-
1
-
-
34250157784
-
Caspase-3 activation in astrocytes following postnatal excitotoxic damage correlates with cytoskeletal remodelling but not with cell death or proliferation
-
Acarin L., Villapol S., Faiz M., Rohn T.T., Castellano B., Gonzalez B. Caspase-3 activation in astrocytes following postnatal excitotoxic damage correlates with cytoskeletal remodelling but not with cell death or proliferation. Glia 2007, 55:954-965.
-
(2007)
Glia
, vol.55
, pp. 954-965
-
-
Acarin, L.1
Villapol, S.2
Faiz, M.3
Rohn, T.T.4
Castellano, B.5
Gonzalez, B.6
-
2
-
-
84859420475
-
Caspase activation contributes to astrogliosis
-
Aras R., Barron A.M., Pike C.J. Caspase activation contributes to astrogliosis. Brain Res 2012, 1450:102-115.
-
(2012)
Brain Res
, vol.1450
, pp. 102-115
-
-
Aras, R.1
Barron, A.M.2
Pike, C.J.3
-
3
-
-
36348973410
-
Increased expression of the lysosomal protease cathepsin S in hippocampal microglia following kainite-induced seizures
-
Akahoshi N., Murashima Y.L., Himi T., Ishizaki Y., Ishii I. Increased expression of the lysosomal protease cathepsin S in hippocampal microglia following kainite-induced seizures. Neurosci Lett 2007, 429:136-141.
-
(2007)
Neurosci Lett
, vol.429
, pp. 136-141
-
-
Akahoshi, N.1
Murashima, Y.L.2
Himi, T.3
Ishizaki, Y.4
Ishii, I.5
-
4
-
-
73549105909
-
Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann Pick type C-deficient mice
-
Amritraj A., Peake K., Kodam A., Salio C., Merighi A., Vance J., Kar S. Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann Pick type C-deficient mice. Am J Pathol 2009, 175:2540-2556.
-
(2009)
Am J Pathol
, vol.175
, pp. 2540-2556
-
-
Amritraj, A.1
Peake, K.2
Kodam, A.3
Salio, C.4
Merighi, A.5
Vance, J.6
Kar, S.7
-
5
-
-
84873290004
-
Role of cathepsin D in U18666A-induced neuronal cell death: potential implication in Niemann Pick Type C disease pathogenesis
-
Amritraj A., Wang Y., Revett T.J., Vergote D., Westaway D., Kar S. Role of cathepsin D in U18666A-induced neuronal cell death: potential implication in Niemann Pick Type C disease pathogenesis. J Biol Chem 2013, 288:3136-3152.
-
(2013)
J Biol Chem
, vol.288
, pp. 3136-3152
-
-
Amritraj, A.1
Wang, Y.2
Revett, T.J.3
Vergote, D.4
Westaway, D.5
Kar, S.6
-
6
-
-
12944316603
-
ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation
-
Barlow C., Ribaut-Barassin C., Zwingman T.A., Pope A.J., Brown K.D., Owens J.W., Larson D., Harrington E.A., Haeberle A.M., Mariani J., Eckhaus M., Herrup K., Bailly Y., Wynshaw-Boris A. ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation. Proc Natl Acad Sci U S A 2000, 97:871-876.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 871-876
-
-
Barlow, C.1
Ribaut-Barassin, C.2
Zwingman, T.A.3
Pope, A.J.4
Brown, K.D.5
Owens, J.W.6
Larson, D.7
Harrington, E.A.8
Haeberle, A.M.9
Mariani, J.10
Eckhaus, M.11
Herrup, K.12
Bailly, Y.13
Wynshaw-Boris, A.14
-
7
-
-
0021921141
-
Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy
-
Ben-Ari Y. Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. Neuroscience 1985, 14:375-403.
-
(1985)
Neuroscience
, vol.14
, pp. 375-403
-
-
Ben-Ari, Y.1
-
8
-
-
0019472821
-
Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy
-
Ben-Ari Y., Tremblay E., Riche D., Ghilini G., Naquet R. Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy. Neuroscience 1981, 6:1361-1391.
-
(1981)
Neuroscience
, vol.6
, pp. 1361-1391
-
-
Ben-Ari, Y.1
Tremblay, E.2
Riche, D.3
Ghilini, G.4
Naquet, R.5
-
9
-
-
0034333266
-
Kainate, a double agent that generates seizures: two decades of progress
-
Ben-Ari Y., Cossart R. Kainate, a double agent that generates seizures: two decades of progress. Trends Neurosci 2000, 23:580-587.
-
(2000)
Trends Neurosci
, vol.23
, pp. 580-587
-
-
Ben-Ari, Y.1
Cossart, R.2
-
10
-
-
0037989761
-
Lysosomal activation is a compensatory response against protein accumulation and associated synaptogenesis - an approach for slowing Alzheimer's disease ?
