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Volumn 1842, Issue 10, 2014, Pages 1971-1980

Protein-protein interactions and genetic diseases: The interactome

Author keywords

Complex human disease; Genetics and proteomics; Protein protein interaction

Indexed keywords

FIBROBLAST GROWTH FACTOR;

EID: 84908371409     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.05.028     Document Type: Review
Times cited : (91)

References (98)
  • 1
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander E.S., et al. Initial sequencing and analysis of the human genome. Nature 2001, 409:860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1
  • 2
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter J.C., et al. The sequence of the human genome. Science 2001, 291:1304-1351.
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1
  • 3
    • 77956331627 scopus 로고    scopus 로고
    • Integrating common and rare genetic variation in diverse human populations
    • Altshuler D.M., et al. Integrating common and rare genetic variation in diverse human populations. Nature 2010, 467:52-58.
    • (2010) Nature , vol.467 , pp. 52-58
    • Altshuler, D.M.1
  • 4
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • Abecasis G.R., et al. A map of human genome variation from population-scale sequencing. Nature 2010, 467:1061-1073.
    • (2010) Nature , vol.467 , pp. 1061-1073
    • Abecasis, G.R.1
  • 5
    • 34748848639 scopus 로고    scopus 로고
    • The NCBI dbGaP database of genotypes and phenotypes
    • Mailman M.D., et al. The NCBI dbGaP database of genotypes and phenotypes. Nat. Genet. 2007, 39:1181-1186.
    • (2007) Nat. Genet. , vol.39 , pp. 1181-1186
    • Mailman, M.D.1
  • 6
    • 55449120805 scopus 로고    scopus 로고
    • Genetic mapping in human disease
    • Altshuler D., Daly M.J., Lander E.S. Genetic mapping in human disease. Science 2008, 322:881-888.
    • (2008) Science , vol.322 , pp. 881-888
    • Altshuler, D.1    Daly, M.J.2    Lander, E.S.3
  • 7
    • 80052855150 scopus 로고    scopus 로고
    • Next-generation human genetics
    • Shendure J. Next-generation human genetics. Genome Biol. 2011, 12:408.
    • (2011) Genome Biol. , vol.12 , pp. 408
    • Shendure, J.1
  • 8
    • 0742305866 scopus 로고    scopus 로고
    • Network biology: understanding the cell's functional organization
    • Barabasi A.L., Oltvai Z.N. Network biology: understanding the cell's functional organization. Nat. Rev. Genet. 2004, 5:101-113.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 101-113
    • Barabasi, A.L.1    Oltvai, Z.N.2
  • 9
    • 78650373804 scopus 로고    scopus 로고
    • Network medicine: a network-based approach to human disease
    • Barabasi A.L., Gulbahce N., Loscalzo J. Network medicine: a network-based approach to human disease. Nat. Rev. Genet. 2011, 12:56-68.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 56-68
    • Barabasi, A.L.1    Gulbahce, N.2    Loscalzo, J.3
  • 10
    • 84860712363 scopus 로고    scopus 로고
    • Patterns and rates of exonic de novo mutations in autism spectrum disorders
    • Neale B.M., et al. Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature 2012, 485:242-245.
    • (2012) Nature , vol.485 , pp. 242-245
    • Neale, B.M.1
  • 11
    • 84860741138 scopus 로고    scopus 로고
    • Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
    • O'Roak B.J., et al. Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature 2012, 485:246-250.
    • (2012) Nature , vol.485 , pp. 246-250
    • O'Roak, B.J.1
  • 12
    • 80052325959 scopus 로고    scopus 로고
    • Pervasive sharing of genetic effects in autoimmune disease
    • Cotsapas C., et al. Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet. 2011, 7:e1002254.
    • (2011) PLoS Genet. , vol.7 , pp. e1002254
    • Cotsapas, C.1
  • 13
    • 79851502150 scopus 로고    scopus 로고
    • Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology
    • Rossin E.J., et al. Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet. 2011, 7:e1001273.
