메뉴 건너뛰기




Volumn 25, Issue 6, 2006, Pages 1295-1304

Retroviral DNA integration: Reaction pathway and critical intermediates

Author keywords

Integrase; Integration; Retrovirus; Transposition

Indexed keywords

CELL ENZYME; INTEGRASE; NUCLEOPROTEIN; VIRUS DNA;

EID: 33645285267     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601005     Document Type: Article
Times cited : (213)

References (54)
  • 1
    • 0026458080 scopus 로고
    • DNA-promoted assembly of the active tetramer of the Mu transposase
    • Baker TA, Mizuuchi K (1992) DNA-promoted assembly of the active tetramer of the Mu transposase. Genes Dev 6: 2221-2232
    • (1992) Genes Dev , vol.6 , pp. 2221-2232
    • Baker, T.A.1    Mizuuchi, K.2
  • 3
    • 0030050236 scopus 로고    scopus 로고
    • The three chemical steps of Tn10/IS10 transposition involve repeated utilization of a single active site
    • Bolland S, Kleckner N (1996) The three chemical steps of Tn10/IS10 transposition involve repeated utilization of a single active site. Cell 84: 223-233
    • (1996) Cell , vol.84 , pp. 223-233
    • Bolland, S.1    Kleckner, N.2
  • 4
    • 0024654338 scopus 로고
    • A nucleo-protein complex mediates the integration of retroviral DNA
    • Bowerman B, Brown PO, Bishop JM, Varmus HE (1989) A nucleo-protein complex mediates the integration of retroviral DNA. Genes Dev 3: 469-478
    • (1989) Genes Dev , vol.3 , pp. 469-478
    • Bowerman, B.1    Brown, P.O.2    Bishop, J.M.3    Varmus, H.E.4
  • 5
  • 6
    • 0001363865 scopus 로고    scopus 로고
    • Integration
    • Coffin, JM, Hughes SH, Varmus HE (eds) New York: Cold Spring Harbor Laboratory Press
    • Brown PO (1997) Integration. In Retroviruses, Coffin, JM, Hughes SH, Varmus HE (eds) pp 161-203. New York: Cold Spring Harbor Laboratory Press
    • (1997) Retroviruses , pp. 161-203
    • Brown, P.O.1
  • 8
    • 0026034790 scopus 로고
    • Activities of human immunodeficiency virus (HIV) integration protein in vitro: Specific cleavage and integration of HIV DNA
    • Bushman FD, Craigie R (1991) Activities of human immunodeficiency virus (HIV) integration protein in vitro: Specific cleavage and integration of HIV DNA. Proc Natl Acad Sci USA 88: 1339-1343
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1339-1343
    • Bushman, F.D.1    Craigie, R.2
  • 9
    • 0025133394 scopus 로고
    • Retroviral DNA integration directed by HIV integration protein in vitro
    • Bushman FD, Fujiwara T, Craigie R (1990) Retroviral DNA integration directed by HIV integration protein in vitro. Science 249: 1555-1558
    • (1990) Science , vol.249 , pp. 1555-1558
    • Bushman, F.D.1    Fujiwara, T.2    Craigie, R.3
  • 11
    • 0033380262 scopus 로고    scopus 로고
    • Studies on a 'jumping gene machine': Higher-order nucleoprotein complexes in Mu DNA transposition
    • Chaconas G (1999) Studies on a 'jumping gene machine': higher-order nucleoprotein complexes in Mu DNA transposition. Biochem Cell Biol 77: 487-492
    • (1999) Biochem Cell Biol , vol.77 , pp. 487-492
    • Chaconas, G.1
  • 12
    • 85158020392 scopus 로고    scopus 로고
    • Transposition of phage Mu DNA
    • Craig NL, Craigie R, Gellert M, Lambowitz AM (eds) Washington, DC: ASM Press
    • Chaconas G, Harshey RM (2002) Transposition of phage Mu DNA. In Mobile DNA II, Craig NL, Craigie R, Gellert M, Lambowitz AM (eds) pp 384-402. Washington, DC: ASM Press
    • (2002) Mobile DNA II , pp. 384-402
    • Chaconas, G.1    Harshey, R.M.2
  • 13
    • 0032433829 scopus 로고    scopus 로고
    • The barrier-to-autointegration protein is a host factor for HIV type 1 integration
    • Chen HM, Engelman A (1998) The barrier-to-autointegration protein is a host factor for HIV type 1 integration. Proc Natl Acad Sci USA 95: 15270-15274
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15270-15274
    • Chen, H.M.1    Engelman, A.2
  • 14
    • 0034812967 scopus 로고    scopus 로고
    • Asymmetric processing of human immunodeficiency virus type 1 cDNA in vivo: Implications for functional end coupling during the chemical steps of DNA transposition
    • Chen HM, Engelman A (2001) Asymmetric processing of human immunodeficiency virus type 1 cDNA in vivo: implications for functional end coupling during the chemical steps of DNA transposition. Mol Cell Biol 21: 6758-6767
