GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD 67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss

Molecular Psychiatry

Volumn 10, Issue 6, 2005, Pages 581-588

  Addington, A M ^a   Gornick, M ^a   Duckworth, J ^b   Sporn, A ^a   Gogtay, N ^a   Bobb, A ^a   Greenstein, D ^a   Lenane, M ^a   Gochman, P ^a   Baker, N ^a   Balkissoon, R ^a   Vakkalanka, R K ^a   Weinberger, D R ^a   Rapoport, J L ^a   Straub, R E ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Brain development; Candidate gene; Child psychosis; GAD1; Linkage disequilibrium; Quantitative transmission disequilibrium test; Transmission disequilibrium test

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 65; MESSENGER RNA;

5' UNTRANSLATED REGION; ADOLESCENT; ARTICLE; AUTOPSY; BRAIN DYSFUNCTION; BRAIN SIZE; CHROMOSOME 2Q; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GABAERGIC SYSTEM; GENE EXPRESSION; GENETIC ASSOCIATION; GRAY MATTER; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PHENOTYPE; PREFRONTAL CORTEX; PRIORITY JOURNAL; QUANTITATIVE TRAIT; RISK FACTOR; SCHIZOPHRENIA; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM;

5' FLANKING REGION; ADOLESCENT; ADULT; AGE OF ONSET; CEREBRAL CORTEX; CHILD; CHROMOSOMES, HUMAN, PAIR 2; FAMILY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUTAMATE DECARBOXYLASE; HAPLOTYPES; HUMANS; ISOENZYMES; LINKAGE (GENETICS); MALE; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; SCHIZOPHRENIA;

EID: 21244501298     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001599     Document Type: Article

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