Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: Regulation of pro-/anti-inflammatory cytokine network, protection against oxidative damage and anti-apoptotic effects

Journal of Pineal Research

Volumn 39, Issue 4, 2005, Pages 400-408

  Carrillo Vico, Antonio ^a   Lardone, Patricia J ^a   Naji, Latifa ^a   Fernández Santos, José M ^a   Martín Lacave, Inés ^a   Guerrero, Juan M ^a   Calvo, Juan R ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Apoptosis; LPS; Melatonin; Nitric oxide; Oxidative damage; Pro anti inflammatory cytokines; Septic shock

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; MELATONIN; NITRATE; NITRIC OXIDE; NITRITE; NITROGEN RADICAL; OXYGEN RADICAL; RADICAL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; INTERLEUKIN DERIVATIVE;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HORMONE ACTION; IMMUNOMODULATION; INJECTION SITE; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PLEIOTROPY; SEPTIC SHOCK; SURVIVAL RATE; ANIMAL; BIOSYNTHESIS; BRAIN; DISEASE MODEL; DRUG EFFECT; LIVER; METABOLISM; PATHOPHYSIOLOGY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BRAIN; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; INTERFERON TYPE II; INTERLEUKINS; LIPID PEROXIDATION; LIVER; MELATONIN; MICE; NITRIC OXIDE; SHOCK, SEPTIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 27744447352     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2005.00265.x     Document Type: Article

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