Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression

Molecular Psychiatry

Volumn 12, Issue 9, 2007, Pages 854-869

  Straub, R E ^a   Lipska, B K ^a   Egan, M F ^a   Goldberg, T E ^a   Callicott, J H ^a   Mayhew, M B ^a   Vakkalanka, R K ^a   Kolachana, B S ^a   Kleinman, J E ^a   Weinberger, D R ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

COMT; Epistasis; GAD1; GAD67; Schizophrenia

Indexed keywords

4 AMINOBUTYRIC ACID; CATECHOL METHYLTRANSFERASE; GLUTAMATE DECARBOXYLASE 67; MESSENGER RNA; VALINE;

5' UNTRANSLATED REGION; ADULT; ALLELE; ARTICLE; ATTENTION; BRAIN CORTEX; BRAIN FUNCTION; BRAIN TISSUE; COGNITION; CONTROLLED STUDY; DECLARATIVE MEMORY; DNA FLANKING REGION; DOPAMINERGIC SYSTEM; EPISTASIS; FAMILY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENDER; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC EPISTASIS; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; INHIBITION KINETICS; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PHENOTYPE; PHYSIOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; QUANTITATIVE ANALYSIS; SAMPLE; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; WORKING MEMORY;

ADOLESCENT; ADULT; ALLELES; CATECHOL O-METHYLTRANSFERASE; CEREBRAL CORTEX; FAMILY HEALTH; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GLUTAMATE DECARBOXYLASE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LINKAGE DISEQUILIBRIUM; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; OXYGEN; POLYMORPHISM, SINGLE NUCLEOTIDE; SCHIZOPHRENIA; SEX FACTORS;

EID: 34548303921     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/sj.mp.4001988     Document Type: Article

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