-
1
-
-
12344254627
-
Phenotype of schizophrenia: A review and formulation
-
DOI 10.1038/sj.mp.4001563
-
Tamminga CA, Holcomb HH. 2004. Phenotype of schizophrenia: a review and formulation. Mol. Psychiatry 10:27-39 (Pubitemid 40139587)
-
(2005)
Molecular Psychiatry
, vol.10
, Issue.1
, pp. 27-39
-
-
Tamminga, C.A.1
Holcomb, H.H.2
-
4
-
-
0030962428
-
Nefazodone. A review of its pharmacology and clinical efficacy in the management of major depression
-
Davis R, Whittington R, Bryson HM. 1997. Nefazodone: a review of its pharmacology and clinical efficacy in the management of major depression. Drugs 53:608-36 (Pubitemid 27145956)
-
(1997)
Drugs
, vol.53
, Issue.4
, pp. 608-636
-
-
Davis, R.1
Whittington, R.2
Bryson, H.M.3
-
5
-
-
38349057998
-
The burden of schizophrenia on caregivers: A review
-
Awad AG, Voruganti LN. 2008. The burden of schizophrenia on caregivers: a review. Pharmacoeconomics 26:149-62
-
(2008)
Pharmacoeconomics
, vol.26
, pp. 149-62
-
-
Awad, A.G.1
Voruganti, L.N.2
-
6
-
-
34547650520
-
The neuropharmacology of psychosis
-
DOI 10.1093/schbul/sbm063
-
Tamminga CA, Davis JM. 2007. The neuropharmacology of psychosis. Schizophr. Bull. 33:937-46 (Pubitemid 47216663)
-
(2007)
Schizophrenia Bulletin
, vol.33
, Issue.4
, pp. 937-946
-
-
Tamminga, C.A.1
Davis, J.M.2
-
7
-
-
0005689106
-
Review of antipsychotic drug literature
-
ed. DF Klein, JM Davis Baltimore, MD: The Williams and Wilkins Company
-
Davis JM. 1969. Review of antipsychotic drug literature. In Diagnosis and Drug Treatment of Psychiatric Disorders, ed. DF Klein, JM Davis, pp. 52-138. Baltimore, MD: The Williams and Wilkins Company
-
(1969)
Diagnosis and Drug Treatment of Psychiatric Disorders
, pp. 52-138
-
-
Davis, J.M.1
-
8
-
-
0037449586
-
Medicine: What are the right targets for psychopharmacology?
-
DOI 10.1126/science.1077141
-
Hyman SE, Fenton WS. 2003. Medicine: What are the right targets for psychopharmacology? Science 299:350-51 (Pubitemid 36120025)
-
(2003)
Science
, vol.299
, Issue.5605
, pp. 350-351
-
-
Hyman, S.E.1
Fenton, W.S.2
-
9
-
-
0142244688
-
Schizophrenia
-
DOI 10.1056/NEJMra035458
-
Freedman R. 2003. Schizophrenia. N. Engl. J. Med. 349:1738-49 (Pubitemid 37315012)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.18
, pp. 1738-1749
-
-
Freedman, R.1
-
10
-
-
0033521616
-
Efficacy and extrapyramidal side-effects of the new antipsychotics olanzapine, quetiapine, risperidone, and sertindole compared to conventional antipsychotics and placebo. A meta-analysis of randomized controlled trials
-
DOI 10.1016/S0920-9964(98)00105-4, PII S0920996498001054
-
Leucht S, Pitschel-Walz G, Abraham D, Kissling W. 1999. Efficacy and extrapyramidal side-effects of the new antipsychotics olanzapine, quetiapine, risperidone, and sertindole compared to conventional antipsychotics and placebo. A meta-analysis of randomized controlled trials. Schizophr. Res. 35:51-68 (Pubitemid 29023554)
-
(1999)
Schizophrenia Research
, vol.35
, Issue.1
, pp. 51-68
-
-
Leucht, S.1
Pitschel-Walz, G.2
Abraham, D.3
Kissling, W.4
-
11
-
-
70449641202
-
Second-generation antipsychotics for schizophrenia: Can we resolve the conflict?
-
Leucht S, Kissling W, Davis JM. 2009. Second-generation antipsychotics for schizophrenia: Can we resolve the conflict? Psychol. Med. 39:1591-602
-
(2009)
Psychol. Med.
, vol.39
, pp. 1591-602
-
-
Leucht, S.1
Kissling, W.2
Davis, J.M.3
-
12
-
-
0038582771
-
New generation antipsychotics versus low-potency conventional antipsychotics: A systematic review and meta-analysis
-
DOI 10.1016/S0140-6736(03)13306-5
-
Leucht S, Wahlbeck K, Hamann J, Kissling W. 2003. New generation antipsychotics versus low-potency conventional antipsychotics: a systematic review and meta-analysis. Lancet 361:1581-89; comment 362:404, author reply 404-5 (Pubitemid 36578993)
-
(2003)
Lancet
, vol.361
, Issue.9369
, pp. 1581-1589
-
-
Leucht, S.1
Wahlbeck, K.2
Hamann, J.3
Kissling, W.4
-
13
-
-
33646160988
-
The NIMH-MATRICS project for developing cognition-enhancing agents for schizophrenia
-
Marder SR. 2006. The NIMH-MATRICS project for developing cognition-enhancing agents for schizophrenia. Dialogues Clin. Neurosci. 8:109-13
-
(2006)
Dialogues Clin. Neurosci.
, vol.8
, pp. 109-13
-
-
Marder, S.R.1
-
14
-
-
3142680754
-
MATRICS: Measurement and Treatment Research to Improve Cognition in Schizophrenia
-
Geyer MA, Tamminga C. 2004. MATRICS: Measurement and Treatment Research to Improve Cognition in Schizophrenia. Psychopharmacology 174:1-162
-
(2004)
Psychopharmacology
, vol.174
, pp. 1-162
-
-
Geyer, M.A.1
Tamminga, C.2
-
15
-
-
26444590039
-
Social cognition in schizophrenia: Recommendations from the Measurement and Treatment Research to Improve Cognition in Schizophrenia New Approaches Conference
-
DOI 10.1093/schbul/sbi049
-
Green MF, Olivier B, Crawley JN, Penn DL, Silverstein S. 2005. Social cognition in schizophrenia: recommendations from the Measurement and Treatment Research to Improve Cognition in Schizophrenia New Approaches Conference. Schizophr. Bull. 31:882-887 (Pubitemid 41437782)
-
(2005)
Schizophrenia Bulletin
, vol.31
, Issue.4
, pp. 882-887
-
-
Green, M.F.1
Olivier, B.2
Crawley, J.N.3
Penn, D.L.4
Silverstein, S.5
-
18
-
-
12344297022
-
Development in somatic treatments: Introduction
-
Tamminga CA. 1994. Development in somatic treatments: introduction. Am. J. Psychiatry 151:216-19
-
(1994)
Am. J. Psychiatry
, vol.151
, pp. 216-19
-
-
Tamminga, C.A.1
-
21
-
-
0031819008
-
Symptoms, cognitive functioning, and adaptive skills in geriatric patients with lifelong schizophrenia: A comparison across treatment sites
-
Harvey PD, Howanitz E, Parrella M, White L, Davidson M, et al. 1998. Symptoms, cognitive functioning, and adaptive skills in geriatric patients with lifelong schizophrenia: a comparison across treatment sites. Am. J. Psychiatry 155:1080-86 (Pubitemid 28357734)
-
(1998)
American Journal of Psychiatry
, vol.155
, Issue.8
, pp. 1080-1086
-
-
Harvey, P.D.1
Howanitz, E.2
Parrella, M.3
White, L.4
Davidson, M.5
Mohs, R.C.6
Hoblyn, J.7
Davis, K.L.8
-
22
-
-
0025978419
-
National Institute of Mental Health longitudinal study of chronic schizophrenia: Prognosis and predictors of outcome
-
Breier A, Schreiber JL, Dyer J, Pickar D. 1991. National Institute of Mental Health longitudinal study of chronic schizophrenia: prognosis and predictors of outcome. Arch. Gen. Psychiatry 48:239-46
-
(1991)
Arch. Gen. Psychiatry
, vol.48
, pp. 239-46
-
-
Breier, A.1
Schreiber, J.L.2
Dyer, J.3
Pickar, D.4
-
23
-
-
0031715299
-
Two-year outcome in first-episode schizophrenia: Predictive value of symptoms for quality of life
-
Ho BC, Nopoulos P, Flaum M, Arndt S, Andreasen NC. 1998. Two-year outcome in first-episode schizophrenia: predictive value of symptoms for quality of life. Am. J. Psychiatry 155:1196-201 (Pubitemid 28402512)
-
(1998)
American Journal of Psychiatry
, vol.155
, Issue.9
, pp. 1196-1201
-
-
Ho, B.-C.1
Nopoulos, P.2
Flaum, M.3
Arndt, S.4
Andreasen, N.C.5
-
24
-
-
1642316827
-
Review of cognition and brain structure in schizophrenia: Profiles, longitudinal course, and effects of treatment
-
DOI 10.1016/S0193-953X(03)00105-9, PII S0193953X03001059
-
Flashman LA, Green MF. 2004. Review of cognition and brain structure in schizophrenia: profiles, longitudinal course, and effects of treatment. Psychiatr. Clin. North Am. 27:1-18, vii (Pubitemid 38367767)
-
(2004)
Psychiatric Clinics of North America
, vol.27
, Issue.1
, pp. 1-18
-
-
Flashman, L.A.1
Green, M.F.2
-
25
-
-
0022323868
-
Global attentional deviance as a marker of risk for schizophrenia: Specificity and predictive validity
-
DOI 10.1037/0021-843X.94.4.470
-
Cornblatt BA, Erlenmeyer-Kimling L. 1985. Global attentional deviance as a marker of risk for schizophrenia: specificity and predictive validity. J. Abnorm. Psychol. 94:470-86 (Pubitemid 16159635)
-
(1985)
Journal of Abnormal Psychology
, vol.94
, Issue.4
, pp. 470-486
-
-
Cornblatt, B.A.1
Erlenmeyer-Kimling, L.2
-
26
-
-
0025949718
-
Neuropsycho-logical deficits in the early course of first episode schizophrenia
-
Bilder RM, Lipschutz-Broch L, Reiter G, Geisler S, Mayerhoff D, Lieberman JA. 1991. Neuropsycho-logical deficits in the early course of first episode schizophrenia. Schizophr. Res. 5:198-99
-
(1991)
Schizophr. Res.
