-
1
-
-
84890961378
-
New therapies for diabetic kidney disease
-
Himmelfarb J, Tuttle KR. New therapies for diabetic kidney disease. New Engl J Med 2013; 369: 2549-2550
-
(2013)
New Engl J Med
, vol.369
, pp. 2549-2550
-
-
Himmelfarb, J.1
Tuttle, K.R.2
-
2
-
-
84880313916
-
Evolving importance of kidney disease: From subspecialty to global health burden
-
Eckardt KU, Coresh J, Devuyst O, et al. Evolving importance of kidney disease: from subspecialty to global health burden. Lancet 2013; 382: 158-169
-
(2013)
Lancet
, vol.382
, pp. 158-169
-
-
Eckardt, K.U.1
Coresh, J.2
Devuyst, O.3
-
3
-
-
12344250764
-
Chronic kidney disease: The global challenge
-
Meguid El Nahas A, Bello AK. Chronic kidney disease: the global challenge. Lancet 2005; 365: 331-340
-
(2005)
Lancet
, vol.365
, pp. 331-340
-
-
Meguid El Nahas, A.1
Bello, A.K.2
-
4
-
-
84873025518
-
Podocyte biology and pathogenesis of kidney disease
-
Reiser J, Sever S. Podocyte biology and pathogenesis of kidney disease. Ann Rev Med 2013; 64: 357-366
-
(2013)
Ann Rev Med
, vol.64
, pp. 357-366
-
-
Reiser, J.1
Sever, S.2
-
5
-
-
0023859136
-
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
-
Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332: 411-415
-
(1988)
Nature
, vol.332
, pp. 411-415
-
-
Yanagisawa, M.1
Kurihara, H.2
Kimura, S.3
-
6
-
-
48849094089
-
Endothelin: 20 years from discovery to therapy
-
Barton M, Yanagisawa M. Endothelin: 20 years from discovery to therapy. Can J Physiol Pharmacol 2008; 86: 485-498
-
(2008)
Can J Physiol Pharmacol
, vol.86
, pp. 485-498
-
-
Barton, M.1
Yanagisawa, M.2
-
7
-
-
78751672175
-
Regulation of blood pressure and salt homeostasis by endothelin
-
Kohan DE, Rossi NF, Inscho EW, et al. Regulation of blood pressure and salt homeostasis by endothelin. Physiol Rev 2011; 91: 1-77
-
(2011)
Physiol Rev
, vol.91
, pp. 1-77
-
-
Kohan, D.E.1
Rossi, N.F.2
Inscho, E.W.3
-
8
-
-
84880402164
-
Myocardial, smooth muscle, nephron and collecting duct gene targeting reveals the organ sites of endothelin A receptor antagonist fluid retention
-
Stuart D, Chapman M, Rees S, et al. Myocardial, smooth muscle, nephron and collecting duct gene targeting reveals the organ sites of endothelin A receptor antagonist fluid retention. J Pharmacol Exp Ther 2013; 346: 182-189
-
(2013)
J Pharmacol Exp Ther
, vol.346
, pp. 182-189
-
-
Stuart, D.1
Chapman, M.2
Rees, S.3
-
9
-
-
84870329393
-
Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion
-
Stuart D, Rees S, Woodward SK, et al. Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion. BMC Nephrol 2012; 13: 166
-
(2012)
BMC Nephrol
, vol.13
, pp. 166
-
-
Stuart, D.1
Rees, S.2
Woodward, S.K.3
-
10
-
-
33750301234
-
Endothelin role in kidney acidification
-
Wesson DE. Endothelin role in kidney acidification. Semin Nephrol 2006; 26: 393-398
-
(2006)
Semin Nephrol
, vol.26
, pp. 393-398
-
-
Wesson, D.E.1
-
11
-
-
50249165289
-
Reversal of proteinuric renal disease and the emerging role of endothelin
-
Barton M. Reversal of proteinuric renal disease and the emerging role of endothelin. Nat Clin Pract Nephrol 2008; 4: 490-501
-
(2008)
Nat Clin Pract Nephrol
, vol.4
, pp. 490-501
-
-
Barton, M.1
-
13
-
-
79959526176
-
Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease
-
