-
1
-
-
53849119555
-
-
Ins and outs of major facilitator superfamily antiporters
-
C. J. Law, P. C. Maloney and D. N. Wang. 2008. Ins and outs of major facilitator superfamily antiporters. Annu Rev Microbiol 62, 289-305.
-
(2008)
Annu Rev Microbiol
, vol.62
, pp. 289-305
-
-
Law, C.J.1
Maloney, P.C.2
Wang, D.N.3
-
2
-
-
0025129405
-
Precursor/product antiport in bacteria
-
B. Poolman. 1990. Precursor/product antiport in bacteria. Mol Microbiol 4, 1629-1636.
-
(1990)
Mol Microbiol
, vol.4
, pp. 1629-1636
-
-
Poolman, B.1
-
3
-
-
44849091207
-
Sodium-coupled neurotransmitter transporters
-
B. I. Kanner and E. Zomot. 2008. Sodium-coupled neurotransmitter transporters. Chem Rev 108, 1654-1668.
-
(2008)
Chem Rev
, vol.108
, pp. 1654-1668
-
-
Kanner, B.I.1
Zomot, E.2
-
4
-
-
34249935610
-
Glutamate and monoamine transporters: New visions of form and function
-
G. E. Torres and S. G. Amara. 2007. Glutamate and monoamine transporters: New visions of form and function. Curr Opin Neurobiol 17, 304-312.
-
(2007)
Curr Opin Neurobiol
, vol.17
, pp. 304-312
-
-
Torres, G.E.1
Amara, S.G.2
-
5
-
-
77249090654
-
Emerging structure-function relationships defining monoamine NSS transporter substrate and ligand affinity
-
C. I. Wang and R. J. Lewis. 2010. Emerging structure-function relationships defining monoamine NSS transporter substrate and ligand affinity. Biochem Pharmacol 79, 1083-1091.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 1083-1091
-
-
Wang, C.I.1
Lewis, R.J.2
-
6
-
-
0024371355
-
Characterization of a Na+/glucose cotransporter cloned from rabbit small intestine
-
T. S. Ikeda, E. S. Hwang, M. J. Coady, B. A. Hirayama, M. A. Hediger and E. M. Wright. 1989. Characterization of a Na+/glucose cotransporter cloned from rabbit small intestine. J Membr Biol 110, 87-95.
-
(1989)
J Membr Biol
, vol.110
, pp. 87-95
-
-
Ikeda, T.S.1
Hwang, E.S.2
Coady, M.J.3
Hirayama, B.A.4
Hediger, M.A.5
Wright, E.M.6
-
8
-
-
1242272754
-
Diversity of the mammalian sodium/proton exchanger SLC9 gene family
-
J. Orlowski and S. Grinstein. 2004. Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Pflugers Arch 447, 549-565.
-
(2004)
Pflugers Arch
, vol.447
, pp. 549-565
-
-
Orlowski, J.1
Grinstein, S.2
-
9
-
-
35748942898
-
Bacterial osmosensing transporters
-
J. M. Wood. 2007. Bacterial osmosensing transporters. Methods Enzymol 428, 77-107.
-
(2007)
Methods Enzymol
, vol.428
, pp. 77-107
-
-
Wood, J.M.1
-
11
-
-
0030812843
-
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1
-
K. Tanaka, K. Watase, T. Manabe, K. Yamada, M. Watanabe, K. Takahashi, H. Iwama, T. Nishikawa, N. Ichihara, T. Kikuchi, S. Okuyama, N. Kawashima, S. Hori, M. Takimoto and K. Wada. 1997. Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science 276, 1699-1702.