-
Bendiske J., Bahr B.A. Lysosomal activation is a compensatory response against protein accumulation and associated synaptogenesis - an approach for slowing Alzheimer's disease ?. J Neuropathol Exp Neurol 2003, 62:451-463.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 451-463
-
-
Bendiske, J.1
Bahr, B.A.2
-
11
-
-
50649106648
-
Cathepsin D - many functions of one aspartic protease
-
Benes P., Vetvicka V., Fusek M. Cathepsin D - many functions of one aspartic protease. Crit Rev Oncol Hematol 2008, 68:12-28.
-
(2008)
Crit Rev Oncol Hematol
, vol.68
, pp. 12-28
-
-
Benes, P.1
Vetvicka, V.2
Fusek, M.3
-
12
-
-
0036454650
-
Neuronal apoptosis after brief and prolonged seizures
-
Bengzon J., Mohapel P., Ekdahl C.T., Lindvall O. Neuronal apoptosis after brief and prolonged seizures. Prog Brain Res 2002, 135:111-119.
-
(2002)
Prog Brain Res
, vol.135
, pp. 111-119
-
-
Bengzon, J.1
Mohapel, P.2
Ekdahl, C.T.3
Lindvall, O.4
-
13
-
-
0034960228
-
CXCR4-activated astrocytes glutamate via TNFα: amplification by microglia triggers neurotoxicity
-
Bezzi P., Domercq M., Brambilla L., Galli R., Schols D., De Clercq E., Vescovi A., Bagetta G., Kollias G., Meldolesi J., Volterra A. CXCR4-activated astrocytes glutamate via TNFα: amplification by microglia triggers neurotoxicity. Nat Neurosci 2001, 4:702-710.
-
(2001)
Nat Neurosci
, vol.4
, pp. 702-710
-
-
Bezzi, P.1
Domercq, M.2
Brambilla, L.3
Galli, R.4
Schols, D.5
De Clercq, E.6
Vescovi, A.7
Bagetta, G.8
Kollias, G.9
Meldolesi, J.10
Volterra, A.11
-
14
-
-
0032192550
-
Neuropharmacology of AMPA and kainite receptors
-
Bleakman D., Lodge D. Neuropharmacology of AMPA and kainite receptors. Neuropharmacology 1998, 37:1187-1204.
-
(1998)
Neuropharmacology
, vol.37
, pp. 1187-1204
-
-
Bleakman, D.1
Lodge, D.2
-
15
-
-
54949137644
-
Lysosomal membrane permeabilization in cell death
-
Boya P., Kroemer G. Lysosomal membrane permeabilization in cell death. Oncogene 2008, 27:6434-6451.
-
(2008)
Oncogene
, vol.27
, pp. 6434-6451
-
-
Boya, P.1
Kroemer, G.2
-
17
-
-
77955085839
-
Inflammatory neurodegeneration and mechanisms of microglial killing of neurons
-
Brown G.C., Neher J.J. Inflammatory neurodegeneration and mechanisms of microglial killing of neurons. Mol Neurobiol 2010, 41:242-247.
-
(2010)
Mol Neurobiol
, vol.41
, pp. 242-247
-
-
Brown, G.C.1
Neher, J.J.2
-
18
-
-
0034948738
-
The autophagosomal-lysosomal compartment in programmed cell death
-
Bursch W. The autophagosomal-lysosomal compartment in programmed cell death. Cell Death Differ 2001, 8:569-581.
-
(2001)
Cell Death Differ
, vol.8
, pp. 569-581
-
-
Bursch, W.1
-
19
-
-
79958694159
-
Protective effects of positive lysosomal modulation in Alzheimer's disease transgenic mouse models
-
Butler D., Hwang J., Estick C., Nishiyama A., Kumar S.S., Baveghems C., Young-Oxendine H.B., Wisniewski M.L., Charalambides A., Bahr B.A. Protective effects of positive lysosomal modulation in Alzheimer's disease transgenic mouse models. PLoS One 2011, 6:e20501.
-
(2011)
PLoS One
, vol.6
, pp. e20501
-
-
Butler, D.1
Hwang, J.2
Estick, C.3
Nishiyama, A.4
Kumar, S.S.5
Baveghems, C.6
Young-Oxendine, H.B.7
Wisniewski, M.L.8
Charalambides, A.9
Bahr, B.A.10
-
20
-
-
0035020420
-
Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis
-
Byun Y., Chen F., Chang R., Trivedi M., Green K.J., Cryns V.L. Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis. Cell Death Differ 2001, 8:443-450.
-
(2001)
Cell Death Differ
, vol.8
, pp. 443-450
-
-
Byun, Y.1
Chen, F.2
Chang, R.3
Trivedi, M.4
Green, K.J.5
Cryns, V.L.6
-
21
-
-
78650951398
-
Cathepsin D plays a crucial role in the trimethyltin-induced hippocampal neurodegeneration process
-
Ceccariglia S., D'Altocolle A., Del Fa A., Pizzolante F., Caccia E., Michetti F., Gangitano C. Cathepsin D plays a crucial role in the trimethyltin-induced hippocampal neurodegeneration process. Neuroscience 2011, 174:160-170.