    • (2011) PLoS Genet. , vol.7 , pp. e1001273
    • Rossin, E.J.1
  • 14
    • 46349086693 scopus 로고    scopus 로고
    • Integrative analysis for finding genes and networks involved in diabetes and other complex diseases
    • Bergholdt R., et al. Integrative analysis for finding genes and networks involved in diabetes and other complex diseases. Genome Biol. 2007, 8:R253.
    • (2007) Genome Biol. , vol.8 , pp. R253
    • Bergholdt, R.1
  • 15
    • 58549101103 scopus 로고    scopus 로고
    • A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes
    • Lage K., et al. A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:20870-20875.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 20870-20875
    • Lage, K.1
  • 16
    • 33947095027 scopus 로고    scopus 로고
    • A human phenome-interactome network of protein complexes implicated in genetic disorders
    • Lage K., et al. A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat. Biotechnol. 2007, 25:309-316.
    • (2007) Nat. Biotechnol. , vol.25 , pp. 309-316
    • Lage, K.1
  • 17
    • 84859526125 scopus 로고    scopus 로고
    • Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression
    • Bergholdt R., et al. Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression. Diabetes 2012, 61:954-962.
    • (2012) Diabetes , vol.61 , pp. 954-962
    • Bergholdt, R.1
  • 18
    • 80053074286 scopus 로고    scopus 로고
    • Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis
    • Berchtold L.A., et al. Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:E681-E688.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. E681-E688
    • Berchtold, L.A.1
  • 19
    • 84863010950 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of protein networks provides insight into human genetic disease
    • Wang X., et al. Three-dimensional reconstruction of protein networks provides insight into human genetic disease. Nat. Biotechnol. 2012, 30:159-164.
    • (2012) Nat. Biotechnol. , vol.30 , pp. 159-164
    • Wang, X.1
  • 20
    • 84857780876 scopus 로고    scopus 로고
    • Evidence for network evolution in an Arabidopsis interactome map
    • Evidence for network evolution in an Arabidopsis interactome map. Science 2011, 333:601-607.
    • (2011) Science , vol.333 , pp. 601-607
  • 21
    • 0035836765 scopus 로고    scopus 로고
    • A comprehensive two-hybrid analysis to explore the yeast protein interactome
    • Ito T., et al. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:4569-4574.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 4569-4574
    • Ito, T.1
  • 22
    • 0034628508 scopus 로고    scopus 로고
    • A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
    • Uetz P., et al. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 2000, 403:623-627.
    • (2000) Nature , vol.403 , pp. 623-627
    • Uetz, P.1
  • 23
    • 0037050004 scopus 로고    scopus 로고
    • Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
    • Ho Y., et al. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 2002, 415:180-183.
    • (2002) Nature , vol.415 , pp. 180-183
    • Ho, Y.1
  • 24
    • 0037050026 scopus 로고    scopus 로고
    • Functional organization of the yeast proteome by systematic analysis of protein complexes
    • Gavin A.C., et al. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 2002, 415:141-147.
    • (2002) Nature , vol.415 , pp. 141-147
    • Gavin, A.C.1
  • 25
    • 33644555054 scopus 로고    scopus 로고
    • Proteome survey reveals modularity of the yeast cell machinery
    • Gavin A.C., et al. Proteome survey reveals modularity of the yeast cell machinery. Nature 2006, 440:631-636.
    • (2006) Nature , vol.440 , pp. 631-636
    • Gavin, A.C.1
  • 26
    • 33645453254 scopus 로고    scopus 로고
    • Global landscape of protein complexes in the yeast Saccharomyces cerevisiae
    • Krogan N.J., et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 2006, 440:637-643.
    • (2006) Nature , vol.440 , pp. 637-643
    • Krogan, N.J.1
  • 27
    • 45849110261 scopus 로고    scopus 로고
    • An in vivo map of the yeast protein interactome
    • Tarassov K., et al. An in vivo map of the yeast protein interactome. Science 2008, 320:1465-1470.
    • (2008) Science , vol.320 , pp. 1465-1470
    • Tarassov, K.1
  • 28
    • 9144264169 scopus 로고    scopus 로고
    • A map of the interactome network of the metazoan C. elegans
    • Li S., et al. A map of the interactome network of the metazoan C. elegans. Science 2004, 303:540-543.
