-
1
-
-
67650333178
-
A comprehensive definition for metabolic syndrome
-
2675814, 19407331
-
Huang PL. A comprehensive definition for metabolic syndrome. Dis Model Mech 2009, 2:231-237. 10.1242/dmm.001180, 2675814, 19407331.
-
(2009)
Dis Model Mech
, vol.2
, pp. 231-237
-
-
Huang, P.L.1
-
2
-
-
67349091737
-
Oxidative stress and metabolic syndrome
-
19281826
-
Roberts CK, Sindhu KK. Oxidative stress and metabolic syndrome. Life Sci 2009, 84:705-712. 10.1016/j.lfs.2009.02.026, 19281826.
-
(2009)
Life Sci
, vol.84
, pp. 705-712
-
-
Roberts, C.K.1
Sindhu, K.K.2
-
3
-
-
72649106550
-
A novel component of the metabolic syndrome: the oxidative stress
-
19747805
-
Hopps E, Noto D, Caimi G, Averna MR. A novel component of the metabolic syndrome: the oxidative stress. Nutr Metab Cardiovasc Dis 2010, 20:72-77. 10.1016/j.numecd.2009.06.002, 19747805.
-
(2010)
Nutr Metab Cardiovasc Dis
, vol.20
, pp. 72-77
-
-
Hopps, E.1
Noto, D.2
Caimi, G.3
Averna, M.R.4
-
4
-
-
77954859197
-
The role of mitochondria in the pathogenesis of type 2 diabetes
-
Patti M-E, Corvera S. The role of mitochondria in the pathogenesis of type 2 diabetes. Endocrine Rev 2010, 31:364-395.
-
(2010)
Endocrine Rev
, vol.31
, pp. 364-395
-
-
Patti, M.-E.1
Corvera, S.2
-
5
-
-
0028587742
-
Tumor necrosis factor alpha: a key component of the obesity-diabetes link
-
Hotamisligil GS, Spiegelman BM. Tumor necrosis factor alpha: a key component of the obesity-diabetes link. Diabetes 1994, 43:1271-1278.
-
(1994)
Diabetes
, vol.43
, pp. 1271-1278
-
-
Hotamisligil, G.S.1
Spiegelman, B.M.2
-
6
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
296995, 14679176
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003, 112:1796-1808. 10.1172/JCI200319246, 296995, 14679176.
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
7
-
-
18244372432
-
Mechanisms of insulin resistance in humans and possible links with inflammation
-
15824195
-
Savage DB, Petersen KF, Shulman GI. Mechanisms of insulin resistance in humans and possible links with inflammation. Hypertension 2005, 45:828-833. 10.1161/01.HYP.0000163475.04421.e4, 15824195.
-
(2005)
Hypertension
, vol.45
, pp. 828-833
-
-
Savage, D.B.1
Petersen, K.F.2
Shulman, G.I.3
-
8
-
-
34147125312
-
Defective mitochondrial biogenesis
-
17395885
-
Nisoli E, Clementi E, Carruba MO, Moncada S. Defective mitochondrial biogenesis. Circ Res 2007, 100:795-806. 10.1161/01.RES.0000259591.97107.6c, 17395885.
-
(2007)
Circ Res
, vol.100
, pp. 795-806
-
-
Nisoli, E.1
Clementi, E.2
Carruba, M.O.3
Moncada, S.4
-
9
-
-
33749442351
-
TNF-α downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents
-
1564431, 16981010
-
Valerio A, Cardile A, Cozzi V, Bracale R, Tedesco L, Pisconti A, Palomba L, Cantoni O, Clementi E, Moncada S, Carruba MO, Nisoli E. TNF-α downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents. J Clin Invest 2006, 116:2791-2798. 10.1172/JCI28570., 1564431, 16981010.
-
(2006)
J Clin Invest
, vol.116
, pp. 2791-2798
-
-
Valerio, A.1
Cardile, A.2
Cozzi, V.3
Bracale, R.4
Tedesco, L.5
Pisconti, A.6
Palomba, L.7
Cantoni, O.8
Clementi, E.9
Moncada, S.10
Carruba, M.O.11
Nisoli, E.12
-
11
-
-
77954560505
-
Clinical aspects of coenzyme Q-10; in relationship with its bioenergetic and antioxidant properties
-
Netherlands: Springer, Gvozdjakova A
-
Littarru GP, Tiano L. Clinical aspects of coenzyme Q-10; in relationship with its bioenergetic and antioxidant properties. Mitochondrial Medicine 2008, 303-321. Netherlands: Springer, Gvozdjakova A.
-
(2008)
Mitochondrial Medicine
, pp. 303-321
-
-
Littarru, G.P.1
Tiano, L.2
-
12
-
-
77949562391
-
Coenzyme Q10 contents in foods and fortification strategies
-
20301015
-
Pravst I, Žmitek K, Žmitek J. Coenzyme Q10 contents in foods and fortification strategies. Crit Rev Food Sci Nutr 2010, 50:269-280. 10.1080/10408390902773037, 20301015.
-
(2010)
Crit Rev Food Sci Nutr
, vol.50
, pp. 269-280
-
-
Pravst, I.1
Žmitek, K.2
Žmitek, J.3
-
13
-
-
0030867199
-
Coenzyme Q10 in the diet-daily intake and relative bioavailability
-
Weber C, Bysted A, Hølmer G. Coenzyme Q10 in the diet-daily intake and relative bioavailability. Mol Aspects Med 1997, 18(Supplement 1):251-254.
-
(1997)
Mol Aspects Med
, vol.18
, pp. 251-254
-
-
Weber, C.1
Bysted, A.2
Hølmer, G.3
-
14
-
-
0025195880
-
Co-enzyme Q10: a new drug for cardiovascular disease
-
2202752
-
Greenberg S, Frishman WH. Co-enzyme Q10: a new drug for cardiovascular disease. J Clin Pharmacol 1990, 30:596-608. 10.1002/j.1552-4604.1990.tb01862.x, 2202752.
-
(1990)
J Clin Pharmacol
, vol.30
, pp. 596-608
-
-
Greenberg, S.1
Frishman, W.H.2
-
15
-
-
33645099245
-
Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics
-
16551570
-
Bhagavan HN, Chopra RK. Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res 2006, 40:445-453. 10.1080/10715760600617843, 16551570.
-
(2006)
Free Radic Res
, vol.40
, pp. 445-453
-
-
Bhagavan, H.N.1
Chopra, R.K.2
-
16
-
-
0026636509
-
Distribution and redox state of ubiquinones in rat and human tissues
-
1586151
-
Aberg F, Appelkvist EL, Dallner G, Ernster L. Distribution and redox state of ubiquinones in rat and human tissues. Arch Biochem Biophys 1992, 295:230-234. 10.1016/0003-9861(92)90511-T, 1586151.
-
(1992)
Arch Biochem Biophys
, vol.295
, pp. 230-234
-
-
Aberg, F.1
Appelkvist, E.L.2
Dallner, G.3
Ernster, L.4
-
17
-
-
0025176546
-
Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy
-
2305693
-
Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990, 65:521-523. 10.1016/0002-9149(90)90824-K, 2305693.
-
(1990)
Am J Cardiol
, vol.65
, pp. 521-523
-
-
Langsjoen, P.H.1
Langsjoen, P.H.2
Folkers, K.3
-
18
-
-
0032817975
-
52-Week oral gavage chronic toxicity study with ubiquinone in rats with a 4-week recovery
-
10552718
-
Williams KD, Maneke JD, AbdelHameed M, Hall RL, Palmer TE, Kitano M, Hidaka T. 52-Week oral gavage chronic toxicity study with ubiquinone in rats with a 4-week recovery. J Agric Food Chem 1999, 47:3756-3763. 10.1021/jf981194t, 10552718.
-
(1999)
J Agric Food Chem
, vol.47
, pp. 3756-3763
-
-
Williams, K.D.1
Maneke, J.D.2
AbdelHameed, M.3
Hall, R.L.4
Palmer, T.E.5
Kitano, M.6
Hidaka, T.7
-
19
-
-
0032470151
-
Coenzyme Q10 in cardiovascular disease with emphasis on heart failure and myocardial ischaemia
-
Langsjoen PH, Langsjoen AM. Coenzyme Q10 in cardiovascular disease with emphasis on heart failure and myocardial ischaemia. Asia Pacific Heart J 1998, 7:160-168.
-
(1998)
Asia Pacific Heart J
, vol.7
, pp. 160-168
-
-
Langsjoen, P.H.1
Langsjoen, A.M.2
-
20
-
-
0033796008
-
Regulation of ubiquinone metabolism
-
11035257
-
Dallner G, Sindelar PJ. Regulation of ubiquinone metabolism. Free Radic Biol Med 2000, 29:285-294. 10.1016/S0891-5849(00)00307-5, 11035257.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 285-294
-
-
Dallner, G.1
Sindelar, P.J.2
-
21
-
-
24944584210
-
Mitochondrial dysfunction induces triglyceride accumulation in 3 T3-L1 cells: role of fatty acid beta-oxidation and glucose
-
15741651
-
Vankoningsloo S, Piens M, Lecocq C, Gilson A, De Pauw A, Renard P, Demazy C, Houbion A, Raes M, Arnould T. Mitochondrial dysfunction induces triglyceride accumulation in 3 T3-L1 cells: role of fatty acid beta-oxidation and glucose. J Lipid Res 2005, 46:1133-1149. 10.1194/jlr.M400464-JLR200, 15741651.
-
(2005)
J Lipid Res
, vol.46
, pp. 1133-1149
-
-
Vankoningsloo, S.1
Piens, M.2
Lecocq, C.3
Gilson, A.4
De Pauw, A.5
Renard, P.6
Demazy, C.7
Houbion, A.8
Raes, M.9
Arnould, T.10
-
22
-
-
33644821858
-
Mitochondria are impaired in the adipocytes of type 2 diabetic mice
-
16501941
-
Choo HJ, Kim JH, Kwon OB, Lee C, Mun J, Han S, Yoon YS, Yoon G, Choi KM, Ko YG. Mitochondria are impaired in the adipocytes of type 2 diabetic mice. Diabetologia 2006, 49:784-791. 10.1007/s00125-006-0170-2, 16501941.