-
(1997)
Science
, vol.276
, pp. 1699-1702
-
-
Tanaka, K.1
Watase, K.2
Manabe, T.3
Yamada, K.4
Watanabe, M.5
Takahashi, K.6
Iwama, H.7
Nishikawa, T.8
Ichihara, N.9
Kikuchi, T.10
Okuyama, S.11
Kawashima, N.12
Hori, S.13
Takimoto, M.14
Wada, K.15
-
12
-
-
0029860263
-
Flux coupling in a neuronal glutamate transporter
-
N. Zerangue and M. P. Kavanaugh. 1996. Flux coupling in a neuronal glutamate transporter. Nature 383, 634-637.
-
(1996)
Nature
, vol.383
, pp. 634-637
-
-
Zerangue, N.1
Kavanaugh, M.P.2
-
13
-
-
0035993231
-
-
Excitatory amino acid transporters: Keeping up with glutamate
-
S. G. Amara and A. C. Fontana. 2002. Excitatory amino acid transporters: Keeping up with glutamate. Neurochem Int 41, 313-318.
-
(2002)
Fontana
, vol.41
, pp. 313-318
-
-
Amara, S.G.1
-
14
-
-
0035001341
-
Glutamate uptake
-
N. C. Danbolt. 2001. Glutamate uptake. Prog Neurobiol 65, 1-105.
-
(2001)
Prog Neurobiol
, vol.65
, pp. 1-105
-
-
Danbolt, N.C.1
-
15
-
-
0028535115
-
Sodium-coupled neurotransmitter transport: Structure, function and regulation
-
B. I. Kanner. 1994. Sodium-coupled neurotransmitter transport: Structure, function and regulation. J Exp Biol 196, 237-249.
-
(1994)
J Exp Biol
, vol.196
, pp. 237-249
-
-
Kanner, B.I.1
-
16
-
-
33744490360
-
Positioning of proteins in membranes: A computational approach
-
A. L. Lomize, I. D. Pogozheva, M. A. Lomize and H. I. Mosberg. 2006. Positioning of proteins in membranes: A computational approach. Protein Sci 15, 1318-1333.
-
(2006)
Protein Sci
, vol.15
, pp. 1318-1333
-
-
Lomize, A.L.1
Pogozheva, I.D.2
Lomize, M.A.3
Mosberg, H.I.4
-
17
-
-
33751182647
-
The bioinformatic study of transmembrane molecular transport
-
M. H. Saier, Jr. and Q. Ren. 2006. The bioinformatic study of transmembrane molecular transport. J Mol Microbiol Biotechnol 11, 289-290.
-
(2006)
J Mol Microbiol Biotechnol
, vol.11
, pp. 289-290
-
-
Saier, M.H.1
Ren, Q.2
-
18
-
-
33846505059
-
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter
-
Boudker, R. M. Ryan, D. Yernool, K. Shimamoto and E. Gouaux. 2007. Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature 445, 387-393.
-
(2007)
Nature
, vol.445
, pp. 387-393
-
-
Boudker, R.M.R.1
Yernool, D.2
Shimamoto, K.3
Gouaux, E.4
-
19
-
-
72449164409
-
Transport mechanism of a bacterial homologue of glutamate transporters
-
N. Reyes, C. Ginter and O. Boudker. 2009. Transport mechanism of a bacterial homologue of glutamate transporters. Nature 462, 880-885.
-
(2009)
Nature
, vol.462
, pp. 880-885
-
-
Reyes, N.1
Ginter, C.2
Boudker, O.3
-
22
-
-
0036134553
-
Psychostimulants differentially regulate serotonin transporter expression in thalamocortical neurons. J Neurosci 22
-
T. L. Whitworth, L. C. Herndon and M. W. Quick. 2002. Psychostimulants differentially regulate serotonin transporter expression in thalamocortical neurons. J Neurosci 22, RC192.