-
(2011)
Neuroscience
, vol.174
, pp. 160-170
-
-
Ceccariglia, S.1
D'Altocolle, A.2
Del Fa, A.3
Pizzolante, F.4
Caccia, E.5
Michetti, F.6
Gangitano, C.7
-
22
-
-
84866491240
-
The neuron-astrocyte-microglia triad in normal brain aging and in a model of neuroinflammation in the rat hippocampus
-
Cerbai F., Lana D., Nosi D., Petkova-Kirova P., Zecchi S., Brothers H.M., Wenk G.L., Giovannini M.G. The neuron-astrocyte-microglia triad in normal brain aging and in a model of neuroinflammation in the rat hippocampus. PLoS One 2012, 7:e45250.
-
(2012)
PLoS One
, vol.7
, pp. e45250
-
-
Cerbai, F.1
Lana, D.2
Nosi, D.3
Petkova-Kirova, P.4
Zecchi, S.5
Brothers, H.M.6
Wenk, G.L.7
Giovannini, M.G.8
-
24
-
-
64449085359
-
A highly reproducible rotenone model of Parkinson's disease
-
Cannon J.R., Tapias V., Na H.M., Honick A.S., Drolet R.E., Greenamyre J.T. A highly reproducible rotenone model of Parkinson's disease. Neurobiol Dis 2009, 34:279-290.
-
(2009)
Neurobiol Dis
, vol.34
, pp. 279-290
-
-
Cannon, J.R.1
Tapias, V.2
Na, H.M.3
Honick, A.S.4
Drolet, R.E.5
Greenamyre, J.T.6
-
25
-
-
0036210298
-
Animal models of limbic epilepsies: what can they tell us?
-
Coulter D.A., McIntyre D.C., Loscher W. Animal models of limbic epilepsies: what can they tell us?. Brain Pathol 2002, 12:240-256.
-
(2002)
Brain Pathol
, vol.12
, pp. 240-256
-
-
Coulter, D.A.1
McIntyre, D.C.2
Loscher, W.3
-
26
-
-
44449147714
-
Up-regulation of insulin-like growth factor-II receptor in reactive astrocytes in the spinal cord of amyotrophic lateral sclerosis transgenic rats
-
Dagvajantsan B., Aoki M., Warita H., Suzuki N., Itoyama Y. Up-regulation of insulin-like growth factor-II receptor in reactive astrocytes in the spinal cord of amyotrophic lateral sclerosis transgenic rats. Tohoku J Exp Med 2008, 214:303-310.
-
(2008)
Tohoku J Exp Med
, vol.214
, pp. 303-310
-
-
Dagvajantsan, B.1
Aoki, M.2
Warita, H.3
Suzuki, N.4
Itoyama, Y.5
-
27
-
-
35148871293
-
2+ signals contribute to neuronal excitotoxicity after status epilepticus
-
2+ signals contribute to neuronal excitotoxicity after status epilepticus. J Neurosci 2007, 27:10674-10684.
-
(2007)
J Neurosci
, vol.27
, pp. 10674-10684
-
-
Ding, S.1
Fellin, T.2
Zhu, Y.3
Lee, S.Y.4
Auberson, Y.P.5
Meaney, D.F.6
Coulter, D.A.7
Carmignoto, G.8
Haydon, P.G.9
-
28
-
-
0035110055
-
Lysosomal membrane damage in soluble Aβ-mediated cell death in Alzheimer's disease
-
Ditaranto K., Tekirian T.L., Yang A.J. Lysosomal membrane damage in soluble Aβ-mediated cell death in Alzheimer's disease. Neurobiol Dis 2001, 8:19-31.
-
(2001)
Neurobiol Dis
, vol.8
, pp. 19-31
-
-
Ditaranto, K.1
Tekirian, T.L.2
Yang, A.J.3
-
29
-
-
38449093605
-
Glutamate and astrocytes - key players in human mesial temporal lobe epilepsy?
-
Eid T., Williamson A., Lee T.S.W., Petroff O.A., de Lanerolle N.C. Glutamate and astrocytes - key players in human mesial temporal lobe epilepsy?. Epilepsia 2008, 49(Suppl. 2):42-52.
-
(2008)
Epilepsia
, vol.49
, pp. 42-52
-
-
Eid, T.1
Williamson, A.2
Lee, T.S.W.3
Petroff, O.A.4
de Lanerolle, N.C.5
-
30
-
-
0037074932
-
Neurodegeneration in the Niemann Pick C mouse: glial involvement
-
German D.C., Liang C.L., Song T., Yazdani U., Xie C., Dietschy J.M. Neurodegeneration in the Niemann Pick C mouse: glial involvement. Neuroscience 2002, 109:437-450.
