Hydrophobic matching controls the tilt and stability of the dimeric platelet-derived growth factor receptor (PDGFR) α transmembrane segment

Journal of Biological Chemistry

Volumn 287, Issue 31, 2012, Pages 26178-26186

  Muhle Goll, Claudia ^a   Hoffmann, Silke ^a   Afonin, Sergii ^a   Grage, Stephan L ^a   Polyansky, Anton A ^b,c   Windisch, Dirk ^a   Zeitler, Marcel ^a   Bürck, Jochen ^a   Ulrich, Anne S ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF VIENNA   (Austria)

^c SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

BI-LAYER; BILAYER THICKNESS; CELL SURFACE RECEPTORS; CONFORMATIONAL TRANSITIONS; EXPERIMENTAL DATA; GROWTH FACTOR; HELICAL SEGMENTS; HYDROPHOBIC MISMATCH; HYDROPHOBIC SEGMENT; IN-VIVO; LIQUID STATE; MATCHING CONTROL; MICRO-DOMAINS; MODEL MEMBRANES; MOLECULAR DYNAMICS SIMULATIONS; PLATELET-DERIVED GROWTH FACTOR RECEPTORS; PROTEIN AGGREGATION; SOLID STATE NMR; SPHINGOMYELIN; TILT ANGLE; TRANSMEMBRANE SEGMENTS;

AMINO ACIDS; CELL MEMBRANES; HYDROPHOBICITY; LIPID BILAYERS; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOLIPIDS;

DIMERS;

DODECYLPHOSPHORYLCHOLINE; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONTROLLED STUDY; DIMERIZATION; HYDROPHOBICITY; LIPID BILAYER; MICELLE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; STRUCTURE ANALYSIS;

CIRCULAR DICHROISM; CROSS-LINKING REAGENTS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPID BILAYERS; MICELLES; MOLECULAR DYNAMICS SIMULATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SUCCINIMIDES;

EID: 84864387267     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.325555     Document Type: Article

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