-
(2002)
RC192
-
-
Whitworth, T.L.1
Herndon, L.C.2
Quick, M.W.3
-
23
-
-
46049086729
-
The binding sites for cocaine and dopamine in the dopamine transporter overlap
-
T. Beuming, J. Kniazeff, M. L. Bergmann, L. Shi, L. Gracia, K. Raniszewska, A. H. Newman, J. A. Javitch, H. Weinstein, U. Gether and C. J. Loland. 2008. The binding sites for cocaine and dopamine in the dopamine transporter overlap. Nat Neurosci 11, 780-789.
-
(2008)
Nat Neurosci
, vol.11
, pp. 780-789
-
-
Beuming, T.1
Kniazeff, J.2
Bergmann, M.L.3
Shi, L.4
Gracia, L.5
Raniszewska, K.6
Newman, A.H.7
Javitch, J.A.8
Weinstein, H.9
Gether, U.10
Loland, C.J.11
-
25
-
-
33846023326
-
Active sugar transport in health and disease
-
E. M. Wright, B. A. Hirayama and D. F. Loo. 2007. Active sugar transport in health and disease. J Intern Med 261, 32-43.
-
(2007)
J Intern Med
, vol.261
, pp. 32-43
-
-
Wright, E.M.1
Hirayama, B.A.2
Loo, D.F.3
-
26
-
-
8344257283
-
A novel SGLT2 mutation in a patient with autosomal recessive renal glucosuria
-
J. Francis, J. Zhang, A. Farhi, H. Carey and D. S. Geller. 2004. A novel SGLT2 mutation in a patient with autosomal recessive renal glucosuria. Nephrol Dial Transplant 19, 2893-2895.
-
(2004)
Nephrol Dial Transplant
, vol.19
, pp. 2893-2895
-
-
Francis, J.1
Zhang, J.2
Farhi, A.3
Carey, H.4
Geller, D.S.5
-
27
-
-
0036368517
-
-
Molecular basis for glucose-galactose malabsorption
-
E. M. Wright, E. Turk and M. G. Martin. 2002. Molecular basis for glucose-galactose malabsorption. Cell Biochem Biophys 36, 115-121.
-
(2002)
Cell Biochem Biophys
, vol.36
, pp. 115-121
-
-
Wright, E.M.1
Turk, E.2
Martin, M.G.3
-
28
-
-
48749106109
-
The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport
-
S. Faham, A. Watanabe, G. M. Besserer, D. Cascio, A. Specht, B. A. Hirayama, E. M. Wright and J. Abramson. 2008. The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport. Science 321, 810-814.
-
(2008)
Science
, vol.321
, pp. 810-814
-
-
Faham, S.1
Watanabe, A.2
Besserer, G.M.3
Cascio, D.4
Specht, A.5
Hirayama, B.A.6
Wright, E.M.7
Abramson, J.8
-
29
-
-
72249106725
-
Ion-releasing state of a secondary membrane transporter
-
J. Li and E. Tajkhorshid. 2009. Ion-releasing state of a secondary membrane transporter. Biophys J 97, L29-L31.
-
(2009)
Biophys J
, vol.97
, pp. L29-L31
-
-
Li, J.1
Tajkhorshid, E.2
-
30
-
-
77952481518
-
The sodium/galactose symporter crystal structure is a dynamic, not so occluded state
-
E. Zomot and I. Bahar. 2010. The sodium/galactose symporter crystal structure is a dynamic, not so occluded state. Mol Biosyst 6, 1040-1046.
-
(2010)