, vol.5
, pp. 198-99
-
-
Bilder, R.M.1
Lipschutz-Broch, L.2
Reiter, G.3
Geisler, S.4
Mayerhoff, D.5
Lieberman, J.A.6
-
27
-
-
0032882848
-
Reduced gray matter volume in schizophrenia
-
DOI 10.1001/archpsyc.56.10.905
-
Gur RE, Turetsky BI, Bilker WB, Gur RC. 1999. Reduced gray matter volume in schizophrenia. Arch. Gen. Psychiatry 56:905-11 (Pubitemid 29480126)
-
(1999)
Archives of General Psychiatry
, vol.56
, Issue.10
, pp. 905-911
-
-
Gur, R.E.1
Turetsky, B.I.2
Bilker, W.B.3
Gur, R.C.4
-
28
-
-
0031763361
-
Subcortical MRI volumes in neuroleptic-naive and treated patients with schizophrenia
-
Gur RE, Maany V, Mozley PD, Swanson C, Bilker W, Gur RC. 1998. Subcortical MRI volumes in neuroleptic-naive and treated patients with schizophrenia. Am. J. Psychiatry 155:1711-17 (Pubitemid 28547495)
-
(1998)
American Journal of Psychiatry
, vol.155
, Issue.12
, pp. 1711-1717
-
-
Gur, R.E.1
Maany, V.2
Mozley, P.D.3
Swanson, C.4
Bilker, W.5
Gur, R.C.6
-
29
-
-
1942440875
-
Impairment of verbal memory and learning in antipsychotic-naive patients with first-episode schizophrenia
-
DOI 10.1016/S0920-9964(03)00125-7, PII S0920996403001257
-
Hill SK, Beers SR, Kmiec JA, Keshavan MS, Sweeney JA. 2004. Impairment of verbal memory and learning in antipsychotic-naive patients with first-episode schizophrenia. Schizophr. Res. 68:127-36 (Pubitemid 38526137)
-
(2004)
Schizophrenia Research
, vol.68
, Issue.2-3
, pp. 127-136
-
-
Hill, S.K.1
Beers, S.R.2
Kmiec, J.A.3
Keshavan, M.S.4
Sweeney, J.A.5
-
30
-
-
0028144551
-
Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia
-
Saykin AJ, Shtasel DL, Gur RE, Kester DB, Mozley LH, et al. 1994. Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia. Arch. Gen. Psychiatry 51:124-31
-
(1994)
Arch. Gen. Psychiatry
, vol.51
, pp. 124-31
-
-
Saykin, A.J.1
Shtasel, D.L.2
Gur, R.E.3
Kester, D.B.4
Mozley, L.H.5
-
31
-
-
4544289275
-
Neuropsychological functioning in first-break, never-medicated adolescents with psychosis
-
DOI 10.1097/01.nmd.0000138229.29157.3e
-
Brickman AM, Buchsbaum MS, Bloom R, Bokhoven P, Paul-Odouard R, et al. 2004. Neuropsychological functioning in first-break, never-medicated adolescents with psychosis. J. Nerv. Men. Dis. 192:615-22 (Pubitemid 39238409)
-
(2004)
Journal of Nervous and Mental Disease
, vol.192
, Issue.9
, pp. 615-622
-
-
Brickman, A.M.1
Buchsbaum, M.S.2
Bloom, R.3
Bokhoven, P.4
Paul-Odouard, R.5
Haznedar, M.M.6
Dahlman, K.L.7
Hazlett, E.A.8
Aronowitz, J.9
Heath, D.10
Shihabuddin, L.11
-
32
-
-
0242575290
-
The Maudsley Early-Onset Schizophrenia Study: Cognitive function in adolescent-onset schizophrenia
-
DOI 10.1016/S0920-9964(03)00067-7
-
Kravariti E, Morris RG, Rabe-Hesketh S, Murray RM, Frangou S. 2003. The Maudsley Early-Onset Schizophrenia Study: cognitive function in adolescent-onset schizophrenia. Schizophr. Res. 65:95-103 (Pubitemid 37434016)
-
(2003)
Schizophrenia Research
, vol.65
, Issue.2-3
, pp. 95-103
-
-
Kravariti, E.1
Morris, R.G.2
Rabe-Hesketh, S.3
Murray, R.M.4
Frangou, S.5
-
33
-
-
12944312691
-
Familial cognitive deficits in schizophrenia
-
DOI 10.1002/ajmg.b.30120
-
Hoff AL, Svetina C, Maurizio AM, Crow TJ, Spokes K, DeLisi LE. 2005. Familial cognitive deficits in schizophrenia. Am. J. Med. Genet. B Neuropsychiatr. Genet. 133B:43-49 (Pubitemid 40175613)
-
(2005)
American Journal of Medical Genetics - Neuropsychiatric Genetics
, vol.B
, Issue.1
, pp. 43-49
-
-
Hoff, A.L.1
Svetina, C.2
Maurizio, A.M.3
Crow, T.J.4
Spokes, K.5
DeLisi, L.E.6
-
34
-
-
0037044009
-
Spatial working memory deficits in schizophrenia patients and their first degree relatives from Palau, Micronesia
-
Myles-Worsley M, Park S. 2002. Spatial working memory deficits in schizophrenia patients and their first degree relatives from Palau, Micronesia. Am. J. Med. Genet. Neuropsychiatr. Genet. 114:609-15
-
(2002)
Am. J. Med. Genet. Neuropsychiatr. Genet.
, vol.114
, pp. 609-15
-
-
Myles-Worsley, M.1
Park, S.2
-
35
-
-
3042714417
-
A prospective study of childhood neurocognitive functioning in schizophrenic patients and their siblings
-
DOI 10.1176/appi.ajp.160.11.2060
-
Niendam TA, Bearden CE, Rosso IM, Sanchez LE, Hadley T, et al. 2003. A prospective study of childhood neurocognitive functioning in schizophrenic patients and their siblings. Am. J. Psychiatry 160:2060-62 (Pubitemid 39619649)
-
(2003)
American Journal of Psychiatry
, vol.160
, Issue.11
, pp. 2060-2062
-
-
Niendam, T.A.1
Bearden, C.E.2
Rosso, I.M.3
Sanchez, L.E.4
Hadley, T.5
Nuechterlein, K.H.6
Cannon, T.D.7
-
36
-
-
11844261436
-
Memory impairments identified in people at ultra-high risk for psychosis who later develop first-episode psychosis
-
DOI 10.1176/appi.ajp.162.1.71
-
Brewer WJ, Francey SM, Wood SJ, Jackson HJ, Pantelis C, et al. 2005. Memory impairments identified in people at ultra-high risk for psychosis who later develop first-episode psychosis. Am. J. Psychiatry 162:71-78 (Pubitemid 40095675)
-
(2005)
American Journal of Psychiatry
, vol.162
, Issue.1
, pp. 71-78
-
-
Brewer, W.J.1
Francey, S.M.2
Wood, S.J.3
Jackson, H.J.4
Pantelis, C.5
Phillips, L.J.6
Yung, A.R.7
Anderson, V.A.8
McGorry, P.D.9
-
37
-
-
0030980583
-
Neuropsychological evidence supporting a neurodevelopmental model of schizophrenia: A longitudinal study
-
DOI 10.1016/S0920-9964(96)00091-6, PII S0920996496000916
-
Censits DM, Ragland JD, Gur RC, Gur RE. 1997. Neuropsychological evidence supporting a neurode-velopmental model of schizophrenia: a longitudinal study. Schizophr. Res. 24:289-98 (Pubitemid 27163240)
-
(1997)
Schizophrenia Research
, vol.24
, Issue.3
, pp. 289-298
-
-
Censits, D.M.1
Ragland, J.D.2
Gur, R.C.3
Gur, R.E.4
-
38
-
-
0029842445
-
Effects of neuroleptic medications on the cognition of patients with schizophrenia: A review of recent studies
-
Goldberg TE, Weinberger DR. 1996. Effects of neuroleptic medications on the cognition of patients with schizophrenia: a review of recent studies. J. Clin. Psychiatry 57:62-65 (Pubitemid 26327760)
-
(1996)
Journal of Clinical Psychiatry
, vol.57
, Issue.SUPPL. 9
, pp. 62-65
-
-
Goldberg, T.E.1
Weinberger, D.R.2
-
39
-
-
0027181040
-
Information processing and attention dysfunctions in schizophrenia
-
Braff DL. 1993. Information processing and attention dysfunctions in schizophrenia. Schizophr. Bull. 19:233-59 (Pubitemid 23183147)
-
(1993)
Schizophrenia Bulletin
, vol.19
, Issue.2
, pp. 233-259
-
-
Braff, D.L.1
-
40
-
-
0031647089
-
Serotonin neurotoxicity: Implications for cognitive neuroscience and neurology
-
D'Esposito M. 1998. Serotonin neurotoxicity: implications for cognitive neuroscience and neurology. Neurology 51:1529-30 (Pubitemid 28565226)
-
(1998)
Neurology
, vol.51
, Issue.6
, pp. 1529-1530
-
-
D'Esposito, M.1
-
41
-
-
1842525247
-
General and specific cognitive deficits in schizophrenia
-
DOI 10.1016/j.biopsych.2003.12.010, PII S000632230400006X
-
Dickinson D, Iannone VN, Wilk CM, Gold JM. 2004. General and specific cognitive deficits in schizophrenia. Biol. Psychiatry 55:826-33 (Pubitemid 38429874)
-
(2004)
Biological Psychiatry
, vol.55
, Issue.8
, pp. 826-833
-
-
Dickinson, D.1
Iannone, V.N.2
Wilk, C.M.3
Gold, J.M.4
-
42
-
-
0034773263
-
Computerized neurocognitive scanning: II. The profile of schizophrenia
-
DOI 10.1016/S0893-133X(01)00279-2, PII S0893133X01002792
-
Gur RC, Ragland JD, Moberg PJ, Bilker WB, Kohler C, et al. 2001. Computerized neurocognitive scanning: II. The profile of schizophrenia. Neuropsychopharmacology 25:777-88 (Pubitemid 32995960)
-
(2001)
Neuropsychopharmacology
, vol.25
, Issue.5
, pp. 777-788
-
-
Gur, R.C.1
Ragland J.Daniel2
Moberg, P.J.3
Bilker, W.B.4
Kohler, C.5
Siegel, S.J.6
Gur, R.E.7
-
43
-
-
0031903740
-
Neurocognitive deficit in schizophrenia: A quantitative review of the evidence
-
DOI 10.1037/0894-4105.12.3.426
-
Heinrichs RW, Zakzanis KK. 1998. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology 12:426-45 (Pubitemid 28323862)
-
(1998)
Neuropsychology
, vol.12
, Issue.3
, pp. 426-445
-
-
Heinrichs, R.W.1
Zakzanis, K.K.2
-
44
-
-
7544234237
-
Identification of separable cognitive factors in schizophrenia
-
DOI 10.1016/j.schres.2004.09.007, PII S0920996404003421
-
Nuechterlein KH, Barch DM, Gold JM, Goldberg TE, Green MF, Heaton RK. 2004. Identification of separable cognitive factors in schizophrenia. Schizophr. Res. 72:29-39 (Pubitemid 39452903)
-
(2004)
Schizophrenia Research
, vol.72
, Issue.1
, pp. 29-39
-
-
Nuechterlein, K.H.1
Barch, D.M.2
Gold, J.M.3
Goldberg, T.E.4
Green, M.F.5
Heaton, R.K.6
-
45
-
-
7244245345
-
Identification of tone duration, line length, and letter position: An experimental approach to timing and working memory deficits in schizophrenia
-
DOI 10.1037/0021-843X.113.4.509
-
Elvevag B, Brown GDA, McCormack T, Vousden JI, Goldberg TE. 2004. Identification of tone duration, line length, and letter position: an experimental approach to timing and working memory deficits in schizophrenia. J. Abnorm. Psychol. 113:509-21 (Pubitemid 39431106)
-
(2004)
Journal of Abnormal Psychology
, vol.113
, Issue.4
, pp. 509-521
-
-
Elvevag, B.1
McCormack, T.2
Brown, G.D.A.3
Vousden, J.I.4
Goldberg, T.E.5
-
46
-
-
0033866340
-
The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia
-
DOI 10.1086/303006
-
Cannon TD, Huttunen MO, Lonnqvist J, Tuulio-Henriksson A, Pirkola T, et al. 2000. The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia. Am. J. Hum. Genet. 67:369-82 (Pubitemid 30616742)
-
(2000)
American Journal of Human Genetics
, vol.67
, Issue.2
, pp. 369-382
-
-
Cannon, T.D.1
Huttunen, M.O.2
Lonnqvist, J.3
Tuulio-Henriksson, A.4
Pirkola, T.5
Glahn, D.6
Finkelstein, J.7
Hietanen, M.8
Kaprio, J.9
Koskenvuo, M.10
-
47
-
-
0035810850
-
108/158 Met genotype on frontal lobe function and risk for schizophrenia
-
DOI 10.1073/pnas.111134598
-
108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc. Natl. Acad. Sci. USA 98:6917-22 (Pubitemid 32538317)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.12
, pp. 6917-6922
-
-
Egan, M.F.1
Goldberg, T.E.2
Kolachana, B.S.3
Callicott, J.H.4
Mazzanti, C.M.5
Straub, R.E.6
Goldman, D.7
Weinberger, D.R.8
-
48
-
-
0034029845
-
Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the 'right stuff'?
