Antitumor activity of glycyrol via induction of cell cycle arrest, apoptosis and defective autophagy

Food and Chemical Toxicology

Volumn 74, Issue , 2014, Pages 311-319

  Xu, Mei Ying ^a   Kim, Yeong Shik ^a  

^a Seoul National University   (South Korea)

Author keywords

AMPK; Apoptosis; Cell cycle arrest; Defective autophagy; Glycyrol; JNK

Indexed keywords

ADENYLATE KINASE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; GLYCYROL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROCASPASE 9; PROTEIN KINASE B; PROTEIN P21; STRESS ACTIVATED PROTEIN KINASE 1; UNCLASSIFIED DRUG; CASPASE; FLAVONOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL LINE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL DEATH; CELL VIABILITY; COLON CANCER; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; ENZYME ACTIVATION; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GLYCYRRHIZA URALENSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYSOSOME; MALE; MALIGNANT NEOPLASTIC DISEASE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; STOMACH CANCER; TUMOR VOLUME; UPREGULATION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; CELL CYCLE CHECKPOINT; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; DRUG SCREENING; HCT116 CELL LINE; METABOLISM; PHYSIOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; AUTOPHAGY; CASPASES; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELL SURVIVAL; FLAVONOIDS; G1 PHASE; HCT116 CELLS; HUMANS; MALE; MICE; MICE, INBRED BALB C; P38 MITOGEN-ACTIVATED PROTEIN KINASES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84910098212     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2014.10.023     Document Type: Article

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