-
(2002)
Neuroscience
, vol.109
, pp. 437-450
-
-
German, D.C.1
Liang, C.L.2
Song, T.3
Yazdani, U.4
Xie, C.5
Dietschy, J.M.6
-
31
-
-
42549128696
-
A role for p53 in the regulation of lysosomal permeability by delta 9-tetrahydrocannabinol in rat cortical neurons: implications for neurodegeneration
-
Gowran A., Campbell V.A. A role for p53 in the regulation of lysosomal permeability by delta 9-tetrahydrocannabinol in rat cortical neurons: implications for neurodegeneration. J Neurochem 2008, 105:1513-1524.
-
(2008)
J Neurochem
, vol.105
, pp. 1513-1524
-
-
Gowran, A.1
Campbell, V.A.2
-
32
-
-
1442299204
-
The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system
-
Hawkes C., Kar S. The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system. Brain Res Rev 2004, 44:117-140.
-
(2004)
Brain Res Rev
, vol.44
, pp. 117-140
-
-
Hawkes, C.1
Kar, S.2
-
33
-
-
38149098258
-
Up-regulation of cation-independent mannose 6-phosphate receptor and endosomal-lysosomal markers in surviving neurons following 192 IgG-saporin administrations into the adult rat brain
-
Hawkes C., Kabogo D., Amritraj A., Kar S. Up-regulation of cation-independent mannose 6-phosphate receptor and endosomal-lysosomal markers in surviving neurons following 192 IgG-saporin administrations into the adult rat brain. Am J Pathol 2006, 169:1140-1154.
-
(2006)
Am J Pathol
, vol.169
, pp. 1140-1154
-
-
Hawkes, C.1
Kabogo, D.2
Amritraj, A.3
Kar, S.4
-
35
-
-
0028841090
-
Elevated cathepsin D expression in kainite-evoked rat brain neurodegeneration
-
Hetman M., Filipkowski R.K., Domagala W., Kaczmarek L. Elevated cathepsin D expression in kainite-evoked rat brain neurodegeneration. Exp Neurol 1995, 136:53-63.
-
(1995)
Exp Neurol
, vol.136
, pp. 53-63
-
-
Hetman, M.1
Filipkowski, R.K.2
Domagala, W.3
Kaczmarek, L.4
-
36
-
-
0034607595
-
Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain
-
Hopkins K.J., Wang G., Schmued L.C. Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain. Brain Res 2000, 864:69-80.
-
(2000)
Brain Res
, vol.864
, pp. 69-80
-
-
Hopkins, K.J.1
Wang, G.2
Schmued, L.C.3
-
37
-
-
0742289483
-
Lysosomes and mitochondria in the commitment to apoptosis: a potential role for cathepsin and AIF
-
Jaattela M., Cande C., Kroemer G. Lysosomes and mitochondria in the commitment to apoptosis: a potential role for cathepsin and AIF. Cell Death Differ 2004, 11:135-136.
-
(2004)
Cell Death Differ
, vol.11
, pp. 135-136
-
-
Jaattela, M.1
Cande, C.2
Kroemer, G.3
-
38
-
-
38449112392
-
Astrocytic function and its alteration in the epileptic brain
-
Jabs R., Seifert G., Steinhauser C. Astrocytic function and its alteration in the epileptic brain. Epilepsia 2008, 49(Suppl. 2):3-12.
-
(2008)
Epilepsia
, vol.49
, pp. 3-12
-
-
Jabs, R.1
Seifert, G.2
Steinhauser, C.3
-
39
-
-
33846287978
-
Cystatin B: mutation detection, alternative splicing and expression in progressive myoclonus epilepsy of Unverricht-Lundborg type (EPM1) patients
-
Joensuu T., Kuronen M., Alakurtti K., Tegelberg S., Hakala P., Aalto A., Huopaniemi L., Aula N., Michellucci R., Eriksson K., Lehesjoki A.E. Cystatin B: mutation detection, alternative splicing and expression in progressive myoclonus epilepsy of Unverricht-Lundborg type (EPM1) patients. Eur J Hum Genet 2007, 15:185-193.
-
(2007)
Eur J Hum Genet
, vol.15
, pp. 185-193
-
-
Joensuu, T.1
Kuronen, M.2
Alakurtti, K.3
Tegelberg, S.4
Hakala, P.5
Aalto, A.6
Huopaniemi, L.7
Aula, N.8
Michellucci, R.9
Eriksson, K.10
Lehesjoki, A.E.11
-
40
-
-
0242609099
-
Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine
-
Johansson A.C., Steen H., Ollinger K., Roberg K. Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine. Cell Death Differ 2003, 10:1253-1259.