    • (2001) Mol Cell Biol , vol.21 , pp. 6758-6767
    • Chen, H.M.1    Engelman, A.2
  • 16
  • 17
    • 85158002042 scopus 로고    scopus 로고
    • Retroviral DNA integration
    • Craig NL, Craigie R, Gellert M, Lambowitz AM (eds) Washington, DC: ASM Press
    • Craigie R (2002) Retroviral DNA integration. In Mobile DNA II, Craig NL, Craigie R, Gellert M, Lambowitz AM (eds) pp 613-630. Washington, DC: ASM Press
    • (2002) Mobile DNA II , pp. 613-630
    • Craigie, R.1
  • 18
    • 0034616993 scopus 로고    scopus 로고
    • Three-dimensional structure of the Tn5 synaptic complex transposition intermediate
    • Davies DR, Goryshin IY, Reznikoff WS, Rayment I (2000) Three-dimensional structure of the Tn5 synaptic complex transposition intermediate. Science 289: 77-85
    • (2000) Science , vol.289 , pp. 77-85
    • Davies, D.R.1    Goryshin, I.Y.2    Reznikoff, W.S.3    Rayment, I.4
  • 19
    • 0028584269 scopus 로고
    • Crystal structure of the catalytic domain of HIV-1 integrase: Similarity to other polynucleotidyl transferases
    • Dyda F, Hickman AB, Jenkins TM, Engelman A, Craigie R, Davies DR (1994) Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science 266: 1981-1986
    • (1994) Science , vol.266 , pp. 1981-1986
    • Dyda, F.1    Hickman, A.B.2    Jenkins, T.M.3    Engelman, A.4    Craigie, R.5    Davies, D.R.6
  • 20
    • 0025337327 scopus 로고
    • Human immunodeficiency virus integration in a cell-free system
    • Ellison V, Abrams H, Roe T, Lifson J, Brown PO (1990) Human immunodeficiency virus integration in a cell-free system. J Virol 64: 2711-2715
    • (1990) J Virol , vol.64 , pp. 2711-2715
    • Ellison, V.1    Abrams, H.2    Roe, T.3    Lifson, J.4    Brown, P.O.5
  • 21
    • 0028239062 scopus 로고
    • A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro
    • Ellison V., Brown PO (1994) A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro. Proc Natl Acad Sci USA 91: 7316-7320
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7316-7320
    • Ellison, V.1    Brown, P.O.2
  • 22
    • 0026330796 scopus 로고
    • HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer
    • Engelman A, Mizuuchi K, Craigie R (1991) HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer. Cell 67: 1211-1221
    • (1991) Cell , vol.67 , pp. 1211-1221
    • Engelman, A.1    Mizuuchi, K.2    Craigie, R.3
  • 24
    • 0031004162 scopus 로고    scopus 로고
    • HIV-1 cDNA integration: Requirement of HMG I(Y) protein for function of preintegration complexes in vitro
    • Farnet CM, Bushman FD (1997) HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro. Cell 88: 483-492
    • (1997) Cell , vol.88 , pp. 483-492
    • Farnet, C.M.1    Bushman, F.D.2
  • 25
    • 0025313138 scopus 로고
    • Integration of human immunodeficiency virus type 1 DNA in vitro
    • Farnet CM, Haseltine WA (1990) Integration of human immunodeficiency virus type 1 DNA in vitro. Proc Natl Acad Sci USA 87: 4164-4168
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4164-4168
    • Farnet, C.M.1    Haseltine, W.A.2
  • 27
    • 0028286320 scopus 로고
    • Folding of the multidomain human immunodeficiency virus type-I integrase
    • Grandgenett DP, Goodarzi G (1994) Folding of the multidomain human immunodeficiency virus type-I integrase. Protein Sci 3: 888-897
    • (1994) Protein Sci , vol.3 , pp. 888-897
    • Grandgenett, D.P.1    Goodarzi, G.2
  • 28
    • 0033052713 scopus 로고    scopus 로고
    • HMG protein family members stimulate human immunodeficiency virus type 1 and avian sarcoma virus concerted DNA integration in vitro
    • Hindmarsh P, Ridky T, Reeves R, Andrake M, Skalka AM, Leis J (1999) HMG protein family members stimulate human immunodeficiency virus type 1 and avian sarcoma virus concerted DNA integration in vitro. J Virol 73: 2994-3003
    • (1999) J Virol , vol.73 , pp. 2994-3003
    • Hindmarsh, P.1    Ridky, T.2    Reeves, R.3    Andrake, M.4    Skalka, A.M.5    Leis, J.6
  • 29
    • 0025850374 scopus 로고
    • Structural aspects of a higher-order nucleoprotein complex - Induction of an altered DNA-structure at the Mu-host junction of the Mu-Type-1 transpososome