-
Green MF, Kern RS, Braff DL, Mintz J. 2000. Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the "right stuff "? Schizophr. Bull. 26:119-36 (Pubitemid 30317696)
-
(2000)
Schizophrenia Bulletin
, vol.26
, Issue.1
, pp. 119-136
-
-
Green, M.F.1
Kern, R.S.2
Braff, D.L.3
Mintz, J.4
-
49
-
-
0025879236
-
Neuropsychological function in schizophrenia: Selective impairment in memory and learning
-
Saykin AJ, Gur RC, Gur RE, Mozley PD, Mozley LH, et al. 1991. Neuropsychological function in schizophrenia: selective impairment in memory and learning. Arch. Gen. Psychiatry 48:618-24
-
(1991)
Arch. Gen. Psychiatry
, vol.48
, pp. 618-24
-
-
Saykin, A.J.1
Gur, R.C.2
Gur, R.E.3
Mozley, P.D.4
Mozley, L.H.5
-
50
-
-
0031750915
-
"cognitive dysmetria" as anintegrative theoryofschizophre-nia: A dysfunction in cortical-subcortical-cerebellar circuitry?
-
Andreasen N, Paradiso S,O'Leary D. 1998. "Cognitive dysmetria"as anintegrative theoryofschizophre-nia: a dysfunction in cortical-subcortical-cerebellar circuitry? Schizophr. Bull. 24:203-18
-
(1998)
Schizophr. Bull.
, vol.24
, pp. 203-18
-
-
Andreasen, N.1
Paradiso So'Leary, D.2
-
51
-
-
0032746530
-
Alteration of intention and self-initiated action associated with bilateral anterior cingulotomy
-
Cohen RA, Kaplan RF, Zuffante P, Moser DJ, Jenkins MA, et al. 1999. Alteration of intention and self-initiated action associated with bilateral anterior cingulotomy.J. Neuropsychiatry Clin. Neurosci.11:444-53
-
(1999)
J. Neuropsychiatry Clin. Neurosci.
, vol.11
, pp. 444-53
-
-
Cohen, R.A.1
Kaplan, R.F.2
Zuffante, P.3
Moser, D.J.4
Jenkins, M.A.5
-
53
-
-
0029918481
-
What are the functional consequences of neurocognitive deficits in schizophrenia?
-
Green MF. 1996. What are the functional consequences of neurocognitive deficits in schizophrenia? Am. J. Psychiatry 153:321-30 (Pubitemid 26074706)
-
(1996)
American Journal of Psychiatry
, vol.153
, Issue.3
, pp. 321-330
-
-
Green, M.F.1
-
55
-
-
84885186331
-
Principles of the pharmacotherapy of schizophrenia
-
ed. DS Charney, EJ Nestler New York: Oxford Univ. Press. 3rd ed.
-
Tamminga CA. 2008. Principles of the pharmacotherapy of schizophrenia. In Neurobiology of Mental Illness, ed. DS Charney, EJ Nestler, pp. 329-47. New York: Oxford Univ. Press. 3rd ed.
-
(2008)
Neurobiology of Mental Illness
, pp. 329-47
-
-
Tamminga, C.A.1
-
56
-
-
0026516298
-
General pharmacology of clozapine
-
Coward DM. 1992. General pharmacology of clozapine. Br. J. Psychiatry Suppl. 17:5-11
-
(1992)
Br. J. Psychiatry Suppl.
, vol.17
, pp. 5-11
-
-
Coward, D.M.1
-
57
-
-
0038653525
-
A meta-analysis of the efficacy of second-generation antipsychotics
-
DOI 10.1001/archpsyc.60.6.553
-
Davis JM, Chen N, Glick ID. 2003. A meta-analysis of the efficacy of second-generation antipsychotics. Arch. Gen. Psychiatry 60:553-64; comment 63:935-37, author reply 937-39 (Pubitemid 36682312)
-
(2003)
Archives of General Psychiatry
, vol.60
, Issue.6
, pp. 553-564
-
-
Davis, J.M.1
Chen, N.2
Glick, I.D.3
-
58
-
-
25144456112
-
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
-
DOI 10.1056/NEJMoa051688
-
Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, et al. 2005. Effectiveness of antipsy-chotic drugs in patients with chronic schizophrenia. N. Engl. J. Med. 353:1209-23 (Pubitemid 41345943)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.12
, pp. 1209-1223
-
-
Lieberman, J.A.1
Scott Stroup, T.2
McEvoy, J.P.3
Swartz, M.S.4
Rosenheck, R.A.5
Perkins, D.O.6
Keefe, R.S.E.7
Davis, S.M.8
Davis, C.E.9
Lebowitz, B.D.10
Severe, J.11
Hsiao, J.K.12
-
59
-
-
0042882529
-
Comparative efficacy and safety of atypical and conventional antipsychotic drugs in first-episode psychosis: A randomized, double-blind trial of olanzapine versus haloperidol
-
DOI 10.1176/appi.ajp.160.8.1396
-
Lieberman JA, Tollefson G, Tohen M, Green AI, Gur RE, et al. 2003. Comparative efficacy and safety of atypical and conventional antipsychotic drugs in first-episode psychosis: a randomized, double-blind trial of olanzapine versus haloperidol. Am. J. Psychiatry 160:1396-404 (Pubitemid 41070913)
-
(2003)
American Journal of Psychiatry
, vol.160
, Issue.8
, pp. 1396-1404
-
-
Lieberman, J.A.1
Tollefson, G.2
Tohen, M.3
Green, A.I.4
Gur, R.E.5
Kahn, R.6
McEvoy, J.7
Perkins, D.8
Sharma, T.9
Zipursky, R.10
Wei, H.11
Hamer, R.M.12
-
61
-
-
0038618835
-
Partial dopamine agonists and dopaminergic stabilizers, in the treatment of psychosis
-
Tamminga CA, Carlsson A. 2002. Partial dopamine agonists and dopaminergic stabilizers, in the treatment of psychosis. Curr. Drug Targets CNS Neurol. Disord. 1:141-47
-
(2002)
Curr. Drug Targets CNS Neurol. Disord.
, vol.1
, pp. 141-47
-
-
Tamminga, C.A.1
Carlsson, A.2
-
62
-
-
0035667156
-
Management of treatment resistance in schizophrenia
-
DOI 10.1016/S0006-3223(01)01271-9, PII S0006322301012719
-
Conley RR, Kelly DL. 2001. Management of treatment resistance in schizophrenia. Biol. Psychiatry 50:898-911 (Pubitemid 34020701)
-
(2001)
Biological Psychiatry
, vol.50
, Issue.11
, pp. 898-911
-
-
Conley, R.R.1
Kelly, D.L.2
-
63
-
-
0036202379
-
Partial dopamine agonists in the treatment of psychosis
-
DOI 10.1007/s007020200033
-
Tamminga CA. 2002. Partial dopamine agonists in the treatment of psychosis. J. Neural Transm. 109:411-20 (Pubitemid 34251643)
-
(2002)
Journal of Neural Transmission
, vol.109
, Issue.3
, pp. 411-420
-
-
Tamminga, C.A.1
-
64
-
-
48949095543
-
Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia
-
Shekhar A, Potter WZ, Lightfoot J, Lienemann J, Dube S, et al. 2008. Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia. Am. J. Psychiatry 165:1033-39
-
(2008)
Am. J. Psychiatry
, vol.165
, pp. 1033-39
-
-
Shekhar, A.1
Potter, W.Z.2
Lightfoot, J.3
Lienemann, J.4
Dube, S.5
-
66
-
-
59749100417
-
Antipsychotic properties of muscarinic drugs
-
Janowsky DS, Davis JM. 2009. Antipsychotic properties of muscarinic drugs. Am. J. Psychiatry 166:110-11
-
(2009)
Am. J. Psychiatry
, vol.166
, pp. 110-11
-
-
Janowsky, D.S.1
Davis, J.M.2
-
67
-
-
34948816146
-
Erratum: Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial (Nature Medicine (2007) 13, (1102-1107))
-
DOI 10.1038/nm1007-1264, PII NM10071264
-
Patil ST, Zhang L, Martenyi F, Lowe SL, Jackson KA, et al. 2007. Corrigenda: Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat. Med. 13:1264 (Pubitemid 47530624)
-
(2007)
Nature Medicine
, vol.13
, Issue.10
, pp. 1264
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
Lowe, S.L.4
Jackson, K.A.5
Andreev, B.V.6
Avedisova, A.S.7
Bardenstein, L.M.8
Gurovich, I.Y.9
Morozova, M.A.10
Mosolov, S.N.11
Neznanov, N.G.12
Reznik, A.M.13
Smulevich, A.B.14
Tochilov, V.A.15
Johnson, B.G.16
Monn, J.A.17
Schoepp, D.D.18
-
68
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
-
DOI 10.1038/nm1632, PII NM1632
-
Patil ST, Zhang L, Martenyi F, Lowe SL, Jackson KA, et al. 2007. Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat. Med. 13:1102-7 (Pubitemid 47517511)
-
(2007)
Nature Medicine
, vol.13
, Issue.9
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
Lowe, S.L.4
Jackson, K.A.5
Andreev, B.V.6
Avedisova, A.S.7
Bardenstein, L.M.8
Gurovich, I.Y.9
Morozova, M.A.10
Mosolov, S.N.11
Neznanov, N.G.12
Reznik, A.M.13
Smulevich, A.B.14
Tochilov, V.A.15
Johnson, B.G.16
Monn, J.A.17
Schoepp, D.D.18
-
69
-
-
0025613142
-
Basal ganglia-thalamocortical circuits: Parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions
-
Alexander GE, Crutcher MD, DeLong MR. 1990. Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions. Prog. Brain Res. 85:119-46
-
(1990)
Prog. Brain Res.