    • (2004) Science , vol.303 , pp. 540-543
    • Li, S.1
  • 29
    • 0345600247 scopus 로고    scopus 로고
    • A protein interaction map of Drosophila melanogaster
    • Giot L., et al. A protein interaction map of Drosophila melanogaster. Science 2003, 302:1727-1736.
    • (2003) Science , vol.302 , pp. 1727-1736
    • Giot, L.1
  • 30
    • 80155171417 scopus 로고    scopus 로고
    • A protein complex network of Drosophila melanogaster
    • Guruharsha K.G., et al. A protein complex network of Drosophila melanogaster. Cell 2011, 147:690-703.
    • (2011) Cell , vol.147 , pp. 690-703
    • Guruharsha, K.G.1
  • 31
    • 27144530248 scopus 로고    scopus 로고
    • Towards a proteome-scale map of the human protein-protein interaction network
    • Rual J.F., et al. Towards a proteome-scale map of the human protein-protein interaction network. Nature 2005, 437:1173-1178.
    • (2005) Nature , vol.437 , pp. 1173-1178
    • Rual, J.F.1
  • 32
    • 25144498379 scopus 로고    scopus 로고
    • A human protein-protein interaction network: a resource for annotating the proteome
    • Stelzl U., et al. A human protein-protein interaction network: a resource for annotating the proteome. Cell 2005, 122:957-968.
    • (2005) Cell , vol.122 , pp. 957-968
    • Stelzl, U.1
  • 33
    • 33947219266 scopus 로고    scopus 로고
    • Large-scale mapping of human protein-protein interactions by mass spectrometry
    • Ewing R.M., et al. Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol. Syst. Biol. 2007, 3:89.
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 89
    • Ewing, R.M.1
  • 34
    • 84865677098 scopus 로고    scopus 로고
    • A census of human soluble protein complexes
    • Havugimana P.C., et al. A census of human soluble protein complexes. Cell 2012, 150:1068-1081.
    • (2012) Cell , vol.150 , pp. 1068-1081
    • Havugimana, P.C.1
  • 35
    • 79957575162 scopus 로고    scopus 로고
    • Analysis of the human endogenous coregulator complexome
    • Malovannaya A., et al. Analysis of the human endogenous coregulator complexome. Cell 2011, 145:787-799.
    • (2011) Cell , vol.145 , pp. 787-799
    • Malovannaya, A.1
  • 36
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interactions
    • Fields S., Song O. A novel genetic system to detect protein-protein interactions. Nature 1989, 340:245-246.
    • (1989) Nature , vol.340 , pp. 245-246
    • Fields, S.1    Song, O.2
  • 37
    • 84862703457 scopus 로고    scopus 로고
    • Interactome mapping for analysis of complex phenotypes: insights from benchmarking binary interaction assays
    • Braun P. Interactome mapping for analysis of complex phenotypes: insights from benchmarking binary interaction assays. Proteomics 2012, 12:1499-1518.
    • (2012) Proteomics , vol.12 , pp. 1499-1518
    • Braun, P.1
  • 38
    • 79551517793 scopus 로고    scopus 로고
    • Recent advances in charting protein-protein interaction: mass spectrometry-based approaches
    • Gavin A.C., Maeda K., Kuhner S. Recent advances in charting protein-protein interaction: mass spectrometry-based approaches. Curr. Opin. Biotechnol. 2011, 22:42-49.
    • (2011) Curr. Opin. Biotechnol. , vol.22 , pp. 42-49
    • Gavin, A.C.1    Maeda, K.2    Kuhner, S.3
  • 39
    • 0037161731 scopus 로고    scopus 로고
    • Comparative assessment of large-scale data sets of protein-protein interactions
    • von Mering C., et al. Comparative assessment of large-scale data sets of protein-protein interactions. Nature 2002, 417:399-403.
    • (2002) Nature , vol.417 , pp. 399-403
    • von Mering, C.1
  • 40
    • 53349156368 scopus 로고    scopus 로고
    • Biochemistry. Not comparable, but complementary
    • Jensen L.J., Bork P. Biochemistry. Not comparable, but complementary. Science 2008, 322:56-57.
