In vitro functional analyses of the human immunodeficiency virus type 1 (HIV-1) integrase mutants give new insights into the intasome assembly

Virology

Volumn 439, Issue 2, 2013, Pages 97-104

  Cellier, Coralie ^a,b   Moreau, Karen ^a   Gallay, Kathy ^a   Ballandras, Allison ^a   Gouet, Patrice ^a,c   Ronfort, Corinne ^a  

^a UNIVERSITÉ LYON 1   (France)

^b UNIVERSITÉ DE LYON   (France)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Concerted DNA integration; HIV 1; Intasome; Integrase; Mutants

Indexed keywords

ALANINE; GLUTAMIC ACID; INTASOME; INTEGRASE; ISOLEUCINE; TETRAMER; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

ALPHA HELIX; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DNA FLANKING REGION; DNA INTEGRATION; DNA STRAND; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MOLECULAR RECOGNITION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SUBSTITUTION; DNA MUTATIONAL ANALYSIS; DNA, VIRAL; HIV INTEGRASE; HIV-1; HUMANS; MUTATION, MISSENSE; VIRUS INTEGRATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84875811590     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.02.001     Document Type: Article

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