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Volumn 103, Issue 4, 2004, Pages 1229-1236

Effect of a single injection of humanized anti-CD154 monoclonal antibody on the platelet-specific autoimmune response in patients with immune thrombocytopenic purpura

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD40 ANTIGEN; CD40 LIGAND; CD40 LIGAND MONOCLONAL ANTIBODY; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ANTIBODY; HUMANIZED CD40 LIGAND MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY IDEC 131; UNCLASSIFIED DRUG;

EID: 0842264044     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-06-2167     Document Type: Article
Times cited : (96)

References (44)
  • 1
    • 0037187949 scopus 로고    scopus 로고
    • Immune thrombocytopenic purpura
    • Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med. 2002;346:995-1008.
    • (2002) N Engl J Med , vol.346 , pp. 995-1008
    • Cines, D.B.1    Blanchette, V.S.2
  • 2
    • 0031011452 scopus 로고    scopus 로고
    • Autoimmune (idiopathic) thrombocytopenic purpura
    • Karpatkin S. Autoimmune (idiopathic) thrombocytopenic purpura. Lancet. 1997;349:1531-1536.
    • (1997) Lancet , vol.349 , pp. 1531-1536
    • Karpatkin, S.1
  • 3
    • 0036046036 scopus 로고    scopus 로고
    • Fifty years of idiopathic thrombocytopenic purpura (ITP): Management of refractory ITP in adults
    • Provan D, Newland A. Fifty years of idiopathic thrombocytopenic purpura (ITP): management of refractory ITP in adults. Br J Haematol. 2002;118:933-944.
    • (2002) Br J Haematol , vol.118 , pp. 933-944
    • Provan, D.1    Newland, A.2
  • 4
    • 0031042101 scopus 로고    scopus 로고
    • Therapy for adults with refractory chronic immune thrombocytopenic purpura
    • McMillan R. Therapy for adults with refractory chronic immune thrombocytopenic purpura. Ann Intern Med. 1997;126:307-314.
    • (1997) Ann Intern Med , vol.126 , pp. 307-314
    • McMillan, R.1
  • 5
    • 0028127939 scopus 로고
    • Spectrum of Ig classes, specificities, and titers of serum antiglycoproteins in chronic idiopathic thrombocytopenic purpura
    • He R, Reid DM, Jones CE, Shulman NR. Spectrum of Ig classes, specificities, and titers of serum antiglycoproteins in chronic idiopathic thrombocytopenic purpura. Blood. 1994;83:1024-1032.
    • (1994) Blood , vol.83 , pp. 1024-1032
    • He, R.1    Reid, D.M.2    Jones, C.E.3    Shulman, N.R.4
  • 6
    • 0030797843 scopus 로고    scopus 로고
    • Quantitation of platelet-specific autoantibodies in platelet eluates of ITP patients measured by a novel ELISA using purified glycoprotein complexes GPIIb/IIIa and GPlb/IX as antigens
    • Hürlmann-Forster M, Steiner B, von Felten A. Quantitation of platelet-specific autoantibodies in platelet eluates of ITP patients measured by a novel ELISA using purified glycoprotein complexes GPIIb/IIIa and GPlb/IX as antigens. Br J Haematol. 1997;98:328-335.
    • (1997) Br J Haematol , vol.98 , pp. 328-335
    • Hürlmann-Forster, M.1    Steiner, B.2    Von Felten, A.3
  • 7
    • 0032190549 scopus 로고    scopus 로고
    • Autoreactive T-cells to platelet GPIIb-IIIa in immune thrombocytopenic purpura: Role in production of anti-platelet autoantibody
    • Kuwana M, Kaburaki J, Ikeda Y. Autoreactive T-cells to platelet GPIIb-IIIa in immune thrombocytopenic purpura: role in production of anti-platelet autoantibody. J Clin Invest. 1998;102:1393-1402.
    • (1998) J Clin Invest , vol.102 , pp. 1393-1402
    • Kuwana, M.1    Kaburaki, J.2    Ikeda, Y.3
  • 8
    • 0035412364 scopus 로고    scopus 로고
    • Immunodominant epitopes on glycoprotein IIb-IIIa recognized by autoreactive T-cells in patients with immune thrombocytopenic purpura
    • Kuwana M, Kaburaki J, Kitasato H, et al. Immunodominant epitopes on glycoprotein IIb-IIIa recognized by autoreactive T-cells in patients with immune thrombocytopenic purpura. Blood. 2001;98:130-139.