-
(2006)
Diabetologia
, vol.49
, pp. 784-791
-
-
Choo, H.J.1
Kim, J.H.2
Kwon, O.B.3
Lee, C.4
Mun, J.5
Han, S.6
Yoon, Y.S.7
Yoon, G.8
Choi, K.M.9
Ko, Y.G.10
-
23
-
-
44649151707
-
The PPAR trio: regulators of myocardial energy metabolism in health and disease
-
18462747
-
Madrazo JA, Kelly DP. The PPAR trio: regulators of myocardial energy metabolism in health and disease. J Mol Cell Cardiol 2008, 44:968-975. 10.1016/j.yjmcc.2008.03.021, 18462747.
-
(2008)
J Mol Cell Cardiol
, vol.44
, pp. 968-975
-
-
Madrazo, J.A.1
Kelly, D.P.2
-
24
-
-
15044339157
-
Role of the PPAR family of nuclear receptors in the regulation of metabolic and cardiovascular homeostasis: new approaches to therapy
-
15780828
-
Chinetti-Gbaguidi G, Fruchart J-C, Staels B. Role of the PPAR family of nuclear receptors in the regulation of metabolic and cardiovascular homeostasis: new approaches to therapy. Curr Opin Pharmacol 2005, 5:177-183. 10.1016/j.coph.2004.11.004, 15780828.
-
(2005)
Curr Opin Pharmacol
, vol.5
, pp. 177-183
-
-
Chinetti-Gbaguidi, G.1
Fruchart, J.-C.2
Staels, B.3
-
25
-
-
77449139468
-
PGC-1α activation as a therapeutic approach in mitochondrial disease
-
19859975
-
Wenz T. PGC-1α activation as a therapeutic approach in mitochondrial disease. Iubmb Life 2009, 61:1051-1062. 10.1002/iub.261, 19859975.
-
(2009)
Iubmb Life
, vol.61
, pp. 1051-1062
-
-
Wenz, T.1
-
26
-
-
49649128985
-
Mitochondrial biogenesis and healthy aging
-
2562606, 18662766
-
López-Lluch G, Irusta PM, Navas P, de Cabo R. Mitochondrial biogenesis and healthy aging. Exp Gerontol 2008, 43:813-819. 10.1016/j.exger.2008.06.014, 2562606, 18662766.
-
(2008)
Exp Gerontol
, vol.43
, pp. 813-819
-
-
López-Lluch, G.1
Irusta, P.M.2
Navas, P.3
de Cabo, R.4
-
27
-
-
0037322888
-
Exercise induces transient transcriptional activation of the PGC-1α gene in human skeletal muscle
-
2342594, 12563009
-
Pilegaard H, Saltin B, Neufer PD. Exercise induces transient transcriptional activation of the PGC-1α gene in human skeletal muscle. J Physiol 2003, 546:851-858. 10.1113/jphysiol.2002.034850, 2342594, 12563009.
-
(2003)
J Physiol
, vol.546
, pp. 851-858
-
-
Pilegaard, H.1
Saltin, B.2
Neufer, P.D.3
-
28
-
-
77954909425
-
PGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity
-
2928513, 20371735
-
Lira VA, Benton CR, Yan Z, Bonen A. PGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity. Am J Physiol Endocrinol Metab 2010, 299:E145-E161. 2928513, 20371735.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
, pp. E145-E161
-
-
Lira, V.A.1
Benton, C.R.2
Yan, Z.3
Bonen, A.4
-
29
-
-
31344433403
-
Peroxisome proliferator-activated receptor gamma coactivator 1 in caloric restriction and other models of longevity
-
16424281
-
Corton JC, Brown-Borg HM. Peroxisome proliferator-activated receptor gamma coactivator 1 in caloric restriction and other models of longevity. J Gerontol A Biol Sci Med Sci 2005, 60:1494-1509. 10.1093/gerona/60.12.1494, 16424281.
-
(2005)
J Gerontol A Biol Sci Med Sci
, vol.60
, pp. 1494-1509
-
-
Corton, J.C.1
Brown-Borg, H.M.2
-
30
-
-
42049114658
-
Activation of peroxisome proliferator-activated receptor pathway stimulates the mitochondrial respiratory chain and can correct deficiencies in patients' cells lacking its components
-
18211970
-
Bastin J, Aubey F, Rötig A, Munnich A, Djouadi F. Activation of peroxisome proliferator-activated receptor pathway stimulates the mitochondrial respiratory chain and can correct deficiencies in patients' cells lacking its components. J Clin Endocrinol Metab 2008, 93:1433-1441. 10.1210/jc.2007-1701, 18211970.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 1433-1441
-
-
Bastin, J.1
Aubey, F.2
Rötig, A.3
Munnich, A.4
Djouadi, F.5
-
31
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
-
17112576
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α. Cell 2006, 127:1109-1122. 10.1016/j.cell.2006.11.013, 17112576.
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
32
-
-
84865625922
-
Coenzyme Q10 increases the fatty acid oxidation through AMPK-mediated PPARα induction in 3 T3-L1 preadipocytes
-
22885103
-
Lee SK, Lee JO, Kim JH, Kim N, You GY, Moon JW, Sha J, Kim SJ, Lee YW, Kang HJ, Park SH, Kim HS. Coenzyme Q10 increases the fatty acid oxidation through AMPK-mediated PPARα induction in 3 T3-L1 preadipocytes. Cell Signal 2012, 24:2329-2336. 10.1016/j.cellsig.2012.07.022, 22885103.
-
(2012)
Cell Signal
, vol.24
, pp. 2329-2336
-
-
Lee, S.K.1
Lee, J.O.2
Kim, J.H.3
Kim, N.4
You, G.Y.5
Moon, J.W.6
Sha, J.7
Kim, S.J.8
Lee, Y.W.9
Kang, H.J.10
Park, S.H.11
Kim, H.S.12
-
33
-
-
0141610413
-
Muscle coenzyme Q deficiency in familial mitochondrial encephalomyopathy
-
286916, 2928337
-
Ogasahara S, Engel AG, Frens D, Mack D. Muscle coenzyme Q deficiency in familial mitochondrial encephalomyopathy. Proc Natl Acad Sci 1989, 86:2379-2382. 10.1073/pnas.86.7.2379, 286916, 2928337.
-
(1989)
Proc Natl Acad Sci
, vol.86
, pp. 2379-2382
-
-
Ogasahara, S.1
Engel, A.G.2
Frens, D.3
Mack, D.4
-
34
-
-
4143093775
-
Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults
-
15313151
-
Miles MV, Horn PS, Tang PH, Morrison JA, Miles L, DeGrauw T, Pesce AJ. Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults. Clin Chim Acta 2004, 347:139-144. 10.1016/j.cccn.2004.04.003, 15313151.
-
(2004)
Clin Chim Acta
, vol.347
, pp. 139-144
-
-
Miles, M.V.1
Horn, P.S.2
Tang, P.H.3
Morrison, J.A.4
Miles, L.5
DeGrauw, T.6
Pesce, A.J.7
-
35
-
-
4744359658
-
Comparison of coenzyme Q10 plasma levels in obese and normal weight children
-
15469864
-
Menke T, Niklowitz P, de Sousa G, Reinehr T, Andler W. Comparison of coenzyme Q10 plasma levels in obese and normal weight children. Clin Chim Acta 2004, 349:121-127. 10.1016/j.cccn.2004.06.015, 15469864.
-
(2004)
Clin Chim Acta
, vol.349
, pp. 121-127
-
-
Menke, T.1
Niklowitz, P.2
de Sousa, G.3
Reinehr, T.4
Andler, W.5
-
36
-
-
7944229937
-
Coenzyme Q10 and diabetic endotheliopathy: oxidative stress and the 'recoupling hypothesis'
-
15256611
-
Chew GT, Watts GF. Coenzyme Q10 and diabetic endotheliopathy: oxidative stress and the 'recoupling hypothesis'. QJM 2004, 97:537-548. 10.1093/qjmed/hch089, 15256611.
-
(2004)
QJM
, vol.97
, pp. 537-548
-
-
Chew, G.T.1
Watts, G.F.2
-
37
-
-
0030607116
-
Plasma ubiquinol/cholesterol ratios in patients with hyperlipidaemia, those with diabetes mellitus and in patients requiring dialysis
-
8879843
-
McDonnell MG, Archbold GPR. Plasma ubiquinol/cholesterol ratios in patients with hyperlipidaemia, those with diabetes mellitus and in patients requiring dialysis. Clin Chim Acta 1996, 253:117-126. 10.1016/0009-8981(96)06357-7, 8879843.
-
(1996)
Clin Chim Acta
, vol.253
, pp. 117-126
-
-
McDonnell, M.G.1
Archbold, G.P.R.2
-
38
-
-
33751233521
-
Oxidative burden in prediabetic and diabetic individuals: evidence from plasma coenzyme Q10
-
17116186
-
Lim SC, Tan HH, Goh SK, Subramaniam T, Sum CF, Tan IK, Lee BL, Ong CN. Oxidative burden in prediabetic and diabetic individuals: evidence from plasma coenzyme Q10. Diabetic Med 2006, 23:1344-1349. 10.1111/j.1464-5491.2006.01996.x, 17116186.
-
(2006)
Diabetic Med
, vol.23
, pp. 1344-1349
-
-
Lim, S.C.1
Tan, H.H.2
Goh, S.K.3
Subramaniam, T.4
Sum, C.F.5
Tan, I.K.6
Lee, B.L.7
Ong, C.N.8
-
39
-
-
67649534542
-
Malondialdehyde and coenzyme Q10 in platelets and serum in type 2 diabetes mellitus: correlation with glycemic control
-
210, 19530339
-
El-ghoroury EA, Raslan HM, Badawy EA, El-Saaid GS, Agybi MH, Siam I, Salem SI. Malondialdehyde and coenzyme Q10 in platelets and serum in type 2 diabetes mellitus: correlation with glycemic control. Blood Coagul Fibrinolysis 2009, 20:248-251. 210, 10.1097/MBC.0b013e3283254549, 19530339.
-
(2009)
Blood Coagul Fibrinolysis
, vol.20
, pp. 248-251
-
-
El-ghoroury, E.A.1
Raslan, H.M.2
Badawy, E.A.3
El-Saaid, G.S.4
Agybi, M.H.5
Siam, I.6
Salem, S.I.7
-
40
-
-
56649118739
-
Antioxidant level and redox status of coenzyme Q10 in the plasma and blood cells of children with diabetes mellitus type 1
-
18694454
-
Menke T, Niklowitz P, Wiesel T, Andler W. Antioxidant level and redox status of coenzyme Q10 in the plasma and blood cells of children with diabetes mellitus type 1. Pediatr Diabetes 2008, 9:540-545. 10.1111/j.1399-5448.2008.00389.x, 18694454.