, vol.85
, pp. 119-46
-
-
Alexander, G.E.1
Crutcher, M.D.2
Delong, M.R.3
-
70
-
-
0025298139
-
Primate models of movement disorders of basal ganglia origin
-
DeLong MR. 1990. Primate models of movement disorders of basal ganglia origin. Trends Neurosci. 13:281-85
-
(1990)
Trends Neurosci.
, vol.13
, pp. 281-85
-
-
Delong, M.R.1
-
71
-
-
0029918481
-
What are the functional consequences of neurocognitive deficits in schizophrenia?
-
Green MF. 1996. What are the functional consequences of neurocognitive deficits in schizophrenia? Am. J. Psychiatry 153:321-30 (Pubitemid 26074706)
-
(1996)
American Journal of Psychiatry
, vol.153
, Issue.3
, pp. 321-330
-
-
Green, M.F.1
-
72
-
-
26444587625
-
Distinguishing separable domains of cognition in human and animal studies: What separations are optimal for targeting interventions? A summary of recommendations from breakout group 2 at the Measurement and Treatment Research to Improve Cognition in Schizophrenia New Approaches Conference
-
DOI 10.1093/schbul/sbi047
-
Nuechterlein KH, Robbins TW, Einat H. 2005. Distinguishing separable domains of cognition in human and animal studies: What separations are optimal for targeting interventions? A summary of recommendations from breakout group 2 at the Measurement and Treatment Research to Improve Cognition in Schizophrenia New Approaches Conference. Schizophr. Bull. 31:870-74 (Pubitemid 41437780)
-
(2005)
Schizophrenia Bulletin
, vol.31
, Issue.4
, pp. 870-874
-
-
Nuechterlein, K.H.1
Robbins, T.W.2
Einat, H.3
-
73
-
-
3142761435
-
Alpha-7 nicotinic receptor agonists: Potential new candidates for the treatment of schizophrenia
-
Martin LF, Kem WR, Freedman R. 2004. α7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia. Psychopharmacology 174:54-64 (Pubitemid 38925091)
-
(2004)
Psychopharmacology
, vol.174
, Issue.1
, pp. 54-64
-
-
Martin, L.F.1
Kem, W.R.2
Freedman, R.3
-
74
-
-
33744911665
-
Proof-of-concept trial of an α7 nicotinic agonist in schizophrenia
-
DOI 10.1001/archpsyc.63.6.630
-
Olincy A, Harris JG, Johnson LL, Pender V, Kongs S, et al. 2006. Proof-of-concept trial of an α7 nicotinic agonist in schizophrenia. Arch. Gen. Psychiatry 63:630-38 (Pubitemid 43848294)
-
(2006)
Archives of General Psychiatry
, vol.63
, Issue.6
, pp. 630-638
-
-
Olincy, A.1
Harris, J.G.2
Johnson, L.L.3
Pender, V.4
Kongs, S.5
Allensworth, D.6
Ellis, J.7
Zerbe, G.O.8
Leonard, S.9
Stevens, K.E.10
Stevens, J.O.11
Martin, L.12
Adler, L.E.13
Soti, F.14
Kem, W.R.15
Freedman, R.16
-
75
-
-
48949099564
-
Initial phase 2 trial of a nicotinic agonist in schizophrenia
-
Freedman R, Olincy A, Buchanan RW, Harris JG, Gold JM, et al. 2008. Initial phase 2 trial of a nicotinic agonist in schizophrenia. Am. J. Psychiatry 165:1040-47
-
(2008)
Am. J. Psychiatry
, vol.165
, pp. 1040-47
-
-
Freedman, R.1
Olincy, A.2
Buchanan, R.W.3
Harris, J.G.4
Gold, J.M.5
-
76
-
-
0034934938
-
Cholinergic systems and schizophrenia: Primary pathology or epiphenomena?
-
DOI 10.1016/S0891-0618(01)00101-6, PII S0891061801001016
-
Hyde TM, Crook JM. 2001. Cholinergic systems and schizophrenia: primary pathology or epiphenom-ena? J. Chem. Neuroanat. 22:53-63 (Pubitemid 32695509)
-
(2001)
Journal of Chemical Neuroanatomy
, vol.22
, Issue.1-2
, pp. 53-63
-
-
Hyde, T.M.1
Crook, J.M.2
-
77
-
-
0034282537
-
Decreased muscarinic receptor binding in subjects with schizophrenia: A study of the human hippocampal formation
-
Crook JM, Tomaskovic-Crook E, Copolov DL, Dean B. 2000. Decreased muscarinic receptor binding in subjects with schizophrenia: a study of the human hippocampal formation. Soc. Biol. Psychiatry 48:381-88
-
(2000)
Soc. Biol. Psychiatry
, vol.48
, pp. 381-88
-
-
Crook, J.M.1
Tomaskovic-Crook, E.2
Copolov, D.L.3
Dean, B.4
-
78
-
-
3142746642
-
Cholinergic targets for cognitive enhancement in schizophrenia: Focus on cholinesterase inhibitors and muscarinic agonists
-
Friedman JI. 2004. Cholinergic targets for cognitive enhancement in schizophrenia: focus on cholinesterase inhibitors and muscarinic agonists. Psychopharmacology 174:45-53 (Pubitemid 38925090)
-
(2004)
Psychopharmacology
, vol.174
, Issue.1
, pp. 45-53
-
-
Friedman, J.I.1
-
79
-
-
0041819609
-
Reduced expression of the muscarinic 1 receptor cortical subtype in schizophrenia
-
Mancama D, Arranz MJ, Landau S, Kerwin R. 2003. Reduced expression of the muscarinic 1 receptor cortical subtype in schizophrenia. Am. J. Med. Genet. B Neuropsychiatr. Genet. 119B:2-6 (Pubitemid 37064044)
-
(2003)
American Journal of Medical Genetics - Neuropsychiatric Genetics
, vol.B
, Issue.1
, pp. 2-6
-
-
Mancama, D.1
Arranz, M.J.2
Landau, S.3
Kerwin, R.4
-
80
-
-
16844363204
-
1 agonism a pre-requisite for mimicking clozapine's actions?
-
DOI 10.1007/s00213-004-2017-1
-
Davies MA, Compton-Toth BA, Hufeisen SJ, Meltzer HY, Roth BL. 2005. The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: Is M1 agonism a prerequisite for mimicking clozapine's actions? Psychopharmacology 178:451-60 (Pubitemid 40486985)
-
(2005)
Psychopharmacology
, vol.178
, Issue.4
, pp. 451-460
-
-
Davies, M.A.1
Compton-Toth, B.A.2
Hufeisen, S.J.3
Meltzer, H.Y.4
Roth, B.L.5
-
81
-
-
48949095543
-
Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia
-
Shekhar A, Potter WZ, Lightfoot J, Lienemann J, Dubé S, et al. 2008. Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia. Am. J. Psychiatry 165:1033-39
-
(2008)
Am. J. Psychiatry
, vol.165
, pp. 1033-39
-
-
Shekhar, A.1
Potter, W.Z.2
Lightfoot, J.3
Lienemann, J.4
Dubé, S.5
-
82
-
-
27744476275
-
3 partial agonist
-
DOI 10.1124/jpet.105.092155
-
3 partial agonist. J. Pharmacol. Exp. Ther. 315:1278-87 (Pubitemid 41635416)
-
(2005)
Journal of Pharmacology and Experimental Therapeutics
, vol.315
, Issue.3
, pp. 1278-1287
-
-
Burstein, E.S.1
Ma, J.2
Wong, S.3
Gao, Y.4
Pham, E.5
Knapp, A.E.6
Nash, N.R.7
Olsson, R.8
Davis, R.E.9
Hacksell, U.10
Weiner, D.M.11
Brann, M.R.12
-
83
-
-
19944426901
-
The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine
-
DOI 10.1007/s00213-004-1940-5
-
Weiner DM, Meltzer HY, Veinbergs I, Donohue EM, Spalding TA, et al. 2004. The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine. Psychopharmacology 177:207-16 (Pubitemid 40109932)
-
(2004)
Psychopharmacology
, vol.177
, Issue.1-2
, pp. 207-216
-
-
Weiner, D.M.1
Meltzer, H.Y.2
Veinbergs, I.3
Donohue, E.M.4
Spalding, T.A.5
Smith, T.T.6
Mohell, N.7
Harvey, S.C.8
Lameh, J.9
Nash, N.10
Vanover, K.E.11
Olsson, R.12
Jayathilake, K.13
Lee, M.14
Levey, A.I.15
Hacksell, U.16
Burstein, E.S.17
Davis, R.E.18
Brann, M.R.19
-
84
-
-
79951990555
-
ACP104 initial phase II results: Putative antipsychotic drug and cognition enhancer
-
Presented at 45th, Hollywood, Fla.
-
Tamminga CA, Ibrahim HM, Eamma J, Corritorri S, Nichols A, et al. 2006. ACP104 initial phase II results: putative antipsychotic drug and cognition enhancer. Presented at Ann. Meet. Am. Coll. Neuropsy-chopharmacol., 45th, Hollywood, Fla.
-
(2006)
Ann. Meet. Am. Coll. Neuropsy-chopharmacol.