    • (2001) Blood , vol.98 , pp. 130-139
    • Kuwana, M.1    Kaburaki, J.2    Kitasato, H.3
  • 11
    • 0030870889 scopus 로고    scopus 로고
    • CD40-CD40 ligand interaction in autoimmune disease
    • Datta SK, Kalled SL. CD40-CD40 ligand interaction in autoimmune disease. Arthritis Rheum. 1997;40:1735-1745.
    • (1997) Arthritis Rheum , vol.40 , pp. 1735-1745
    • Datta, S.K.1    Kalled, S.L.2
  • 12
    • 0027816953 scopus 로고
    • Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40
    • Durie FH, Fava RA, Foy TM, Aruffo A, Ledbetter JA, Noelle RJ. Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40. Science. 1993;261:1328-1330.
    • (1993) Science , vol.261 , pp. 1328-1330
    • Durie, F.H.1    Fava, R.A.2    Foy, T.M.3    Aruffo, A.4    Ledbetter, J.A.5    Noelle, R.J.6
  • 13
    • 0028852328 scopus 로고
    • Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
    • Mohan C, Shi Y, Laman JD, Datta SK. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J Immunol. 1995;154:1470-1480.
    • (1995) J Immunol , vol.154 , pp. 1470-1480
    • Mohan, C.1    Shi, Y.2    Laman, J.D.3    Datta, S.K.4
  • 14
    • 0032953939 scopus 로고    scopus 로고
    • Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis
    • Howard LM, Miga AJ, Vanderlugt CL, et al. Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. J Clin Invest. 1999;103:281-290.
    • (1999) J Clin Invest , vol.103 , pp. 281-290
    • Howard, L.M.1    Miga, A.J.2    Vanderlugt, C.L.3
  • 15
    • 0036344002 scopus 로고    scopus 로고
    • Transient anti-CD154-mediated immunotherapy of ongoing relapsing experimental autoimmune encephalomyelitis induces long-term inhibition of disease relapses
    • Howard LM, Dal Canto MC, Miller SD. Transient anti-CD154-mediated immunotherapy of ongoing relapsing experimental autoimmune encephalomyelitis induces long-term inhibition of disease relapses. J Neuroimmunol. 2002;129:58-65.
    • (2002) J Neuroimmunol , vol.129 , pp. 58-65
    • Howard, L.M.1    Dal Canto, M.C.2    Miller, S.D.3
  • 16
    • 0035338676 scopus 로고    scopus 로고
    • Blockade of CD40 ligand suppress chronic experimental myasthenia gravis by down-regulation of Th1 differentiation and up-regulation of CTLA-4
    • Im SH, Barchan D, Maiti PK, Fuchs S, Souroujon MC. Blockade of CD40 ligand suppress chronic experimental myasthenia gravis by down-regulation of Th1 differentiation and up-regulation of CTLA-4. J Immunol. 2001;166:6893-6898.
    • (2001) J Immunol , vol.166 , pp. 6893-6898
    • Im, S.H.1    Barchan, D.2    Maiti, P.K.3    Fuchs, S.4    Souroujon, M.C.5
  • 18
    • 0035119447 scopus 로고    scopus 로고
    • A humanized anti-human CD154 monoclonal antibody blocks CD154-CD40 mediated human B cell activation
    • Brams P, Black A, Padlan EA, et al. A humanized anti-human CD154 monoclonal antibody blocks CD154-CD40 mediated human B cell activation. Int Immunopharmacol. 2001;1:277-294.
    • (2001) Int Immunopharmacol , vol.1 , pp. 277-294
    • Brams, P.1    Black, A.2    Padlan, E.A.3
  • 19
    • 0035163042 scopus 로고    scopus 로고
    • Phase I clinical trial of a monoclonal antibody against CD40-ligand (IDEC-131) in patients with systemic lupus erythematosus
    • Davis JC Jr, Totoritis MC, Rosenberg J, Sklenar TA, Wofsy D. Phase I clinical trial of a monoclonal antibody against CD40-ligand (IDEC-131) in patients with systemic lupus erythematosus. J Rheumatol. 2001;28:95-101.
    • (2001) J Rheumatol , vol.28 , pp. 95-101
    • Davis Jr., J.C.1    Totoritis, M.C.2    Rosenberg, J.3    Sklenar, T.A.4    Wofsy, D.5
  • 20
    • 0036899589 scopus 로고    scopus 로고
    • Treatment of systemic lupus erythematosus by inhibition of T-cell costimulation with anti-CD154: A randomized, double-blind, placebo-controlled trial
    • Kalunian KC, Davis JC Jr, Merrill JT, Totoritis MC, Wofsy D. Treatment of systemic lupus erythematosus by inhibition of T-cell costimulation with anti-CD154: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2002;46:3251-3258.