-
(2003)
Cell Death Differ
, vol.10
, pp. 1253-1259
-
-
Johansson, A.C.1
Steen, H.2
Ollinger, K.3
Roberg, K.4
-
42
-
-
0033991670
-
Perforant path stimulation in rats produces seizures, loss of hippocampal neurons, and a deficit in spatial mapping which are reduced by prior MK-801
-
Kelsey J.E., Sanderson K.L., Frye C.A. Perforant path stimulation in rats produces seizures, loss of hippocampal neurons, and a deficit in spatial mapping which are reduced by prior MK-801. Behav Brain Res 2000, 107:59-69.
-
(2000)
Behav Brain Res
, vol.107
, pp. 59-69
-
-
Kelsey, J.E.1
Sanderson, K.L.2
Frye, C.A.3
-
43
-
-
40849098025
-
Cellular distribution of gamma-secretase subunit nicastrin in the developing and adult rat brains
-
Kodam A., Vetrivel K.S., Thinakaran G., Kar S. Cellular distribution of gamma-secretase subunit nicastrin in the developing and adult rat brains. Neurobiol Aging 2008, 29:724-738.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 724-738
-
-
Kodam, A.1
Vetrivel, K.S.2
Thinakaran, G.3
Kar, S.4
-
44
-
-
33847367323
-
Nonapoptotic functions of caspases: caspases as regulatory molecules for immunity and cell-fate determination
-
Kuranaga E., Miura M. Nonapoptotic functions of caspases: caspases as regulatory molecules for immunity and cell-fate determination. Trends Cell Biol 2007, 17:135-144.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 135-144
-
-
Kuranaga, E.1
Miura, M.2
-
45
-
-
0032848122
-
The up-regulation of endosomal-lysosomal components in amyloid beta-resistant cells
-
Li Y., Xu C., Schubert D. The up-regulation of endosomal-lysosomal components in amyloid beta-resistant cells. J Neurochem 1999, 73:1477-1482.
-
(1999)
J Neurochem
, vol.73
, pp. 1477-1482
-
-
Li, Y.1
Xu, C.2
Schubert, D.3
-
46
-
-
0019501929
-
Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates
-
Lothman E.W., Collins R.C. Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates. Brain Res 1981, 218:299-318.
-
(1981)
Brain Res
, vol.218
, pp. 299-318
-
-
Lothman, E.W.1
Collins, R.C.2
-
47
-
-
0043180531
-
Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders
-
Mattson M.P. Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders. Neuromol Med 2003, 3:65-94.
-
(2003)
Neuromol Med
, vol.3
, pp. 65-94
-
-
Mattson, M.P.1
-
48
-
-
0023544344
-
Age-related increase in a cathepsin D like protease that degrades brain microtubule-associated proteins
-
Matus A., Green G.D. Age-related increase in a cathepsin D like protease that degrades brain microtubule-associated proteins. Biochemistry 1987, 26:8083-8086.
-
(1987)
Biochemistry
, vol.26
, pp. 8083-8086
-
-
Matus, A.1
Green, G.D.2
-
49
-
-
84868234408
-
Mutant human APP exacerbates pathology in a mouse model of NPC and its reversal by a β-cyclodextrin
-
Maulik M., Ghoshal B., Kim J., Wang Y., Yang J., Westaway D., Kar S. Mutant human APP exacerbates pathology in a mouse model of NPC and its reversal by a β-cyclodextrin. Hum Mol Genet 2012, 21:4857-4875.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4857-4875
-
-
Maulik, M.1
Ghoshal, B.2
Kim, J.3
Wang, Y.4
Yang, J.5
Westaway, D.6
Kar, S.7
-
50
-
-
41649096358
-
Human cathepsin D
-
Minarowska A., Gacko M., Karwowska A., Minarowski L. Human cathepsin D. Folia Histochem Cytobiol 2008, 46:23-38.
-
(2008)
Folia Histochem Cytobiol
, vol.46
, pp. 23-38
-
-
Minarowska, A.1
Gacko, M.2
Karwowska, A.3
Minarowski, L.4
-
51
-
-
33644638355
-
Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain
-
Mouser P.E., Head E., Ha K.H., Rohn T.T. Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain. Am J Pathol 2006, 168:936-946.
-
(2006)
Am J Pathol
, vol.168
, pp. 936-946
-
-
Mouser, P.E.1
Head, E.2
Ha, K.H.3
Rohn, T.T.4
-
52
-
-
0035074341
-
The molecular machinery for lysosomes biogenesis
-
Mullins C., Bonifacino J.S. The molecular machinery for lysosomes biogenesis. Bioessays 2001, 23:333-343.
-
(2001)
Bioessays
, vol.23
, pp. 333-343
-
-
Mullins, C.1
Bonifacino, J.S.2
-
53
-
-
0017844923
-
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
-
Nadler J.V., Perry B.W., Cotman C.W. Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells. Nature 1978, 271:676-677.
-
(1978)
Nature
, vol.271
, pp. 676-677
-
-
Nadler, J.V.1
Perry, B.W.2
Cotman, C.W.3
-
54
-
-
0141539641
-
Neuronal and microglial cathepsins in aging and age-related diseases
-
Nakanishi H. Neuronal and microglial cathepsins in aging and age-related diseases. Aging Res Rev 2003, 2:367-381.