-
(2008)
Pediatr Diabetes
, vol.9
, pp. 540-545
-
-
Menke, T.1
Niklowitz, P.2
Wiesel, T.3
Andler, W.4
-
41
-
-
7944221535
-
Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction
-
15541254
-
Silver MA, Langsjoen PH, Szabo S, Patil H, Zelinger A. Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction. Am J Cardiol 2004, 94:1306-1310. 10.1016/j.amjcard.2004.07.121, 15541254.
-
(2004)
Am J Cardiol
, vol.94
, pp. 1306-1310
-
-
Silver, M.A.1
Langsjoen, P.H.2
Szabo, S.3
Patil, H.4
Zelinger, A.5
-
42
-
-
0025242794
-
Lovastatin decreases coenzyme Q levels in humans
-
55074, 2247468
-
Folkers K, Langsjoen P, Willis R, Richardson P, Xia LJ, Ye CQ, Tamagawa H. Lovastatin decreases coenzyme Q levels in humans. Proc Natl Acad Sci 1990, 87:8931-8934. 10.1073/pnas.87.22.8931, 55074, 2247468.
-
(1990)
Proc Natl Acad Sci
, vol.87
, pp. 8931-8934
-
-
Folkers, K.1
Langsjoen, P.2
Willis, R.3
Richardson, P.4
Xia, L.J.5
Ye, C.Q.6
Tamagawa, H.7
-
43
-
-
0028725070
-
Exogenous CoQ10 preserves plasma ubiquinone levels in patients treated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
-
7819598
-
Bargossi AM, Battino M, Gaddi A, Fiorella PL, Grossi G, Barozzi G, Di Giulio R, Descovich G, Sassi S, Genova ML, Lenaz G. Exogenous CoQ10 preserves plasma ubiquinone levels in patients treated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Int J Clin Lab Res 1994, 24:171-176. 10.1007/BF02592449, 7819598.
-
(1994)
Int J Clin Lab Res
, vol.24
, pp. 171-176
-
-
Bargossi, A.M.1
Battino, M.2
Gaddi, A.3
Fiorella, P.L.4
Grossi, G.5
Barozzi, G.6
Di Giulio, R.7
Descovich, G.8
Sassi, S.9
Genova, M.L.10
Lenaz, G.11
-
44
-
-
27644465314
-
Statin-associated myopathy with normal creatine kinase levels. Case report from a Norwegian family
-
16218940
-
Troseid M, Henriksen OA, Lindal S. Statin-associated myopathy with normal creatine kinase levels. Case report from a Norwegian family. APMIS 2005, 113:635-637. 10.1111/j.1600-0463.2005.apm_270.x, 16218940.
-
(2005)
APMIS
, vol.113
, pp. 635-637
-
-
Troseid, M.1
Henriksen, O.A.2
Lindal, S.3
-
45
-
-
0036787034
-
Statin-associated myopathy with normal creatine kinase levels
-
12353945
-
Phillips PS, Haas RH, Bannykh S, Hathaway S, Gray NL, Kimura BJ, Vladutiu GD, England JD. Statin-associated myopathy with normal creatine kinase levels. Ann Intern Med 2002, 137:581-585. 10.7326/0003-4819-137-7-200210010-00009, 12353945.
-
(2002)
Ann Intern Med
, vol.137
, pp. 581-585
-
-
Phillips, P.S.1
Haas, R.H.2
Bannykh, S.3
Hathaway, S.4
Gray, N.L.5
Kimura, B.J.6
Vladutiu, G.D.7
England, J.D.8
-
46
-
-
34247639532
-
Effect of coenzyme q10 on myopathic symptoms in patients treated with statins
-
17493470
-
Caso G, Kelly P, McNurlan MA, Lawson WE. Effect of coenzyme q10 on myopathic symptoms in patients treated with statins. Am J Cardiol 2007, 99:1409-1412. 10.1016/j.amjcard.2006.12.063, 17493470.
-
(2007)
Am J Cardiol
, vol.99
, pp. 1409-1412
-
-
Caso, G.1
Kelly, P.2
McNurlan, M.A.3
Lawson, W.E.4
-
47
-
-
0022021457
-
Biochemical rationale and myocardial tissue data on the effective therapy of cardiomyopathy with coenzyme Q10
-
397155, 3856239
-
Folkers K, Vadhanavikit S, Mortensen SA. Biochemical rationale and myocardial tissue data on the effective therapy of cardiomyopathy with coenzyme Q10. Proc Natl Acad Sci 1985, 82:901-904. 10.1073/pnas.82.3.901, 397155, 3856239.
-
(1985)
Proc Natl Acad Sci
, vol.82
, pp. 901-904
-
-
Folkers, K.1
Vadhanavikit, S.2
Mortensen, S.A.3
-
48
-
-
33947602191
-
Genetic determinants of statin intolerance
-
1832194, 17376224
-
Oh J, Ban MR, Miskie BA, Pollex RL, Hegele RA. Genetic determinants of statin intolerance. Lipids Health Dis 2007, 6:7. 10.1186/1476-511X-6-7, 1832194, 17376224.
-
(2007)
Lipids Health Dis
, vol.6
, pp. 7
-
-
Oh, J.1
Ban, M.R.2
Miskie, B.A.3
Pollex, R.L.4
Hegele, R.A.5
-
49
-
-
33746665298
-
Genetic risk factors associated with lipid-lowering drug-induced myopathies
-
16671104
-
Vladutiu GD, Simmons Z, Isackson PJ, Tarnopolsky M, Peltier WL, Barboi AC, Sripathi N, Wortmann RL, Phillips PS. Genetic risk factors associated with lipid-lowering drug-induced myopathies. Muscle Nerve 2006, 34:153-162. 10.1002/mus.20567, 16671104.
-
(2006)
Muscle Nerve
, vol.34
, pp. 153-162
-
-
Vladutiu, G.D.1
Simmons, Z.2
Isackson, P.J.3
Tarnopolsky, M.4
Peltier, W.L.5
Barboi, A.C.6
Sripathi, N.7
Wortmann, R.L.8
Phillips, P.S.9
-
50
-
-
0015436711
-
Vitamin E and free radical peroxidation of lipids
-
4572176
-
Tappel AL. Vitamin E and free radical peroxidation of lipids. Ann N Y Acad Sci 1972, 203:12-28. 10.1111/j.1749-6632.1972.tb27851.x, 4572176.
-
(1972)
Ann N Y Acad Sci
, vol.203
, pp. 12-28
-
-
Tappel, A.L.1
-
51
-
-
0025979077
-
Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol
-
51081, 2000375
-
Stocker R, Bowry VW, Frei B. Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. Proc Natl Acad Sci 1991, 88:1646-1650. 10.1073/pnas.88.5.1646, 51081, 2000375.
-
(1991)
Proc Natl Acad Sci
, vol.88
, pp. 1646-1650
-
-
Stocker, R.1
Bowry, V.W.2
Frei, B.3
-
52
-
-
84908126348
-
-
Rockville, MD: Agency for Healthcare Research and Quality
-
Shekelle P, Hardy ML, Coulter I, Udani J, Spar M, Oda K, Jungvig LK, Tu W, Suttorp MJ, Valentine D, Ramirez L, Shanman R, Newberry SJ. Effect of the supplemental use of antioxidants vitamin C, vitamin E, and coenzyme Q10 for the prevention and treatment of cancer. (Prepared by Southern California Evidence-based Practice Center under Contract No. 290-97-0001.) AHRQ Publication No. 04-E003 2003, Rockville, MD: Agency for Healthcare Research and Quality.
-
(2003)
Effect of the supplemental use of antioxidants vitamin C, vitamin E, and coenzyme Q10 for the prevention and treatment of cancer. (Prepared by Southern California Evidence-based Practice Center under Contract No. 290-97-0001.) AHRQ Publication No. 04-E003
-
-
Shekelle, P.1
Hardy, M.L.2
Coulter, I.3
Udani, J.4
Spar, M.5
Oda, K.6
Jungvig, L.K.7
Tu, W.8
Suttorp, M.J.9
Valentine, D.10
Ramirez, L.11
Shanman, R.12
Newberry, S.J.13
-
53
-
-
34248161002
-
Coenzyme Q, oxidative stress and aging
-
1978491, 17482528
-
Sohal RS, Forster MJ. Coenzyme Q, oxidative stress and aging. Mitochondrion 2007, 7(Suppl):S103-S111. 1978491, 17482528.
-
(2007)
Mitochondrion
, vol.7
, pp. S103-S111
-
-
Sohal, R.S.1
Forster, M.J.2
-
54
-
-
77953034200
-
Chain-breaking antioxidant activity of reduced forms of mitochondria-targeted quinones, a novel type of geroprotectors
-
2830047, 20195487
-
Roginsky VA, Tashlitsky VN, Skulachev VP. Chain-breaking antioxidant activity of reduced forms of mitochondria-targeted quinones, a novel type of geroprotectors. Aging 2009, 1:481-489. 2830047, 20195487.
-
(2009)
Aging
, vol.1
, pp. 481-489
-
-
Roginsky, V.A.1
Tashlitsky, V.N.2
Skulachev, V.P.3
-
55
-
-
56249128541
-
Mechanism of the neuroprotective role of coenzyme Q10 with or without L-dopa in rotenone-induced parkinsonism
-
Abdin AA, Hamouda HE. Mechanism of the neuroprotective role of coenzyme Q10 with or without L-dopa in rotenone-induced parkinsonism. Neuropharmacol 2008, 55:1340-1346.
-
(2008)
Neuropharmacol
, vol.55
, pp. 1340-1346
-
-
Abdin, A.A.1
Hamouda, H.E.2
-
56
-
-
0033216635
-
Coenzyme Q10 enrichment decreases oxidative DNA damage in human lymphocytes
-
10569635
-
Tomasetti M, Littarru GP, Stocker R, Alleva R. Coenzyme Q10 enrichment decreases oxidative DNA damage in human lymphocytes. Free Radic Biol Med 1999, 27:1027-1032. 10.1016/S0891-5849(99)00132-X, 10569635.
