Dimerization of the EphA1 receptor tyrosine kinase transmembrane domain: Insights into the mechanism of receptor activation

Biochemistry

Volumn 53, Issue 42, 2014, Pages 6641-6652

  Chavent, Matthieu ^a   Chetwynd, Alan P ^a   Stansfeld, Phillip J ^a   Sansom, Mark S P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; CHEMICAL ACTIVATION; COMPUTER SIMULATION; ENZYME ACTIVITY; FREE ENERGY; LIPID BILAYERS; MOLECULAR DYNAMICS; ROTATION;

ACTIVATION MECHANISMS; ATOMISTIC MOLECULAR DYNAMICS; EXTRACELLULAR DOMAINS; HELIX-HELIX INTERACTIONS; MULTI-SCALE APPROACHES; ONE-DIMENSIONAL POTENTIAL; RECEPTOR TYROSINE KINASE; TRANS-MEMBRANE DOMAINS;

DIMERS;

DIMER; EPHRIN RECEPTOR A1; GLYCINE; LIPID; LIPID BILAYER; PHOSPHOLIPID;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CALCULATION; CONTROLLED STUDY; DIMERIZATION; ELECTRIC POTENTIAL; ENERGY; FORCE; LIPID BILAYER; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POTENTIAL OF MEAN FORCE; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; RECEPTOR BINDING; CHEMISTRY; HUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS;

DIMERIZATION; HUMANS; LIPID BILAYERS; MOLECULAR DYNAMICS SIMULATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHOLIPIDS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPHA1; THERMODYNAMICS;

EID: 84908278525     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500800x     Document Type: Article

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