A crystal structure of the catalytic core domain of an avian sarcoma and leukemia virus integrase suggests an alternate dimeric assembly

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Ballandras, Allison ^a   Moreau, Karen ^b   Robert, Xavier ^a   Confort, Marie Pierre ^b   Merceron, Romain ^a   Haser, Richard ^a   Ronfort, Corinne ^b   Gouet, Patrice ^a  

^a INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

^b UMR 754   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; VIRUS PROTEIN;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; AVIAN SARCOMA VIRUS; BINDING SITE; CATALYTIC CORE DOMAIN; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIMERIZATION; ENZYME ACTIVE SITE; GENE REARRANGEMENT; HUMAN IMMUNODEFICIENCY VIRUS 1; LEUKEMIA VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; ROUS ASSOCIATED VIRUS TYPE 1; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; VIRUS STRAIN; AVIAN LEUKOSIS ONCOVIRUS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; PH; PROTEIN MULTIMERIZATION; RETROVIRUS; SEQUENCE HOMOLOGY; SMALL ANGLE SCATTERING; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

AVES; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RICE STRIPE VIRUS; ROUS-ASSOCIATED VIRUS TYPE 1;

ALPHARETROVIRUS; AMINO ACID SEQUENCE; AVIAN LEUKOSIS VIRUS; AVIAN SARCOMA VIRUSES; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN-ION CONCENTRATION; INTEGRASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SCATTERING, SMALL ANGLE; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL PROTEINS; X-RAY DIFFRACTION;

EID: 79961232399     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023032     Document Type: Article

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