Molecular dynamics simulations of the HIV-1 integrase dimerization interface: Guidelines for the design of a novel class of integrase inhibitors

Journal of Chemical Information and Modeling

Volumn 50, Issue 4, 2010, Pages 604-614

  Sippel, Martin ^a   Sotriffer, Christoph A ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIMERIZATION; DIMERS; LIGANDS;

CLASSICAL APPROACH; HIV-1 INTEGRASE; INHIBITORY PEPTIDES; MOLECULAR DYNAMICS SIMULATIONS; MONOMERIC FORMS; RATIONAL DESIGN; STRUCTURAL DATA; STRUCTURAL FEATURE;

MOLECULAR DYNAMICS;

INTEGRASE; INTEGRASE INHIBITOR;

ARTICLE; CHEMISTRY; DRUG DESIGN; ENZYMOLOGY; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; MOLECULAR DYNAMICS; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; TIME;

DRUG DESIGN; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; MOLECULAR DYNAMICS SIMULATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; TIME FACTORS;

EID: 77951994096     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci900403s     Document Type: Article

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