Mol Biosyst
, vol.6
, pp. 1040-1046
-
-
Zomot, E.1
Bahar, I.2
-
31
-
-
0001398337
-
Ageneral theory of membrane transport from studies of bacteria
-
P. Mitchell. 1957. Ageneral theory of membrane transport from studies of bacteria. Nature 180, 134-136.
-
(1957)
Nature
, vol.180
, pp. 134-136
-
-
Mitchell, P.1
-
32
-
-
76049089794
-
Probing of the rates of alternating access in LacY with Trp fluorescence
-
Smirnova, V. Kasho, J. Sugihara and H. R. Kaback. 2009. Probing of the rates of alternating access in LacY with Trp fluorescence. Proc Natl Acad Sci U S A 106, 21561-21566.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 21561-21566
-
-
Smirnova, V.K.1
Sugihara, J.2
Kaback, H.R.3
-
33
-
-
36749074450
-
Sugar binding induces an outward facing conformation of LacY
-
I. Smirnova, V. Kasho, J. Y. Choe, C. Altenbach, W. L. Hubbell and H. R. Kaback. 2007. Sugar binding induces an outward facing conformation of LacY. Proc Natl Acad Sci U S A 104, 16504-16509.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 16504-16509
-
-
Smirnova, I.1
Kasho, V.2
Choe, J.Y.3
Altenbach, C.4
Hubbell, W.L.5
Kaback, H.R.6
-
35
-
-
34547875396
-
Identification of a chloride ion binding site in Na+/Cl -dependent transporters
-
L. R. Forrest, S. Tavoulari, Y. W. Zhang, G. Rudnick and B. Honig. 2007. Identification of a chloride ion binding site in Na+/Cl -dependent transporters. Proc Natl Acad Sci U S A 104, 12761-12766.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12761-12766
-
-
Forrest, L.R.1
Tavoulari, S.2
Zhang, Y.W.3
Rudnick, G.4
Honig, B.5
-
36
-
-
35148815052
-
Mechanism of chloride interaction with neurotransmitter:Sodium symporters
-
E. Zomot, A. Bendahan, M. Quick, Y. Zhao, J. A. Javitch and B. I. Kanner. 2007. Mechanism of chloride interaction with neurotransmitter:sodium symporters. Nature 449, 726-730.
-
(2007)
Nature
, vol.449
, pp. 726-730
-
-
Zomot, E.1
Bendahan, A.2
Quick, M.3
Zhao, Y.4
Javitch, J.A.5
Kanner, B.I.6
-
37
-
-
34548178234
-
Antidepressant binding site in a bacterial homologue of neurotransmitter transporters
-
S. K. Singh, A. Yamashita and E. Gouaux. 2007. Antidepressant binding site in a bacterial homologue of neurotransmitter transporters. Nature 448, 952-956.
-
(2007)
Nature
, vol.448
, pp. 952-956
-
-
Singh, S.K.1
Yamashita, A.2
Gouaux, E.3
-
38
-
-
58149233796
-
A competitive inhibitor traps LeuT in an open-to-out conformation
-
S. K. Singh, C. L. Piscitelli, A. Yamashita and E. Gouaux. 2008. A competitive inhibitor traps LeuT in an open-to-out conformation. Science 322, 1655-1661.
-
(2008)
Science
, vol.322
, pp. 1655-1661
-
-
Singh, S.K.1
Piscitelli, C.L.2
Yamashita, A.3
Gouaux, E.4
-
39
-
-
77950476282
-
Crystal structure of the carnitine transporter and insights into the antiport mechanism
-
L. Tang, L. Bai, W. H. Wang and T. Jiang. 2010. Crystal structure of the carnitine transporter and insights into the antiport mechanism. Nat Struct Mol Biol 17, 492-496.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 492-496
-
-
Tang, L.1
Bai, L.2
Wang, W.H.3
Jiang, T.4
-
40
-
-
55349092991
-
Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter
-
S. Weyand, T. Shimamura, S. Yajima, S. Suzuki, O. Mirza, K. Krusong, E. P. Carpenter, N. G. Rutherford, J. M. Hadden, J. O’Reilly, P. Ma, M. Saidijam, S. G. Patching, R. J. Hope, H. T. Norbertczak, P. C. Roach, S. Iwata, P. J. Henderson and A. D. Cameron. 2008. Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter. Science 322, 709-713.
