Targeted suppression of EVI1 oncogene expression by sequence-specific Pyrrole-imidazole polyamide

Chemistry and Biology

Volumn 21, Issue 10, 2014, Pages 1370-1380

  Syed, Junetha ^a   Pandian, Ganesh N ^b   Sato, Shinsuke ^b   Taniguchi, Junichi ^a   Chandran, Anandhakumar ^a   Hashiya, Kaori ^a   Bando, Toshikazu ^a   Sugiyama, Hiroshi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ECTOPIC VIRAL INTEGRATION SITE 1 TRANSCRIPTION FACTOR; ONCOPROTEIN; POLYAMIDE; PYRROLE IMIDAZOLE POLYAMIDE 1; PYRROLE IMIDAZOLE POLYAMIDE 2; PYRROLE IMIDAZOLE POLYAMIDE 3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR REL; TRANSCRIPTOME; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; ELK1 PROTEIN, HUMAN; IMIDAZOLE; IMIDAZOLE DERIVATIVE; MECOM PROTEIN, HUMAN; MESSENGER RNA; NYLON; PEPTIDE; PYRROLE DERIVATIVE; TRANSCRIPTION FACTOR ELK 1;

ARTICLE; BINDING SITE; BREAST CANCER CELL LINE; CANCER GENE THERAPY; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS INHIBITION; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN BINDING; TRANSCRIPTOMICS; ANTAGONISTS AND INHIBITORS; CELL MOTION; CHEMISTRY; DOWN REGULATION; DRUG EFFECTS; GENETICS; METABOLISM; PROTO ONCOGENE; TUMOR CELL LINE; UPREGULATION;

ANTINEOPLASTIC AGENTS; BINDING SITES; CELL LINE, TUMOR; CELL MOVEMENT; DNA-BINDING PROTEINS; DOWN-REGULATION; ETS-DOMAIN PROTEIN ELK-1; HUMANS; IMIDAZOLES; NYLONS; PEPTIDES; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-REL; PROTO-ONCOGENES; PYRROLES; RNA, MESSENGER; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 84908353273     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.07.019     Document Type: Article

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