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Volumn 51, Issue 1-2, 1998, Pages 87-96

Neurotransmitter transporters as molecular targets for addictive drugs

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; AMPHETAMINE DERIVATIVE; CARRIER PROTEIN; CHLORIDE ION; COCAINE; DOPAMINE; GLUTAMIC ACID; MONOAMINE; NEUROTRANSMITTER; PSYCHOSTIMULANT AGENT; SODIUM ION;

EID: 0032104581     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-8716(98)00068-4     Document Type: Article
Times cited : (225)

References (76)
  • 1
    • 0027240164 scopus 로고
    • Neurotransmitter transporters: Three distinct gene families
    • Amara, S.G., Arriza, J.L., 1993. Neurotransmitter transporters: three distinct gene families. Curr. Opin. Neurobiol. 3, 337-344.
    • (1993) Curr. Opin. Neurobiol. , vol.3 , pp. 337-344
    • Amara, S.G.1    Arriza, J.L.2
  • 2
    • 0027446493 scopus 로고
    • Neurotransmitter transporters: Recent progress
    • Amara, S.G., Kuhar, M.J., 1993. Neurotransmitter transporters: recent progress. Ann. Rev. Neurosci. 16, 73-93.
    • (1993) Ann. Rev. Neurosci. , vol.16 , pp. 73-93
    • Amara, S.G.1    Kuhar, M.J.2
  • 4
    • 0029860223 scopus 로고    scopus 로고
    • Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter
    • Barker, E.L., Blakely, R.D., 1996. Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter. Mol. Pharmacol. 50, 957-965.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 957-965
    • Barker, E.L.1    Blakely, R.D.2
  • 5
    • 0028132193 scopus 로고
    • Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands
    • Barker, E.L., Kimmel, H.L., Blakely, R.D., 1994. Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands. Mol. Pharmacol. 46, 799-807.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 799-807
    • Barker, E.L.1    Kimmel, H.L.2    Blakely, R.D.3
  • 6
    • 0026419334 scopus 로고
    • Cloning and expression of a functional serotonin transporter from rat brain
    • Blakely, R.D., Berson, H.E., Fremeau, R.T., et al., 1991. Cloning and expression of a functional serotonin transporter from rat brain. Nature 354, 66-70.
    • (1991) Nature , vol.354 , pp. 66-70
    • Blakely, R.D.1    Berson, H.E.2    Fremeau, R.T.3
  • 7
    • 0030860528 scopus 로고    scopus 로고
    • Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter
    • Bossé, R., Fumagalli, F., Jaber, M., et al., 1997. Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron 19, 127-138.
    • (1997) Neuron , vol.19 , pp. 127-138
    • Bossé, R.1    Fumagalli, F.2    Jaber, M.3
  • 9
    • 0028940880 scopus 로고
    • Antipeptide antibodies confirm the topology of the human norepinephrine transporter
    • Brüss, M., Hammermann, R., Brimijoin, S., Bönisch, H., 1995. Antipeptide antibodies confirm the topology of the human norepinephrine transporter. J. Biol. Chem. 270, 9197-9201.
    • (1995) J. Biol. Chem. , vol.270 , pp. 9197-9201
    • Brüss, M.1    Hammermann, R.2    Brimijoin, S.3    Bönisch, H.4
  • 10
    • 0028577297 scopus 로고
    • Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium
    • Buck, K., Amara, S., 1994. Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium. Proc. Natl. Acad. Sci. U.S.A. 91, 12584-12588.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 12584-12588
    • Buck, K.1    Amara, S.2
  • 11
    • 0029560345 scopus 로고
    • Structural domains of catecholamine transporter chimeras involved in selective inhibition by antidepressants and psychomotor stimulants
    • Buck, K.J., Amara, S.G., 1995. Structural domains of catecholamine transporter chimeras involved in selective inhibition by antidepressants and psychomotor stimulants. Mol. Pharmacol. 48, 1030-1037.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 1030-1037
    • Buck, K.J.1    Amara, S.G.2
  • 12
    • 0030898821 scopus 로고    scopus 로고
    • + permeation and pH regulation at a mammalian serotonin transporter
    • + Permeation and pH regulation at a mammalian serotonin transporter. J. Neurosci. 17, 2257-2266.