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 1027-1032
-
-
Tomasetti, M.1
Littarru, G.P.2
Stocker, R.3
Alleva, R.4
-
57
-
-
0035378494
-
In vivo supplementation with coenzyme Q10 enhances the recovery of human lymphocytes from oxidative DNA damage
-
Tomasetti M, Alleva R, Borghi B, Collins AR. In vivo supplementation with coenzyme Q10 enhances the recovery of human lymphocytes from oxidative DNA damage. FASEB J 2001, 15:1425-1427.
-
(2001)
FASEB J
, vol.15
, pp. 1425-1427
-
-
Tomasetti, M.1
Alleva, R.2
Borghi, B.3
Collins, A.R.4
-
58
-
-
29944435940
-
Effect of coenzyme Q10 on catalase activity and other antioxidant parameters in streptozotocin-induced diabetic rats
-
16388100
-
Modi K, Santani DD, Goyal RK, Bhatt PA. Effect of coenzyme Q10 on catalase activity and other antioxidant parameters in streptozotocin-induced diabetic rats. Biol Trace Elem Res 2006, 109:25-34. 10.1385/BTER:109:1:025, 16388100.
-
(2006)
Biol Trace Elem Res
, vol.109
, pp. 25-34
-
-
Modi, K.1
Santani, D.D.2
Goyal, R.K.3
Bhatt, P.A.4
-
59
-
-
84855221555
-
Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity
-
22222558
-
Fouad AA, Jresat I. Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity. Environ Toxicol Pharmacol 2012, 33:158-167. 10.1016/j.etap.2011.12.011, 22222558.
-
(2012)
Environ Toxicol Pharmacol
, vol.33
, pp. 158-167
-
-
Fouad, A.A.1
Jresat, I.2
-
60
-
-
84856482639
-
Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease
-
21996047
-
Lee B-J, Huang Y-C, Chen S-J, Lin P-T. Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease. Nutrition 2012, 28:250-255. 10.1016/j.nut.2011.06.004, 21996047.
-
(2012)
Nutrition
, vol.28
, pp. 250-255
-
-
Lee, B.-J.1
Huang, Y.-C.2
Chen, S.-J.3
Lin, P.-T.4
-
61
-
-
0030031771
-
Coexpression of heat-shock protein 60 and intercellular-adhesion molecule-1 is related to increased adhesion of monocytes and T cells to aortic endothelium of rats in response to endotoxin
-
Seitz CS, Kleindienst R, Xu Q, Wick G. Coexpression of heat-shock protein 60 and intercellular-adhesion molecule-1 is related to increased adhesion of monocytes and T cells to aortic endothelium of rats in response to endotoxin. Lab Invest 1996, 74:241-252.
-
(1996)
Lab Invest
, vol.74
, pp. 241-252
-
-
Seitz, C.S.1
Kleindienst, R.2
Xu, Q.3
Wick, G.4
-
62
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
296998, 14679177
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003, 112:1821-1830. 10.1172/JCI200319451, 296998, 14679177.
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
63
-
-
18244370762
-
Inflammation, stress, and diabetes
-
1087185, 15864338
-
Wellen KE, Hotamisligil GS. Inflammation, stress, and diabetes. J Clin Invest 2005, 115:1111-1119. 10.1172/JCI200525102, 1087185, 15864338.
-
(2005)
J Clin Invest
, vol.115
, pp. 1111-1119
-
-
Wellen, K.E.1
Hotamisligil, G.S.2
-
64
-
-
33845542363
-
Weight gain induced by high-fat feeding involves increased liver oxidative stress
-
16899792
-
Milagro FI, Campion J, Martinez JA. Weight gain induced by high-fat feeding involves increased liver oxidative stress. Obesity 2006, 14:1118-1123. 10.1038/oby.2006.128, 16899792.
-
(2006)
Obesity
, vol.14
, pp. 1118-1123
-
-
Milagro, F.I.1
Campion, J.2
Martinez, J.A.3
-
65
-
-
34247857663
-
Obesity, inflammation, and insulin resistance
-
Shoelson SE, Herrero L, Naaz A. Obesity, inflammation, and insulin resistance. Gastroenterol 2007, 132:2169-2180.
-
(2007)
Gastroenterol
, vol.132
, pp. 2169-2180
-
-
Shoelson, S.E.1
Herrero, L.2
Naaz, A.3
-
66
-
-
34548400409
-
Inflammation and obesity: stamping out insulin resistance?
-
17646847
-
Abedini A, Shoelson SE. Inflammation and obesity: stamping out insulin resistance?. Immunol Cell Biol 2007, 85:399-400. 10.1038/sj.icb.7100107, 17646847.
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 399-400
-
-
Abedini, A.1
Shoelson, S.E.2
-
67
-
-
20044387026
-
IKK-beta links inflammation to obesity-induced insulin resistance
-
15685170
-
Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M. IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med 2005, 11:191-198. 10.1038/nm1185, 15685170.
-
(2005)
Nat Med
, vol.11
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.W.5
Long, J.M.6
Wynshaw-Boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
-
68
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
-
1440292, 15685173
-
Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 2005, 11:183-190. 10.1038/nm1166, 1440292, 15685173.
-
(2005)
Nat Med
, vol.11
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
69
-
-
70349932622
-
Association between C-reactive protein and adiposity in women
-
19584180
-
Bochud M, Marquant F, Marques-Vidal P-M, Vollenweider P, Beckmann JS, Mooser V, Paccaud F, Rousson V. Association between C-reactive protein and adiposity in women. J Clin Endocrinol Metab 2009, 94:3969-3977. 10.1210/jc.2008-2428, 19584180.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 3969-3977
-
-
Bochud, M.1
Marquant, F.2
Marques-Vidal, P.-M.3
Vollenweider, P.4
Beckmann, J.S.5
Mooser, V.6
Paccaud, F.7
Rousson, V.8
-
70
-
-
69549105884
-
Abdominal adiposity is associated with elevated C-reactive protein independent of BMI in healthy nonobese people
-
2732149, 19587368
-
Lapice E, Maione S, Patti L, Cipriano P, Rivellese AA, Riccardi G, Vaccaro O. Abdominal adiposity is associated with elevated C-reactive protein independent of BMI in healthy nonobese people. Diabetes Care 2009, 32:1734-1736. 10.2337/dc09-0176, 2732149, 19587368.
-
(2009)
Diabetes Care
, vol.32
, pp. 1734-1736
-
-
Lapice, E.1
Maione, S.2
Patti, L.3
Cipriano, P.4
Rivellese, A.A.5
Riccardi, G.6
Vaccaro, O.7
-
71
-
-
70350565467
-
Neutrophil activation in morbid obesity, chronic activation of acute inflammation
-
19390527
-
Nijhuis J, Rensen SS, Slaats Y, van Dielen FM, Buurman WA, Greve JW. Neutrophil activation in morbid obesity, chronic activation of acute inflammation. Obesity 2009, 17:2014-2018. 10.1038/oby.2009.113, 19390527.
-
(2009)
Obesity
, vol.17
, pp. 2014-2018
-
-
Nijhuis, J.1
Rensen, S.S.2
Slaats, Y.3
van Dielen, F.M.4
Buurman, W.A.5
Greve, J.W.6
-
72
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
-
7678183
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993, 259:87-91. 10.1126/science.7678183, 7678183.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
73
-
-
0033073540
-
The role of TNF alpha in adipocyte metabolism
-
10355025
-
Sethi JK, Hotamisligil GS. The role of TNF alpha in adipocyte metabolism. Semin Cell Dev Biol 1999, 10:19-29. 10.1006/scdb.1998.0273, 10355025.
-
(1999)
Semin Cell Dev Biol
, vol.10
, pp. 19-29
-
-
Sethi, J.K.1
Hotamisligil, G.S.2
-
74
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
-
295872, 7738205
-
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995, 95:2409-2415. 10.1172/JCI117936, 295872, 7738205.
-
(1995)
J Clin Invest
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
75
-
-
0028968879
-
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
-
295809, 7738178
-
Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 1995, 95:2111-2119. 10.1172/JCI117899, 295809, 7738178.
-
(1995)
J Clin Invest
, vol.95
, pp. 2111-2119
-
-
Kern, P.A.1
Saghizadeh, M.2
Ong, J.M.3
Bosch, R.J.4
Deem, R.5
Simsolo, R.B.6
-
76
-
-
79953030266
-
The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids
-
21310207
-
El-Moselhy MA, Taye A, Sharkawi SS, El-Sisi SFI, Ahmed AF. The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids. Food Chem Toxicol 2011, 49:1129-1140. 10.1016/j.fct.2011.02.004, 21310207.
-
(2011)
Food Chem Toxicol
, vol.49
, pp. 1129-1140
-
-
El-Moselhy, M.A.1
Taye, A.2
Sharkawi, S.S.3
El-Sisi, S.F.I.4
Ahmed, A.F.5
-
77
-
-
77449146665
-
Experimental Endotoxemia induces adipose inflammation and insulin resistance in humans
-
2797919, 19794059
-
Mehta NN, McGillicuddy FC, Anderson PD, Hinkle CC, Shah R, Pruscino L, Tabita-Martinez J, Sellers KF, Rickels MR, Reilly MP. Experimental Endotoxemia induces adipose inflammation and insulin resistance in humans. Diabetes 2010, 59:172-181. 10.2337/db09-0367, 2797919, 19794059.
-
(2010)
Diabetes
, vol.59
, pp. 172-181
-
-
Mehta, N.N.1
McGillicuddy, F.C.2
Anderson, P.D.3
Hinkle, C.C.4
Shah, R.5
Pruscino, L.6
Tabita-Martinez, J.7
Sellers, K.F.8
Rickels, M.R.9
Reilly, M.P.10
-
78
-
-
84863911000
-
Cholesterol-lowering drugs inhibit lectin-like oxidized low-density lipoprotein-1 receptor function by membrane raft disruption
-
22570368
-
Matarazzo S, Quitadamo MC, Mango R, Ciccone S, Novelli G, Biocca S. Cholesterol-lowering drugs inhibit lectin-like oxidized low-density lipoprotein-1 receptor function by membrane raft disruption. Mol Pharmacol 2012, 82:246-254. 10.1124/mol.112.078915, 22570368.