Saleh MA, Pollock JS, Pollock DM. Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease. J Pharmacol Exp Ther 2011; 338: 263-270
-
(2011)
J Pharmacol Exp Ther
, vol.338
, pp. 263-270
-
-
Saleh, M.A.1
Pollock, J.S.2
Pollock, D.M.3
-
14
-
-
84859842709
-
ENOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype
-
Li F, Hagaman JR, Kim HS, et al. eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype. J Am Soc Nephrol 2012; 23: 652-660
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 652-660
-
-
Li, F.1
Hagaman, J.R.2
Kim, H.S.3
-
15
-
-
0025079136
-
Endothelin stimulates angiotensin i to angiotensin II conversion in cultured pulmonary artery endothelial cells
-
Kawaguchi H, Sawa H, Yasuda H. Endothelin stimulates angiotensin I to angiotensin II conversion in cultured pulmonary artery endothelial cells. J Mol Cell Cardiol 1990; 22: 839-842
-
(1990)
J Mol Cell Cardiol
, vol.22
, pp. 839-842
-
-
Kawaguchi, H.1
Sawa, H.2
Yasuda, H.3
-
16
-
-
0031590298
-
Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: Role of ETA receptors for endothelin regulation
-
Barton M, Shaw S, dUscio LV, et al. Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA receptors for endothelin regulation. Biochem Biophys Res Commun 1997; 238: 861-865
-
(1997)
Biochem Biophys Res Commun
, vol.238
, pp. 861-865
-
-
Barton, M.1
Shaw, S.2
Duscio, L.V.3
-
17
-
-
84885320788
-
Progressive endothelin-1 gene activation initiates chronic/end-stage renal disease following experimental ischemic/reperfusion injury
-
Zager RA, Johnson AC, Andress D, et al. Progressive endothelin-1 gene activation initiates chronic/end-stage renal disease following experimental ischemic/reperfusion injury. Kidney Int 2013; 84: 703-712
-
(2013)
Kidney Int
, vol.84
, pp. 703-712
-
-
Zager, R.A.1
Johnson, A.C.2
Andress, D.3
-
19
-
-
33646134236
-
Mechanisms of disease: Focal segmental glomerulosclerosis
-
Meyrier A. Mechanisms of disease: focal segmental glomerulosclerosis. Nat Clin Prac Nephrol 2005; 1: 44-54
-
(2005)
Nat Clin Prac Nephrol
, vol.1
, pp. 44-54
-
-
Meyrier, A.1
-
21
-
-
9644282849
-
Role of podocytes for reversal of glomerulosclerosis and proteinuria in the aging kidney after endothelin inhibition
-
Ortmann J, Amann K, Brandes RP, et al. Role of podocytes for reversal of glomerulosclerosis and proteinuria in the aging kidney after endothelin inhibition. Hypertension 2004; 44: 974-981
-
(2004)
Hypertension
, vol.44
, pp. 974-981
-
-
Ortmann, J.1
Amann, K.2
Brandes, R.P.3
-
22
-
-
34447109827
-
Shigatoxin-induced endothelin-1 expression in cultured podocytes autocrinally mediates actin remodeling
-
Morigi M, Buelli S, Zanchi C, et al. Shigatoxin-induced endothelin-1 expression in cultured podocytes autocrinally mediates actin remodeling. Am J Pathol 2006; 169: 1965-1975
-
(2006)
Am J Pathol
, vol.169
, pp. 1965-1975
-
-
Morigi, M.1
Buelli, S.2
Zanchi, C.3
-
23
-
-
20944437139
-
In response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: Implication for permselective dysfunction of chronic nephropathies
-
Morigi M, Buelli S, Angioletti S, et al. In response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: implication for permselective dysfunction of chronic nephropathies. Am J Pathol 2005; 166: 1309-1320
-
(2005)
Am J Pathol
, vol.166
, pp. 1309-1320
-
-
Morigi, M.1
Buelli, S.2
Angioletti, S.3
-
24
-
-
78149277201
-
Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat
-
Saleh MA, Boesen EI, Pollock JS, et al. Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat. Hypertension 2010; 56: 942-949
-
(2010)
Hypertension
, vol.56
, pp. 942-949
-
-
Saleh, M.A.1
Boesen, E.I.2
Pollock, J.S.3
-
25
-
-
1842411863
-
Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension
-
Hocher B, Thone-Reineke C, Rohmeiss P, et al. Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension. J Clin Invest 1997; 99: 1380-1389
-
(1997)
J Clin Invest
, vol.99
, pp. 1380-1389
-
-
Hocher, B.1
Thone-Reineke, C.2
Rohmeiss, P.3
-
26
-
-
0027203495
-
A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression
-
Benigni A, Zoja C, Corna D, et al. A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression. Kidney Int 1993; 44: 440-444
-
(1993)
Kidney Int
, vol.44
, pp. 440-444
-
-
Benigni, A.1
Zoja, C.2
Corna, D.3
-
27
-
-
84878913517
-
Endothelin, kidney disease, and hypertension
-
Speed JS, Pollock DM. Endothelin, kidney disease, and hypertension. Hypertension 2013; 61: 1142-1145
-
(2013)
Hypertension
, vol.61
, pp. 1142-1145
-
-
Speed, J.S.1
Pollock, D.M.2
-
28
-
-
0025369479
-
Enhanced secretion of endothelin-1 by elevated glucose levels from cultured bovine aortic endothelial cells
-
Yamauchi T, Ohnaka K, Takayanagi R, et al. Enhanced secretion of endothelin-1 by elevated glucose levels from cultured bovine aortic endothelial cells. FEBS Lett 1990; 267: 16-18
-
(1990)
FEBS Lett
, vol.267
, pp. 16-18
-
-
Yamauchi, T.1
Ohnaka, K.2
Takayanagi, R.3
-
29
-
-
0029088469
-
High glucose alters actin assembly in glomerular mesangial and epithelial cells
-
Zhou X, Hurst RD, Templeton D, et al. High glucose alters actin assembly in glomerular mesangial and epithelial cells. Lab Invest 1995; 73: 372-383
-
(1995)
Lab Invest
, vol.73
, pp. 372-383
-
-
Zhou, X.1
Hurst, R.D.2
Templeton, D.3
-
30
-
-
45149133361
-
Preeclamptic sera induce nephrin shedding from podocytes through endothelin-1 release by endothelial glomerular cells
-
Collino F, Bussolati B, Gerbaudo E, et al. Preeclamptic sera induce nephrin shedding from podocytes through endothelin-1 release by endothelial glomerular cells. Am J Physiol Renal Physiol 2008; 294: F1185-F1194
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, pp. F1185-F1194
-
-
Collino, F.1
Bussolati, B.2
Gerbaudo, E.3
-
31
-
-
0031891447
-
Unselective inhibition of endothelin receptors reduces renal dysfunction in experimental diabetes
-
Benigni A, Colosio V, Brena C, et al. Unselective inhibition of endothelin receptors reduces renal dysfunction in experimental diabetes. Diabetes 1998; 47: 450-456
-
(1998)
Diabetes
, vol.47
, pp. 450-456
-
-
Benigni, A.1
Colosio, V.2
Brena, C.3
-
32
-
-
33845979878
-
Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism
-
Sasser JM, Sullivan JC, Hobbs JL, et al. Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism. J Am Soc Nephrol 2007; 18: 143-154
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 143-154
-
-
Sasser, J.M.1
Sullivan, J.C.2
Hobbs, J.L.3
-
33
-
-
70350704811
-
Unlike each drug alone, Lisinopril if combined with avosentan promotes regression of renal lesions in experimental diabetes
-
Gagliardini E, Corna D, Zoja C, et al. Unlike each drug alone, Lisinopril if combined with avosentan promotes regression of renal lesions in experimental diabetes. Am J Physiol Renal Physiol 2009; 297: F1448-F1456