    • (1997) J. Neurosci. , vol.17 , pp. 2257-2266
    • Cao, Y.1    Mager, S.2    Lester, H.A.3
  • 13
    • 0031033676 scopus 로고    scopus 로고
    • External cysteine residues in the serotonin transporter
    • Chen, J.-G., Liu-Chen, S., Rudnick, G., 1997. External cysteine residues in the serotonin transporter. Biochemistry 36, 1479-1486.
    • (1997) Biochemistry , vol.36 , pp. 1479-1486
    • Chen, J.-G.1    Liu-Chen, S.2    Rudnick, G.3
  • 14
    • 0030940847 scopus 로고    scopus 로고
    • Analysis of the transmembrane topology and membrane assembly of the GAT1 γ-aminobutyric acid transporter
    • Clark, J.A., 1997. Analysis of the transmembrane topology and membrane assembly of the GAT1 γ-aminobutyric acid transporter. J. Biol. Chem. 272, 14695-14704.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14695-14704
    • Clark, J.A.1
  • 15
    • 0029023535 scopus 로고
    • The role of dopamine in drug abuse viewed from the perspective of its role in motivation
    • Di Chiara, G., 1995. The role of dopamine in drug abuse viewed from the perspective of its role in motivation. Drug Alcohol Depend. 38, 95-137.
    • (1995) Drug Alcohol Depend. , vol.38 , pp. 95-137
    • Di Chiara, G.1
  • 16
    • 0026939128 scopus 로고
    • The transport of neurotransmitters into synaptic vesicles
    • Edwards, R.H., 1992. The transport of neurotransmitters into synaptic vesicles. Curr. Opin. Neurobiol. 2, 586-594.
    • (1992) Curr. Opin. Neurobiol. , vol.2 , pp. 586-594
    • Edwards, R.H.1
  • 17
    • 0027424072 scopus 로고
    • Functional identification and molecular cloning of a human brain vesicle monoamine transporter
    • Erickson, J., Eiden, L., 1993. Functional identification and molecular cloning of a human brain vesicle monoamine transporter. J. Neurochem. 61, 2314-2317.
    • (1993) J. Neurochem. , vol.61 , pp. 2314-2317
    • Erickson, J.1    Eiden, L.2
  • 18
    • 0026458380 scopus 로고
    • Expression cloning of a reserpine-sensitive vesicular monoamine transporter
    • Erickson, J.D., Eiden, L.E., Hoffman, B.J., 1992. Expression cloning of a reserpine-sensitive vesicular monoamine transporter. Proc. Natl. Acad. Sci. U.S.A. 89, 10993-10997.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 10993-10997
    • Erickson, J.D.1    Eiden, L.E.2    Hoffman, B.J.3
  • 19
    • 0029076899 scopus 로고
    • An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
    • Fairman, W.A., Vandenberg, R.J., Arriza, J.L., Kavanaugh, M.P., Amara, S.G., 1995. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375, 599-603.
    • (1995) Nature , vol.375 , pp. 599-603
    • Fairman, W.A.1    Vandenberg, R.J.2    Arriza, J.L.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 20
    • 0030957898 scopus 로고    scopus 로고
    • Individual residues contribute to multiple differences in ligand recognition between vesicular monoamine transporters 1 and 2
    • Finn, J.P., III, Edwards, R.H., 1997. Individual residues contribute to multiple differences in ligand recognition between vesicular monoamine transporters 1 and 2. J. Biol. Chem. 272, 16301-16307.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16301-16307
    • Finn J.P. III1    Edwards, R.H.2
  • 21
    • 0032512754 scopus 로고    scopus 로고
    • Multiple residues contribute independently to differences in ligand recognition between vesicular monoamine transporters 1 and 2
    • Finn, J.P., III, Edwards, R.H., 1998. Multiple residues contribute independently to differences in ligand recognition between vesicular monoamine transporters 1 and 2. J. Biol. Chem. 273, 3943-3947.
