The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells

Molecular Cancer Research

Volumn 12, Issue 4, 2014, Pages 527-538

  Lee, Syng Ook ^a,f   Jin, Un Ho ^a   Kang, Jeong Han ^e   Kim, Sang Bae ^b   Guthrie, Aaron S ^c   Sreevalsan, Sandeep ^d   Lee, Ju Seog ^b   Safe, Stephen ^a,d  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

^d TEXAS A AND M UNIVERSITY   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f Keimyung University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 BIS(3' INDOLYL) 1 (4 HYDROXYPHENYL)METHANE; ACTIVATING TRANSCRIPTION FACTOR 4; ANTIOXIDANT; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INDOLE DERIVATIVE; METHANE; NUCLEAR RECEPTOR NUR77; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; THIOREDOXIN DOMAIN CONTAINING 5; UNCLASSIFIED DRUG; 1,1-BIS(3'-INDOLYL)-1-(4-HYDROXYPHENYL)METHANE; NR4A1 PROTEIN, HUMAN; PHENOL DERIVATIVE; PROTEIN DISULFIDE ISOMERASE; TXNDC5 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; METABOLIC REGULATION; OXIDATIVE STRESS; PANCREAS CANCER; PRIORITY JOURNAL; PROTEOMICS; REGULATORY MECHANISM; RNA INTERFERENCE; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL GROWTH; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; METABOLISM; PANCREAS TUMOR; PATHOLOGY; PHYSIOLOGY; TISSUE MICROARRAY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE;

APOPTOSIS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; INDOLES; MICROSCOPY, ELECTRON, TRANSMISSION; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; OXIDATIVE STRESS; PANCREATIC NEOPLASMS; PHENOLS; PROTEIN DISULFIDE-ISOMERASES; REACTIVE OXYGEN SPECIES; TISSUE ARRAY ANALYSIS; TRANSFECTION;

EID: 84899478610     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-13-0567     Document Type: Article

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