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F1448-F1456
-
-
Gagliardini, E.1
Corna, D.2
Zoja, C.3
-
34
-
-
0141590203
-
Renal damage in the SHR/N-cp type 2 diabetes model: Comparison of an angiotensin-converting enzyme inhibitor and endothelin receptor blocker
-
Gross ML, Ritz E, Schoof A, et al. Renal damage in the SHR/N-cp type 2 diabetes model: comparison of an angiotensin-converting enzyme inhibitor and endothelin receptor blocker. Lab Invest 2003; 83: 1267-1277
-
(2003)
Lab Invest
, vol.83
, pp. 1267-1277
-
-
Gross, M.L.1
Ritz, E.2
Schoof, A.3
-
35
-
-
78049283275
-
Therapeutic potential of endothelin receptor antagonists for chronic proteinuric renal disease in humans
-
Barton M. Therapeutic potential of endothelin receptor antagonists for chronic proteinuric renal disease in humans. Biochim Biophys Acta 2010; 1802: 1203-1213
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 1203-1213
-
-
Barton, M.1
-
36
-
-
84891705751
-
Addition of eta receptor blockade increases renoprotection provided by renin-Angiotensin system blockade in 5/6 nephrectomized ren-2 transgenic rats
-
in press
-
Certikova Chabova V, Vernerova Z, Kujal P, et al. Addition of ETA receptor blockade increases renoprotection provided by renin-Angiotensin system blockade in 5/6 nephrectomized Ren-2 transgenic rats. Life Sci 2014; (in press
-
(2014)
Life Sci
-
-
Certikova Chabova, V.1
Vernerova, Z.2
Kujal, P.3
-
37
-
-
0035090401
-
Regression of renal vascular fibrosis by endothelin receptor antagonism
-
Boffa JJ, Tharaux PL, Dussaule JC, et al. Regression of renal vascular fibrosis by endothelin receptor antagonism. Hypertension 2001; 37: 490-496
-
(2001)
Hypertension
, vol.37
, pp. 490-496
-
-
Boffa, J.J.1
Tharaux, P.L.2
Dussaule, J.C.3
-
38
-
-
33645281135
-
Reversal of renal lesions following interruption of nitric oxide synthesis inhibition in transgenic mice
-
Placier S, Boffa JJ, Dussaule JC, et al. Reversal of renal lesions following interruption of nitric oxide synthesis inhibition in transgenic mice. Nephrol Dial Transplant 2006; 21: 881-888
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 881-888
-
-
Placier, S.1
Boffa, J.J.2
Dussaule, J.C.3
-
39
-
-
33750238503
-
Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension
-
Opocensky M, Kramer HJ, Backer A, et al. Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension. Hypertension 2006; 48: 965-971
-
(2006)
Hypertension
, vol.48
, pp. 965-971
-
-
Opocensky, M.1
Kramer, H.J.2
Backer, A.3
-
40
-
-
43849113758
-
Late-onset endothelin receptor blockade in hypertensive heterozygous REN-2 transgenic rats
-
Vernerova Z, Kramer HJ, Backer A, et al. Late-onset endothelin receptor blockade in hypertensive heterozygous REN-2 transgenic rats. Vascul Pharmacol 2008; 48: 165-173
-
(2008)
Vascul Pharmacol
, vol.48
, pp. 165-173
-
-
Vernerova, Z.1
Kramer, H.J.2
Backer, A.3
-
41
-
-
0031606120
-
Endothelin-A receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats
-
Kasaab S, Miller MT, Novak J, et al. Endothelin-A receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats. Hypertension 1998; 31: 397-402
-
(1998)
Hypertension
, vol.31
, pp. 397-402
-
-
Kasaab, S.1
Miller, M.T.2
Novak, J.3
-
42
-
-
16744362572
-