    • (1998) J. Biol. Chem. , vol.273 , pp. 3943-3947
    • Finn J.P. III1    Edwards, R.H.2
  • 22
    • 0018393727 scopus 로고
    • Chemical release of dopamine from striatal homogenates: Evidence for an exchange diffusion model
    • Fischer, J.F., Cho, A.K., 1979. Chemical release of dopamine from striatal homogenates: evidence for an exchange diffusion model. J. Pharmacol. Exp. Ther. 208, 203-209.
    • (1979) J. Pharmacol. Exp. Ther. , vol.208 , pp. 203-209
    • Fischer, J.F.1    Cho, A.K.2
  • 23
    • 0031458637 scopus 로고    scopus 로고
    • Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action
    • Fon, E.A., Pothos, E.N., Sun, B.-C., Killeen, N., Sulzer, D., Edwards, R.H., 1997. Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron 19, 1271-1283.
    • (1997) Neuron , vol.19 , pp. 1271-1283
    • Fon, E.A.1    Pothos, E.N.2    Sun, B.-C.3    Killeen, N.4    Sulzer, D.5    Edwards, R.H.6
  • 24
    • 0029379853 scopus 로고
    • Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants
    • Galli, A., DeFelice, L.J., Duke, B.-J., Moore, K.R., Blakely, R.D., 1995. Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants. J. Exp. Biol. 198, 2197-2212.
    • (1995) J. Exp. Biol. , vol.198 , pp. 2197-2212
    • Galli, A.1    DeFelice, L.J.2    Duke, B.-J.3    Moore, K.R.4    Blakely, R.D.5
  • 25
    • 0030982172 scopus 로고    scopus 로고
    • Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel
    • Galli, A., Petersen, C.I., deBlaquiere, M., Blakely, R.D., DeFelice, L.J., 1997. Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel. J. Neurosci. 15, 3401-3411.
    • (1997) J. Neurosci. , vol.15 , pp. 3401-3411
    • Galli, A.1    Petersen, C.I.2    DeBlaquiere, M.3    Blakely, R.D.4    DeFelice, L.J.5
  • 26
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros, B., Jaber, M., Jones, S.R., Wightman, R.M., Caron, M.G., 1996. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379, 606-612.
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 27
    • 0026335164 scopus 로고
    • Cloning and functional characterization of a cocaine-sensitive dopamine transporter
    • Giros, B., Mestikawy, S.E., Bertrand, L., Caron, M.G., 1991. Cloning and functional characterization of a cocaine-sensitive dopamine transporter. FEBS Lett. 295, 149-154.
    • (1991) FEBS Lett. , vol.295 , pp. 149-154
    • Giros, B.1    Mestikawy, S.E.2    Bertrand, L.3    Caron, M.G.4
  • 28
    • 0028341658 scopus 로고
    • Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters
    • Giros, B., Wang, Y.-M., Suter, S., McLeskey, S.B., Pifl, C., Caron, M.G., 1994. Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters. J. Biol. Chem. 269, 15985-15988.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15985-15988
    • Giros, B.1    Wang, Y.-M.2    Suter, S.3    McLeskey, S.B.4    Pifl, C.5    Caron, M.G.6
  • 29
    • 0025048435 scopus 로고
    • Cloning and expression of a rat brain GABA transporter
    • Guastella, J., Nelson, N., Nelson, H., et al., 1990. Cloning and expression of a rat brain GABA transporter. Science 249, 1303-1306.