    • (2002) Arthritis Rheum , vol.46 , pp. 3251-3258
    • Kalunian, K.C.1    Davis Jr., J.C.2    Merrill, J.T.3    Totoritis, M.C.4    Wofsy, D.5
  • 23
    • 0030919835 scopus 로고    scopus 로고
    • High-dose intravenous immune globulin and the response to splenectomy in patients with idiopathic thrombocytopenic purpura
    • Law C, Marcaccio M, Tam P, Heddle N, Kelton JG. High-dose intravenous immune globulin and the response to splenectomy in patients with idiopathic thrombocytopenic purpura. N Engl J Med. 1997;336:1494-1498.
    • (1997) N Engl J Med , vol.336 , pp. 1494-1498
    • Law, C.1    Marcaccio, M.2    Tam, P.3    Heddle, N.4    Kelton, J.G.5
  • 24
    • 0036533583 scopus 로고    scopus 로고
    • Spleen is a primary site for activation of platelet-reactive T and B cells in patients with immune thrombocytopenic purpura
    • Kuwana M, Okazaki Y, Kaburaki J, Kawakami Y, Ikeda Y. Spleen is a primary site for activation of platelet-reactive T and B cells in patients with immune thrombocytopenic purpura. J Immunol. 2002;168:3875-3682.
    • (2002) J Immunol , vol.168 , pp. 3875-3682
    • Kuwana, M.1    Okazaki, Y.2    Kaburaki, J.3    Kawakami, Y.4    Ikeda, Y.5
  • 25
    • 0037355330 scopus 로고    scopus 로고
    • Detection of circulating B cells secreting platelet-specific autoantibody is useful in the diagnosis of autoimmune thrombocytopenia
    • Kuwana M, Okazaki Y, Kaburaki J, Ikeda Y. Detection of circulating B cells secreting platelet-specific autoantibody is useful in the diagnosis of autoimmune thrombocytopenia. Am J Med. 2003;114:322-325.
    • (2003) Am J Med , vol.114 , pp. 322-325
    • Kuwana, M.1    Okazaki, Y.2    Kaburaki, J.3    Ikeda, Y.4
  • 26
    • 0037438507 scopus 로고    scopus 로고
    • Suppression of autoreactive T-cell response to glycoprotein IIb/IIIa by blockade of CD40/CD154 interaction: Implications for treatment of immune thrombocytopenic purpura
    • Kuwana M, Kawakami Y, Ikeda Y. Suppression of autoreactive T-cell response to glycoprotein IIb/IIIa by blockade of CD40/CD154 interaction: implications for treatment of immune thrombocytopenic purpura. Blood. 2003;101:621-623.
    • (2003) Blood , vol.101 , pp. 621-623
    • Kuwana, M.1    Kawakami, Y.2    Ikeda, Y.3
  • 27
    • 0029057102 scopus 로고
    • Human antibody response in human peripheral blood leukocyte/severe combined immunodeficient chimeric model is dependent on B and T-cell costimulation via CD40/CD40 ligand
    • Chen FA, Williams SS, Fanslow WC, Bankert RB. Human antibody response in human peripheral blood leukocyte/severe combined immunodeficient chimeric model is dependent on B and T-cell costimulation via CD40/CD40 ligand. J Immunol. 1995;155:2833-2840.
    • (1995) J Immunol , vol.155 , pp. 2833-2840
    • Chen, F.A.1    Williams, S.S.2    Fanslow, W.C.3    Bankert, R.B.4
  • 28
    • 0036272915 scopus 로고    scopus 로고
    • The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus
    • Huang W, Sinha J, Newman J, et al. The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus. Arthritis Rheum. 2002;46:1554-1562.
    • (2002) Arthritis Rheum , vol.46 , pp. 1554-1562
    • Huang, W.1    Sinha, J.2    Newman, J.3
  • 29
    • 0037333857 scopus 로고    scopus 로고
    • A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis
    • Boumpas DT, Furie R, Manzi S, et al. A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis. Arthritis Rheum. 2003;48:719-727.
    • (2003) Arthritis Rheum , vol.48 , pp. 719-727
    • Boumpas, D.T.1    Furie, R.2    Manzi, S.3
  • 30
    • 0037082457 scopus 로고    scopus 로고
    • Long-term salvage therapy with cyclosporin A in refractory idiopathic thrombocytopenic purpura
    • Emilia G, Morselli M, Luppi M, et al. Long-term salvage therapy with cyclosporin A in refractory idiopathic thrombocytopenic purpura. Blood. 2002;99:1482-1485.