-
(2003)
Aging Res Rev
, vol.2
, pp. 367-381
-
-
Nakanishi, H.1
-
55
-
-
0141705329
-
Expression and activation of caspase 3 following status epilepticus in the rat
-
Narkilahti S., Pirttila T.J., Lukasiuk K., Tuunanen J., Pitkanen A. Expression and activation of caspase 3 following status epilepticus in the rat. Eur J Neurosci 2003, 18:1486-1496.
-
(2003)
Eur J Neurosci
, vol.18
, pp. 1486-1496
-
-
Narkilahti, S.1
Pirttila, T.J.2
Lukasiuk, K.3
Tuunanen, J.4
Pitkanen, A.5
-
56
-
-
84856251253
-
Long-term effects of recurrent neonatal seizures on neurobehavioral function and related gene expression and its intervention by inhibitor of cathepsin B
-
Ni H., Yan J., Zhang L., Feng X., Wu X. Long-term effects of recurrent neonatal seizures on neurobehavioral function and related gene expression and its intervention by inhibitor of cathepsin B. Neurochem Res 2012, 37:31-39.
-
(2012)
Neurochem Res
, vol.37
, pp. 31-39
-
-
Ni, H.1
Yan, J.2
Zhang, L.3
Feng, X.4
Wu, X.5
-
57
-
-
84858004619
-
Understanding the basic mechanisms underlying seizures in mesial temporal lobe epilepsy and possible therapeutic targets: a review
-
O'Dell C.M., Das A., Wallace G., Ray S.K., Banik N.L. Understanding the basic mechanisms underlying seizures in mesial temporal lobe epilepsy and possible therapeutic targets: a review. J Neurosci Res 2012, 90:913-924.
-
(2012)
J Neurosci Res
, vol.90
, pp. 913-924
-
-
O'Dell, C.M.1
Das, A.2
Wallace, G.3
Ray, S.K.4
Banik, N.L.5
-
58
-
-
0036827629
-
Insulin-like growth factor-II/mannose 6-phosphate receptor overexpression reduces growth of choriocarcinoma cells in vitro and in vivo
-
O'Gorman D.B., Weiss J., Hettiaratchi A., Firth S.M., Scott C.D. Insulin-like growth factor-II/mannose 6-phosphate receptor overexpression reduces growth of choriocarcinoma cells in vitro and in vivo. Endocrinology 2002, 143:4287-4294.
-
(2002)
Endocrinology
, vol.143
, pp. 4287-4294
-
-
O'Gorman, D.B.1
Weiss, J.2
Hettiaratchi, A.3
Firth, S.M.4
Scott, C.D.5
-
59
-
-
0022566936
-
Excitotoxic mechanism of epileptic brain damage
-
Raven Press, New York, A.V. Delgado-Escueta, A.A. Ward, D.M. Woodbury, R.J. Porter (Eds.)
-
Olney J.W., Collins R.C., Sloviter R.S. Excitotoxic mechanism of epileptic brain damage. Advances in neurology 1986, 857-877. Raven Press, New York. A.V. Delgado-Escueta, A.A. Ward, D.M. Woodbury, R.J. Porter (Eds.).
-
(1986)
Advances in neurology
, pp. 857-877
-
-
Olney, J.W.1
Collins, R.C.2
Sloviter, R.S.3
-
60
-
-
0031897739
-
Oxidative stress causes relocation of the lysosomal enzyme cathepsin D with ensuing apoptosis in neonatal rat cardiomyocytes
-
Roberg K., Ollinger K. Oxidative stress causes relocation of the lysosomal enzyme cathepsin D with ensuing apoptosis in neonatal rat cardiomyocytes. Am J Pathol 1998, 152:1151-1156.
-
(1998)
Am J Pathol
, vol.152
, pp. 1151-1156
-
-
Roberg, K.1
Ollinger, K.2
-
61
-
-
0001699915
-
Overview of the current animal models for human seizure and epileptic disorders
-
Sarkisian M.R. Overview of the current animal models for human seizure and epileptic disorders. Epilepsy Behav 2001, 2:201-216.
-
(2001)
Epilepsy Behav
, vol.2
, pp. 201-216
-
-
Sarkisian, M.R.1
-
62
-
-
0030901162
-
Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
-
Schmued L.C., Albertson C., Slikker W. Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res 1997, 751:37-46.
-
(1997)
Brain Res
, vol.751
, pp. 37-46
-
-
Schmued, L.C.1
Albertson, C.2
Slikker, W.3
-
63
-
-
0018862109
-
Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: a histological study
-
Schwob J.E., Fuller T., Price J.L., Olney J.W. Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: a histological study. Neurosceince 1980, 5:991-1014.
