Identification of Phe187 as a crucial dimerization determinant facilitates crystallization of a monomeric retroviral integrase core domain

Structure

Volumn 22, Issue 10, 2014, Pages 1512-1519

  Galilee, Meytal ^a   Alian, Akram ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; INTEGRASE; VIRUS ENZYME; PHENYLALANINE; VIRUS PROTEIN;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; CRYSTALLOGRAPHY; DIMERIZATION; DNA BINDING; DNA INTEGRATION; FELINE IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DYNAMICS; NATURAL HOST; NONHUMAN; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN MULTIMERIZATION; VIRUS REPLICATION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; IMMUNODEFICIENCY VIRUS, FELINE; INTEGRASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHENYLALANINE; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; VIRAL PROTEINS;

EID: 84908150994     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2014.08.001     Document Type: Article

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