Withaferin a, a steroidal lactone from withania somnifera, induces mitotic catastrophe and growth arrest in prostate cancer cells

Journal of Natural Products

Volumn 76, Issue 10, 2013, Pages 1909-1915

  Roy, Ram V ^a   Suman, Suman ^a   Das, Trinath P ^a   Luevano, Joe E ^a   Damodaran, Chendil ^a  

^a Paul L Foster School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN 20; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN A2; CYCLIN B1; CYCLIN E; CYCLIN E2; UNCLASSIFIED DRUG; WITHAFERIN A;

ARTICLE; CANCER CELL; CELL CULTURE; CELL CYCLE ARREST; CELL DEATH; CELL FREE SYSTEM; CELL VIABILITY; DOWN REGULATION; ENZYME PHOSPHORYLATION; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; MICROTUBULE ASSEMBLY; MITOSIS INHIBITION; PROSTATE CANCER; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WITHANIA SOMNIFERA;

APOPTOSIS; CDC2 PROTEIN KINASE; CELL CYCLE; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; G2 PHASE; HISTONES; HUMANS; MALE; MITOSIS; MOLECULAR STRUCTURE; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53; WITHANIA; WITHANOLIDES;

EID: 84886846586     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np400441f     Document Type: Article

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