Insulin receptor activation with transmembrane domain ligands

Journal of Biological Chemistry

Volumn 289, Issue 28, 2014, Pages 19769-19777

  Lee, Jongsoon ^a   Miyazaki, Masaya ^a,b   Romeo, Giulio R ^a   Shoelson, Steven E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CHEMICAL ACTIVATION; INSULIN; LIGANDS; PEPTIDES;

CELLULAR RECEPTORS; EXTENDED SURFACES; GROWTH FACTOR RECEPTORS; INSULIN RESISTANCE; LIGAND BINDING DOMAIN; SPECIFIC INTERACTION; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE DOMAIN;

BIOACTIVITY;

ERYTHROPOIETIN RECEPTOR; GROWTH HORMONE RECEPTOR; INSULIN I 125; INSULIN RECEPTOR; INSULIN RECEPTOR TRANSMEMBRANE DOMAIN PEPTIDE; LIGAND; UNCLASSIFIED DRUG;

3T3 CELL LINE; ANIMAL CELL; ARTICLE; BINDING SITE; CELLULAR DISTRIBUTION; CHO CELL LINE; COMPARATIVE STUDY; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HUMAN; IN VITRO STUDY; INSULIN BINDING; INSULIN RESISTANCE; INTRACELLULAR SIGNALING; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; TRANSMEMBRANE DOMAIN;

INSULIN; INSULIN RECEPTOR; PEPTIDE HORMONE; PEPTIDE LIGAND; RECEPTOR ACTIVATION; RECEPTOR TYROSINE KINASE; TRANSMEMBRANE DOMAIN;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; INSULIN RESISTANCE; MICE; MUTATION; NIH 3T3 CELLS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, INSULIN;

EID: 84904152945     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.578641     Document Type: Article

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