    • (2008) Science , vol.322 , pp. 56-57
    • Jensen, L.J.1    Bork, P.2
  • 41
    • 0036789265 scopus 로고    scopus 로고
    • Analyzing yeast protein-protein interaction data obtained from different sources
    • Bader G.D., Hogue C.W. Analyzing yeast protein-protein interaction data obtained from different sources. Nat. Biotechnol. 2002, 20:991-997.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 991-997
    • Bader, G.D.1    Hogue, C.W.2
  • 42
    • 53349117774 scopus 로고    scopus 로고
    • High-quality binary protein interaction map of the yeast interactome network
    • Yu H., et al. High-quality binary protein interaction map of the yeast interactome network. Science 2008, 322:104-110.
    • (2008) Science , vol.322 , pp. 104-110
    • Yu, H.1
  • 43
    • 78650274124 scopus 로고    scopus 로고
    • New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size
    • Sambourg L., Thierry-Mieg N. New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size. BMC Bioinforma. 2010, 11:605.
    • (2010) BMC Bioinforma. , vol.11 , pp. 605
    • Sambourg, L.1    Thierry-Mieg, N.2
  • 44
    • 84865556443 scopus 로고    scopus 로고
    • Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development
    • Lage K., et al. Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:14035-14040.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 14035-14040
    • Lage, K.1
  • 45
    • 64349094767 scopus 로고    scopus 로고
    • Tissue specificity and the human protein interaction network
    • Bossi A., Lehner B. Tissue specificity and the human protein interaction network. Mol. Syst. Biol. 2009, 5:260.
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 260
    • Bossi, A.1    Lehner, B.2
  • 46
    • 58149305794 scopus 로고    scopus 로고
    • An empirical framework for binary interactome mapping
    • Venkatesan K., et al. An empirical framework for binary interactome mapping. Nat. Methods 2009, 6:83-90.
    • (2009) Nat. Methods , vol.6 , pp. 83-90
    • Venkatesan, K.1
  • 47
    • 44349113144 scopus 로고    scopus 로고
    • Estimating the size of the human interactome
    • Stumpf M.P., et al. Estimating the size of the human interactome. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:6959-6964.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 6959-6964
    • Stumpf, M.P.1
  • 48
    • 84875700843 scopus 로고    scopus 로고
    • Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS
    • Varjosalo M., et al. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. Nat. Methods 2013, 10:307-314.
    • (2013) Nat. Methods , vol.10 , pp. 307-314
    • Varjosalo, M.1
  • 50
    • 58149193222 scopus 로고    scopus 로고
    • Human Protein Reference Database - 2009 update
    • Keshava Prasad T.S., et al. Human Protein Reference Database - 2009 update. Nucleic Acids Res. 2009, 37:D767-D772.
    • (2009) Nucleic Acids Res. , vol.37 , pp. D767-D772
    • Keshava Prasad, T.S.1
  • 51
    • 0036088133 scopus 로고    scopus 로고
    • DIP, the database of interacting proteins: a research tool for studying cellular networks of protein interactions
    • Xenarios I., et al. DIP, the database of interacting proteins: a research tool for studying cellular networks of protein interactions. Nucleic Acids Res. 2002, 30:303-305.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 303-305
    • Xenarios, I.1
  • 52
    • 84859204939 scopus 로고    scopus 로고
    • The IntAct molecular interaction database in 2012
    • Kerrien S., et al. The IntAct molecular interaction database in 2012. Nucleic Acids Res. 2012, 40:D841-D846.
    • (2012) Nucleic Acids Res. , vol.40 , pp. D841-D846
    • Kerrien, S.1
  • 53
    • 75549083295 scopus 로고    scopus 로고
    • MINT, the molecular interaction database: 2009 update
    • Ceol A., et al. MINT, the molecular interaction database: 2009 update. Nucleic Acids Res. 2010, 38:D532-D539.
    • (2010) Nucleic Acids Res. , vol.38 , pp. D532-D539
    • Ceol, A.1
  • 55
    • 48249112175 scopus 로고    scopus 로고
    • MPIDB: the microbial protein interaction database
    • Goll J., et al. MPIDB: the microbial protein interaction database. Bioinformatics 2008, 24:1743-1744.
