Induction of G2/M phase arrest and apoptosis by the flavonoid tamarixetin on human leukemia cells

Molecular Carcinogenesis

Volumn 53, Issue 12, 2014, Pages 939-950

  Nicolini, Fabio ^a,b   Burmistrova, Olga ^a   Marrero, María Teresa ^a   Torres, Fernando ^a,b   Hernández, Cristina ^a,b   Quintana, José ^a,b   Estévez, Francisco ^a,b  

^a UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^b Madrid Spain   (Spain)

Author keywords

Apoptosis; Cell cycle arrest; Flavonoids

Indexed keywords

ACETYLCYSTEINE; BUB1 RELATED PROTEIN; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; COLCHICINE; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 25C; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYTOCHROME C; FLAVONOID; MULTIDRUG RESISTANCE PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; PROTEIN TYROSINE PHOSPHATASE; TAMARIXETIN; UNCLASSIFIED DRUG; BUB1 PROTEIN, HUMAN; CDC25C PROTEIN, HUMAN; CDK1 PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DISACCHARIDE; PROTEIN BCL 2; PROTEIN SERINE THREONINE KINASE; QUERCETIN; TUBULIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOACCUMULATION; CELL CYCLE PROGRESSION; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MICROTUBULE ASSEMBLY; MTT ASSAY; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; DRUG EFFECTS; K562 CELL LINE; LEUKEMIA; METABOLISM; TUMOR CELL LINE;

APOPTOSIS; CDC25 PHOSPHATASES; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CYCLIN B1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; DISACCHARIDES; FLAVONOIDS; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; K562 CELLS; LEUKEMIA; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; QUERCETIN; TUBULIN;

EID: 84911420590     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22055     Document Type: Article

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