A conformational switch in a partially unwound helix selectively determines the pathway for substrate release from the carnitine/γ-butyrobetaine antiporter CaiT

Journal of Biological Chemistry

Volumn 287, Issue 38, 2012, Pages 31823-31832

  Zomot, Elia ^a   Bahar, Ivet ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL MEMBRANES; CARNITINE; CONFORMATIONAL SWITCHES; L-CARNITINE; MOLECULAR DYNAMICS SIMULATIONS; SUBSTRATE-BOUND; TRANSMEMBRANES;

CELLS; CYTOLOGY; MOLECULAR DYNAMICS; SODIUM;

SUBSTRATES;

ANTIPORTER; ARGININE; CAIT PROTEIN; CARNITINE; GAMMA BUTYROLACTONE; SODIUM ION; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CYTOPLASM; DISSOCIATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL;

ANTIPORTERS; ARGININE; BETAINE; BINDING SITES; BIOPHYSICS; CARNITINE; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; CYTOPLASM; ESCHERICHIA COLI PROTEINS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEUS MIRABILIS; SOLVENTS; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS);

EID: 84866376631     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.397364     Document Type: Article

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