New insights about enzyme evolution from large scale studies of sequence and structure relationships

Journal of Biological Chemistry

Volumn 289, Issue 44, 2014, Pages 30221-30228

  Brown, Shoshana D ^a   Babbitt, Patricia C ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

ACTIVE SITE; ENZYME EVOLUTIONS; ENZYME SUPERFAMILIES; LARGE-SCALE STUDIES; STRUCTURE-FUNCTION RELATIONSHIP; SUBSTRATE SPECIFICITY;

ENZYMES;

ARYLDIALKYLPHOSPHATASE; ENZYME; ESTERASE; GLUCONOLACTONASE; OXIDOREDUCTASE; PHOSPHOTRIESTERASE; UNSPECIFIC MONOOXYGENASE;

AMINO ACID SEQUENCE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; HUMAN; MOLECULAR EVOLUTION; PHYLOGENETIC TREE; PHYLOGENY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; BIOCATALYSIS; CHEMISTRY; GENETICS; OXIDATION REDUCTION REACTION; SEQUENCE ANALYSIS;

BIOCATALYSIS; CATALYTIC DOMAIN; ENZYMES; EVOLUTION, MOLECULAR; HUMANS; OXIDATION-REDUCTION; PHYLOGENY; SEQUENCE ANALYSIS, PROTEIN;

EID: 84908587486     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.R114.569350     Document Type: Review

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