Complete Mapping of Substrate Translocation Highlights the Role of LeuT N-terminal Segment in Regulating Transport Cycle

PLoS Computational Biology

Volumn 10, Issue 10, 2014, Pages

  Cheng, Mary Hongying ^a   Bahar, Ivet ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; FACINGS; METAL IONS; MOLECULES; NEUROPHYSIOLOGY;

COMPLETE MAPPINGS; MECHANISTICS; N-TERMINALS; NEURONAL SIGNAL TRANSMISSION; SODIUM IONS; STRUCTURAL DATA; STRUCTURE-BASED; SUBSTRATE TRANSPORTS; SYMPORTERS; TRANSPORT CYCLE;

SODIUM;

AMINO ACID TRANSPORTER; LEUCINE TRANSPORTER; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; COTRANSPORTER; LEUCINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; BINDING SITE; EXTRACELLULAR SPACE; HYDRATION; INTRACELLULAR MEMBRANE; MOLECULAR DYNAMICS; POSTSYNAPTIC POTENTIAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; REGULATORY MECHANISM; SODIUM TRANSPORT; STRUCTURE ACTIVITY RELATION; BIOLOGICAL MODEL; BIOLOGY; CHEMISTRY; GENETICS; INTRACELLULAR SPACE; ION TRANSPORT; METABOLISM;

BACTERIAL PROTEINS; COMPUTATIONAL BIOLOGY; EXTRACELLULAR SPACE; INTRACELLULAR SPACE; ION TRANSPORT; LEUCINE; MODELS, BIOLOGICAL; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; SYMPORTERS;

EID: 84908333081     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003879     Document Type: Article

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