-
(2008)
Science
, vol.322
, pp. 709-713
-
-
Weyand, S.1
Shimamura, T.2
Yajima, S.3
Suzuki, S.4
Mirza, O.5
Krusong, K.6
Carpenter, E.P.7
Rutherford, N.G.8
Hadden, J.M.9
O’reilly, J.10
Ma, P.11
Saidijam, M.12
Patching, S.G.13
Hope, R.J.14
Norbertczak, H.T.15
Roach, P.C.16
Iwata, S.17
Henderson, P.J.18
Cameron, A.D.19
-
42
-
-
61449361479
-
Review. The molecular logic of sodium-coupled neurotransmitter transporters
-
E. Gouaux. 2009. Review. The molecular logic of sodium-coupled neurotransmitter transporters. Philos Trans R Soc Lond B Biol Sci 364, 149-154.
-
(2009)
Philos Trans R Soc Lond B Biol Sci
, vol.364
, pp. 149-154
-
-
Gouaux, E.1
-
43
-
-
66249098083
-
Unlocking the molecular secrets of sodium-coupled transporters
-
H. Krishnamurthy, C. L. Piscitelli and E. Gouaux. 2009. Unlocking the molecular secrets of sodium-coupled transporters. Nature 459, 347-355.
-
(2009)
Nature
, vol.459
, pp. 347-355
-
-
Krishnamurthy, H.1
Piscitelli, C.L.2
Gouaux, E.3
-
44
-
-
58149291943
-
Molecular mechanism of ion-ion and ionsubstrate coupling in the Na+-dependent leucine transporter LeuT
-
D. A. Caplan, J. O. Subbotina and S. Y. Noskov. 2008. Molecular mechanism of ion-ion and ionsubstrate coupling in the Na+-dependent leucine transporter LeuT. Biophys J 95, 4613-4621.
-
(2008)
Biophys J
, vol.95
, pp. 4613-4621
-
-
Caplan, D.A.1
Subbotina, J.O.2
Noskov, S.Y.3
-
45
-
-
40649098564
-
Control of ion selectivity in LeuT: Two Na+ binding sites with two different mechanisms
-
S. Y. Noskov and B. Roux. 2008. Control of ion selectivity in LeuT: Two Na+ binding sites with two different mechanisms. J Mol Biol 377, 804-818.
-
(2008)
J Mol Biol
, vol.377
, pp. 804-818
-
-
Noskov, S.Y.1
Roux, B.2
-
46
-
-
77952938726
-
Global dynamics of proteins: Bridging between structure and function
-
I. Bahar, T. R. Lezon, L. W. Yang and E. Eyal. 2010. Global dynamics of proteins: Bridging between structure and function. Annu Rev Biophys 39, 23-42.
-
(2010)
Annu Rev Biophys
, vol.39
, pp. 23-42
-
-
Bahar, I.1
Lezon, T.R.2
Yang, L.W.3
Eyal, E.4
-
47
-
-
57649119782
-
Time-resolved mechanism of extracellular gate opening and substrate binding in a glutamate transporter
-
I. H. Shrivastava, J. Jiang, S. G. Amara and I. Bahar. 2008. Time-resolved mechanism of extracellular gate opening and substrate binding in a glutamate transporter. J Biol Chem 283, 28680-28690.
-
(2008)
J Biol Chem
, vol.283
, pp. 28680-28690
-
-
Shrivastava, I.H.1
Jiang, J.2
Amara, S.G.3
Bahar, I.4
-
48
-
-
51649088013
-
Dynamics of the extracellular gate and ion-substrate coupling in the glutamate transporter
-
Z. Huang and E. Tajkhorshid. 2008. Dynamics of the extracellular gate and ion-substrate coupling in the glutamate transporter. Biophys J 95, 2292-2300.
-
(2008)
Biophys J
, vol.95
, pp. 2292-2300
-
-
Huang, Z.1
Tajkhorshid, E.2
-
49
-
-
79951619800
-
The mechanism of substrate release by the aspartate transporter Glt(Ph): Insights from simulations
-
J. Dechancie and I. Bahar. 2011. The mechanism of substrate release by the aspartate transporter Glt(Ph): Insights from simulations. Mol Biosyst 7, 832-842.
