Synergistic hepatotoxicity of N,N-dimethylformamide with carbon tetrachloride in association with endoplasmic reticulum stress

Chemico-Biological Interactions

Volumn 184, Issue 3, 2010, Pages 492-501

  Kim, Tae Hyun ^a   Kim, Young Woo ^a   Shin, Sang Mi ^a   Kim, Choon Won ^b   Yu, Il Je ^c   Kim, Sang Geon ^a  

^a Seoul National University   (South Korea)

^b Hanyang University   (South Korea)

^c Hoseo University   (South Korea)

Author keywords

Carbon tetrachloride; DMF; ER stress; Hepatocyte death; Hepatotoxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; GALACTOSAMINE; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; INITIATION FACTOR 2; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; N,N DIMETHYLFORMAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARACETAMOL; PROTEIN BCL XL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIVISION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER TOXICITY; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; CARBON TETRACHLORIDE; CASPASE 3; EIF-2 KINASE; ENDOPLASMIC RETICULUM; FORMAMIDES; HEAT-SHOCK PROTEINS; LACTATE DEHYDROGENASES; LIVER; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY; TRANSAMINASES;

RATTUS;

EID: 77949917540     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.01.029     Document Type: Article

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