    • Lavoie BD, Chan BS, Allison RG, Chaconas G (1991) Structural aspects of a higher-order nucleoprotein complex - induction of an altered DNA-structure at the Mu-host junction of the Mu-Type-1 transpososome. EMBO J 10: 3051-3059
    • (1991) EMBO J , vol.10 , pp. 3051-3059
    • Lavoie, B.D.1    Chan, B.S.2    Allison, R.G.3    Chaconas, G.4
  • 30
    • 0030030041 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection
    • Leavitt AD, Robles G, Alesandro N, Varmus HE (1996) Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection. J Virol 70: 721-728
    • (1996) J Virol , vol.70 , pp. 721-728
    • Leavitt, A.D.1    Robles, G.2    Alesandro, N.3    Varmus, H.E.4
  • 31
    • 0028077096 scopus 로고
    • Protection of retroviral DNA from auto-integration: Involvement of a cellular factor
    • Lee MS, Craigie R (1994) Protection of retroviral DNA from auto-integration: involvement of a cellular factor. Proc Natl Acad Sci USA 91: 9823-9827
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9823-9827
    • Lee, M.S.1    Craigie, R.2
  • 32
    • 0028863006 scopus 로고
    • Disassembly of the Mu transposase tetramer by the ClpX chaperone
    • Levchenko I, Luo L, Baker TA (1995) Disassembly of the Mu transposase tetramer by the ClpX chaperone. Genes Dev 9: 2399-2408
    • (1995) Genes Dev , vol.9 , pp. 2399-2408
    • Levchenko, I.1    Luo, L.2    Baker, T.A.3
  • 33
    • 23844491860 scopus 로고    scopus 로고
    • Processing the viral DNA ends channels the HIV-1 integration reaction to concerted integration
    • Li M, Craigie R (2005) Processing the viral DNA ends channels the HIV-1 integration reaction to concerted integration. J Biol Chem 280: 29334-29339
    • (2005) J Biol Chem , vol.280 , pp. 29334-29339
    • Li, M.1    Craigie, R.2
  • 36
    • 0026637325 scopus 로고
    • Transpositional recombination - Mechanistic insights from studies of Mu and other elements
    • Mizuuchi K (1992) Transpositional recombination - mechanistic insights from studies of Mu and other elements. Annu Rev Biochem 61: 1011-1051
    • (1992) Annu Rev Biochem , vol.61 , pp. 1011-1051
    • Mizuuchi, K.1
  • 37
    • 0030628279 scopus 로고    scopus 로고
    • Polynucleotidyl transfer reactions in site-specific DNA recombination
    • Mizuuchi K (1997) Polynucleotidyl transfer reactions in site-specific DNA recombination. Genes Cells 2: 1-12
    • (1997) Genes Cells , vol.2 , pp. 1-12
    • Mizuuchi, K.1
  • 38
    • 0026708067 scopus 로고
    • Assembly of the active form of the transposase-Mu DNA complex: A critical control point in Mu transposition
    • Mizuuchi M, Baker TA, Mizuuchi K (1992) Assembly of the active form of the transposase-Mu DNA complex: a critical control point in Mu transposition. Cell 70: 303-311
    • (1992) Cell , vol.70 , pp. 303-311
    • Mizuuchi, M.1    Baker, T.A.2    Mizuuchi, K.3
  • 39
    • 0026652466 scopus 로고
    • A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo
    • Murphy JE, Goff SP (1992) A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo. J Virol 66: 5092-5095
    • (1992) J Virol , vol.66 , pp. 5092-5095
    • Murphy, J.E.1    Goff, S.P.2
  • 41
    • 0031032592 scopus 로고    scopus 로고
    • 3′-End processing and kinetics of 5′-end joining during retroviral integration in vivo
    • Roe T, Chow SA, Brown PO (1997) 3′-End processing and kinetics of 5′-end joining during retroviral integration in vivo. J Virol 71: 1334-1340
    • (1997) J Virol , vol.71 , pp. 1334-1340
    • Roe, T.1    Chow, S.A.2    Brown, P.O.3
  • 42
    • 0024340289 scopus 로고
    • Structure of the termini of DNA intermediates in the integration of retroviral DNA: Dependence on in function and terminal DNA sequence
    • Roth MJ, Schwartzberg PL, Goff SP (1989) Structure of the termini of DNA intermediates in the integration of retroviral DNA: dependence on IN function and terminal DNA sequence. Cell 58: 47-54
    • (1989) Cell , vol.58 , pp. 47-54
    • Roth, M.J.1    Schwartzberg, P.L.2    Goff, S.P.3
  • 44
    • 0025366844 scopus 로고
    • Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity
    • Sherman PA, Fyfe JA (1990) Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity. Proc Natl Acad Sci USA 87: 5119-5123
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5119-5123