-
(2012)
Mol Pharmacol
, vol.82
, pp. 246-254
-
-
Matarazzo, S.1
Quitadamo, M.C.2
Mango, R.3
Ciccone, S.4
Novelli, G.5
Biocca, S.6
-
79
-
-
84856297712
-
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease
-
3266276, 22295101
-
Bieghs V, Van Gorp PJ, Wouters K, Hendrikx T, Gijbels MJ, van Bilsen M, Bakker J, Binder CJ, Lutjohann D, Staels B, Hofker MH, Shiri-Sverdlov R. LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease. Plos One 2012, 7:e30668. 10.1371/journal.pone.0030668, 3266276, 22295101.
-
(2012)
Plos One
, vol.7
, pp. e30668
-
-
Bieghs, V.1
Van Gorp, P.J.2
Wouters, K.3
Hendrikx, T.4
Gijbels, M.J.5
van Bilsen, M.6
Bakker, J.7
Binder, C.J.8
Lutjohann, D.9
Staels, B.10
Hofker, M.H.11
Shiri-Sverdlov, R.12
-
80
-
-
84860459972
-
Effects of adiposity on plasma lipid response to reductions in dietary saturated fatty acids and cholesterol
-
3090171, 22332058
-
Flock MR, Green MH, Kris-Etherton PM. Effects of adiposity on plasma lipid response to reductions in dietary saturated fatty acids and cholesterol. Advances in Nutrition 2011, 2:261-274. 10.3945/an.111.000422, 3090171, 22332058.
-
(2011)
Advances in Nutrition
, vol.2
, pp. 261-274
-
-
Flock, M.R.1
Green, M.H.2
Kris-Etherton, P.M.3
-
81
-
-
0030857878
-
Low-density lipoprotein receptor knockout mice exhibit exaggerated microvascular responses to inflammatory stimuli
-
Henninger DD, Gerritsen ME, Granger DN. Low-density lipoprotein receptor knockout mice exhibit exaggerated microvascular responses to inflammatory stimuli. Cir Res 1997, 81:274-281.
-
(1997)
Cir Res
, vol.81
, pp. 274-281
-
-
Henninger, D.D.1
Gerritsen, M.E.2
Granger, D.N.3
-
82
-
-
0041924007
-
Induction of fatal inflammation in LDL receptor and ApoA-I double-knockout mice fed dietary fat and cholesterol
-
1868257, 12937162
-
Zabalawi M, Bhat S, Loughlin T, Thomas MJ, Alexander E, Cline M, Bullock B, Willingham M, Sorci-Thomas MG. Induction of fatal inflammation in LDL receptor and ApoA-I double-knockout mice fed dietary fat and cholesterol. Am J Pathol 2003, 163:1201-1213. 10.1016/S0002-9440(10)63480-3, 1868257, 12937162.
-
(2003)
Am J Pathol
, vol.163
, pp. 1201-1213
-
-
Zabalawi, M.1
Bhat, S.2
Loughlin, T.3
Thomas, M.J.4
Alexander, E.5
Cline, M.6
Bullock, B.7
Willingham, M.8
Sorci-Thomas, M.G.9
-
83
-
-
0033864582
-
Peroxisome proliferator-activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
-
380255, 10953027
-
Li AC, Brown KK, Silvestre MJ, Willson TM, Palinski W, Glass CK. Peroxisome proliferator-activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice. J Clin Invest 2000, 106:523-531. 10.1172/JCI10370, 380255, 10953027.
-
(2000)
J Clin Invest
, vol.106
, pp. 523-531
-
-
Li, A.C.1
Brown, K.K.2
Silvestre, M.J.3
Willson, T.M.4
Palinski, W.5
Glass, C.K.6
-
84
-
-
0031886864
-
The peroxisome proliferator-activated receptor-[gamma] is a negative regulator of macrophage activation
-
9422508
-
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-[gamma] is a negative regulator of macrophage activation. Nature 1998, 391:79-82. 10.1038/34178, 9422508.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
85
-
-
33745309774
-
The role of the peroxisome proliferator-activated receptor-alpha (PPAR-alpha) in the regulation of acute inflammation
-
16501055
-
Cuzzocrea S, Mazzon E, Di Paola R, Peli A, Bonato A, Britti D, Genovese T, Muia C, Crisafulli C, Caputi AP. The role of the peroxisome proliferator-activated receptor-alpha (PPAR-alpha) in the regulation of acute inflammation. J Leukoc Biol 2006, 79:999-1010. 10.1189/jlb.0605341, 16501055.
-
(2006)
J Leukoc Biol
, vol.79
, pp. 999-1010
-
-
Cuzzocrea, S.1
Mazzon, E.2
Di Paola, R.3
Peli, A.4
Bonato, A.5
Britti, D.6
Genovese, T.7
Muia, C.8
Crisafulli, C.9
Caputi, A.P.10
-
86
-
-
60849106971
-
In vitro effects of the reduced form of coenzyme Q10 on secretion levels of TNF-α and chemokines in response to LPS in the human monocytic cell line THP-1
-
Schmelzer C, Lorenz G, Rimbach G, Döring F. In vitro effects of the reduced form of coenzyme Q10 on secretion levels of TNF-α and chemokines in response to LPS in the human monocytic cell line THP-1. J Nutr Biochem 2009, 44:62-66.
-
(2009)
J Nutr Biochem
, vol.44
, pp. 62-66
-
-
Schmelzer, C.1
Lorenz, G.2
Rimbach, G.3
Döring, F.4
-
87
-
-
57349102400
-
Influence of Coenzyme Q10 on release of pro-inflammatory chemokines in the human monocytic cell line THP-1
-
18997284
-
Schmelzer C, Lorenz G, Rimbach G, Döring F. Influence of Coenzyme Q10 on release of pro-inflammatory chemokines in the human monocytic cell line THP-1. BioFactors 2007, 31:211-217. 10.1002/biof.5520310308, 18997284.
-
(2007)
BioFactors
, vol.31
, pp. 211-217
-
-
Schmelzer, C.1
Lorenz, G.2
Rimbach, G.3
Döring, F.4
-
88
-
-
60249097822
-
Coadministration of coenzyme Q prevents rosiglitazone-induced adipogenesis in ob/ob mice
-
Carmona MC, Lefebvre P, Lefebvre B, Galinier A, Benani A, Jeanson Y, Louche K, Flajollet S, Ktorza A, Dacquet C, Penicaud L, Casteilla L. Coadministration of coenzyme Q prevents rosiglitazone-induced adipogenesis in ob/ob mice. Int J Obes 2009, 33:204-211.
-
(2009)
Int J Obes
, vol.33
, pp. 204-211
-
-
Carmona, M.C.1
Lefebvre, P.2
Lefebvre, B.3
Galinier, A.4
Benani, A.5
Jeanson, Y.6
Louche, K.7
Flajollet, S.8
Ktorza, A.9
Dacquet, C.10
Penicaud, L.11
Casteilla, L.12
-
89
-
-
70349767934
-
Coenzyme Q10 supplementation lowers hepatic oxidative stress and inflammation associated with diet-induced obesity in mice
-
19632207
-
Sohet FM, Neyrinck AM, Pachikian BD, de Backer FC, Bindels LB, Niklowitz P, Menke T, Cani PD, Delzenne NM. Coenzyme Q10 supplementation lowers hepatic oxidative stress and inflammation associated with diet-induced obesity in mice. Biochem Pharmacol 2009, 78:1391-1400. 10.1016/j.bcp.2009.07.008, 19632207.
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 1391-1400
-
-
Sohet, F.M.1
Neyrinck, A.M.2
Pachikian, B.D.3
de Backer, F.C.4
Bindels, L.B.5
Niklowitz, P.6
Menke, T.7
Cani, P.D.8
Delzenne, N.M.9
-
90
-
-
84857871990
-
Ubiquinol affects the expression of genes involved in PPARalpha signalling and lipid metabolism without changes in methylation of CpG promoter islands in the liver of mice
-
3303474, 22448092
-
Schmelzer C, Kitano M, Hosoe K, Doring F. Ubiquinol affects the expression of genes involved in PPARalpha signalling and lipid metabolism without changes in methylation of CpG promoter islands in the liver of mice. J Clin Biochem Nutr 2012, 50:119-126. 10.3164/jcbn.11-19, 3303474, 22448092.
-
(2012)
J Clin Biochem Nutr
, vol.50
, pp. 119-126
-
-
Schmelzer, C.1
Kitano, M.2
Hosoe, K.3
Doring, F.4
-
91
-
-
77954171665
-
Supplementation with the reduced form of Coenzyme Q10 decelerates phenotypic characteristics of senescence and induces a peroxisome proliferator-activated receptor-α gene expression signature in SAMP1 mice
-
Schmelzer C, Kubo H, Mori M, Sawashita J, Kitano M, Hosoe K, Boomgaarden I, Döring F, Higuchi K. Supplementation with the reduced form of Coenzyme Q10 decelerates phenotypic characteristics of senescence and induces a peroxisome proliferator-activated receptor-α gene expression signature in SAMP1 mice. Mol Nutr Food Res 2010, 54:805-815.
-
(2010)
Mol Nutr Food Res
, vol.54
, pp. 805-815
-
-
Schmelzer, C.1
Kubo, H.2
Mori, M.3
Sawashita, J.4
Kitano, M.5
Hosoe, K.6
Boomgaarden, I.7
Döring, F.8
Higuchi, K.9
-
92
-
-
46449129625
-
Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome
-
18544898
-
Kunitomo M, Yamaguchi Y, Kagota S, Otsubo K. Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome. J Pharmacol Sci 2008, 107:128-137. 10.1254/jphs.FP0072365, 18544898.
-
(2008)
J Pharmacol Sci
, vol.107
, pp. 128-137
-
-
Kunitomo, M.1
Yamaguchi, Y.2
Kagota, S.3
Otsubo, K.4
-
93
-
-
84857805203
-
Effects of coenzyme Q10 and alpha-lipoic acid supplementation in fructose fed rats
-
full_text, 3303477, 22448096
-
Ozdogan S, Kaman D, Simsek BC. Effects of coenzyme Q10 and alpha-lipoic acid supplementation in fructose fed rats. J Clin Biochem Nutr 2012, 50:145-151. full_text, 3303477, 22448096.
-
(2012)
J Clin Biochem Nutr
, vol.50
, pp. 145-151
-
-
Ozdogan, S.1
Kaman, D.2
Simsek, B.C.3
-
94
-
-
65949119758
-
Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients
-
2671099, 19228872
-
Hamilton SJ, Chew GT, Watts GF. Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. Diabetes Care 2009, 32:810-812. 10.2337/dc08-1736, 2671099, 19228872.