    • (1990) Science , vol.249 , pp. 1303-1306
    • Guastella, J.1    Nelson, N.2    Nelson, H.3
  • 30
    • 0028819908 scopus 로고
    • GABA transport and calcium dynamics in horizontal cells from the skate retina
    • Haugh-Scheidt, L., Malchow, R.P., Ripps, H., 1995. GABA transport and calcium dynamics in horizontal cells from the skate retina. J. Physiol. 488, 565-576.
    • (1995) J. Physiol. , vol.488 , pp. 565-576
    • Haugh-Scheidt, L.1    Malchow, R.P.2    Ripps, H.3
  • 31
    • 0030781707 scopus 로고    scopus 로고
    • Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra
    • Hersch, S.M., Yi, H., Heilman, C.J., Edwards, R.H., Levey, A.I., 1997. Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra. J. Comp. Neurol. 388, 211-227.
    • (1997) J. Comp. Neurol. , vol.388 , pp. 211-227
    • Hersch, S.M.1    Yi, H.2    Heilman, C.J.3    Edwards, R.H.4    Levey, A.I.5
  • 32
    • 0026350637 scopus 로고
    • Cloning of a serotonin transporter affected by antidepressants
    • Hoffman, B.J., Mezey, E., Brownstein, M.J., 1991. Cloning of a serotonin transporter affected by antidepressants. Science 254, 579-580.
    • (1991) Science , vol.254 , pp. 579-580
    • Hoffman, B.J.1    Mezey, E.2    Brownstein, M.J.3
  • 33
    • 0032521354 scopus 로고    scopus 로고
    • Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter
    • Jones, S.R., Gainetdinov, R.R., Wightman, R.M., Caron, M.G., 1998. Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. J. Neurosci. 18, 1979-1986.
    • (1998) J. Neurosci. , vol.18 , pp. 1979-1986
    • Jones, S.R.1    Gainetdinov, R.R.2    Wightman, R.M.3    Caron, M.G.4
  • 34
    • 0026330894 scopus 로고
    • Cloning and expression of a cocaine-sensitive rat dopamine transporter
    • Kilty, J.E., Lorang, D., Amara, S.G., 1991. Cloning and expression of a cocaine-sensitive rat dopamine transporter. Science 254, 578-579.
    • (1991) Science , vol.254 , pp. 578-579
    • Kilty, J.E.1    Lorang, D.2    Amara, S.G.3
  • 35
    • 0026722234 scopus 로고
    • Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding
    • Kitayama, S., Shimada, S., Xu, H., Markham, L., Donovan, D.M., Uhl, G.R., 1992. Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding. Proc. Natl. Acad. Sci. U.S.A. 89, 7782-7785.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 7782-7785
    • Kitayama, S.1    Shimada, S.2    Xu, H.3    Markham, L.4    Donovan, D.M.5    Uhl, G.R.6
  • 37
    • 0028062672 scopus 로고
    • Structure-activity relationship studies of N-sulfonyl analogs of cocaine: Role of ionic interaction in cocaine binding
    • Kozikowski, A.P., Saiah, M.K.E., Bergmann, J.S., Johnson, K.M., 1994. Structure-activity relationship studies of N-sulfonyl analogs of cocaine: role of ionic interaction in cocaine binding. J. Med. Chem. 37, 3440-3442.
    • (1994) J. Med. Chem. , vol.37 , pp. 3440-3442
    • Kozikowski, A.P.1    Saiah, M.K.E.2    Bergmann, J.S.3    Johnson, K.M.4
  • 39
    • 0029730790 scopus 로고    scopus 로고
    • Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation
    • Lin, F., Lester, H.A., Mager, S., 1996. Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation. Biophys. J. 71, 3126-3135.