-
(2011)
Mol Biosyst
, vol.7
, pp. 832-842
-
-
Dechancie, J.1
Bahar, I.2
-
50
-
-
76749095057
-
Mechanism of substrate recognition and transport by an amino acid antiporter
-
X. Gao, L. Zhou, X. Jiao, F. Lu, C. Yan, X. Zeng, J. Wang and Y. Shi. 2010. Mechanism of substrate recognition and transport by an amino acid antiporter. Nature 463, 828-832.
-
(2010)
Nature
, vol.463
, pp. 828-832
-
-
Gao, X.1
Zhou, L.2
Jiao, X.3
Lu, F.4
Yan, C.5
Zeng, X.6
Wang, J.7
Shi, Y.8
-
51
-
-
40649098564
-
Control of ion selectivity in LeuT: Two Na+ binding sites with two different mechanisms
-
S. Y. Noskov and B. Roux. 2008. Control of ion selectivity in LeuT: Two Na+ binding sites with two different mechanisms. J Mol Biol 377, 804-818.
-
(2008)
J Mol Biol
, vol.377
, pp. 804-818
-
-
Noskov, S.Y.1
Roux, B.2
-
52
-
-
58149291943
-
Molecular mechanism of ion-ion and ionsubstrate coupling in the Na+-dependent leucine transporter
-
D. A. Caplan, J. O. Subbotina and S. Y. Noskov. 2008. Molecular mechanism of ion-ion and ionsubstrate coupling in the Na+-dependent leucine transporter LeuT Biophys J 95, 4613-4621.
-
(2008)
Leut Biophys J
, vol.95
, pp. 4613-4621
-
-
Caplan, D.A.1
Subbotina, J.O.2
Noskov, S.Y.3
-
53
-
-
71349086953
-
Generation of a 3D model for human GABA transporter hGAT-1 using molecular modeling and investigation of the binding of GABA
-
T. Wein and K. T. Wanner. 2009. Generation of a 3D model for human GABA transporter hGAT-1 using molecular modeling and investigation of the binding of GABA. J Mol Model 16, 155-161.
-
(2009)
J Mol Model
, vol.16
, pp. 155-161
-
-
Wein, T.1
Wanner, K.T.2
-
54
-
-
36549031819
-
How dopamine transporter interacts with dopamine: Insights from molecular modeling and simulation
-
X. Huang and C. G. Zhan. 2007. How dopamine transporter interacts with dopamine: Insights from molecular modeling and simulation. Biophys J 93, 3627-3639.
-
(2007)
Biophys J
, vol.93
, pp. 3627-3639
-
-
Huang, X.1
Zhan, C.G.2
-
55
-
-
77949313326
-
Molecular dynamics of leucine and dopamine transporter proteins in a model cell membrane lipid bilayer
-
P. C. Gedeon, M. Indarte, C. K. Surratt and J. D. Madura. 2010. Molecular dynamics of leucine and dopamine transporter proteins in a model cell membrane lipid bilayer. Proteins 78, 797-811.
-
(2010)
Proteins
, vol.78
, pp. 797-811
-
-
Gedeon, P.C.1
Indarte, M.2
Surratt, C.K.3
Madura, J.D.4
-
56
-
-
41449093586
-
Substrate binding and formation of an occluded state in the leucine transporter
-
L. Celik, B. Schiott and E. Tajkhorshid. 2008. Substrate binding and formation of an occluded state in the leucine transporter. Biophys J 94, 1600-1612.