-
(2009)
Diabetes Care
, vol.32
, pp. 810-812
-
-
Hamilton, S.J.1
Chew, G.T.2
Watts, G.F.3
-
95
-
-
84859831151
-
A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways
-
21684136
-
Tsai KL, Huang YH, Kao CL, Yang DM, Lee HC, Chou HY, Chen YC, Chiou GY, Chen LH, Yang YP, Chiu TH, Tsai CS, Ou HC, Chiou SH. A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways. J Nutr Biochem 2012, 23:458-468. 10.1016/j.jnutbio.2011.01.011, 21684136.
-
(2012)
J Nutr Biochem
, vol.23
, pp. 458-468
-
-
Tsai, K.L.1
Huang, Y.H.2
Kao, C.L.3
Yang, D.M.4
Lee, H.C.5
Chou, H.Y.6
Chen, Y.C.7
Chiou, G.Y.8
Chen, L.H.9
Yang, Y.P.10
Chiu, T.H.11
Tsai, C.S.12
Ou, H.C.13
Chiou, S.H.14
-
96
-
-
34548721636
-
Effect of coenzyme Q10 administration on endothelial function and extracellular superoxide dismutase in patients with ischaemic heart disease: a double-blind, randomized controlled study
-
17644511
-
Tiano L, Belardinelli R, Carnevali P, Principi F, Seddaiu G, Littarru GP. Effect of coenzyme Q10 administration on endothelial function and extracellular superoxide dismutase in patients with ischaemic heart disease: a double-blind, randomized controlled study. Eur Heart J 2007, 28:2249-2255. 10.1093/eurheartj/ehm267, 17644511.
-
(2007)
Eur Heart J
, vol.28
, pp. 2249-2255
-
-
Tiano, L.1
Belardinelli, R.2
Carnevali, P.3
Principi, F.4
Seddaiu, G.5
Littarru, G.P.6
-
97
-
-
0016135162
-
Reduction by coenzyme Q10 of hypertension induced by deoxycorticosterone and saline in rats
-
Yamagami T, Iwamoto Y, Folkers K, Blomqvist CG. Reduction by coenzyme Q10 of hypertension induced by deoxycorticosterone and saline in rats. Int J Vitam Nutr Res 1974, 44:487-496.
-
(1974)
Int J Vitam Nutr Res
, vol.44
, pp. 487-496
-
-
Yamagami, T.1
Iwamoto, Y.2
Folkers, K.3
Blomqvist, C.G.4
-
98
-
-
0016137070
-
Deficiency of coenzyme Q10 in hypertensive rats and reduction of deficiency by treatment with coenzyme Q10
-
4836275
-
Iwamoto Y, Yamagami T, Folkers K, Blomqvist CG. Deficiency of coenzyme Q10 in hypertensive rats and reduction of deficiency by treatment with coenzyme Q10. Biochem Biophys Res Commun 1974, 58:743-748. 10.1016/S0006-291X(74)80480-8, 4836275.
-
(1974)
Biochem Biophys Res Commun
, vol.58
, pp. 743-748
-
-
Iwamoto, Y.1
Yamagami, T.2
Folkers, K.3
Blomqvist, C.G.4
-
99
-
-
38049161857
-
Effects of decylubiquinone (coenzyme Q10 analog) supplementation on SHRSP
-
18198397
-
Murad LB, Guimaraes MR, Vianna LM. Effects of decylubiquinone (coenzyme Q10 analog) supplementation on SHRSP. BioFactors 2007, 30:13-18. 10.1002/biof.5520300102, 18198397.
-
(2007)
BioFactors
, vol.30
, pp. 13-18
-
-
Murad, L.B.1
Guimaraes, M.R.2
Vianna, L.M.3
-
100
-
-
33947423399
-
Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials
-
Rosenfeldt FL, Haas SJ, Krum H, Hadj A, Ng K, Leong JY, Watts GF. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum Hypertens 2007, 21:297-306.
-
(2007)
J Hum Hypertens
, vol.21
, pp. 297-306
-
-
Rosenfeldt, F.L.1
Haas, S.J.2
Krum, H.3
Hadj, A.4
Ng, K.5
Leong, J.Y.6
Watts, G.F.7
-
101
-
-
84856035599
-
A randomized, double-blind, placebo-controlled crossover study of coenzyme q10 therapy in hypertensive patients with the metabolic syndrome
-
22113168
-
Young JM, Florkowski CM, Molyneux SL, McEwan RG, Frampton CM, Nicholls MG, Scott RS, George PM. A randomized, double-blind, placebo-controlled crossover study of coenzyme q10 therapy in hypertensive patients with the metabolic syndrome. Am J Hypertens 2012, 25:261-270. 10.1038/ajh.2011.209, 22113168.
-
(2012)
Am J Hypertens
, vol.25
, pp. 261-270
-
-
Young, J.M.1
Florkowski, C.M.2
Molyneux, S.L.3
McEwan, R.G.4
Frampton, C.M.5
Nicholls, M.G.6
Scott, R.S.7
George, P.M.8
-
102
-
-
0028618698
-
Coenzyme Q10 in essential hypertension
-
Digiesi V, Cantini F, Oradei A, Bisi G, Guarino GC, Brocchi A, Bellandi F, Mancini M, Littarru GP. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994, 15(Suppl):s257-s263.
-
(1994)
Mol Aspects Med
, vol.15
, pp. s257-s263
-
-
Digiesi, V.1
Cantini, F.2
Oradei, A.3
Bisi, G.4
Guarino, G.C.5
Brocchi, A.6
Bellandi, F.7
Mancini, M.8
Littarru, G.P.9
-
103
-
-
34248217519
-
Coenzyme Q10 in cardiovascular disease
-
Pepe S, Marasco SF, Haas SJ, Sheeran FL, Krum H, Rosenfeldt FL. Coenzyme Q10 in cardiovascular disease. Mitochondrion 2007, 7(Suppl):S154-S167.
-
(2007)
Mitochondrion
, vol.7
, pp. S154-S167
-
-
Pepe, S.1
Marasco, S.F.2
Haas, S.J.3
Sheeran, F.L.4
Krum, H.5
Rosenfeldt, F.L.6
-
104
-
-
0031829432
-
Control of arterial tone after long-term coenzyme Q10 supplementation in senescent rats
-
1565529, 9723964
-
Lonnrot K, Porsti I, Alho H, Wu X, Hervonen A, Tolvanen JP. Control of arterial tone after long-term coenzyme Q10 supplementation in senescent rats. Br J Pharmacol 1998, 124:1500-1506. 10.1038/sj.bjp.0701970, 1565529, 9723964.
-
(1998)
Br J Pharmacol
, vol.124
, pp. 1500-1506
-
-
Lonnrot, K.1
Porsti, I.2
Alho, H.3
Wu, X.4
Hervonen, A.5
Tolvanen, J.P.6
-
105
-
-
70449529407
-
Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-like syndrome
-
19638284
-
Kumar A, Kaur H, Devi P, Mohan V. Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-like syndrome. Pharmacol Ther 2009, 124:259-268. 10.1016/j.pharmthera.2009.07.003, 19638284.
-
(2009)
Pharmacol Ther
, vol.124
, pp. 259-268
-
-
Kumar, A.1
Kaur, H.2
Devi, P.3
Mohan, V.4
-
106
-
-
0031881379
-
Heart failure: is there an energy deficit contributing to contractile dysfunction?
-
Vogt AM, Kübler W. Heart failure: is there an energy deficit contributing to contractile dysfunction?. Basic Res Cardiol 1998, 93:1-10.
-
(1998)
Basic Res Cardiol
, vol.93
, pp. 1-10
-
-
Vogt, A.M.1
Kübler, W.2
-
107
-
-
0014720452
-
Evidence for a deficiency of coenzyme Q10 in human heart disease
-
Folkers K, Littarru GP, Ho L, Runge TM, Havanonda S, Cooley D. Evidence for a deficiency of coenzyme Q10 in human heart disease. Int Z Vitaminforsch 1970, 40:380-390.
-
(1970)
Int Z Vitaminforsch
, vol.40
, pp. 380-390
-
-
Folkers, K.1
Littarru, G.P.2
Ho, L.3
Runge, T.M.4
Havanonda, S.5
Cooley, D.6
-
108
-
-
0025086659
-
A six-year clinical study of therapy of cardiomyopathy with coenzyme Q10
-
Langsjoen PH, Folkers K. A six-year clinical study of therapy of cardiomyopathy with coenzyme Q10. Int J Tissue React 1990, 12:169-171.
-
(1990)
Int J Tissue React
, vol.12
, pp. 169-171
-
-
Langsjoen, P.H.1
Folkers, K.2
-
109
-
-
0030770431
-
Treatment of hypertrophic cardiomyopathy with coenzyme Q10
-
Langsjoen PH, Langsjoen A, Willis R, Folkers K. Treatment of hypertrophic cardiomyopathy with coenzyme Q10. Mol Aspects Med 1997, 18(Suppl):S145-S151.
-
(1997)
Mol Aspects Med
, vol.18
, pp. S145-S151
-
-
Langsjoen, P.H.1
Langsjoen, A.2
Willis, R.3
Folkers, K.4
-
110
-
-
0019381272
-
A protective effect of coenzyme Q10 on ischemia and reperfusion of the isolated perfused rat heart
-
Ohhara H, Kanaide H, Yoshimura R, Okada M, Nakamura M. A protective effect of coenzyme Q10 on ischemia and reperfusion of the isolated perfused rat heart. J Mol Cell Cardiol 1981, 13:65-74.
-
(1981)
J Mol Cell Cardiol
, vol.13
, pp. 65-74
-
-
Ohhara, H.1
Kanaide, H.2
Yoshimura, R.3
Okada, M.4
Nakamura, M.5
-
111
-
-
0028455370
-
Coenzyme Q10 enhances cardiac functional and metabolic recovery and reduces Ca2+ overload during postischemic reperfusion
-
Hano O, Thompson-Gorman SL, Zweier JL, Lakatta EG. Coenzyme Q10 enhances cardiac functional and metabolic recovery and reduces Ca2+ overload during postischemic reperfusion. Am J Physiol 1994, 266:H2174-H2181.