    • (1996) Biophys. J. , vol.71 , pp. 3126-3135
    • Lin, F.1    Lester, H.A.2    Mager, S.3
  • 40
    • 0027391644 scopus 로고
    • Molecular characterization of four pharmacologically distinct γ-amminobutyric acid transporters in mouse brain
    • Liu, Q.-R., Lopez-Corcuera, B., Mandiyan, S., Nelson, H., Nelson, N., 1993. Molecular characterization of four pharmacologically distinct γ-amminobutyric acid transporters in mouse brain. J. Biol. Chem. 268, 2106-2112.
    • (1993) J. Biol. Chem. , vol.268 , pp. 2106-2112
    • Liu, Q.-R.1    Lopez-Corcuera, B.2    Mandiyan, S.3    Nelson, H.4    Nelson, N.5
  • 41
    • 0026713852 scopus 로고
    • + toxicity encodes a vesicular amine transporter
    • + toxicity encodes a vesicular amine transporter. Cell 70, 539-551.
    • (1992) Cell , vol.70 , pp. 539-551
    • Liu, Y.1    Peter, D.2    Roghani, A.3
  • 42
    • 0026756443 scopus 로고
    • Gene transfer of a reserpine-sensitive mechanism of resistance to N-methyl-4-phenylpyridinium
    • Liu, Y., Roghani, A., Edwards, R.H., 1992b. Gene transfer of a reserpine-sensitive mechanism of resistance to N-methyl-4-phenylpyridinium. Proc. Natl. Acad. Sci. U.S.A. 89, 9074-9078.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 9074-9078
    • Liu, Y.1    Roghani, A.2    Edwards, R.H.3
  • 43
    • 0031044233 scopus 로고    scopus 로고
    • The role of vesicular transport proteins in synaptic transmission and neural degeneration
    • Liu, Y., Edwards, R.H., 1997. The role of vesicular transport proteins in synaptic transmission and neural degeneration. Annu. Rev. Neurosci. 20, 125-156.
    • (1997) Annu. Rev. Neurosci. , vol.20 , pp. 125-156
    • Liu, Y.1    Edwards, R.H.2
  • 46
    • 0028268596 scopus 로고
    • Conducting states of a mammalian serotonin transporter
    • Mager, S., Min, C., Henry, D., et al., 1994. Conducting states of a mammalian serotonin transporter. Neuron 12, 845-859.
    • (1994) Neuron , vol.12 , pp. 845-859
    • Mager, S.1    Min, C.2    Henry, D.3
  • 47
    • 0027537292 scopus 로고
    • Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes
    • Mager, S., Naeve, J., Quick, M., Labarca, C., Davidson, N., Lester, H.A., 1993. Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes. Neuron 10, 177-188.
    • (1993) Neuron , vol.10 , pp. 177-188
    • Mager, S.1    Naeve, J.2    Quick, M.3    Labarca, C.4    Davidson, N.5    Lester, H.A.6
  • 48
    • 0030734546 scopus 로고    scopus 로고
    • Identification and characterization of the vesicular GABA transporter
    • McIntire, S.L., Reimer, R.J., Schuske, K., Edwards, R.H., Jorgensen, E.M., 1997. Identification and characterization of the vesicular GABA transporter. Nature 389, 870-876.
    • (1997) Nature , vol.389 , pp. 870-876
    • McIntire, S.L.1    Reimer, R.J.2    Schuske, K.3    Edwards, R.H.4    Jorgensen, E.M.5
  • 49
    • 0029788648 scopus 로고    scopus 로고
    • Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition
    • Melikian, H.E., Ramamoorthy, S., Tate, C.G., Blakely, R.D., 1996. Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition. Mol. Pharmacol. 50, 266-276.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 266-276
    • Melikian, H.E.1    Ramamoorthy, S.2    Tate, C.G.3    Blakely, R.D.4
  • 50
    • 0030837830 scopus 로고    scopus 로고
    • 2-Carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: Potent non-nitrogen inhibitors of monoamine transporters
    • Meltzer, P.C., Liang, A.Y., Blundell, P., et al., 1997. 2-Carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: potent non-nitrogen inhibitors of monoamine transporters. J. Med. Chem. 40, 2661-2673.
