Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo

Journal of Molecular and Cellular Cardiology

Volumn 79, Issue , 2015, Pages 1-12

  Zeng, Chunlai ^a   Zhong, Peng ^a   Zhao, Yunjie ^a   Kanchana, Karvannan ^a   Zhang, Yali ^a   Khan, Zia A ^b   Chakrabarti, Subrata ^b   Wu, Lianpin ^a   Wang, Jingying ^a   Liang, Guang ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Cardioprotection; Curcumin; Free fatty acids; Inflammation; Oxidative stress

Indexed keywords

CHOLESTEROL; CURCUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOW DENSITY LIPOPROTEIN; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; TRIACYLGLYCEROL; ANTIINFLAMMATORY AGENT; CARDIOTONIC AGENT; FATTY ACID; PALMITIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL CULTURE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; HEART HYPERTROPHY; HEART INJURY; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIPID DIET; LIPOPROTEIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; RAT; TRANSCRIPTION INITIATION; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BODY WEIGHT; C57BL MOUSE; CARDIOMEGALY; CELL LINE; COMPLICATION; DRUG EFFECTS; FIBROSIS; HEART MUSCLE; METABOLISM; PATHOLOGY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BODY WEIGHT; CARDIOMEGALY; CARDIOTONIC AGENTS; CELL LINE; CURCUMIN; DIET, HIGH-FAT; FATTY ACIDS, NONESTERIFIED; FIBROSIS; MALE; MICE, INBRED C57BL; MYOCARDIUM; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; PALMITATES; RATS; REACTIVE OXYGEN SPECIES;

EID: 84911395766     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2014.10.002     Document Type: Article

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