-
(1994)
Am J Physiol
, vol.266
, pp. H2174-H2181
-
-
Hano, O.1
Thompson-Gorman, S.L.2
Zweier, J.L.3
Lakatta, E.G.4
-
112
-
-
0033032252
-
Bioenergetic effect of liposomal coenzyme Q10 on myocardial ischemia reperfusion injury
-
10416045
-
Niibori K, Wroblewski KP, Yokoyama H, Crestanello JA, Whitman GJ. Bioenergetic effect of liposomal coenzyme Q10 on myocardial ischemia reperfusion injury. BioFactors 1999, 9:307-313. 10.1002/biof.5520090228, 10416045.
-
(1999)
BioFactors
, vol.9
, pp. 307-313
-
-
Niibori, K.1
Wroblewski, K.P.2
Yokoyama, H.3
Crestanello, J.A.4
Whitman, G.J.5
-
113
-
-
0017625595
-
Reduction by coenzyme Q10 of the acute toxicity of adriamycin in mice
-
Combs AB, Choe JY, Truong DH, Folkers K. Reduction by coenzyme Q10 of the acute toxicity of adriamycin in mice. Res Commun Chem Pathol Pharmacol 1977, 18:565-568.
-
(1977)
Res Commun Chem Pathol Pharmacol
, vol.18
, pp. 565-568
-
-
Combs, A.B.1
Choe, J.Y.2
Truong, D.H.3
Folkers, K.4
-
114
-
-
0021288630
-
Effect of coenzyme Q10 on the survival time and lipid peroxidation of adriamycin (doxorubicin) treated mice
-
Shinozawa S, Etowo K, Araki Y, Oda T. Effect of coenzyme Q10 on the survival time and lipid peroxidation of adriamycin (doxorubicin) treated mice. Acta Med Okayama 1984, 38:57-63.
-
(1984)
Acta Med Okayama
, vol.38
, pp. 57-63
-
-
Shinozawa, S.1
Etowo, K.2
Araki, Y.3
Oda, T.4
-
115
-
-
0033812251
-
Deficit of coenzyme Q in heart and liver mitochondria of rats with streptozotocin-induced diabetes
-
Kucharska J, Braunova Z, Ulicna O, Zlatos L, Gvozdjakova A. Deficit of coenzyme Q in heart and liver mitochondria of rats with streptozotocin-induced diabetes. Physiol Res 2000, 49:411-418.
-
(2000)
Physiol Res
, vol.49
, pp. 411-418
-
-
Kucharska, J.1
Braunova, Z.2
Ulicna, O.3
Zlatos, L.4
Gvozdjakova, A.5
-
116
-
-
0032588765
-
Coenzyme Q10 depletion and mitochondrial energy disturbances in rejection development in patients after heart transplantation
-
10416044
-
Gvozdjakova A, Kucharska J, Mizera S, Braunova Z, Schreinerova Z, Schramekova E, Pechan I, Fabian J. Coenzyme Q10 depletion and mitochondrial energy disturbances in rejection development in patients after heart transplantation. BioFactors 1999, 9:301-306. 10.1002/biof.5520090227, 10416044.
-
(1999)
BioFactors
, vol.9
, pp. 301-306
-
-
Gvozdjakova, A.1
Kucharska, J.2
Mizera, S.3
Braunova, Z.4
Schreinerova, Z.5
Schramekova, E.6
Pechan, I.7
Fabian, J.8
-
117
-
-
0032588774
-
The effect of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus
-
10416046
-
Eriksson JG, Forsen TJ, Mortensen SA, Rohde M. The effect of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus. BioFactors 1999, 9:315-318. 10.1002/biof.5520090229, 10416046.
-
(1999)
BioFactors
, vol.9
, pp. 315-318
-
-
Eriksson, J.G.1
Forsen, T.J.2
Mortensen, S.A.3
Rohde, M.4
-
118
-
-
0032757898
-
Impact of ubiquinone (coenzyme Q10) treatment on glycaemic control, insulin requirement and well-being in patients with Type 1 diabetes mellitus
-
10220205
-
Henriksen JE, Andersen CB, Hother-Nielsen O, Vaag A, Mortensen SA, Beck-Nielsen H. Impact of ubiquinone (coenzyme Q10) treatment on glycaemic control, insulin requirement and well-being in patients with Type 1 diabetes mellitus. Diabet Med 1999, 16:312-318. 10.1046/j.1464-5491.1999.00064.x, 10220205.
-
(1999)
Diabet Med
, vol.16
, pp. 312-318
-
-
Henriksen, J.E.1
Andersen, C.B.2
Hother-Nielsen, O.3
Vaag, A.4
Mortensen, S.A.5
Beck-Nielsen, H.6
-
119
-
-
38349117774
-
Supplementation of coenzyme Q10 and α-tocopherol lowers glycated hemoglobin level and lipid peroxidation in pancreas of diabetic rats
-
19083397
-
Sena CM, Nunes E, Gomes A, Santos MS, Proença T, Martins MI, Seiça RM. Supplementation of coenzyme Q10 and α-tocopherol lowers glycated hemoglobin level and lipid peroxidation in pancreas of diabetic rats. Nutr Res 2008, 28:113-121. 10.1016/j.nutres.2007.12.005, 19083397.
-
(2008)
Nutr Res
, vol.28
, pp. 113-121
-
-
Sena, C.M.1
Nunes, E.2
Gomes, A.3
Santos, M.S.4
Proença, T.5
Martins, M.I.6
Seiça, R.M.7
-
120
-
-
0036851863
-
The liver X receptor gene team: potential new players in atherosclerosis
-
12411951
-
Repa JJ, Mangelsdorf DJ. The liver X receptor gene team: potential new players in atherosclerosis. Nat Med 2002, 8:1243-1248. 10.1038/nm1102-1243, 12411951.
-
(2002)
Nat Med
, vol.8
, pp. 1243-1248
-
-
Repa, J.J.1
Mangelsdorf, D.J.2
-
121
-
-
11144356074
-
Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor γ expression
-
381668, 15060163
-
Seo JB, Moon HM, Kim WS, Lee YS, Jeong HW, Yoo EJ, Ham J, Kang H, Park M-G, Steffensen KR, Stulnig TM, Gustafsson J, Park SD, Kim JB. Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor γ expression. Mol Cell Biol 2004, 24:3430-3444. 10.1128/MCB.24.8.3430-3444.2004, 381668, 15060163.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 3430-3444
-
-
Seo, J.B.1
Moon, H.M.2
Kim, W.S.3
Lee, Y.S.4
Jeong, H.W.5
Yoo, E.J.6
Ham, J.7
Kang, H.8
Park, M.-G.9
Steffensen, K.R.10
Stulnig, T.M.11
Gustafsson, J.12
Park, S.D.13
Kim, J.B.14
-
122
-
-
0037324340
-
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
-
12524534
-
Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med 2003, 9:213-219. 10.1038/nm820, 12524534.
-
(2003)
Nat Med
, vol.9
, pp. 213-219
-
-
Joseph, S.B.1
Castrillo, A.2
Laffitte, B.A.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
123
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
-
9630215
-
Peet DJ, Turley SD, Ma W, Janowski BA, Lobaccaro JM, Hammer RE, Mangelsdorf DJ. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 1998, 93:693-704. 10.1016/S0092-8674(00)81432-4, 9630215.
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.M.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
124
-
-
12444295462
-
Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling
-
12730332
-
Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Yatoh S, Iizuka Y, Tomita S, Ohashi K, Takahashi A, Sone H, Gotoda T, Osuga J-I, Ishibashi S, Yamada N. Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling. Mol Endocrinol 2003, 17:1255-1267. 10.1210/me.2002-0191, 12730332.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1255-1267
-
-
Ide, T.1
Shimano, H.2
Yoshikawa, T.3
Yahagi, N.4
Amemiya-Kudo, M.5
Matsuzaka, T.6
Nakakuki, M.7
Yatoh, S.8
Iizuka, Y.9
Tomita, S.10
Ohashi, K.11
Takahashi, A.12
Sone, H.13
Gotoda, T.14
Osuga, J.-I.15
Ishibashi, S.16
Yamada, N.17
-
125
-
-
79952018447
-
The reduced form of coenzyme Q10 mediates distinct effects on cholesterol metabolism at the transcriptional and metabolite level in SAMP1 mice
-
21086475
-
Schmelzer C, Okun JG, Haas D, Higuchi K, Sawashita J, Mori M, Doring F. The reduced form of coenzyme Q10 mediates distinct effects on cholesterol metabolism at the transcriptional and metabolite level in SAMP1 mice. Iubmb Life 2010, 62:812-818. 10.1002/iub.388, 21086475.
-
(2010)
Iubmb Life
, vol.62
, pp. 812-818
-
-
Schmelzer, C.1
Okun, J.G.2
Haas, D.3
Higuchi, K.4
Sawashita, J.5
Mori, M.6
Doring, F.7
-
126
-
-
84867937358
-
Influence of liver-X-receptor on tissue cholesterol, coenzyme Q and dolichol content
-
Bentinger M, Tekle M, Dallner G, Brismar K, Gustafsson J, Steffensen K, Catrina SB. Influence of liver-X-receptor on tissue cholesterol, coenzyme Q and dolichol content. Molec Membrane Biol 2012, 29:299-308.
-
(2012)
Molec Membrane Biol
, vol.29
, pp. 299-308
-
-
Bentinger, M.1
Tekle, M.2
Dallner, G.3
Brismar, K.4
Gustafsson, J.5
Steffensen, K.6
Catrina, S.B.7
-
127
-
-
33746095409
-
Life-long supplementation with a low dosage of coenzyme Q10 in the rat: effects on antioxidant status and DNA damage
-
16873932
-
Quiles JL, Ochoa JJ, Battino M, Gutierrez-Rios P, Nepomuceno EA, Frias ML, Huertas JR, Mataix J. Life-long supplementation with a low dosage of coenzyme Q10 in the rat: effects on antioxidant status and DNA damage. BioFactors 2005, 25:73-86. 10.1002/biof.5520250109, 16873932.
-
(2005)
BioFactors
, vol.25
, pp. 73-86
-
-
Quiles, J.L.1
Ochoa, J.J.2
Battino, M.3
Gutierrez-Rios, P.4
Nepomuceno, E.A.5
Frias, M.L.6
Huertas, J.R.7
Mataix, J.8
-
128
-
-
0842348226
-
Coenzyme Q supplementation protects from age-related DNA double-strand breaks and increases lifespan in rats fed on a PUFA-rich diet
-
15036411
-
Quiles JL, Ochoa JJ, Huertas JR, Mataix J. Coenzyme Q supplementation protects from age-related DNA double-strand breaks and increases lifespan in rats fed on a PUFA-rich diet. Exp Gerontol 2004, 39:189-194. 10.1016/j.exger.2003.10.002, 15036411.