-
(1980)
Neurosceince
, vol.5
, pp. 991-1014
-
-
Schwob, J.E.1
Fuller, T.2
Price, J.L.3
Olney, J.W.4
-
64
-
-
0021045654
-
Kainic acid induced seizures: neurochemical and histopathological changes
-
Sperk G., Lassmann H., Baran H., Kish S.J., Seitelberger F., Hornykiewicz O. Kainic acid induced seizures: neurochemical and histopathological changes. Neuroscience 1983, 10:1301-1315.
-
(1983)
Neuroscience
, vol.10
, pp. 1301-1315
-
-
Sperk, G.1
Lassmann, H.2
Baran, H.3
Kish, S.J.4
Seitelberger, F.5
Hornykiewicz, O.6
-
65
-
-
78650545101
-
Hippocampal neurons exposed to the environmental contaminants methylmercury and polychlorinated biphenyls undergo cell death via parallel activation of calpains and lysosomal proteases
-
Tofighi R., Johansson C., Goldoni M., Ibrahim W.N., Gogvadze V., Mutti A., Ceccatelli S. Hippocampal neurons exposed to the environmental contaminants methylmercury and polychlorinated biphenyls undergo cell death via parallel activation of calpains and lysosomal proteases. Neurotox Res 2011, 19:183-194.
-
(2011)
Neurotox Res
, vol.19
, pp. 183-194
-
-
Tofighi, R.1
Johansson, C.2
Goldoni, M.3
Ibrahim, W.N.4
Gogvadze, V.5
Mutti, A.6
Ceccatelli, S.7
-
66
-
-
0031741571
-
Excitotoxin-induced neuronal death is associated with response of a unique intracellular aspartic proteinase, cathepsin E
-
Tominaga K., Nakanishi H., Yasuda Y., Yamamoto K. Excitotoxin-induced neuronal death is associated with response of a unique intracellular aspartic proteinase, cathepsin E. J Neurochem 1998, 71:2574-2584.
-
(1998)
J Neurochem
, vol.71
, pp. 2574-2584
-
-
Tominaga, K.1
Nakanishi, H.2
Yasuda, Y.3
Yamamoto, K.4
-
67
-
-
0036661021
-
Apoptotic pathways: involvement of lysosomal proteases
-
Turk B., Stoka V., Rozman-Pungercar J., Cirman T., Droga-Mazovec G., Oresic K., Turk V. Apoptotic pathways: involvement of lysosomal proteases. Biol Chem 2002, 383:1035-1044.
-
(2002)
Biol Chem
, vol.383
, pp. 1035-1044
-
-
Turk, B.1
Stoka, V.2
Rozman-Pungercar, J.3
Cirman, T.4
Droga-Mazovec, G.5
Oresic, K.6
Turk, V.7
-
68
-
-
0034615570
-
Lysosomal cysteine proteases: more than scavengers
-
Turk B., Turk D., Turk V. Lysosomal cysteine proteases: more than scavengers. Biochim Biophys Acta 2000, 1477:98-111.
-
(2000)
Biochim Biophys Acta
, vol.1477
, pp. 98-111
-
-
Turk, B.1
Turk, D.2
Turk, V.3
-
69
-
-
79955601720
-
Intraneuronal amyloid β oligomeric cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo
-
Umeda T., Tomiyama T., Sakama N., Tanaka S., Lambert M.P., Klein W.L., Mori H. Intraneuronal amyloid β oligomeric cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo. J Neurosci Res 2011, 89:1031-1042.
-
(2011)
J Neurosci Res
, vol.89
, pp. 1031-1042
-
-
Umeda, T.1
Tomiyama, T.2
Sakama, N.3
Tanaka, S.4
Lambert, M.P.5
Klein, W.L.6
Mori, H.7
-
70
-
-
33846805629
-
Novel cell death pathways induced by N-(4-hydroxyphenyl)retinamide: therapeutic implications
-
Vene R., Arena G., Poggi A., D'Arrigo C., Mormino M., Noonan D.M., Albini A., Tosetti F. Novel cell death pathways induced by N-(4-hydroxyphenyl)retinamide: therapeutic implications. Mol Cancer Ther 2007, 6:286-298.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 286-298
-
-
Vene, R.1
Arena, G.2
Poggi, A.3
D'Arrigo, C.4
Mormino, M.5
Noonan, D.M.6
Albini, A.7
Tosetti, F.8
-
71
-
-
58149474392
-
Kainate receptors in epilepsy and excitotoxicity
-
Vincent P., Mulle C. Kainate receptors in epilepsy and excitotoxicity. Neuroscience 2009, 158:309-323.