    • (1997) J. Med. Chem. , vol.40 , pp. 2661-2673
    • Meltzer, P.C.1    Liang, A.Y.2    Blundell, P.3
  • 51
    • 0031054527 scopus 로고    scopus 로고
    • Charged residues in transmembrane domains II and XI of a vesicular monoamine transporter form a charge pair that promotes high affinity substrate recognition
    • Merickel, A., Kaback, H.R., Edwards, R.H., 1997. Charged residues in transmembrane domains II and XI of a vesicular monoamine transporter form a charge pair that promotes high affinity substrate recognition. J. Biol. Chem. 272, 5403-5408.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5403-5408
    • Merickel, A.1    Kaback, H.R.2    Edwards, R.H.3
  • 52
    • 0030038568 scopus 로고    scopus 로고
    • N-linked oligosaccharides are required for cell surface expression of the norepinephrine transporter but do not influence substrate or inhibitor recognition
    • Nguyen, T.T., Amara, S.G., 1996. N-linked oligosaccharides are required for cell surface expression of the norepinephrine transporter but do not influence substrate or inhibitor recognition. J. Neurochem. 67, 645-655.
    • (1996) J. Neurochem. , vol.67 , pp. 645-655
    • Nguyen, T.T.1    Amara, S.G.2
  • 53
    • 0026433037 scopus 로고
    • Expression of cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter
    • Pacholczyk, T., Blakely, R.D., Amara, S.G., 1991. Expression of cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter. Nature 350, 350-353.
    • (1991) Nature , vol.350 , pp. 350-353
    • Pacholczyk, T.1    Blakely, R.D.2    Amara, S.G.3
  • 54
    • 0028263975 scopus 로고
    • The chromaffin granule and synaptic vesicle amine transporters differ in substrate recognition and sensitivity to inhibitors
    • Peter, D., Jimenez, J., Liu, Y., Kim, J., Edwards, R.H., 1994. The chromaffin granule and synaptic vesicle amine transporters differ in substrate recognition and sensitivity to inhibitors. J. Biol. Chem. 269, 7231-7237.
    • (1994) J. Biol. Chem. , vol.269 , pp. 7231-7237
    • Peter, D.1    Jimenez, J.2    Liu, Y.3    Kim, J.4    Edwards, R.H.5
  • 55
    • 0030038198 scopus 로고    scopus 로고
    • Chimeric vesicular monoamine transporters identify structural domains that influence substrate affinity and sensitivity to tetrabenazine
    • Peter, D., Vu, T., Edwards, R.H., 1996. Chimeric vesicular monoamine transporters identify structural domains that influence substrate affinity and sensitivity to tetrabenazine. J. Biol. Chem. 271, 2979-2986.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2979-2986
    • Peter, D.1    Vu, T.2    Edwards, R.H.3
  • 56
    • 0031014266 scopus 로고    scopus 로고
    • Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression
    • Qian, Y., Galli, A., Ramamoorthy, S., Risso, S., DeFelice, L.J., Blakely, R.D., 1997. Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression. J. Neurosci. 17, 45-57.
    • (1997) J. Neurosci. , vol.17 , pp. 45-57
    • Qian, Y.1    Galli, A.2    Ramamoorthy, S.3    Risso, S.4    DeFelice, L.J.5    Blakely, R.D.6
  • 57
    • 0023265754 scopus 로고
    • Cocaine receptors on dopamine transporters are related to self-administration of cocaine
    • Ritz, M.C., Lamb, R.J., Goldberg, S.R., Kuhar, M.J., 1987. Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237, 1219-1223.