Dysfunctional renal nitric oxide synthase as a determinant of salt-sensitive hypertension: Mechanisms of renal artery endothelial dysfunction and role of endothelin for vascular hypertrophy and glomerulosclerosis
-
Barton M, Vos I, Shaw S, et al. Dysfunctional renal nitric oxide synthase as a determinant of salt-sensitive hypertension: mechanisms of renal artery endothelial dysfunction and role of endothelin for vascular hypertrophy and glomerulosclerosis. J Am Soc Nephrol 2000; 11: 835-845
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 835-845
-
-
Barton, M.1
Vos, I.2
Shaw, S.3
-
43
-
-
84897954458
-
Disparate effects of single endothelin-A and-B receptor blocker therapy on the progression of renal injury in advanced renovascular disease
-
Chade AR, Stewart NJ, Peavy PR. Disparate effects of single endothelin-A and-B receptor blocker therapy on the progression of renal injury in advanced renovascular disease. Kidney Int 2014; 85: 833-844
-
(2014)
Kidney Int
, vol.85
, pp. 833-844
-
-
Chade, A.R.1
Stewart, N.J.2
Peavy, P.R.3
-
44
-
-
79960095341
-
Endothelin-A receptor blockade slows the progression of renal injury in experimental renovascular disease
-
Kelsen S, Hall JE, Chade AR. Endothelin-A receptor blockade slows the progression of renal injury in experimental renovascular disease. Am J Physiol Renal Physiol 2011; 301: F218-F225
-
(2011)
Am J Physiol Renal Physiol
, vol.301
, pp. F218-F225
-
-
Kelsen, S.1
Hall, J.E.2
Chade, A.R.3
-
45
-
-
84926111700
-
Endothelin and podocyte injury in chronic kidney disease
-
Fligny C, Barton M, Tharaux PL. Endothelin and podocyte injury in chronic kidney disease. Contrib Nephrol 2011; 172: 120-138
-
(2011)
Contrib Nephrol
, vol.172
, pp. 120-138
-
-
Fligny, C.1
Barton, M.2
Tharaux, P.L.3
-
46
-
-
0031058834
-
Age-related glomerulosclerosis and interstitial fibrosis in Milan normotensive rats: A podocyte disease
-
Floege J, Hackmann B, Kliem V, et al. Age-related glomerulosclerosis and interstitial fibrosis in Milan normotensive rats: a podocyte disease. Kidney Int 1997; 51: 230-243
-
(1997)
Kidney Int
, vol.51
, pp. 230-243
-
-
Floege, J.1
Hackmann, B.2
Kliem, V.3
-
47
-
-
80052333245
-
Activation of RhoA in podocytes induces focal segmental glomerulosclerosis
-
Zhu L, Jiang R, Aoudjit L, et al. Activation of RhoA in podocytes induces focal segmental glomerulosclerosis. J Am Soc Nephrol 2011; 22: 1621-1630
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1621-1630
-
-
Zhu, L.1
Jiang, R.2
Aoudjit, L.3
-
48
-
-
77951169411
-
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
-
Hartleben B, Godel M, Meyer-Schwesinger C, et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest 2010; 120: 1084-1096
-
(2010)
J Clin Invest
, vol.120
, pp. 1084-1096
-
-
Hartleben, B.1
Godel, M.2
Meyer-Schwesinger, C.3
-
49
-
-
11144247272
-
Anatomically distinct activation of endothelin-3 and the L-Arginine/nitric oxide pathway in the kidney with advanced aging
-
Lattmann T, Shaw S, Munter K, et al. Anatomically distinct activation of endothelin-3 and the L-Arginine/nitric oxide pathway in the kidney with advanced aging. Biochem Biophys Res Commun 2005; 327: 234-241
-
(2005)
Biochem Biophys Res Commun
, vol.327
, pp. 234-241
-
-
Lattmann, T.1
Shaw, S.2
Munter, K.3
-
50
-
-
0032523239
-
Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control