    • (2008) Bioinformatics , vol.24 , pp. 1743-1744
    • Goll, J.1
  • 56
    • 84876581893 scopus 로고    scopus 로고
    • InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation
    • Breuer K., et al. InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucleic Acids Res. 2013, 41:D1228-D1233.
    • (2013) Nucleic Acids Res. , vol.41 , pp. D1228-D1233
    • Breuer, K.1
  • 57
    • 75249101080 scopus 로고    scopus 로고
    • Evaluation of linguistic features useful in extraction of interactions from PubMed; application to annotating known, high-throughput and predicted interactions in I2D
    • Niu Y., Otasek D., Jurisica I. Evaluation of linguistic features useful in extraction of interactions from PubMed; application to annotating known, high-throughput and predicted interactions in I2D. Bioinformatics 2010, 26:111-119.
    • (2010) Bioinformatics , vol.26 , pp. 111-119
    • Niu, Y.1    Otasek, D.2    Jurisica, I.3
  • 58
    • 84859208501 scopus 로고    scopus 로고
    • Protein interaction data curation: the International Molecular Exchange (IMEx) consortium
    • Orchard S., et al. Protein interaction data curation: the International Molecular Exchange (IMEx) consortium. Nat. Methods 2012, 9:345-350.
    • (2012) Nat. Methods , vol.9 , pp. 345-350
    • Orchard, S.1
  • 59
    • 79952676403 scopus 로고    scopus 로고
    • Literature curation of protein interactions: measuring agreement across major public databases
    • (baq026 (2010))
    • Turinsky A.L., Razick S., Turner B., Donaldson I.M., Wodak S.J. Literature curation of protein interactions: measuring agreement across major public databases. Database (Oxf.) 2010, (baq026 (2010)).
    • (2010) Database (Oxf.)
    • Turinsky, A.L.1    Razick, S.2    Turner, B.3    Donaldson, I.M.4    Wodak, S.J.5
  • 60
    • 58149213932 scopus 로고    scopus 로고
    • Literature-curated protein interaction datasets
    • Cusick M.E., et al. Literature-curated protein interaction datasets. Nat. Methods 2009, 6:39-46.
    • (2009) Nat. Methods , vol.6 , pp. 39-46
    • Cusick, M.E.1
  • 61
    • 73349085604 scopus 로고    scopus 로고
    • Recurated protein interaction datasets
    • Salwinski L., et al. Recurated protein interaction datasets. Nat. Methods 2009, 6:860-861.
    • (2009) Nat. Methods , vol.6 , pp. 860-861
    • Salwinski, L.1
  • 62
    • 84876515907 scopus 로고    scopus 로고
    • STRING v9.1: protein-protein interaction networks, with increased coverage and integration
    • Franceschini A., et al. STRING v9.1: protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res. 2013, 41:D808-D815.
    • (2013) Nucleic Acids Res. , vol.41 , pp. D808-D815
    • Franceschini, A.1
  • 63
    • 33646030274 scopus 로고    scopus 로고
    • A wiring of the human nucleolus
    • Hinsby A.M., et al. A wiring of the human nucleolus. Mol. Cell 2006, 22:285-295.
    • (2006) Mol. Cell , vol.22 , pp. 285-295
    • Hinsby, A.M.1
  • 64
    • 77954016586 scopus 로고    scopus 로고
    • Dissecting spatio-temporal protein networks driving human heart development and related disorders
    • Lage K., et al. Dissecting spatio-temporal protein networks driving human heart development and related disorders. Mol. Syst. Biol. 2010, 6:381.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 381
    • Lage, K.1
  • 65
    • 84877260745 scopus 로고    scopus 로고
    • Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism
    • Miraoui H., et al. Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. Am. J. Hum. Genet. 2013, 92:725-743.
    • (2013) Am. J. Hum. Genet. , vol.92 , pp. 725-743
    • Miraoui, H.1
  • 66
    • 34250743173 scopus 로고    scopus 로고
    • Systematic discovery of in vivo phosphorylation networks
    • Linding R., et al. Systematic discovery of in vivo phosphorylation networks. Cell 2007, 129:1415-1426.
