Maternal immune activation alters behavior in adult offspring, with subtle changes in the cortical transcriptome and epigenome

Schizophrenia Research

Volumn 140, Issue 1-3, 2012, Pages 175-184

  Connor, Caroline M ^a   Dincer, Aslihan ^a   Straubhaar, Juerg ^b   Galler, Janina R ^c   Houston, Isaac B ^a   Akbarian, Schahram ^a  

^a Brudnick Neuropsychiatric Research Institute   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Chromatin; Epigenetic; Epigenome; Maternal immune activation; Nucleosome; Psychosis; Transcription start site; Transcriptome

Indexed keywords

DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; HISTONE H3; INTERLEUKIN 6; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; RNA; TRANSCRIPTOME;

AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BRAIN CORTEX; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOKINE RESPONSE; DISRUPTED IN SCHIZOPHRENIA 1 GENE; EMBRYO; EPIGENETICS; FEMALE; FETUS; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE LOCATION; GENE MAPPING; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC MARKER; GENETIC RISK; HISTONE METHYLATION; HUMAN; IMMUNOSTIMULATION; MEMORY DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGENY; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTOMICS; WORKING MEMORY;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; CHROMATIN IMMUNOPRECIPITATION; CYTOKINES; EMBRYO, MAMMALIAN; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPIGENOMICS; FEMALE; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; INTERFERON INDUCERS; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICROARRAY ANALYSIS; NEURONS; POLY I-C; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTOME;

EID: 84865313397     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2012.06.037     Document Type: Article

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