-
Di Cunto F, Topley G, Calautti E, et al. Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control. Science 1998; 280: 1069-1072
-
(1998)
Science
, vol.280
, pp. 1069-1072
-
-
Di Cunto, F.1
Topley, G.2
Calautti, E.3
-
51
-
-
0032875388
-
The lack of a functional p21(WAF1/CIP1) gene ameliorates progression to chronic renal failure
-
Megyesi J, Price PM, Tamayo E, et al. The lack of a functional p21(WAF1/CIP1) gene ameliorates progression to chronic renal failure. Proc Natl Acad Sci USA 1999; 96: 10830-10835
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10830-10835
-
-
Megyesi, J.1
Price, P.M.2
Tamayo, E.3
-
52
-
-
0027401818
-
Influence of cardiovascular damage and residual renal function on plasma endothelin in chronic renal failure
-
Mallamaci F, Parlongo S, Zoccali C. Influence of cardiovascular damage and residual renal function on plasma endothelin in chronic renal failure. Nephron 1993; 63: 291-295
-
(1993)
Nephron
, vol.63
, pp. 291-295
-
-
Mallamaci, F.1
Parlongo, S.2
Zoccali, C.3
-
53
-
-
41749086422
-
Endothelin-1 levels and albuminuria in patients with type 2 diabetes mellitus
-
Zanatta CM, Gerchman F, Burttet L, et al. Endothelin-1 levels and albuminuria in patients with type 2 diabetes mellitus. Diabetes Res Clin Pract 2008; 80: 299-304
-
(2008)
Diabetes Res Clin Pract
, vol.80
, pp. 299-304
-
-
Zanatta, C.M.1
Gerchman, F.2
Burttet, L.3
-
54
-
-
79955539810
-
Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co-morbidity
-
Lilitkarntakul P, Dhaun N, Melville V, et al. Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co-morbidity. Atherosclerosis 2011; 216: 217-225
-
(2011)
Atherosclerosis
, vol.216
, pp. 217-225
-
-
Lilitkarntakul, P.1
Dhaun, N.2
Melville, V.3
-
55
-
-
36749090703
-
Urinary excretion of endothelin-1 (et-1) transforming growth factor-beta1 (tgf-beta1) and vascular endothelial growth factor (vegf165) in paediatric chronic kidney diseases: Results of the escape trial
-
Grenda R, Wuhl E, Litwin M, et al. Urinary excretion of endothelin-1 (ET-1), transforming growth factor-beta1 (TGF-beta1) and vascular endothelial growth factor (VEGF165) in paediatric chronic kidney diseases: results of the ESCAPE trial. Nephrol Dial Transplant 2007; 22: 3487-3494
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 3487-3494
-
-
Grenda, R.1
Wuhl, E.2
Litwin, M.3
-
56
-
-
0031026198
-
Endothelins in the normal and diseased kidney
-
Kohan D. Endothelins in the normal and diseased kidney. Am J Kidney Dis 1997; 29: 2-26
-
(1997)
Am J Kidney Dis
, vol.29
, pp. 2-26
-
-
Kohan, D.1
-
57
-
-
77949541141
-
Amelioration of metabolic acidosis in patients with low gfr reduced kidney endothelin production and kidney injury, and better preserved gfr
-
Phisitkul S, Khanna A, Simoni J, et al. Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR. Kidney Int 2010; 77: 617-623
-
(2010)
Kidney Int
, vol.77
, pp. 617-623
-
-
Phisitkul, S.1
Khanna, A.2
Simoni, J.3
-
58
-
-
77954757756
-
Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy
-
Mahajan A, Simoni J, Sheather SJ, et al. Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy. Kidney Int 2010; 78: 303-309
-
(2010)
Kidney Int
, vol.78
, pp. 303-309
-
-
Mahajan, A.1
Simoni, J.2
Sheather, S.J.3
-
59
-
-
84867114046
-
Role of endothelin-1 in renal regulation of acid-base equilibrium in acidotic humans