-
(2009)
Neuroscience
, vol.158
, pp. 309-323
-
-
Vincent, P.1
Mulle, C.2
-
72
-
-
77956131970
-
Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses
-
Vitner E.B., Dekel H., Zigdon H., Shachar T., Farfel-Becker T., Eilam R., Karlsson S., Futerman A.H. Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses. Hum Mol Genet 2010, 19:3583-3590.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3583-3590
-
-
Vitner, E.B.1
Dekel, H.2
Zigdon, H.3
Shachar, T.4
Farfel-Becker, T.5
Eilam, R.6
Karlsson, S.7
Futerman, A.H.8
-
73
-
-
79952281453
-
Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and its predominantly non-apoptotic
-
Wagner D.C., Riegelsberger U.M., Michalk S., Hartig W., Kranz A., Boltze J. Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and its predominantly non-apoptotic. Brain Res 2011, 1381:237-242.
-
(2011)
Brain Res
, vol.1381
, pp. 237-242
-
-
Wagner, D.C.1
Riegelsberger, U.M.2
Michalk, S.3
Hartig, W.4
Kranz, A.5
Boltze, J.6
-
74
-
-
32844464580
-
Lysosomal enzyme cathepsin B is involved in kainic acid-induced excitotoxicity in rat striatum
-
Wang Y., Gu Z., Cao Y., Liang Z., Han R., Bennett M.C., Qin Z. Lysosomal enzyme cathepsin B is involved in kainic acid-induced excitotoxicity in rat striatum. Brain Res 2006, 1071:245-249.
-
(2006)
Brain Res
, vol.1071
, pp. 245-249
-
-
Wang, Y.1
Gu, Z.2
Cao, Y.3
Liang, Z.4
Han, R.5
Bennett, M.C.6
Qin, Z.7
-
75
-
-
38949112123
-
An autophagic mechanism is involved in apoptotic death of art striatal neurons induced by the non-N-methyl-d-aspartate receptor agonist kainic acid
-
Wang Y., Han R., Liang Z.-Q., Wu J.-C., Zhang X.-D., Gu Z.-L., Qin Z.-H. An autophagic mechanism is involved in apoptotic death of art striatal neurons induced by the non-N-methyl-d-aspartate receptor agonist kainic acid. Autophagy 2008, 4:214-226.
-
(2008)
Autophagy
, vol.4
, pp. 214-226
-
-
Wang, Y.1
Han, R.2
Liang, Z.-Q.3
Wu, J.-C.4
Zhang, X.-D.5
Gu, Z.-L.6
Qin, Z.-H.7
-
76
-
-
20344388665
-
Kainic acid-mediated excitotoxicity as a model of neurodegeneration
-
Wang Q., Yu S., Simonyi A., Sun G.Y., Sun A.Y. Kainic acid-mediated excitotoxicity as a model of neurodegeneration. Mol Neurobiol 2005, 31:3-16.
-
(2005)
Mol Neurobiol
, vol.31
, pp. 3-16
-
-
Wang, Q.1
Yu, S.2
Simonyi, A.3
Sun, G.Y.4
Sun, A.Y.5
-
77
-
-
0031817004
-
Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA-074: a novel strategy for neuroprotection based on 'calpain-cathepsin hypothesis'
-
Yamashima T., Kohda Y., Tsuchiya K., Ueno T., Yamashita J., Yoshioka T., Kominami E. Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA-074: a novel strategy for neuroprotection based on 'calpain-cathepsin hypothesis'. Eur J Neurosci 1998, 10:1723-1733.
-
(1998)
Eur J Neurosci
, vol.10
, pp. 1723-1733
-
-
Yamashima, T.1
Kohda, Y.2
Tsuchiya, K.3
Ueno, T.4
Yamashita, J.5
Yoshioka, T.6
Kominami, E.7
-
78
-
-
0032526652
-
Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Aβ1-42 pathogenesis
-
Yang A.J., Chandswangbhuvana D., Margol L., Glabe C.G. Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Aβ1-42 pathogenesis. J Neurosci Res 1998, 52:691-698.
-
(1998)
J Neurosci Res
, vol.52
, pp. 691-698
-
-
Yang, A.J.1
Chandswangbhuvana, D.2
Margol, L.3
Glabe, C.G.4
-
79
-
-
52049098451
-
Cathepsin D: a cellular map
-
Zaidi N., Maurer A., Nieke S., Kalbacher H. Cathepsin D: a cellular map. Biochem Biophys Res Commun 2008, 376:5-9.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 5-9
-
-
Zaidi, N.1
Maurer, A.2
Nieke, S.3
Kalbacher, H.4
-
80
-
-
0036114279
-
Cation-independent mannose 6-phosphate receptor blocks apoptosis induced by Herpes simplex virus 1 mutants lacking glycoprotein D and is likely the target of antiapoptotic activity of the glycoprotein
-
Zhou G., Roizman B. Cation-independent mannose 6-phosphate receptor blocks apoptosis induced by Herpes simplex virus 1 mutants lacking glycoprotein D and is likely the target of antiapoptotic activity of the glycoprotein. J Virol 2002, 76:6197-6204.
-
(2002)
J Virol
, vol.76
, pp. 6197-6204
-
-
Zhou, G.1
Roizman, B.2
|