    • (2007) Cell , vol.129 , pp. 1415-1426
    • Linding, R.1
  • 67
    • 84883575046 scopus 로고    scopus 로고
    • GeneMANIA prediction server 2013 update
    • Zuberi K., et al. GeneMANIA prediction server 2013 update. Nucleic Acids Res. 2013, 41:W115-W122.
    • (2013) Nucleic Acids Res. , vol.41 , pp. W115-W122
    • Zuberi, K.1
  • 68
    • 84891781481 scopus 로고    scopus 로고
    • FunCoup 3.0: database of genome-wide functional coupling networks
    • Schmitt T., Ogris C., Sonnhammer E.L. FunCoup 3.0: database of genome-wide functional coupling networks. Nucleic Acids Res. 2014, 42(Database issue):D380-D388.
    • (2014) Nucleic Acids Res. , vol.42 , Issue.Database issue , pp. D380-D388
    • Schmitt, T.1    Ogris, C.2    Sonnhammer, E.L.3
  • 71
    • 84881455143 scopus 로고    scopus 로고
    • Mentha: a resource for browsing integrated protein-interaction networks
    • Calderone A., Castagnoli L., Cesareni G. Mentha: a resource for browsing integrated protein-interaction networks. Nat. Methods 2013, 10:690-691.
    • (2013) Nat. Methods , vol.10 , pp. 690-691
    • Calderone, A.1    Castagnoli, L.2    Cesareni, G.3
  • 75
    • 77955480278 scopus 로고    scopus 로고
    • Revisiting date and party hubs: novel approaches to role assignment in protein interaction networks
    • Agarwal S., Deane C.M., Porter M.A., Jones N.S. Revisiting date and party hubs: novel approaches to role assignment in protein interaction networks. PLoS Comput. Biol. 2010, 6(6):e1000817.
    • (2010) PLoS Comput. Biol. , vol.6 , Issue.6 , pp. e1000817
    • Agarwal, S.1    Deane, C.M.2    Porter, M.A.3    Jones, N.S.4
  • 76
    • 0032482432 scopus 로고    scopus 로고
    • Collective dynamics of 'small-world' networks
    • Watts D.J., Strogatz S.H. Collective dynamics of 'small-world' networks. Nature 1998, 393:440-442.
    • (1998) Nature , vol.393 , pp. 440-442
    • Watts, D.J.1    Strogatz, S.H.2
  • 78
    • 33747035889 scopus 로고    scopus 로고
    • Predicting disease genes using protein-protein interactions
    • Oti M., Snel B., Huynen M.A., Brunner H.G. Predicting disease genes using protein-protein interactions. J. Med. Genet. 2006, 43(8):691-698.
    • (2006) J. Med. Genet. , vol.43 , Issue.8 , pp. 691-698
    • Oti, M.1    Snel, B.2    Huynen, M.A.3    Brunner, H.G.4
  • 79
    • 84863987708 scopus 로고    scopus 로고
    • Computational tools for prioritizing candidate genes: boosting disease gene discovery
    • Moreau Y., Tranchevent L.C. Computational tools for prioritizing candidate genes: boosting disease gene discovery. Nat. Rev. Genet. 2012, 13(8):523-536.
    • (2012) Nat. Rev. Genet. , vol.13 , Issue.8 , pp. 523-536
    • Moreau, Y.1    Tranchevent, L.C.2
  • 81
    • 77957342306 scopus 로고    scopus 로고
    • Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits
    • Segrè A.V., DIAGRAM Consortium, MAGIC investigators, Groop L., Mootha V.K., Daly M.J., Altshuler D. Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PLoS Genet. 2010, 6(8).
    • (2010) PLoS Genet. , vol.6 , Issue.8
    • Segrè, A.V.1    Groop, L.2    Mootha, V.K.3    Daly, M.J.4    Altshuler, D.5
  • 82
    • 33646884801 scopus 로고    scopus 로고
    • Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes
    • Franke L., et al. Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes. Am. J. Hum. Genet. 2006, 78:1011-1025.
    • (2006) Am. J. Hum. Genet. , vol.78 , pp. 1011-1025
    • Franke, L.1
  • 83
    • 33646568805 scopus 로고    scopus 로고
    • Gene prioritization through genomic data fusion
    • Aerts S., et al. Gene prioritization through genomic data fusion. Nat. Biotechnol. 2006, 24:537-544.