    • (1987) Science , vol.237 , pp. 1219-1223
    • Ritz, M.C.1    Lamb, R.J.2    Goldberg, S.R.3    Kuhar, M.J.4
  • 58
    • 0028143612 scopus 로고
    • Molecular cloning of a putative vesicular transporter for acetylcholine
    • Roghani, A., Feldman, J., Kohan, S.A., et al., 1994. Molecular cloning of a putative vesicular transporter for acetylcholine. Proc. Natl. Acad. Sci. U.S.A. 91, 10620-10624.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 10620-10624
    • Roghani, A.1    Feldman, J.2    Kohan, S.A.3
  • 59
    • 0029348098 scopus 로고
    • A review of the effects of dopaminergic agents on humans, animals, and drug-seeking behavior, and its implications for medication development. Focus on GBR 12909
    • Rothman, R.B., Glowa, J.R., 1995. A review of the effects of dopaminergic agents on humans, animals, and drug-seeking behavior, and its implications for medication development. Focus on GBR 12909. Mol. Neurobiol. 11, 1-19.
    • (1995) Mol. Neurobiol. , vol.11 , pp. 1-19
    • Rothman, R.B.1    Glowa, J.R.2
  • 60
    • 0027364736 scopus 로고
    • From synapse to vesicle: The reuptake and storage of biogenic amine neurotransmitters
    • Rudnick, G., Clark, J., 1993. From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters. Biochim. Biophys. Acta 1144, 249-263.
    • (1993) Biochim. Biophys. Acta , vol.1144 , pp. 249-263
    • Rudnick, G.1    Clark, J.2
  • 61
    • 0028339348 scopus 로고
    • A molecular glimpse of vesicular monoamine transporters
    • Schuldiner, S., 1994. A molecular glimpse of vesicular monoamine transporters. J. Neurochem. 62, 2067-2078.
    • (1994) J. Neurochem. , vol.62 , pp. 2067-2078
    • Schuldiner, S.1
  • 62
    • 0027731280 scopus 로고
    • Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters
    • Schuldiner, S., Steiner-Mordoch, S., Yelin, R., Wall, S.C., Rudnick, G., 1993. Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters. Mol. Pharmacol. 44, 1227-1231.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 1227-1231
    • Schuldiner, S.1    Steiner-Mordoch, S.2    Yelin, R.3    Wall, S.C.4    Rudnick, G.5
  • 63
    • 0026315352 scopus 로고
    • Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA
    • Shimada, S., Kitayama, S., Lin, C.-L., et al., 1991. Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA. Science 254, 576-578.
    • (1991) Science , vol.254 , pp. 576-578
    • Shimada, S.1    Kitayama, S.2    Lin, C.-L.3
  • 65
    • 0031036030 scopus 로고    scopus 로고
    • Multiple ionic conductances of human dopamine transporter: The actions of dopamine and psychostimulants
    • Sonders, M.S., Zhu, S.-J., Zahniser, N.R., Kavanaugh, M.P., Amara, S.G., 1997. Multiple ionic conductances of human dopamine transporter: the actions of dopamine and psychostimulants. J. Neurosci. 17, 960-974.
    • (1997) J. Neurosci. , vol.17 , pp. 960-974
    • Sonders, M.S.1    Zhu, S.-J.2    Zahniser, N.R.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 66
    • 0027395913 scopus 로고
    • Amphetamine and other weak bases act to promote reverse transport of dopamine in ventral midbrain neurons
    • Sulzer, D., Maidment, N.T., Rayport, S., 1993. Amphetamine and other weak bases act to promote reverse transport of dopamine in ventral midbrain neurons. J. Neurochem. 60, 527-535.
    • (1993) J. Neurochem. , vol.60 , pp. 527-535
    • Sulzer, D.1    Maidment, N.T.2    Rayport, S.3
  • 67
    • 0025647857 scopus 로고
    • Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: A mechanism of action
    • Sulzer, D., Rayport, S., 1990. Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action. Neuron 5, 797-808.