-
(2008)
Biophys J
, vol.94
, pp. 1600-1612
-
-
Celik, L.1
Schiott, B.2
Tajkhorshid, E.3
-
57
-
-
62449268980
-
Molecular simulations elucidate the substrate translocation pathway in a glutamate transporter
-
Y. Gu, I. H. Shrivastava, S. G. Amara and I. Bahar. 2009. Molecular simulations elucidate the substrate translocation pathway in a glutamate transporter. Proc Natl Acad Sci U S A 106, 2589-2594.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2589-2594
-
-
Gu, Y.1
Shrivastava, I.H.2
Amara, S.G.3
Bahar, I.4
-
58
-
-
44949086583
-
The mechanism of a neurotransmitter: Sodium symporter — inward release of Na+ and substrate is triggered by substrate in a second binding site
-
L. Shi, M. Quick, Y. Zhao, H. Weinstein and J. A. Javitch. 2008. The mechanism of a neurotransmitter: sodium symporter — inward release of Na+ and substrate is triggered by substrate in a second binding site. Mol. Cell 30, 667-677.
-
(2008)
Mol. Cell
, vol.30
, pp. 667-677
-
-
Shi, L.1
Quick, M.2
Zhao, Y.3
Weinstein, H.4
Javitch, J.A.5
-
59
-
-
34548684744
-
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake
-
Z. Zhou, J. Zhen, N. K. Karpowich, R. M. Goetz, C. J. Law, M. E. Reith and D. N. Wang. 2007. LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. Science 317, 1390-1393.
-
(2007)
Science
, vol.317
, pp. 1390-1393
-
-
Zhou, Z.1
Zhen, J.2
Karpowich, N.K.3
Goetz, R.M.4
Law, C.J.5
Reith, M.E.6
Wang, D.N.7
-
60
-
-
65249169367
-
Binding of an octyl-glucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation
-
M. Quick, A. M. Winther, L. Shi, P. Nissen, H. Weinstein and J. A. Javitch. 2009. Binding of an octyl-glucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation. Proc Natl Acad Sci U S A 106, 5563-5568.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5563-5568
-
-
Quick, M.1
Winther, A.M.2
Shi, L.3
Nissen, P.4
Weinstein, H.5
Javitch, J.A.6
-
61
-
-
0034682839
-
Molecular characterization of Vibrio parahaemolyticus vSGLT: A model for sodium-coupled sugar cotransporters
-
E. Turk, O. Kim, C. J. le, J. P. Whitelegge, S. Eskandari, J. T. Lam, M. Kreman, G. Zampighi, K. F. Faull and E. M. Wright. 2000. Molecular characterization of Vibrio parahaemolyticus vSGLT: A model for sodium-coupled sugar cotransporters. J Biol Chem 275, 25711-25716.
-
(2000)
J Biol Chem
, vol.275
, pp. 25711-25716
-
-
Turk, E.1
Kim, O.2
Le, C.J.3
Whitelegge, J.P.4
Eskandari, S.5
Lam, J.T.6
Kreman, M.7
Zampighi, G.8
Faull, K.F.9
Wright, E.M.10
-
62
-
-
73949133608
-
Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats
-
T. J. Crisman, S. Qu, B. I. Kanner and L. R. Forrest. 2009. Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats. Proc Natl Acad Sci U S A 106, 20752-20757.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20752-20757
-
-
Crisman, T.J.1
Qu, S.2
Kanner, B.I.3
Forrest, L.R.4
-
63
-
-
48349140230
-
Mechanism for alternating access in neurotransmitter transporters
-
L. R. Forrest, Y. W. Zhang, M. T. Jacobs, J. Gesmonde, L. Xie, B. H. Honig and G. Rudnick. 2008. Mechanism for alternating access in neurotransmitter transporters. Proc Natl Acad Sci U S A 105, 10338-10343.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10338-10343
-
-
Forrest, L.R.1
Zhang, Y.W.2
Jacobs, M.T.3
Gesmonde, J.4
Xie, L.5
Honig, B.H.6
Rudnick, G.7
-
64
-
-
77951585158
-
Molecular basis of alternating access membrane transport by the sodium-hydantoin transporter Mhp1
-
T. Shimamura, S. Weyand, O. Beckstein, N. G. Rutherford, J. M. Hadden, D. Sharples, M. S. Sansom, S. Iwata, P. J. Henderson and A. D. Cameron. 2010. Molecular basis of alternating access membrane transport by the sodium-hydantoin transporter Mhp1. Science 328, 470-473.