-
-
Tamminga, C.A.1
Ibrahim, H.M.2
Eamma, J.3
Corritorri, S.4
Nichols, A.5
-
86
-
-
0037444648
-
Catechol-O-methyltransferase genotype and dopamine regulation in the human brain
-
Akil M, Kolachana BS, Rothmond DA, Hyde TM, Weinberger DR, Kleinman JE. 2003. Catechol-O-methyltransferase genotype and dopamine regulation in the human brain. J. Neurosci. 23:2008-13 (Pubitemid 36368887)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.6
, pp. 2008-2013
-
-
Akil, M.1
Kolachana, B.S.2
Rothmond, D.A.3
Hyde, T.M.4
Weinberger, D.R.5
Kleinman, J.E.6
-
89
-
-
0038488945
-
Aripiprazole, an antipsychotic with a novel mechanism of action, and risperidone vs placebo in patients with schizophrenia and schizoaffective disorder
-
DOI 10.1001/archpsyc.60.7.681
-
Potkin SG, Saha AR, Kujawa MJ, Carson WH, Ali M, et al. 2003. Aripiprazole, an antipsychotic with a novel mechanism of action, and risperidone versus placebo in patients with schizophrenia and schizoaf-fective disorder. Arch. Gen. Psychiatry 60:681-90 (Pubitemid 36818630)
-
(2003)
Archives of General Psychiatry
, vol.60
, Issue.7
, pp. 681-690
-
-
Potkin, S.G.1
Saha, A.R.2
Kujawa, M.J.3
Carson, W.H.4
Ali, M.5
Stock, E.6
Stringfellow, J.7
Ingenito, G.8
Marder, S.R.9
-
90
-
-
0028825345
-
Abnormally high neuronal density in the schizophrenic cortex: A morphometric analysis of prefrontal area 9 and occipital area 17
-
Selemon LD, Rajkowska G, Goldman-Rakic PS. 1995. Abnormally high neuronal density in the schizophrenic cortex: a morphometric analysis of prefrontal area 9 and occipital area 17. Arch. Gen. Psychiatry 52:805-18
-
(1995)
Arch. Gen. Psychiatry
, vol.52
, pp. 805-18
-
-
Selemon, L.D.1
Rajkowska, G.2
Goldman-Rakic, P.S.3
-
91
-
-
34249319444
-
1 agonist, is safe and tolerated in patients with schizophrenia
-
DOI 10.1016/j.schres.2007.03.011, PII S0920996407001193
-
1 agonist, is safe and tolerated in patients with schizophrenia. Schizophr. Res. 93:42-50 (Pubitemid 46817947)
-
(2007)
Schizophrenia Research
, vol.93
, Issue.1-3
, pp. 42-50
-
-
George, M.S.1
Molnar, C.E.2
Grenesko, E.L.3
Anderson, B.4
Mu, Q.5
Johnson, K.6
Nahas, Z.7
Knable, M.8
Fernandes, P.9
Juncos, J.10
Huang, X.11
Nichols, D.E.12
Mailman, R.B.13
-
92
-
-
34447252651
-
1 dopamine agonist dihydrexidine (DAR-0100) increases prefrontal perfusion in schizophrenia
-
DOI 10.1016/j.schres.2007.03.033, PII S0920996407001284
-
1 dopamine agonist dihydrexidine (DAR-0100) increases prefrontal perfusion in schizophrenia. Schizophr. Res. 94:332-41 (Pubitemid 47039290)
-
(2007)
Schizophrenia Research
, vol.94
, Issue.1-3
, pp. 332-341
-
-
Mu, Q.1
Johnson, K.2
Morgan, P.S.3
Grenesko, E.L.4
Molnar, C.E.5
Anderson, B.6
Nahas, Z.7
Kozel, F.A.8
Kose, S.9
Knable, M.10
Fernandes, P.11
Nichols, D.E.12
Mailman, R.B.13
George, M.S.14
-
93
-
-
66349085040
-
A randomized double-blind trial of atomoxetine for cognitive impairments in 32 people with schizophrenia
-
Kelly DL, Buchanan RW, Boggs DL, McMahon RP, Dickinson D, et al. 2009. A randomized double-blind trial of atomoxetine for cognitive impairments in 32 people with schizophrenia. J. Clin. Psychiatry 70:518-25
-
(2009)
J. Clin. Psychiatry
, vol.70
, pp. 518-25
-
-
Kelly, D.L.1
Buchanan, R.W.2
Boggs, D.L.3
McMahon, R.P.4
Dickinson, D.5
-
94
-
-
38349142770
-
A pilot study of adjunctive atomoxe-tine treatment to second-generation antipsychotics for cognitive impairment in schizophrenia
-
Friedman JI, Carpenter D, Lu J, Fan J, Tang CY, et al. 2008. A pilot study of adjunctive atomoxe-tine treatment to second-generation antipsychotics for cognitive impairment in schizophrenia. J. Clin. Psychopharmacol. 28:59-63
-
(2008)
J. Clin. Psychopharmacol.
, vol.28
, pp. 59-63
-
-
Friedman, J.I.1
Carpenter, D.2
Lu, J.3
Fan, J.4
Tang, C.Y.5
-
95
-
-
0034851624
-
Effects of ketamine in normal and schizophrenic volunteers
-
DOI 10.1016/S0893-133X(01)00243-3, PII S0893133X01002433
-
Lahti AC, Weiler MA, Tamara Michaelidis BA, Parwani A, Tamminga CA. 2001. Effects of ketamine in normal and schizophrenic volunteers. Neuropsychopharmacology 25:455-67 (Pubitemid 32830950)
-
(2001)
Neuropsychopharmacology
, vol.25
, Issue.4
, pp. 455-467
-
-
Lahti, A.C.1
Weiler, M.A.2
Michaelidis, T.3
Parwani, A.4
Tamminga, C.A.5
-
96
-
-
0033021280
-
Glutamatergic aspects of schizophrenia
-
Tamminga C. 1999. Glutamatergic aspects of schizophrenia. Br. J. Psychiatry Suppl. 37:12-15 (Pubitemid 29089304)
-
(1999)
British Journal of Psychiatry
, vol.174
, Issue.FEB. SUPPL. 37
, pp. 12-15
-
-
Tamminga, C.1
-
97
-
-
0028323167
-
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
-
Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, et al. 1994. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch. Gen. Psychiatry 51:199-214 (Pubitemid 24081509)
-
(1994)
Archives of General Psychiatry
, vol.51
, Issue.3
, pp. 199-214
-
-
Krystal, J.H.1
Karper, L.P.2
Seibyl, J.P.3
Freeman, G.K.4
Delaney, R.5
Bremner, J.D.6
Heninger, G.R.7
Bowers Jr., M.B.8
Charney, D.S.9
-
98
-
-
0028875197
-
Abnormal excitatory neurotransmitter metabolism in schizophrenic brains
-
Tsai G, Passani LA, Slusher BS, Carter R, Baer L, et al. 1995. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Arch. Gen. Psychiatry 52:829-36
-
(1995)
Arch. Gen. Psychiatry
, vol.52
, pp. 829-36
-
-
Tsai, G.1
Passani, L.A.2
Slusher, B.S.3
Carter, R.4
Baer, L.5
-
99
-
-
0033914752
-
Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: Effects of schizophrenia
-
DOI 10.1176/appi.ajp.157.7.1141
-
Gao XM, Sakai K, Roberts RC, Conley RR, Dean B, Tamminga CA. 2000. Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. Am. J. Psychiatry 157:1141-49 (Pubitemid 30432497)
-
(2000)
American Journal of Psychiatry
, vol.157
, Issue.7
, pp. 1141-1149
-
-
Gao, X.-M.1
Sakai, K.2
Roberts, R.C.3
Conley, R.R.4
Dean, B.5
Tamminga, C.A.6
-
100
-
-
77949447469
-
Strategies to enhance N-methyl-D-aspartate receptor-mediated neurotransmis-sion in schizophrenia, a critical review and meta-analysis
-
Tsai GE, Lin PY. 2009. Strategies to enhance N-methyl-D-aspartate receptor-mediated neurotransmis-sion in schizophrenia, a critical review and meta-analysis. Curr. Pharm. Des. 16:522-37
-
(2009)
Curr. Pharm. Des.
, vol.16
, pp. 522-37
-
-
Tsai, G.E.1
Lin, P.Y.2
-
102
-
-
61449150536
-
Effects of a metabotropic glutamate receptor group II agonist LY354740 in animal models of positive schizophrenia symptoms and cognition
-
Schlumberger C, Schafer D, Barberi C, More L, Nagel J, et al. 2009. Effects of a metabotropic glutamate receptor group II agonist LY354740 in animal models of positive schizophrenia symptoms and cognition. Behav. Pharmacol. 20:56-66
-
(2009)
Behav. Pharmacol.
, vol.20
, pp. 56-66
-
-
Schlumberger, C.1
Schafer, D.2
Barberi, C.3
More, L.4
Nagel, J.5
-
103
-
-
57349167353
-
Subunit-selective modulation of GABA type A receptor neurotransmission and cognition in schizophrenia
-
Lewis DA, Cho RY, Carter CS, Eklund K, Forster S, et al. 2008. Subunit-selective modulation of GABA type A receptor neurotransmission and cognition in schizophrenia. Am. J. Psychiatry 165:1585-93
-
(2008)
Am. J. Psychiatry
, vol.165
, pp. 1585-93
-
-
Lewis, D.A.1
Cho, R.Y.2
Carter, C.S.3
Eklund, K.4
Forster, S.5
-
106
-
-
0028107369
-
Event-related potential abnormalities correlate with structural brain alterations and clinical features in patients with chronic schizophrenia
-
DOI 10.1016/0920-9964(94)90020-5
-
Egan MF, Duncan CC, Suddath RL, Kirch DG, Mirsky AF, Wyatt RJ. 1994. Event-related potential abnormalities correlate with structural brain alterations and clinical features in patients with chronic schizophrenia. Schizophr. Res. 11:259-71 (Pubitemid 24063746)
-
(1994)
Schizophrenia Research
, vol.11
, Issue.3
, pp. 259-271
-
-
Egan, M.F.1
Duncan, C.C.2
Suddath, R.L.3
Kirch, D.G.4
Mirsky, A.F.5
Wyatt, R.J.6
-
107
-
-
0036159249
-
Neuropsychological correlates of hippocampal volumes in patients experiencing a first episode of schizophrenia
-
DOI 10.1176/appi.ajp.159.2.217
-
Szeszko PR, Strous RD, Goldman RS, Ashtari M, Knuth KH, et al. 2002. Neuropsychological correlates of hippocampal volumes in patients experiencing a first episode of schizophrenia. Am. J. Psychiatry 159:217-26 (Pubitemid 34126898)
-
(2002)
American Journal of Psychiatry
, vol.159
, Issue.2
, pp. 217-226
-
-
Szeszko, P.R.1
Strous, R.D.2
Goldman, R.S.3
Ashtari, M.4
Knuth, K.H.5
Lieberman, J.A.6
Bilder, R.M.7
-
108
-
-
34547659148
-
The genetic deconstruction of psychosis
-
DOI 10.1093/schbul/sbm053
-
Owen MJ, Craddock N, Jablensky A. 2007. The genetic deconstruction of psychosis. Schizophr. Bull. 33:905-11 (Pubitemid 47216654)
-
(2007)
Schizophrenia Bulletin
, vol.33
, Issue.4
, pp. 905-911
-
-
Owen, M.J.1
Craddock, N.2
Jablensky, A.3
-
109
-
-
68449096727
-
Common variants on chromosome 6p22.1 are associated with schizophrenia
-
Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, et al. 2009. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 460:753-57
-
(2009)
Nature
, vol.460
, pp. 753-57
-
-
Shi, J.1
Levinson, D.F.2
Duan, J.3
Sanders, A.R.4
Zheng, Y.5
-
110
-
-
68449090594
-
Common variants conferring risk of schizophrenia
-
Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, et al. 2009. Common variants conferring risk of schizophrenia. Nature 460:744-47
-
(2009)
Nature
, vol.460
, pp. 744-47
-
-
Stefansson, H.1
Ophoff, R.A.2
Steinberg, S.3
Andreassen, O.A.4
Cichon, S.5
-
111
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, et al. 2009. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460:748-52
-
(2009)
Nature
, vol.460
, pp. 748-52
-
-
Purcell, S.M.1
Wray, N.R.2
Stone, J.L.3
Visscher, P.M.4
O'Donovan, M.C.5
-
112
-
-
42349088634
-
Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
-
DOI 10.1126/science.1155174
-
Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, et al. 2008. Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 320:539-43 (Pubitemid 351590668)
-
(2008)
Science
, vol.320
, Issue.5875
, pp. 539-543
-
-
Walsh, T.1
McClellan, J.M.2
McCarthy, S.E.3
Addington, A.M.4
Pierce, S.B.5
Cooper, G.M.6
Nord, A.S.7
Kusenda, M.8
Malhotra, D.9
Bhandari, A.10
Stray, S.M.11
Rippey, C.F.12
Roccanova, P.13
Makarov, V.14
Lakshmi, B.15
Findling, R.L.16
Sikich, L.17
Stromberg, T.18
Merriman, B.19
Gogtay, N.20
Butler, P.21
Eckstrand, K.22
Noory, L.23
Gochman, P.24
Long, R.25
Chen, Z.26
Davis, S.27
Baker, C.28
Eichler, E.E.29
Meltzer, P.S.30
Nelson, S.F.31
Singleton, A.B.32
Lee, M.K.33
Rapoport, J.L.34
King, M.-C.35
Sebat, J.36
more..