    • (1990) Neuron , vol.5 , pp. 797-808
    • Sulzer, D.1    Rayport, S.2
  • 68
    • 0031560438 scopus 로고    scopus 로고
    • The rat serotonin transporter: Identification of cysteine residues important for substrate transport
    • Sur, C., Schloss, P., Betz, H., 1997. The rat serotonin transporter: identification of cysteine residues important for substrate transport. Biochem. Biophys. Res. Commun. 241, 68-72.
    • (1997) Biochem. Biophys. Res. Commun. , vol.241 , pp. 68-72
    • Sur, C.1    Schloss, P.2    Betz, H.3
  • 69
    • 0030931721 scopus 로고    scopus 로고
    • VMAT2 knockout mice: Heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity
    • Takahashi, N., Miner, L.L., Sora, I., et al., 1997. VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity. Proc. Natl. Acad. Sci. U.S.A. 94, 9938-9943.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 9938-9943
    • Takahashi, N.1    Miner, L.L.2    Sora, I.3
  • 71
    • 0028195078 scopus 로고
    • Cloning and expression of the vesamicol binding protein from the marine ray Torpedo. Homology with the putative vesicular acetylcholine transporter UNC-17 from Caenorhabditis elegans
    • Varoqui, H., Diebler, M.F., Meunier, F.M., et al., 1994. Cloning and expression of the vesamicol binding protein from the marine ray Torpedo. Homology with the putative vesicular acetylcholine transporter UNC-17 from Caenorhabditis elegans. FEBS Lett. 342, 97-102.
    • (1994) FEBS Lett. , vol.342 , pp. 97-102
    • Varoqui, H.1    Diebler, M.F.2    Meunier, F.M.3
  • 72
    • 0029816108 scopus 로고    scopus 로고
    • Dopamine transporter ligand binding domains
    • Vaughan, R.A., Kuhar, M.J., 1996. Dopamine transporter ligand binding domains. J. Biol. Chem. 271, 21672-21680.
    • (1996) J. Biol. Chem. , vol.271 , pp. 21672-21680
    • Vaughan, R.A.1    Kuhar, M.J.2
  • 73
    • 0029018838 scopus 로고
    • 3 pituitary cells acting via a high-affinity glutamate transporter
    • 3 pituitary cells acting via a high-affinity glutamate transporter. FASEB J. 9, 815-819.
    • (1995) FASEB J. , vol.9 , pp. 815-819
    • Villalobos, C.1    García-Sancho, J.2
  • 74
    • 0028872648 scopus 로고
    • Dopamine transporter cysteine mutants: Second extracellular loop cysteines are required for transporter expression
    • Wang, J.B., Moriwaki, A., Uhl, G.R., 1995. Dopamine transporter cysteine mutants: second extracellular loop cysteines are required for transporter expression. J. Neurochem. 64, 1416-1419.
    • (1995) J. Neurochem. , vol.64 , pp. 1416-1419
    • Wang, J.B.1    Moriwaki, A.2    Uhl, G.R.3
  • 75
    • 0031458923 scopus 로고    scopus 로고
    • Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine
    • Wang, Y.-M., Gainetdinov, R.R., Bock, C.B., Miller, G.W., Wightman, R.M., Caron, M.G., 1997. Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. Neuron 19, 1285-1296.
    • (1997) Neuron , vol.19 , pp. 1285-1296
    • Wang, Y.-M.1    Gainetdinov, R.R.2    Bock, C.B.3    Miller, G.W.4    Wightman, R.M.5    Caron, M.G.6
  • 76
    • 0029888444 scopus 로고    scopus 로고
    • Neurobiology of addiction
    • Wise, R.A., 1996. Neurobiology of addiction. Curr. Opin. Neurobiol. 6, 243-251.
    • (1996) Curr. Opin. Neurobiol. , vol.6 , pp. 243-251
    • Wise, R.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.