Splenic TFH expansion participates in B-cell differentiation and antiplatelet-antibody production during immune thrombocytopenia

Blood

Volumn 124, Issue 18, 2014, Pages 2858-2866

  Audia, Sylvain ^a,b,c   Rossato, Marzia ^a   Santegoets, Kim ^a   Spijkers, Sanne ^a   Wichers, Catharina ^a   Bekker, Cornelis ^a   Bloem, Andries ^a   Boon, Louis ^d   Flinsenberg, Thijs ^a   Compeer, Ewoud ^a   Van Den Broek, Theo ^a   Facy, Olivier ^c   Ortega Deballon, Pablo ^c   Berthier, Sabine ^c   Leguy Seguin, Vanessa ^c   Martin, Laurent ^b,c   Ciudad, Marion ^b   Samson, Maxime ^b   Trad, Malika ^b   Lorcerie, Bernard ^c   Janikashvili, Nona ^b   Saas, Philippe ^b   Bonnotte, Bernard ^b,c   Radstake, Timothy R D J ^a   more..

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITÉ BOURGOGNE FRANCHE COMTÉ   (France)

^c DIJON UNIVERSITY HOSPITAL   (France)

^d BIOCEROS   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 LIGAND; CHEMOKINE RECEPTOR CXCR5; DAPSONE; IMMUNOGLOBULIN; INTERLEUKIN 21; STEROID; THROMBOCYTE ANTIBODY; IMMUNOGLOBULIN G; INTERLEUKIN DERIVATIVE; LEUKOCYTE ANTIGEN; MESSENGER RNA;

ADULT; AGED; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNE THROMBOCYTOPENIA; B LYMPHOCYTE DIFFERENTIATION; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL EXPANSION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LYMPHOID ORGAN; MALE; OVARY FOLLICLE CELL; PROTEIN EXPRESSION; SPLEEN; STEROID THERAPY; T FOLLICULAR HELPER CELL; T LYMPHOCYTE SUBPOPULATION; B LYMPHOCYTE; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; GENETICS; GERMINAL CENTER; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; MIDDLE AGED; PATHOLOGY; PHENOTYPE; PLASMA CELL; THROMBOCYTE;

ADULT; AGED; ANTIBODY FORMATION; ANTIGENS, CD; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; BLOOD PLATELETS; CD40 LIGAND; CELL DIFFERENTIATION; CELL PROLIFERATION; FEMALE; GERMINAL CENTER; HUMANS; IMMUNOGLOBULIN G; INTERLEUKINS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; PHENOTYPE; PLASMA CELLS; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; RNA, MESSENGER; SPLEEN; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84908563619     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-03-563445     Document Type: Article

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