-
(2010)
Science
, vol.328
, pp. 470-473
-
-
Shimamura, T.1
Weyand, S.2
Beckstein, O.3
Rutherford, N.G.4
Hadden, J.M.5
Sharples, D.6
Sansom, M.S.7
Iwata, S.8
Henderson, P.J.9
Cameron, A.D.10
-
65
-
-
77949634796
-
Normal mode analysis of biomolecular structures: Functional mechanisms of membrane proteins
-
I. Bahar, T. R. Lezon, A. Bakan and I. H. Shrivastava. 2010. Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins. Chem Rev 110, 1463-1497.
-
(2010)
Chem Rev
, vol.110
, pp. 1463-1497
-
-
Bahar, I.1
Lezon, T.R.2
Bakan, A.3
Shrivastava, I.H.4
-
66
-
-
45849131354
-
Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution
-
O. F. Lange, N. A. Lakomek, C. Fares, G. F. Schroder, K. F. Walter, S. Becker, J. Meiler, H. Grubmuller, C. Griesinger and B. L. de Groot. 2008. Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution. Science 320, 1471-1475.
-
(2008)
Science
, vol.320
, pp. 1471-1475
-
-
Lange, O.F.1
Lakomek, N.A.2
Fares, C.3
Schroder, G.F.4
Walter, K.F.5
Becker, S.6
Meiler, J.7
Grubmuller, H.8
Griesinger, C.9
De Groot, B.L.10
-
67
-
-
70149090164
-
The intrinsic dynamics of enzymes plays a dominant role in determining the structural changes induced upon inhibitor binding
-
A. Bakan and I. Bahar. 2009. The intrinsic dynamics of enzymes plays a dominant role in determining the structural changes induced upon inhibitor binding. Proc Natl Acad Sci U S A 106, 14349-14354.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14349-14354
-
-
Bakan, A.1
Bahar, I.2
-
68
-
-
38949218425
-
Close correspondence between the motions from principal component analysis of multiple HIV-1 protease structures and elastic network modes
-
L. Yang, G. Song, A. Carriquiry and R. L. Jernigan. 2008. Close correspondence between the motions from principal component analysis of multiple HIV-1 protease structures and elastic network modes. Structure 16, 321-330.
-
(2008)
Structure
, vol.16
, pp. 321-330
-
-
Yang, L.1
Song, G.2
Carriquiry, A.3
Jernigan, R.L.4
-
69
-
-
0035132230
-
Anisotropy of fluctuation dynamics of proteins with an elastic network model
-
A. R. Atilgan, S. R. Durell, R. L. Jernigan, M. C. Demirel, O. Keskin and I. Bahar. 2001. Anisotropy of fluctuation dynamics of proteins with an elastic network model. Biophys J 80, 505-515.
-
(2001)
Biophys J
, vol.80
, pp. 505-515
-
-
Atilgan, A.R.1
Durell, S.R.2
Jernigan, R.L.3
Demirel, M.C.4
Keskin, O.5
Bahar, I.6
-
70
-
-
33750407288
-
Anisotropic network model: Systematic evaluation and a new web interface
-
E. Eyal, L. W. Yang and I. Bahar. 2006. Anisotropic network model: Systematic evaluation and a new web interface. Bioinformatics 22, 2619-2627.
-
(2006)
Bioinformatics
, vol.22
, pp. 2619-2627
-
-
Eyal, E.1
Yang, L.W.2
Bahar, I.3
|