-
Pallini A, Hulter HN, Muser J, et al. Role of endothelin-1 in renal regulation of acid-base equilibrium in acidotic humans. Am J Physiol Renal Physiol 2012; 303: F991-F999
-
(2012)
Am J Physiol Renal Physiol
, vol.303
, pp. F991-F999
-
-
Pallini, A.1
Hulter, H.N.2
Muser, J.3
-
60
-
-
1542514709
-
Endothelin-A receptor antagonism reduces blood pressure and increases renal blood flow in hypertensive patients with chronic renal failure: A comparison of selective and combined endothelin receptor blockade
-
Goddard J, Johnston NR, Hand MF, et al. Endothelin-A receptor antagonism reduces blood pressure and increases renal blood flow in hypertensive patients with chronic renal failure: a comparison of selective and combined endothelin receptor blockade. Circulation 2004; 109: 1186-1193
-
(2004)
Circulation
, vol.109
, pp. 1186-1193
-
-
Goddard, J.1
Johnston, N.R.2
Hand, M.F.3
-
61
-
-
67649859521
-
Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-A receptor antagonism in chronic kidney disease
-
Dhaun N, Macintyre IM, Melville V, et al. Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-A receptor antagonism in chronic kidney disease. Hypertension 2009; 54: 113-119
-
(2009)
Hypertension
, vol.54
, pp. 113-119
-
-
Dhaun, N.1
MacIntyre, I.M.2
Melville, V.3
-
62
-
-
70349241843
-
Effects of endothelin receptor antagonism relate to the degree of renin-Angiotensin system blockade in chronic proteinuric kidney disease
-
Dhaun N, Macintyre IM, Melville V, et al. Effects of endothelin receptor antagonism relate to the degree of renin-Angiotensin system blockade in chronic proteinuric kidney disease. Hypertension 2009; 54: e19-e20
-
(2009)
Hypertension
, vol.54
, pp. e19-e20
-
-
Dhaun, N.1
MacIntyre, I.M.2
Melville, V.3
-
63
-
-
36749089567
-
Haemodynamic and renal effects of endothelin receptor antagonism in patients with chronic kidney disease
-
Dhaun N, Ferro CJ, Davenport AP, et al. Haemodynamic and renal effects of endothelin receptor antagonism in patients with chronic kidney disease. Nephrol Dial Transplant 2007; 22: 3228-3234
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 3228-3234
-
-
Dhaun, N.1
Ferro, C.J.2
Davenport, A.P.3
-
64
-
-
62149126622
-
Avosentan reduces albumin excretion in diabetics with macroalbuminuria
-
Wenzel RR, Littke T, Kuranoff S, et al. Avosentan reduces albumin excretion in diabetics with macroalbuminuria. J Am Soc Nephrol 2009; 20: 655-664
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 655-664
-
-
Wenzel, R.R.1
Littke, T.2
Kuranoff, S.3
-
65
-
-
77949877308
-
Avosentan for overt diabetic nephropathy
-
Mann JF, Green D, Jamerson K, et al. Avosentan for overt diabetic nephropathy. J Am Soc Nephrol 2010; 21: 527-535
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 527-535
-
-
Mann, J.F.1
Green, D.2
Jamerson, K.3
-
66
-
-
67349246506
-
Dose-dependent acute and sustained renal effects of the endothelin receptor antagonist avosentan in healthy subjects
-
Smolander J, Vogt B, Maillard M, et al. Dose-dependent acute and sustained renal effects of the endothelin receptor antagonist avosentan in healthy subjects. Chin Pharmacol Ther 2009; 85: 628-634
-
(2009)
Chin Pharmacol Ther
, vol.85
, pp. 628-634
-
-
Smolander, J.1
Vogt, B.2
Maillard, M.3
-
67
-
-
79953213661
-
Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease
-
Dhaun N, Macintyre IM, Kerr D, et al. Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease. Hypertension 2011; 57: 772-779
-
(2011)
Hypertension
, vol.57
, pp. 772-779
-
-
Dhaun, N.1
MacIntyre, I.M.2
Kerr, D.3
-
68
-
-
79953295959
-
Addition of atrasentan to renin-Angiotensin system blockade reduces albuminuria in diabetic nephropathy
-
Kohan DE, Pritchett Y, Molitch M, et al. Addition of atrasentan to renin-Angiotensin system blockade reduces albuminuria in diabetic nephropathy. J Am Soc Nephrol 2011; 22: 763-772
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 763-772
-
-
Kohan, D.E.1
Pritchett, Y.2
Molitch, M.3
-
69
-
-
84867418316
-
Clinical efficacy of the selective endothelin A receptor antagonist, atrasentan, in patients with diabetes and chronic kidney disease (CKD
-
Andress DL, Coll B, Pritchett Y, et al. Clinical efficacy of the selective endothelin A receptor antagonist, atrasentan, in patients with diabetes and chronic kidney disease (CKD). Life Sci 2012; 91: 739-742
-
(2012)
Life Sci
, vol.91
, pp. 739-742
-
-
Andress, D.L.1
Coll, B.2
Pritchett, Y.3
-
70
-
-
84906540059
-
The endothelin antagonist atrasentan lowers residual albuminuria in type 2 diabetic patients with nephropathy
-
in press
-
De Zeeuw D, Coll B, Andress D, et al. The endothelin antagonist atrasentan lowers residual albuminuria in type 2 diabetic patients with nephropathy. J Am Soc Nephrol 2014 (in press
-
(2014)
J Am Soc Nephrol
-
-
De Zeeuw, D.1
Coll, B.2
Andress, D.3
-
71
-
-
84882597884
-
Effect on blood pressure of combined inhibition of endothelin-converting enzyme and neutral endopeptidase with daglutril in patients with type 2 diabetes who have albuminuria: A randomised, crossover, double-blind, placebo-controlled trial
-
Parvanova A, Van Der Meer I, Iliev I, et al. Effect on blood pressure of combined inhibition of endothelin-converting enzyme and neutral endopeptidase with daglutril in patients with type 2 diabetes who have albuminuria: a randomised, crossover, double-blind, placebo-controlled trial. Lancet Diabetes Endocrinol 2013; 1: 19-27
-
(2013)
Lancet Diabetes Endocrinol
, vol.1
, pp. 19-27
-
-
Parvanova, A.1
Van Der Meer, I.2
Iliev, I.3
-
75
-
-
79551550855
-
An open label trial of the endothelin receptor antagonist bosentan in scleroderma renal crisis (BIRD-1
-
abstract
-
Penn H, Burns A, Black C, et al. An open label trial of the endothelin receptor antagonist bosentan in scleroderma renal crisis (BIRD-1). Arthritis Rheum 2009; 60 Suppl 10: 451 (abstract
-
(2009)
Arthritis Rheum
, vol.60
, pp. 451
-
-
Penn, H.1
Burns, A.2
Black, C.3
-
76
-
-
84855474159
-
Endothelin antagonists in clinical trials: Lessons learned
-
Barton M, Kohan DE. Endothelin antagonists in clinical trials: lessons learned. Contrib Nephrol 2011; 172: 255-260
-
(2011)
Contrib Nephrol
, vol.172
, pp. 255-260
-
-
Barton, M.1
Kohan, D.E.2
-
77
-
-
84867578602
-
Clinical trials with endothelin receptor antagonists: What went wrong and where can we improve
-
Kohan DE, Cleland JG, Rubin LJ, et al. Clinical trials with endothelin receptor antagonists: what went wrong and where can we improve? Life Sci 2012; 91: 528-539
-
(2012)
Life Sci
, vol.91
, pp. 528-539
-
-
Kohan, D.E.1
Cleland, J.G.2
Rubin, L.J.3
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