-
113
-
-
49649097104
-
Genetics of clinical features and subtypes of schizophrenia: A review of the recent literature
-
Fanous AH, Kendler KS. 2008. Genetics of clinical features and subtypes of schizophrenia: a review of the recent literature. Curr. Psychiatry Rep. 10:164-70
-
(2008)
Curr. Psychiatry Rep.
, vol.10
, pp. 164-70
-
-
Fanous, A.H.1
Kendler, K.S.2
-
114
-
-
42749095376
-
Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
-
Lisman JE, Coyle JT, Green RW, Javitt DC, Benes FM, et al. 2008. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 31:234-42
-
(2008)
Trends Neurosci.
, vol.31
, pp. 234-42
-
-
Lisman, J.E.1
Coyle, J.T.2
Green, R.W.3
Javitt, D.C.4
Benes, F.M.5
-
115
-
-
33749645423
-
Cognitive dysfunction in schizophrenia: Convergence of γ-aminobutyric acid and glutamate alterations
-
DOI 10.1001/archneur.63.10.1372
-
Lewis DA, Moghaddam B. 2006. Cognitive dysfunction inschizophrenia: convergence ofγ-aminobutyric acid and glutamate alterations. Arch. Neurol. 63:1372-76 (Pubitemid 44547546)
-
(2006)
Archives of Neurology
, vol.63
, Issue.10
, pp. 1372-1376
-
-
Lewis, D.A.1
Moghaddam, B.2
-
116
-
-
33646152528
-
A dopaminergic deficit hypothesis of schizophrenia: The path to discovery
-
Carlsson A, Carlsson ML. 2006. A dopaminergic deficit hypothesis of schizophrenia: the path to discovery. Dialogues Clin. Neurosci. 8:137-42
-
(2006)
Dialogues Clin. Neurosci.
, vol.8
, pp. 137-42
-
-
Carlsson, A.1
Carlsson, M.L.2
-
117
-
-
33750322242
-
Six degrees of separation: On the prior probability that schizophrenia susceptibility genes converge on synapses, glutamate and NMDA receptors [2]
-
DOI 10.1038/sj.mp.4001886, PII 4001886
-
Harrison PJ, West VA. 2006. Six degrees of separation: on the prior probability that schizophrenia susceptibility genes converge on synapses, glutamate and NMDA receptors. Mol. Psychiatry 11:981-83 (Pubitemid 44631640)
-
(2006)
Molecular Psychiatry
, vol.11
, Issue.11
, pp. 981-983
-
-
Harrison, P.J.1
West, V.A.2
-
118
-
-
0030933984
-
Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia
-
DOI 10.1016/S0006-8993(96)01404-7, PII S0006899396014047
-
Porter RH, Eastwood SL, Harrison PJ. 1997. Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex, and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia. Brain Res. 751:217-31 (Pubitemid 27132551)
-
(1997)
Brain Research
, vol.751
, Issue.2
, pp. 217-231
-
-
Porter, R.H.P.1
Eastwood, S.L.2
Harrison, P.J.3
-
119
-
-
0035903772
-
Asymmetrical reductions of hippocampal NMDARI glutamate receptor mRNA in the psychoses
-
Law AJ, Deakin JF. 2001. Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. NeuroReport 12:2971-74 (Pubitemid 32882018)
-
(2001)
NeuroReport
, vol.12
, Issue.13
, pp. 2971-2974
-
-
Law, A.J.1
Deakin, J.F.W.2
-
120
-
-
0028907468
-
Decreased expression of mRNAs encoding non-NMDA glutamate receptors GluR1 and GluR2 in medial temporal lobe neurons in schizophrenia
-
Eastwood SL, McDonald B, Burnet PWJ, Beckwith JP, Kerwin RW, Harrison PJ. 1995. Decreased expression of mRNAs encoding non-NMDA glutamate receptors GluR1 and GluR2 in medial temporal lobe neurons in schizophrenia. Mol. Brain Res. 29:211-23
-
(1995)
Mol. Brain Res.
, vol.29
, pp. 211-23
-
-
Eastwood, S.L.1
McDonald, B.2
Pwj, B.3
Beckwith, J.P.4
Kerwin, R.W.5
Harrison, P.J.6
-
121
-
-
34250643126
-
Decreased numerical density of CA3 hippocampal mossy fiber synapses in schizophrenia
-
DOI 10.1002/syn.20405
-
Kolomeets NS, Orlovskaya DD, Uranova NA. 2007. Decreased numerical density of CA3 hippocampal mossy fiber synapses in schizophrenia. Synapse 61:615-21 (Pubitemid 46934008)
-
(2007)
Synapse
, vol.61
, Issue.8
, pp. 615-621
-
-
Kolomeets, N.S.1
Orlovskaya, D.D.2
Uranova, N.A.3
-
122
-
-
33646377899
-
Neural stem cell proliferation is decreased in schizophrenia, but not in depression
-
Reif A, Fritzen S, Finger M, Strobel A, Lauer M, et al. 2006. Neural stem cell proliferation is decreased in schizophrenia, but not in depression. Mol. Psychiatry 11:514-22
-
(2006)
Mol. Psychiatry
, vol.11
, pp. 514-22
-
-
Reif, A.1
Fritzen, S.2
Finger, M.3
Strobel, A.4
Lauer, M.5
-
123
-
-
0037441696
-
Increased frequency of dentate granule cells with basal dendrites in the hippocampal formation of schizophrenics
-
DOI 10.1016/S0925-4927(02)00122-1, PII S0925492702001221
-
Lauer M, Beckmann H, Senitz D. 2003. Increased frequency of dentate granule cells with basal dendrites in the hippocampal formation of schizophrenics. Psychiatry Res. 122:89-97 (Pubitemid 36506476)
-
(2003)
Psychiatry Research - Neuroimaging
, vol.122
, Issue.2
, pp. 89-97
-
-
Lauer, M.1
Beckmann, H.2
Senitz, D.3
-
124
-
-
0025952455
-
Recent advances in the phencyclidine model of schizophrenia
-
Javitt DC, Zukin SR. 1991. Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry 148:1301-8
-
(1991)
Am. J. Psychiatry
, vol.148
, pp. 1301-8
-
-
Javitt, D.C.1
Zukin, S.R.2
-
125
-
-
0031979134
-
Schizophrenia and glutamatergic transmission
-
Tamminga CA. 1998. Schizophrenia and glutamatergic transmission. Crit. Rev. Neurobiol. 12:21-36 (Pubitemid 28177262)
-
(1998)
Critical Reviews in Neurobiology
, vol.12
, Issue.1-2
, pp. 21-36
-
-
Tamminga, C.A.1
-
126
-
-
33749074397
-
Glutamate and schizophrenia: Beyond the dopamine hypothesis
-
Coyle JT. 2006. Glutamate and schizophrenia: beyond the dopamine hypothesis. Cell. Mol. Neurobiol. 26:365-84
-
(2006)
Cell. Mol. Neurobiol.
, vol.26
, pp. 365-84
-
-
Coyle, J.T.1
-
127
-
-
0033564390
-
Association of storage and processing functions in the dorsolateral prefrontal cortex of the nonhuman primate
-
Levy R, Goldman-Rakic PS. 1999. Association of storage and processing functions in the dorsolateral prefrontal cortex of the nonhuman primate. J. Neurosci. 19:5149-58 (Pubitemid 29270150)
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.12
, pp. 5149-5158
-
-
Levy, R.1
Goldman-Rakic, P.S.2
-
128
-
-
0001010603
-
Neurocognitive deficits in schizophrenia
-
ed. SR Hirsch, DR Weinberger Oxford, UK: Blackwell Sci. Ltd.
-
Goldberg TE, Gold JM. 1995. Neurocognitive deficits in schizophrenia. In Schizophrenia, ed. SR Hirsch, DR Weinberger, pp. 142-62. Oxford, UK: Blackwell Sci. Ltd.