    • (2002) Blood , vol.99 , pp. 1482-1485
    • Emilia, G.1    Morselli, M.2    Luppi, M.3
  • 31
    • 0034786378 scopus 로고    scopus 로고
    • The effect of treatment with Campath-1H in patients with autoimmune cytopenias
    • Willis F, Marsh JC, Bevan DH, et al. The effect of treatment with Campath-1H in patients with autoimmune cytopenias. Br J Haematol. 2001;114:891-898.
    • (2001) Br J Haematol , vol.114 , pp. 891-898
    • Willis, F.1    Marsh, J.C.2    Bevan, D.H.3
  • 32
    • 0035883071 scopus 로고    scopus 로고
    • Rituximab chimeric anti-CD20 monoclonal antibody treatment for adults with chronic idiopathic thrombocytopenic purpura
    • Stasi R, Pagano A, Stipa E, Amadori S. Rituximab chimeric anti-CD20 monoclonal antibody treatment for adults with chronic idiopathic thrombocytopenic purpura. Blood. 2001;98:952-957.
    • (2001) Blood , vol.98 , pp. 952-957
    • Stasi, R.1    Pagano, A.2    Stipa, E.3    Amadori, S.4
  • 34
    • 0036201121 scopus 로고    scopus 로고
    • CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/ DC regulatory cells
    • Homann D, Jahreis A, Wilfe T, et al. CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells. Immunity. 2002;16:403-415.
    • (2002) Immunity , vol.16 , pp. 403-415
    • Homann, D.1    Jahreis, A.2    Wilfe, T.3
  • 35
    • 12244279684 scopus 로고    scopus 로고
    • Safety and effect on platelet count of single-dose monoclonal antibody to CD40 ligand (ANTOVA) in patients with chronic ITP
    • George J, Raskob G, Lichtin A, et al. Safety and effect on platelet count of single-dose monoclonal antibody to CD40 ligand (ANTOVA) in patients with chronic ITP [abstract]. Blood. 1998;92:707a.
    • (1998) Blood , vol.92
    • George, J.1    Raskob, G.2    Lichtin, A.3
  • 36
    • 0003275567 scopus 로고    scopus 로고
    • Humanized monoclonal anti-CD40 ligand antibody (hu5c8) rescue therapy of 15 adults with severe chronic refractory ITP
    • Bussel J, Wissert M, Oates B, et al. Humanized monoclonal anti-CD40 ligand antibody (hu5c8) rescue therapy of 15 adults with severe chronic refractory ITP [abstract]. Blood. 1999;94:646a.
    • (1999) Blood , vol.94
    • Bussel, J.1    Wissert, M.2    Oates, B.3
  • 37
    • 0003356988 scopus 로고    scopus 로고
    • Safety and effect on platelet count of repeated doses of monoclonal antibody to CD40 ligand in patients with chronic ITP
    • George J, Raskob G, Bussel J, et al. Safety and effect on platelet count of repeated doses of monoclonal antibody to CD40 ligand in patients with chronic ITP [abstract]. Blood. 1999;94:19a.
    • (1999) Blood , vol.94
    • George, J.1    Raskob, G.2    Bussel, J.3
  • 39
    • 0033965079 scopus 로고    scopus 로고
    • Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand
    • Kawai T, Andrews D, Colvin RB, Sachs DH, Cosimi AB. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand [letter]. Nat Med. 2000;6:114.
    • (2000) Nat Med , vol.6 , pp. 114
    • Kawai, T.1    Andrews, D.2    Colvin, R.B.3    Sachs, D.H.4    Cosimi, A.B.5
  • 40
    • 0032484987 scopus 로고    scopus 로고
    • CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
    • Henn V, Slupsky JR, Grafe M, et al. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature. 1998;39:591-594.
    • (1998) Nature , vol.39 , pp. 591-594
    • Henn, V.1    Slupsky, J.R.2    Grafe, M.3
  • 41
    • 0035883087 scopus 로고    scopus 로고
    • The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40
    • Henn V, Steinbach S, Büchner K, Presek P, Kroczek RA. The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. Blood. 2001;98:1047-1054.
    • (2001) Blood , vol.98 , pp. 1047-1054
    • Henn, V.1    Steinbach, S.2    Büchner, K.3    Presek, P.4    Kroczek, R.A.5
  • 44
    • 0037105322 scopus 로고    scopus 로고
    • Variation in the ordered structure of complexes between CD154 and anti-CD154 monoclonal antibodies
    • Ferrant JL, Wilson CA, Benjamin CD. Variation in the ordered structure of complexes between CD154 and anti-CD154 monoclonal antibodies. Mol Immunol. 2002;39:77-84.
    • (2002) Mol Immunol , vol.39 , pp. 77-84
    • Ferrant, J.L.1    Wilson, C.A.2    Benjamin, C.D.3


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