    • (2006) Nat. Biotechnol. , vol.24 , pp. 537-544
    • Aerts, S.1
  • 85
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • Morris A.P., et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. 2012, 44:981-990.
    • (2012) Nat. Genet. , vol.44 , pp. 981-990
    • Morris, A.P.1
  • 86
    • 74249100674 scopus 로고    scopus 로고
    • Genome-wide association data reveal a global map of genetic interactions among protein complexes
    • Hannum G., Srivas R., Guénolé A., van Attikum H., Krogan N.J., Karp R.M., Ideker T. Genome-wide association data reveal a global map of genetic interactions among protein complexes. PLoS Genet. 2009, 5(12):e1000782.
    • (2009) PLoS Genet. , vol.5 , Issue.12 , pp. e1000782
    • Hannum, G.1    Srivas, R.2    Guénolé, A.3    van Attikum, H.4    Krogan, N.J.5    Karp, R.M.6    Ideker, T.7
  • 87
    • 84864402194 scopus 로고    scopus 로고
    • Leveraging models of cell regulation and GWAS data in integrative network-based association studies
    • Califano A., Butte A.J., Friend S., Ideker T., Schadt E. Leveraging models of cell regulation and GWAS data in integrative network-based association studies. Nat. Genet. 2012, 44(8):841-847.
    • (2012) Nat. Genet. , vol.44 , Issue.8 , pp. 841-847
    • Califano, A.1    Butte, A.J.2    Friend, S.3    Ideker, T.4    Schadt, E.5
  • 88
    • 84885018609 scopus 로고    scopus 로고
    • Systematic identification of trans eQTLs as putative drivers of known disease associations
    • Westra H.J., et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat. Genet. 2013, 45:1238-1243.
    • (2013) Nat. Genet. , vol.45 , pp. 1238-1243
    • Westra, H.J.1
  • 89
    • 84879879014 scopus 로고    scopus 로고
    • Variation and genetic control of protein abundance in humans
    • Wu L., et al. Variation and genetic control of protein abundance in humans. Nature 2013, 499:79-82.
    • (2013) Nature , vol.499 , pp. 79-82
    • Wu, L.1
  • 91
    • 84870529525 scopus 로고    scopus 로고
    • Diverse types of genetic variation converge on functional gene networks involved in schizophrenia
    • Gilman S.R., Chang J., Xu B., Bawa T.S., Gogos J.A., Karayiorgou M., Vitkup D. Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. Nat. Neurosci. 2012, 15(12):1723-1728.
    • (2012) Nat. Neurosci. , vol.15 , Issue.12 , pp. 1723-1728
    • Gilman, S.R.1    Chang, J.2    Xu, B.3    Bawa, T.S.4    Gogos, J.A.5    Karayiorgou, M.6    Vitkup, D.7
  • 92
    • 84856009926 scopus 로고    scopus 로고
    • Vif hijacks CBF-beta to degrade APOBEC3G and promote HIV-1 infection
    • Jager S., et al. Vif hijacks CBF-beta to degrade APOBEC3G and promote HIV-1 infection. Nature 2012, 481:371-375.
    • (2012) Nature , vol.481 , pp. 371-375
    • Jager, S.1
  • 96
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • Bernstein B.E., et al. An integrated encyclopedia of DNA elements in the human genome. Nature 2012, 489:57-74.
    • (2012) Nature , vol.489 , pp. 57-74
    • Bernstein, B.E.1
  • 97
    • 33845364320 scopus 로고    scopus 로고
    • Bioinformatics in the human interactome project
    • Ideker T., Valencia A. Bioinformatics in the human interactome project. Bioinformatics 2006, 22:2973-2974.
    • (2006) Bioinformatics , vol.22 , pp. 2973-2974
    • Ideker, T.1    Valencia, A.2
  • 98
    • 84873086126 scopus 로고    scopus 로고
    • Chromatin marks identify critical cell types for fine mapping complex trait variants
    • Trynka G., et al. Chromatin marks identify critical cell types for fine mapping complex trait variants. Nat. Genet. 2013, 45:124-130.
    • (2013) Nat. Genet. , vol.45 , pp. 124-130
    • Trynka, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.