-
(1995)
Schizophrenia
, pp. 142-62
-
-
Goldberg, T.E.1
Gold, J.M.2
-
129
-
-
7544229805
-
Cognitive deficits as treatment targets in schizophrenia
-
DOI 10.1016/j.schres.2004.09.008, PII S0920996404003433
-
Gold JM. 2004. Cognitive deficits as treatment targets in schizophrenia. Schizophr. Res. 72:21-28 (Pubitemid 39452902)
-
(2004)
Schizophrenia Research
, vol.72
, Issue.1
, pp. 21-28
-
-
Gold, J.M.1
-
130
-
-
0028948389
-
Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics
-
Akbarian S, Kim JJ, Potkin SG, Hagman JO, Tafazzoli A, et al. 1995. Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch. Gen. Psychiatry 52:258-66
-
(1995)
Arch. Gen. Psychiatry
, vol.52
, pp. 258-66
-
-
Akbarian, S.1
Kim, J.J.2
Potkin, S.G.3
Hagman, J.O.4
Tafazzoli, A.5
-
131
-
-
0034850158
-
Lamina-specific deficits in parvalbumin-immunoreactive varicosities in the prefrontal cortex of subjects with schizophrenia: Evidence for fewer projections from the thalamus
-
DOI 10.1176/appi.ajp.158.9.1411
-
Lewis DA, Cruz DA, Melchitzky DS, Pierri JN. 2001. Lamina-specific deficits in parvalbumin-immunoreactive varicosities in the prefrontal cortex of subjects with schizophrenia: evidence for fewer projections from the thalamus. Am. J. Psychiatry 158:1411-22 (Pubitemid 32847239)
-
(2001)
American Journal of Psychiatry
, vol.158
, Issue.9
, pp. 1411-1422
-
-
Lewis, D.A.1
Cruz, D.A.2
Melchitzky, D.S.3
Pierri, J.N.4
-
132
-
-
0035007327
-
GABAergic interneurons: Implications for understanding schizophrenia and bipolar disorder
-
DOI 10.1016/S0893-133X(01)00225-1, PII S0893133X01002251
-
Benes FM, Berretta S. 2001. GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology 25:1-27 (Pubitemid 32493819)
-
(2001)
Neuropsychopharmacology
, vol.25
, Issue.1
, pp. 1-27
-
-
Benes, F.M.1
Berretta, S.2
-
133
-
-
21344438862
-
GABAergic dysfunction in schizophrenia: New treatment strategies on the horizon
-
DOI 10.1007/s00213-005-2212-8
-
Guidotti A, Auta J, Davis JM, Dong E, Grayson DR, et al. 2005. GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology 180:191-205 (Pubitemid 40909664)
-
(2005)
Psychopharmacology
, vol.180
, Issue.2
, pp. 191-205
-
-
Guidotti, A.1
Auta, J.2
Davis, J.M.3
Dong, E.4
Grayson, D.R.5
Veldic, M.6
Zhang, X.7
Costa, E.8
-
134
-
-
30844456191
-
A receptor subtype functions
-
DOI 10.1016/j.coph.2005.10.003, PII S1471489205001864
-
Rudolph U, Mohler H. 2006. GABA-based therapeutic approaches: GABAA receptor subtype functions. Curr. Opin. Pharmacol. 6:18-23 (Pubitemid 43103815)
-
(2006)
Current Opinion in Pharmacology
, vol.6
, Issue.SPEC. ISS. 1
, pp. 18-23
-
-
Rudolph, U.1
Mohler, H.2
-
135
-
-
0023600006
-
Clinical genetics as clues to the 'real' genetics of schizophrenia
-
Gottesman II, McGuffin P, Farmer AE. 1987. Clinical genetics as clues to the "real" genetics of schizophrenia (a decade of modest gains while playing for time). Schizophr. Bull. 13:23-47 (Pubitemid 18037636)
-
(1987)
Schizophrenia Bulletin
, vol.13
, Issue.1
, pp. 23-47
-
-
Gottesman, I.I.1
McGuffin, P.2
Farmer, A.E.3
-
137
-
-
0033614952
-
Risk factors for schizophrenia
-
McGuffin P, Gottesman II, Swerdlow RH, Binder D, Parker WD, et al. 1999. Risk factors for schizophrenia. N. Engl. J. Med. 341:370-72
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 370-72
-
-
McGuffin, P.1
Gottesman, I.I.2
Swerdlow, R.H.3
Binder, D.4
Parker, W.D.5
-
138
-
-
33644753148
-
Psychiatric endophenotypes and the development of valid animal models
-
DOI 10.1111/j.1601-183X.2005.00186.x
-
Gould TD, Gottesman II. 2006. Psychiatric endophenotypes and the development of valid animal models. Genes Brain Behav. 5:113-19 (Pubitemid 43344963)
-
(2006)
Genes, Brain and Behavior
, vol.5
, Issue.2
, pp. 113-119
-
-
Gould, T.D.1
Gottesman, I.I.2
-
139
-
-
0038823525
-
The endophenotype concept in psychiatry: Etymology and strategic intentions
-
DOI 10.1176/appi.ajp.160.4.636
-
Gottesman II, Gould T. 2003. The endophenotype concept in psychiatry: etymology and strategic intentions. Am. J. Psychiatry 160:636-45 (Pubitemid 41079594)
-
(2003)
American Journal of Psychiatry
, vol.160
, Issue.4
, pp. 636-645
-
-
Gottesman, I.I.1
Gould, T.D.2
-
140
-
-
21844480644
-
The use of neurophysiological endophenotypes to understand the genetic basis of schizophrenia
-
Braff DL, Light GA. 2005. The use of neurophysiological endophenotypes to understand the genetic basis of schizophrenia. Dialogues Clin. Neurosci. 7:125-35 (Pubitemid 40961532)
-
(2005)
Dialogues in Clinical Neuroscience
, vol.7
, Issue.2
, pp. 125-135
-
-
Braff, D.L.1
Light, G.A.2
-
141
-
-
33845870419
-
Deconstructing schizophrenia: An overview of the use of endophenotypes in order to understand a complex disorder
-
DOI 10.1093/schbul/sbl049
-
Braff DL, Freedman R, Schork NJ, Gottesman II. 2007. Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr. Bull. 33:21-32 (Pubitemid 46026257)
-
(2007)
Schizophrenia Bulletin
, vol.33
, Issue.1
, pp. 21-32
-
-
Braff, D.L.1
Freedman, R.2
Schork, N.J.3
Gottesman, I.I.4
-
142
-
-
33845886955
-
Endophenotypic studies in schizophrenia: Promise and challenges
-
DOI 10.1093/schbul/sbl062
-
Thaker GK. 2007. Endophenotypic studies in schizophrenia: promise and challenges. Schizophr. Bull. 33:1-2 (Pubitemid 46026252)
-
(2007)
Schizophrenia Bulletin
, vol.33
, Issue.1
, pp. 1-2
-
-
Thaker, G.K.1
-
143
-
-
77950690252
-
Genetics and intermediate phenotypes of the schizophrenia-bipolar disorder boundary
-
Ivleva EI, Morris DW, Moates AF, Suppes T, Thaker GK, Tamminga CA. 2010. Genetics and intermediate phenotypes of the schizophrenia-bipolar disorder boundary. Neurosci. Biobehav. Rev. 34:897-921
-
(2010)
Neurosci. Biobehav. Rev.
, vol.34
, pp. 897-921
-
-
Ivleva, E.I.1
Morris, D.W.2
Moates, A.F.3
Suppes, T.4
Thaker, G.K.5
Tamminga, C.A.6
-
144
-
-
79961129809
-
Extended psychosis phenotype-yes: Single continuum-unlikely
-
Kaymaz N, van Os J. 2010. Extended psychosis phenotype-yes: single continuum-unlikely. Psychol. Med. 18:1-4
-
(2010)
Psychol. Med.
, vol.18
, pp. 1-4
-
-
Kaymaz, N.1
Van Os, J.2
-
145
-
-
0013375948
-
Neuregulin 1 and Susceptibility to Schizophrenia
-
Stefansson H, Sigurdsson E, Steinthorsdottir V, Bjornsdottir S, Sigmundsson T, et al. 2002. Neuregulin 1 and susceptibility to schizophrenia. Am. J. Hum. Genet. 71:877-92 (Pubitemid 135750519)
-
(2002)
American Journal of Human Genetics
, vol.71
, Issue.4
, pp. 877-892
-
-
Stefansson, H.1
Sigurdsson, E.2
Steinthorsdottir, V.3
Bjornsdottir, S.4
Sigmundsson, T.5
Ghosh, S.6
Brynjolfsson, J.7
Gunnarsdottir, S.8
Ivarsson, O.9
Chou, T.T.10
Hjaltason, O.11
Birgisdottir, B.12
Jonsson, H.13
Gudnadottir, V.G.14
Gudmundsdottir, E.15
Bjornsson, A.16
Ingvarsson, B.17
Ingason, A.18
Sigfusson, S.19
Hardardottir, H.20
Harvey, R.P.21
Lai, D.22
Zhou, M.23
Brunner, D.24
Mutel, V.25
Gonzalo, A.26
Lemke, G.27
Sainz, J.28
Johannesson, G.29
Andresson, T.30
Gudbjartsson, D.31
Manolescu, A.32
Frigge, M.L.33
Gurney, M.E.34
Kong, A.35
Gulcher, J.R.36
Petursson, H.37
Stefansson, K.38
more..
