Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment

Analytical Chemistry

Volumn 86, Issue 21, 2014, Pages 10674-10683

  Debaene, François ^a,b   Bœuf, Amandine ^c   Wagner Rousset, Elsa ^c   Colas, Olivier ^c   Ayoub, Daniel ^c   Corvaïa, Nathalie ^c   Van Dorsselaer, Alain ^a,b   Beck, Alain ^c   Cianférani, Sarah ^a,b  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b CNRS   (France)

^c INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY-DRUG CONJUGATES; HIGH RESOLUTION;

CAC10-VCMMAE; IMMUNOCONJUGATES;

CHEMISTRY; CHROMATOGRAPHY, LIQUID; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MASS SPECTROMETRY; METHODS;

CHROMATOGRAPHY, LIQUID; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNOCONJUGATES; MASS SPECTROMETRY;

EID: 84908565774     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac502593n     Document Type: Article

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