Melatonin modifies cellular stress in the liver of septic mice by reducing reactive oxygen species and increasing the unfolded protein response

Experimental and Molecular Pathology

Volumn 97, Issue 3, 2014, Pages 565-571

  Kleber, Astrid ^a   Kubulus, Darius ^a   Rössler, Daniel ^a   Wolf, Beate ^a   Volk, Thomas ^a   Speer, Thimoteus ^a   Fink, Tobias ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Acute phase response; Melatonin; Reactive oxygen species; Sepsis; Unfolded protein response

Indexed keywords

CASPASE 12; CASPASE 3; CELL ADHESION MOLECULE; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INTERCELLULAR ADHESION MOLECULE 1; MELATONIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NUCLEAR RECEPTOR NUR77; REACTIVE OXYGEN METABOLITE; VASCULAR CELL ADHESION MOLECULE 1; ANTIOXIDANT;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CELL STRESS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTRON SPIN RESONANCE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HORMONAL THERAPY; LIVER; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SEPSIS; UNFOLDED PROTEIN RESPONSE; UPREGULATION; WESTERN BLOTTING; ANIMAL; C3H MOUSE; DISEASE MODEL; DRUG EFFECTS; METABOLISM; PATHOLOGY;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; ELECTRON SPIN RESONANCE SPECTROSCOPY; LIVER; MALE; MELATONIN; MICE; MICE, INBRED C3H; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; SEPSIS; UNFOLDED PROTEIN RESPONSE;

EID: 84909998793     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2014.10.009     Document Type: Article

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