Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing

Journal of the American Chemical Society

Volumn 134, Issue 42, 2012, Pages 17814-17822

  Meier, Jordan L ^a   Yu, Abigail S ^b,c   Korf, Ian ^b   Segal, David J ^c   Dervan, Peter B ^a  

^a California Institute of Technology   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY PURIFICATION; DNA BINDING SITE; DNA-BINDING; DNA-BINDING SPECIFICITY; GENOMIC APPLICATIONS; HAIRPIN POLYAMIDES; HIGH AFFINITY; HIGH-AFFINITY SITES; HIGH-THROUGHPUT ANALYSIS; HIGH-THROUGHPUT METHOD; MASSIVELY PARALLEL SEQUENCING; MINOR GROOVES; PYRROLE-IMIDAZOLE POLYAMIDES; REVERSE ORIENTATION;

AMIDES; BINDING SITES; DNA; MOLECULES; POLYAMIDES;

GENE ENCODING;

POLYAMIDE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA BINDING MOTIF; DNA HAIRPIN; DNA LIBRARY; DNA SEQUENCE; HIGH THROUGHPUT SEQUENCING; NANOBIOTECHNOLOGY; NUCLEOTIDE BINDING SITE; PARALLEL SEQUENCING; PREDICTION;

DNA; GENE LIBRARY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; IMIDAZOLES; NYLONS; PYRROLES;

EID: 84867801948     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja308888c     Document Type: Article

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