yongjun, L.4    Hui, Z.5
  • 64
    • 3242731658 scopus 로고    scopus 로고
    • Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease
    • DOI 10.1001/archinte.164.14.1552
    • Eidelman RS, Hollar D, Hebert PR, Lamas GA, Hennekens CH. Randomised trials of vitamin E in the treatment and prevention of cardiovascular disease. Arch Intern Med 2004;164:1552-6. (Pubitemid 38970477)
    • (2004) Archives of Internal Medicine , vol.164 , Issue.14 , pp. 1552-1556
    • Eidelman, R.S.1    Hollar, D.2    Hebert, P.R.3    Lamas, G.A.4    Hennekens, C.H.5
  • 66
    • 80053251718 scopus 로고    scopus 로고
    • Effect of folic acid supplementation on cardiovascular outcomes: A systematic review and meta-analysis
    • Zhou YH, Tang JY, Wu MJ, Lu J, Wei X, Qin YY, et al. Effect of folic acid supplementation on cardiovascular outcomes: a systematic review and meta-analysis. PLoS One 2011;6:e25142.
    • (2011) PLoS One , vol.6
    • Zhou, Y.H.1    Tang, J.Y.2    Wu, M.J.3    Lu, J.4    Wei, X.5    Qin, Y.Y.6
  • 67
    • 0028945579 scopus 로고
    • Relation of vascular oxidative stress, alpha-tocopherol, and hypercholesterolemia to early atherosclerosis in hamsters
    • Parker RA, Sabrah T, Cap M, Gill BT. Relation of vascular oxidative stress, alpha-tocopherol, and hypercholesterolemia to early atherosclerosis in hamsters. Arterioscler Thromb Vasc Biol 1995;15:349-58.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 349-58
    • Parker, R.A.1    Sabrah, T.2    Cap, M.3    Gill, B.T.4
  • 68
    • 0031752607 scopus 로고    scopus 로고
    • Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice
    • DOI 10.1038/2685
    • Pratico D, Tangirala RK, Rader DJ, Rokach J, FitzGerald GA. Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice. Nat Med 1998;4:1189-92. (Pubitemid 28468835)
    • (1998) Nature Medicine , vol.4 , Issue.10 , pp. 1189-1192
    • Pratico, D.1    Tangirala, R.K.2    Rader, D.J.3    Rokach, J.4    Fitzgerald, G.A.5
  • 71
    • 0034604279 scopus 로고    scopus 로고
    • Vitamin E reduces the uptake of oxidized LDL by inhibiting CD36 scavenger receptor expression in cultured aortic smooth muscle cells
    • Ricciarelli R, Zingg JM, Azzi A. Vitamin E reduces the uptake of oxidized LDL by inhibiting CD36 scavenger receptor expression in cultured aortic smooth muscle cells. Circulation 2000;102:82-7. (Pubitemid 30430557)
    • (2000) Circulation , vol.102 , Issue.1 , pp. 82-87
    • Ricciarelli, R.1    Zingg, J.-M.2    Azzi, A.3
  • 72
    • 0036932221 scopus 로고    scopus 로고
    • Vitamin C and vitamin E antagonistically modulate human vascular endothelial and smooth muscle cell DNA synthesis and proliferation
    • DOI 10.1007/s003940200003
    • Ulrich-Merzenich G, Metzner C, Schiermeyer B, Vetter H. Vitamin C and vitamin E antagonistically modulate human vascular endothelial and smooth muscle cell DNA synthesis and proliferation. Eur J Nutr 2002;41:27-34. (Pubitemid 36061217)
    • (2002) European Journal of Nutrition , vol.41 , Issue.1 , pp. 27-34
    • Ulrich-Merzenich, G.1    Metzner, C.2    Schiermeyer, B.3    Vetter, H.4
  • 73
    • 78649465557 scopus 로고    scopus 로고
    • Antioxidant vitamins and their use in preventing cardiovascular disease
    • Farbstein D, Kozak-Blickstein A, Levy AP. Antioxidant vitamins and their use in preventing cardiovascular disease. Molecules 2010;15:8098-110.
    • (2010) Molecules , vol.15 , pp. 8098-110
    • Farbstein, D.1    Kozak-Blickstein, A.2    Levy, A.P.3
  • 75
    • 0019812319 scopus 로고
    • Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: Recognition by receptors for acetylated low density lipoproteins
    • Henriksen T, Mahoney EM, Steinberg D. Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins. Proc Natl Acad Sci U S A 1981;78:6499-503. (Pubitemid 12179740)
    • (1981) Proceedings of the National Academy of Sciences of the United States of America , vol.78 , Issue.10 , pp. 6499-6503
    • Henriksen, T.1    Mahoney, E.M.2    Steinberg, D.3
  • 77
    • 46249124511 scopus 로고    scopus 로고
    • Inflammation in the vascular bed: Importance of vitamin c
    • Aguirre R, May JM. Inflammation in the vascular bed: importance of vitamin C. Pharmacol Ther 2008;119:96-103.
    • (2008) Pharmacol Ther , vol.119 , pp. 96-103
    • Aguirre, R.1    May, J.M.2
  • 78
    • 33847378451 scopus 로고    scopus 로고
    • Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis
    • DOI 10.1001/jama.297.8.842
    • Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomised trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 2007;297:842-57. (Pubitemid 46333949)
    • (2007) Journal of the American Medical Association , vol.297 , Issue.8 , pp. 842-857
    • Bjelakovic, G.1    Nikolova, D.2    Gluud, L.L.3    Simonetti, R.G.4    Gluud, C.5
  • 79
    • 84861927005 scopus 로고    scopus 로고
    • Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
    • Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases. Cochrane Database Syst Rev 2012;3:CD007176.
    • (2012) Cochrane Database Syst Rev , vol.3
    • Bjelakovic, G.1    Nikolova, D.2    Gluud, L.L.3    Simonetti, R.G.4    Gluud, C.5
  • 80
    • 77949317645 scopus 로고    scopus 로고
    • Effects of antioxidant supplements on cancer prevention: Meta-analysis of randomised controlled trials
    • Myung SK, Kim Y, Ju W, Choi HJ, Bae WK. Effects of antioxidant supplements on cancer prevention: meta-analysis of randomised controlled trials. Ann Oncol 2010;21:166-79.
    • (2010) Ann Oncol , vol.21 , pp. 166-79
    • Myung, S.K.1    Kim, Y.2    Ju, W.3    Choi, H.J.4    Bae, W.K.5
  • 82
    • 70350529010 scopus 로고    scopus 로고
    • Risk of bias versus quality assessment of randomised controlled trials: Cross sectional study
    • Hartling L, Ospina M, Liang Y, Dryden DM, Hooton N, Krebs Seida J, et al. Risk of bias versus quality assessment of randomised controlled trials: cross sectional study. BMJ 2009;339:b4012.
    • (2009) BMJ , vol.339
    • Hartling, L.1    Ospina, M.2    Liang, Y.3    Dryden, D.M.4    Hooton, N.5    Krebs Seida, J.6
  • 83
    • 56149111693 scopus 로고    scopus 로고
    • Vitamins e and c in the prevention of cardiovascular disease in men: The physicians' health study ii randomised controlled trial
    • Sesso HD, Buring JE, Christen WG, Kurth T, Belanger C, MacFadyen J, et al. Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomised controlled trial. JAMA 2008;300:2123-33.
    • (2008) JAMA , vol.300 , pp. 2123-33
    • Sesso, H.D.1    Buring, J.E.2    Christen, W.G.3    Kurth, T.4    Belanger, C.5    MacFadyen, J.6


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