-
146
-
-
0042202625
-
Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia
-
DOI 10.1073/pnas.1432926100
-
Miyakawa T, Leiter LM, Gerber DJ, Gainetdinov RR, Sotnikova TD,et al. 2003. Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia. Proc. Natl. Acad. Sci. USA 100:8987-92 (Pubitemid 36899210)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.15
, pp. 8987-8992
-
-
Miyakawa, T.1
Leiter, L.M.2
Gerber, D.J.3
Gainetdinov, R.R.4
Sotnikova, T.D.5
Zeng, H.6
Caron, M.G.7
Tonegawa, S.8
-
147
-
-
33745221854
-
A review of Disrupted-In-Schizophrenia-1 (DISC1): Neurodevelopment, cognition, and mental conditions
-
Ishizuka K, Paek M, Kamiya A, Sawa A. 2006. A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions. Biol. Psychiatry 59:1189-97
-
(2006)
Biol. Psychiatry
, vol.59
, pp. 1189-97
-
-
Ishizuka, K.1
Paek, M.2
Kamiya, A.3
Sawa, A.4
-
148
-
-
33745712343
-
The genetics and biology of DISC1-an emerging role in psychosis and cognition
-
Porteous DJ, Thomson P, Brandon NJ, Millar JK. 2006. The genetics and biology of DISC1-an emerging role in psychosis and cognition. Biol. Psychiatry 60:123-31
-
(2006)
Biol. Psychiatry
, vol.60
, pp. 123-31
-
-
Porteous, D.J.1
Thomson, P.2
Brandon, N.J.3
Millar, J.K.4
-
149
-
-
17744391567
-
Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia
-
DOI 10.1038/sj.mp.4000784
-
Millar JK, Christie S, Anderson S, Lawson D, Hsiao-Wei LD, et al. 2001. Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia. Mol. Psychiatry 6:173-78 (Pubitemid 32187867)
-
(2001)
Molecular Psychiatry
, vol.6
, Issue.2
, pp. 173-178
-
-
Millar, J.K.1
Christie, S.2
Anderson, S.3
Lawson, D.4
Loh, D.H.-W.5
Devon, R.S.6
Arveiler, B.7
Muir, W.J.8
Blackwood, D.H.R.9
Porteous, D.J.10
-
150
-
-
8744231685
-
Replication of 1q42 linkage in Finnish schizophrenia pedigrees
-
DOI 10.1038/sj.mp.4001536
-
Ekelund J, Hennah W, Hiekkalinna T, Parker A, Meyer J, et al. 2004. Replication of 1q42 linkage in Finnish schizophrenia pedigrees. Mol. Psychiatry 9:1037-41 (Pubitemid 39524292)
-
(2004)
Molecular Psychiatry
, vol.9
, Issue.11
, pp. 1037-1041
-
-
Ekelund, J.1
Hennah, W.2
Hiekkalinna, T.3
Parker, A.4
Meyer, J.5
Lonnqvist, J.6
Peltonen, L.7
-
151
-
-
6344255274
-
Disrupted in Schizophrenia 1 (DISC1): Association with Schizophrenia, schizoaffective disorder, and bipolar disorder
-
DOI 10.1086/425586
-
Hodgkinson CA, Goldman D, Jaeger J, Persaud S, Kane JM, et al. 2004. Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder. Am. J. Hum. Genet. 75:862-72 (Pubitemid 39390493)
-
(2004)
American Journal of Human Genetics
, vol.75
, Issue.5
, pp. 862-872
-
-
Hodgkinson, C.A.1
Goldman, D.2
Jaeger, J.3
Persaud, S.4
Kane, J.M.5
Lipsky, R.H.6
Malhotra, A.K.7
-
152
-
-
11244302487
-
A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42
-
DOI 10.1038/sj.mp.4001544
-
Macgregor S, Visscher PM, Knott SA, Thomson P, Porteous DJ, et al. 2004. A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42. Mol. Psychiatry 9:1083-90 (Pubitemid 40065453)
-
(2004)
Molecular Psychiatry
, vol.9
, Issue.12
, pp. 1083-1090
-
-
Macgregor, S.1
Visscher, P.M.2
Knott, S.A.3
Thomson, P.4
Porteous, D.J.5
Millar, J.K.6
Devon, R.S.7
Blackwood, D.8
Muir, W.J.9
-
153
-
-
25844501532
-
Genomewide linkage scan in schizoaffective disorder: Significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13
-
DOI 10.1001/archpsyc.62.10.1081
-
Hamshere ML, Bennett P, Williams N, Segurado R, Cardno A, et al. 2005. Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Arch. Gen. Psychiatry 62:1081-88 (Pubitemid 41396933)
-
(2005)
Archives of General Psychiatry
, vol.62
, Issue.10
, pp. 1081-1088
-
-
Hamshere, M.L.1
Bennett, P.2
Williams, N.3
Segurado, R.4
Cardno, A.5
Norton, N.6
Lambert, D.7
Williams, H.8
Kirov, G.9
Corvin, A.10
Holmans, P.11
Jones, L.12
Jones, I.13
Gill, M.14
O'Donovan, M.C.15
Owen, M.J.16
Craddock, N.17
-
154
-
-
21844435448
-
Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population
-
DOI 10.1038/sj.mp.4001669
-
Thomson PA, Wray NR, Millar JK, Evans KL, Hellard SL, et al. 2005. Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Mol. Psychiatry 10:657-68 (Pubitemid 40961736)
-
(2005)
Molecular Psychiatry
, vol.10
, Issue.7
, pp. 657-668
-
-
Thomson, P.A.1
Wray, N.R.2
Millar, J.K.3
Evans, K.L.4
Le Hellard, S.5
Condie, A.6
Muir, W.J.7
Blackwood, D.H.R.8
Porteous, D.J.9
-
155
-
-
32244433189
-
Genetic association between schizophrenia and the DISC1 gene in the Scottish population
-
DOI 10.1002/ajmg.b.30274
-
Zhang F, Sarginson J, Crombie C, Walker N, St Clair D, Shaw D. 2006. Genetic association between schizophrenia and the DISC1 gene in the Scottish population. Am. J. Med. Genet. B Neuropsychiatr. Genet. 141B:155-59 (Pubitemid 43214791)
-
(2006)
American Journal of Medical Genetics - Neuropsychiatric Genetics
, vol.B
, Issue.2
, pp. 155-159
-
-
Zhang, F.1
Sarginson, J.2
Crombie, C.3
Walker, N.4
St. Clair, D.5
Shaw, D.6
-
156
-
-
33846819016
-
Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population
-
DOI 10.1016/j.jpsychires.2006.01.001, PII S0022395606000136
-
Chen QY, Chen Q, Feng GY, Lindpaintner K, Wang LJ, et al. 2007. Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population. J. Psychiatr. Res. 41:428-34 (Pubitemid 46201948)
-
(2007)
Journal of Psychiatric Research
, vol.41
, Issue.5
, pp. 428-434
-
-
Chen, Q.-Y.1
Chen, Q.2
Feng, G.-Y.3
Lindpaintner, K.4
Wang, L.-J.5
Chen, Z.-X.6
Gao, Z.-S.7
Tang, J.-S.8
Huang, G.9
He, L.10
-
157
-
-
34247465605
-
Positive association of the Disrupted-in-schizophrenia-1 gene (DISC1) with schizophrenia in the Chinese Han Population
-
DOI 10.1002/ajmg.b.30322
-
Qu M, Tang F, Yue W, Ruan Y, Lu T, et al. 2007. Positive association of the Disrupted-in-Schizophrenia-1 gene (DISC1) with schizophrenia in the Chinese Han population. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B:266-70 (Pubitemid 46646662)
-
(2007)
American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
, vol.144
, Issue.3
, pp. 266-270
-
-
Qu, M.1
Tang, F.2
Yue, W.3
Ruan, Y.4
Lu, T.5
Liu, Z.6
Zhang, H.7
Han, Y.8
Zhang, D.9
Wang, F.10
Zhang, D.11
-
158
-
-
28544453286
-
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development
-
Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, et al. 2005. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat. Cell Biol. 7:1167-78
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 1167-78
-
-
Kamiya, A.1
Kubo, K.2
Tomoda, T.3
Takaki, M.4
Youn, R.5
-
159
-
-
0345530985
-
Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects
-
DOI 10.1093/hmg/ddg341
-
Hennah W, Varilo T, Kestila M, Paunio T, Arajarvi R, et al. 2003. Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects. Hum. Mol. Genet. 12:3151-59 (Pubitemid 37508886)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.23
, pp. 3151-3159
-
-
Hennah, W.1
Varilo, T.2
Kestila, M.3
Paunio, T.4
Arajarvi, R.5
Haukka, J.6
Parker, A.7
Martin, R.8
Levitzky, S.9
Partonen, T.10
Meyer, J.11
Lonnqvist, J.12
Peltonen, L.13
Ekelund, J.14
-
160
-
-
20844463251
-
Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia
-
DOI 10.1073/pnas.0500515102
-
Callicott JH, Straub RE, Pezawas L, Egan MF, Mattay VS, et al. 2005. Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc. Natl. Acad. Sci. USA 102:8627-32 (Pubitemid 40862786)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.24
, pp. 8627-8632
-
-
Callicott, J.H.1
Straub, R.E.2
Pezawas, L.3
Egan, M.F.4
Mattay, V.S.5
Hariri, A.R.6
Verchinski, B.A.7
Meyer-Lindenberg, A.8
Balkissoon, R.9
Kolachana, B.10
Goldberg, T.E.11
Weinberger, D.R.12
-
161
-
-
33745616542
-
Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia
-
DOI 10.1093/hmg/ddl122
-
Li D, Collier DA, He L. 2006. Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia. Hum. Mol. Genet. 15:1995-2002 (Pubitemid 43983273)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.12
, pp. 1995-2002
-
-
Li, D.1
Collier, D.A.2
He, L.3
-
163
-
-
46249104490
-
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: The SzGene database
-
DOI 10.1038/ng.171, PII NG171
-
Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, et al. 2008. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat. Genet. 40:827-34 (Pubitemid 351913655)
-
(2008)
Nature Genetics
, vol.40
, Issue.7
, pp. 827-834
-
-
Allen, N.C.1
Bagade, S.2
McQueen, M.B.3
Ioannidis, J.P.A.4
Kavvoura, F.K.5
Khoury, M.J.6
Tanzi, R.E.7
Bertram, L.8
-
164
-
-
43949084738
-
Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
-
DOI 10.1038/nrn2392, PII NRN2392
-
Mei L, Xiong WC. 2008. Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. Nat. Rev. Neurosci. 9:437-52 (Pubitemid 351704944)
-
(2008)
Nature Reviews Neuroscience
, vol.9
, Issue.6
, pp. 437-452
-
-
Mei, L.1
Xiong, W.-C.2
-
165
-
-
63149158010
-
Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system
-
Barros CS, Calabrese B, Chamero P, Roberts AJ, Korzus E, et al. 2009. Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system. Proc. Natl. Acad. Sci. USA 106:4507-12
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 4507-12
-
-
Barros, C.S.1
Calabrese, B.2
Chamero, P.3
Roberts, A.J.4
Korzus, E.5
-
166
-
-
37149001493
-
Disturbed structural connectivity in schizophrenia - Primary factor in pathology or epiphenomenon?
-
DOI 10.1093/schbul/sbm034
-
Konrad A, Winterer G. 2008. Disturbed structural connectivity in schizophrenia-primary factor in pathology or epiphenomenon? Schizophr. Bull. 34:72-92 (Pubitemid 350262274)
-
(2008)
Schizophrenia Bulletin
, vol.34
, Issue.1
, pp. 72-92
-
-
Konrad, A.1
Winterer, G.2
-
167
-
-
33845260095
-
A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms
-
DOI 10.1038/nn1795, PII NN1795
-
Hall J, Whalley HC, Job DE, Baig BJ, McIntosh AM, et al. 2006. A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms. Nat. Neurosci. 9:1477-78 (Pubitemid 44862654)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.12
, pp. 1477-1478
-
-
Hall, J.1
Whalley, H.C.2
Job, D.E.3
Baig, B.J.4
McIntosh, A.M.5
Evans, K.L.6
Thomson, P.A.7
Porteous, D.J.8
Cunningham-Owens, D.G.9
Johnstone, E.C.10
Lawrie, S.M.11
-
168
-
-
66949163644
-
Genetic variation in the schizophrenia-risk gene neuregulin 1 correlates with brain activation and impaired speech production in a verbal fluency task in healthy individuals
-
Kircher T, Krug A, Markov V, Whitney C, Krach S, et al. 2009. Genetic variation in the schizophrenia-risk gene neuregulin 1 correlates with brain activation and impaired speech production in a verbal fluency task in healthy individuals. Hum. Brain Mapp. 30:3406-16
-
(2009)
Hum. Brain Mapp.
, vol.30
, pp. 3406-16
-
-
Kircher, T.1
Krug, A.2
Markov, V.3
Whitney, C.4
Krach, S.5
-
169
-
-
49049113745
-
Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components
-
Chen YJ, Johnson MA, Lieberman MD, Goodchild RE, Schobel S, et al. 2008. Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components. J. Neurosci. 28:6872-83
-
(2008)
J. Neurosci.
, vol.28
, pp. 6872-83
-
-
Chen, Y.J.1
Johnson, M.A.2
Lieberman, M.D.3
Goodchild, R.E.4
Schobel, S.5
-
170
-
-
34249888202
-
Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1
-
DOI 10.1016/j.neuroscience.2007.03.051, PII S0306452207003818
-
O'Tuathaigh CM, Babovic D, O'Sullivan GJ, Clifford JJ, Tighe O, et al. 2007. Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1. Neuroscience 147:18-27 (Pubitemid 46873845)
-
(2007)
Neuroscience
, vol.147
, Issue.1
, pp. 18-27
-
-
O'Tuathaigh, C.M.P.1
Babovic, D.2
O'Sullivan, G.J.3
Clifford, J.J.4
Tighe, O.5
Croke, D.T.6
Harvey, R.7
Waddington, J.L.8
|