    • Sherman, P.A.1    Fyfe, J.A.2
  • 45
    • 20744447462 scopus 로고    scopus 로고
    • Recombinant human immunodeficiency virus type 1 integrase exhibits a capacity for full-site integration in vitro that is comparable to that of purified preintegration complexes from virus-infected cells
    • Sinha S, Grandgenett DP (2005) Recombinant human immunodeficiency virus type 1 integrase exhibits a capacity for full-site integration in vitro that is comparable to that of purified preintegration complexes from virus-infected cells. J Virol 79: 8208-8216
    • (2005) J Virol , vol.79 , pp. 8208-8216
    • Sinha, S.1    Grandgenett, D.P.2
  • 46
    • 0036118227 scopus 로고    scopus 로고
    • Efficient concerted integration by recombinant human immunodeficiency virus type 1 integrase without cellular or viral cofactors
    • Sinha S, Pursley MH, Grandgenett DP (2002) Efficient concerted integration by recombinant human immunodeficiency virus type 1 integrase without cellular or viral cofactors. J Virol 76: 3105-3113
    • (2002) J Virol , vol.76 , pp. 3105-3113
    • Sinha, S.1    Pursley, M.H.2    Grandgenett, D.P.3
  • 47
    • 0023663468 scopus 로고
    • Transpososomes-stable protein-DNA complexes involved in the in vitro transposition of bacteriophage Mu DNA
    • Surette MG, Buch SJ, Chaconas G (1987) Transpososomes-stable protein-DNA complexes involved in the in vitro transposition of bacteriophage Mu DNA. Cell 49: 253-262
    • (1987) Cell , vol.49 , pp. 253-262
    • Surette, M.G.1    Buch, S.J.2    Chaconas, G.3
  • 48
    • 0026095906 scopus 로고
    • Human immunodeficiency virus integrase protein requires a subterminal position of its viral DNA. J. Virol. Recognition sequence for efficient cleavage
    • Vink C, van Gent DC, Elsgerma Y, Plasterk RHA (1991) Human immunodeficiency virus integrase protein requires a subterminal position of its viral DNA. J. Virol. recognition sequence for efficient cleavage. J Virol 65: 4636-4644
    • (1991) J Virol , vol.65 , pp. 4636-4644
    • Vink, C.1    Van Gent, D.C.2    Elsgerma, Y.3    Plasterk, R.H.A.4
  • 49
    • 0035088065 scopus 로고    scopus 로고
    • DNase protection analysis of retrovirus integrase at the viral DNA ends for full-site integration in vitro
    • Vora A, Grandgenett DP (2001) DNase protection analysis of retrovirus integrase at the viral DNA ends for full-site integration in vitro. J Virol 75: 3556-3567
    • (2001) J Virol , vol.75 , pp. 3556-3567
    • Vora, A.1    Grandgenett, D.P.2
  • 50
    • 0037126629 scopus 로고    scopus 로고
    • Structure of a two-domain fragment of HIV-1 integrase: Implications for domain organization in the intact protein
    • Wang JY, Ling H, Yang W, Craigie R (2001) Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. EMBO J 20: 7333-7343
    • (2001) EMBO J , vol.20 , pp. 7333-7343
    • Wang, J.Y.1    Ling, H.2    Yang, W.3    Craigie, R.4
  • 51
    • 0031449687 scopus 로고    scopus 로고
    • A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration
    • Wei SQ, Mizuuchi K, Craigie R (1997) A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration. EMBO J 16: 7511-7520
    • (1997) EMBO J , vol.16 , pp. 7511-7520
    • Wei, S.Q.1    Mizuuchi, K.2    Craigie, R.3
  • 52
    • 0032169780 scopus 로고    scopus 로고
    • Footprints on the viral DNA ends in Moloney murine leukemia virus preintegration complexes reflect a specific association with integrase
    • Wei SQ, Mizuuchi K, Craigie R (1998) Footprints on the viral DNA ends in Moloney murine leukemia virus preintegration complexes reflect a specific association with integrase. Proc Natl Acad Sci USA 95: 10535-10540
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 10535-10540
    • Wei, S.Q.1    Mizuuchi, K.2    Craigie, R.3
  • 53
    • 0034681303 scopus 로고    scopus 로고
    • Crystal structure of an active two-domain derivative of rous sarcoma virus integrase
    • Yang ZN, Mueser TC, Bushman FD, Hyde CC (2000) Crystal structure of an active two-domain derivative of rous sarcoma virus integrase. J Mol Biol 296: 535-548
    • (2000) J Mol Biol , vol.296 , pp. 535-548
    • Yang, Z.N.1    Mueser, T.C.2    Bushman, F.D.3    Hyde, C.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.