-
(2004)
Exp Gerontol
, vol.39
, pp. 189-194
-
-
Quiles, J.L.1
Ochoa, J.J.2
Huertas, J.R.3
Mataix, J.4
-
129
-
-
70349761355
-
Induction of non-alcoholic fatty liver disease and insulin resistance by feeding a high-fat diet in rats: does coenzyme Q monomethyl ether have a modulatory effect?
-
19592219
-
Safwat GM, Pisano S, D'Amore E, Borioni G, Napolitano M, Kamal AA, Ballanti P, Botham KM, Bravo E. Induction of non-alcoholic fatty liver disease and insulin resistance by feeding a high-fat diet in rats: does coenzyme Q monomethyl ether have a modulatory effect?. Nutrition 2009, 25:1157-1168. 10.1016/j.nut.2009.02.009, 19592219.
-
(2009)
Nutrition
, vol.25
, pp. 1157-1168
-
-
Safwat, G.M.1
Pisano, S.2
D'Amore, E.3
Borioni, G.4
Napolitano, M.5
Kamal, A.A.6
Ballanti, P.7
Botham, K.M.8
Bravo, E.9
-
130
-
-
33847665561
-
Protective role of melatonin and coenzyme Q10 in ochratoxin A toxicity in rat liver and kidney
-
17365150
-
Sutken E, Aral E, Ozdemir F, Uslu S, Alatas O, Colak O. Protective role of melatonin and coenzyme Q10 in ochratoxin A toxicity in rat liver and kidney. Int J Toxicol 2007, 26:81-87. 10.1080/10915810601122893, 17365150.
-
(2007)
Int J Toxicol
, vol.26
, pp. 81-87
-
-
Sutken, E.1
Aral, E.2
Ozdemir, F.3
Uslu, S.4
Alatas, O.5
Colak, O.6
-
131
-
-
24644463306
-
Enhanced anti-oxidant protection of liver membranes in long-lived rats fed on a coenzyme Q10-supplemented diet
-
16125350
-
Bello RI, Gomez-Diaz C, Buron MI, Alcain FJ, Navas P, Villalba JM. Enhanced anti-oxidant protection of liver membranes in long-lived rats fed on a coenzyme Q10-supplemented diet. Exp Gerontol 2005, 40:694-706. 10.1016/j.exger.2005.07.003, 16125350.
-
(2005)
Exp Gerontol
, vol.40
, pp. 694-706
-
-
Bello, R.I.1
Gomez-Diaz, C.2
Buron, M.I.3
Alcain, F.J.4
Navas, P.5
Villalba, J.M.6
-
132
-
-
57349096045
-
The metabolic syndrome
-
Cornier M-A, Dabelea D, Hernandez TL, Lindstrom RC, Steig AJ, Stob NR, Van Pelt RE, Wang H, Eckel RH. The metabolic syndrome. Endocrine Rev 2008, 29:777-822.
-
(2008)
Endocrine Rev
, vol.29
, pp. 777-822
-
-
Cornier, M.-A.1
Dabelea, D.2
Hernandez, T.L.3
Lindstrom, R.C.4
Steig, A.J.5
Stob, N.R.6
Van Pelt, R.E.7
Wang, H.8
Eckel, R.H.9
-
133
-
-
81455138113
-
Correlation between vitamin A, E, coenzyme Q-10 and degree of insulin resistance in obese and non-obese subjects
-
3208010, 22128213
-
Mehmetoglu I, Yerlikaya FH, Kurban S. Correlation between vitamin A, E, coenzyme Q-10 and degree of insulin resistance in obese and non-obese subjects. J Clin Biochem Nutr 2011, 49:159-163. 10.3164/jcbn.11-08, 3208010, 22128213.
-
(2011)
J Clin Biochem Nutr
, vol.49
, pp. 159-163
-
-
Mehmetoglu, I.1
Yerlikaya, F.H.2
Kurban, S.3
-
134
-
-
78650881903
-
Coenzyme Q as an antiadipogenic factor
-
21091355
-
Bour S, Carmona MC, Galinier A, Caspar-Bauguil S, Van Gaal L, Staels B, Penicaud L, Casteilla L. Coenzyme Q as an antiadipogenic factor. Antioxid Redox Signal 2011, 14:403-413. 10.1089/ars.2010.3350, 21091355.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 403-413
-
-
Bour, S.1
Carmona, M.C.2
Galinier, A.3
Caspar-Bauguil, S.4
Van Gaal, L.5
Staels, B.6
Penicaud, L.7
Casteilla, L.8
-
135
-
-
0032933626
-
ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose
-
84202, 10207099
-
Foretz M, Pacot C, Dugail I, Lemarchand P, Guichard C, le Lièpvre X, Berthelier-Lubrano C, Spiegelman B, Kim JB, Ferré P, Foufelle F. ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose. Mol Cell Biol 1999, 19:3760-3768. 84202, 10207099.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3760-3768
-
-
Foretz, M.1
Pacot, C.2
Dugail, I.3
Lemarchand, P.4
Guichard, C.5
le Lièpvre, X.6
Berthelier-Lubrano, C.7
Spiegelman, B.8
Kim, J.B.9
Ferré, P.10
Foufelle, F.11
-
136
-
-
0343986284
-
Drug delivery to mitochondria: the key to mitochondrial medicine
-
10699318
-
Murphy MP, Smith RA. Drug delivery to mitochondria: the key to mitochondrial medicine. Adv Drug Deliv Rev 2000, 41:235-250. 10.1016/S0169-409X(99)00069-1, 10699318.
-
(2000)
Adv Drug Deliv Rev
, vol.41
, pp. 235-250
-
-
Murphy, M.P.1
Smith, R.A.2
-
137
-
-
21744450416
-
Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury
-
15985532
-
Adlam VJ, Harrison JC, Porteous CM, James AM, Smith RA, Murphy MP, Sammut IA. Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury. FASEB J 2005, 19:1088-1095. 10.1096/fj.05-3718com, 15985532.
-
(2005)
FASEB J
, vol.19
, pp. 1088-1095
-
-
Adlam, V.J.1
Harrison, J.C.2
Porteous, C.M.3
James, A.M.4
Smith, R.A.5
Murphy, M.P.6
Sammut, I.A.7
-
138
-
-
56049120778
-
The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis
-
18845241
-
Lowes DA, Thottakam BM, Webster NR, Murphy MP, Galley HF. The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis. Free Radic Biol Med 2008, 45:1559-1565. 10.1016/j.freeradbiomed.2008.09.003, 18845241.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1559-1565
-
-
Lowes, D.A.1
Thottakam, B.M.2
Webster, N.R.3
Murphy, M.P.4
Galley, H.F.5
-
139
-
-
68549112975
-
Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy
-
19581509
-
Graham D, Huynh NN, Hamilton CA, Beattie E, Smith RAJ, Cochemé HM, Murphy MP, Dominiczak AF. Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy. Hypertension 2009, 54:322-328. 10.1161/HYPERTENSIONAHA.109.130351, 19581509.
-
(2009)
Hypertension
, vol.54
, pp. 322-328
-
-
Graham, D.1
Huynh, N.N.2
Hamilton, C.A.3
Beattie, E.4
Smith, R.A.J.5
Cochemé, H.M.6
Murphy, M.P.7
Dominiczak, A.F.8
-
140
-
-
77955095876
-
Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: prevention by the targeted antioxidant MitoQ
-
Vergeade A, Mulder P, Vendeville-Dehaudt C, Estour F, Fortin D, Ventura-Clapier R, Thuillez C, Monteil C. Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: prevention by the targeted antioxidant MitoQ. Free Radical Biol Med 2010, 49:748-756.
-
(2010)
Free Radical Biol Med
, vol.49
, pp. 748-756
-
-
Vergeade, A.1
Mulder, P.2
Vendeville-Dehaudt, C.3
Estour, F.4
Fortin, D.5
Ventura-Clapier, R.6
Thuillez, C.7
Monteil, C.8
-
141
-
-
79959538979
-
Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis
-
Chacko BK, Srivastava A, Johnson MS, Benavides GA, Chang MJ, Ye Y, Jhala N, Murphy MP, Kalyanaraman B, Darley-Usmar VM. Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis. J Hepatol 2011, 54:153-163.
-
(2011)
J Hepatol
, vol.54
, pp. 153-163
-
-
Chacko, B.K.1
Srivastava, A.2
Johnson, M.S.3
Benavides, G.A.4
Chang, M.J.5
Ye, Y.6
Jhala, N.7
Murphy, M.P.8
Kalyanaraman, B.9
Darley-Usmar, V.M.10
-
142
-
-
84856752588
-
The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice
-
Mercer JR, Yu E, Figg N, Cheng K-K, Prime TA, Griffin JL, Masoodi M, Vidal-Puig A, Murphy MP, Bennett MR. The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice. Free Radical Biol Med 2012, 52:841-849.
-
(2012)
Free Radical Biol Med
, vol.52
, pp. 841-849
-
-
Mercer, J.R.1
Yu, E.2
Figg, N.3
Cheng, K.-K.4
Prime, T.A.5
Griffin, J.L.6
Masoodi, M.7
Vidal-Puig, A.8
Murphy, M.P.9
Bennett, M.R.10
-
143
-
-
62549161327
-
Pharmacokinetic properties and metabolism of idebenone
-
Kutz K, Drewe J, Vankan P. Pharmacokinetic properties and metabolism of idebenone. J Neurol 2009, 256(Suppl 1):31-35.
-
(2009)
J Neurol
, vol.256
, pp. 31-35
-
-
Kutz, K.1
Drewe, J.2
Vankan, P.3
-
144
-
-
0022400051
-
Effects of idebenone (CV-2619) and its metabolites on respiratory activity and lipid peroxidation in brain mitochondria from rats and dogs
-
2871147
-
Sugiyama Y, Fujita T, Matsumoto M, Okamoto K, Imada I. Effects of idebenone (CV-2619) and its metabolites on respiratory activity and lipid peroxidation in brain mitochondria from rats and dogs. J Pharmacobiodyn 1985, 8:1006-1017. 10.1248/bpb1978.8.1006, 2871147.
-
(1985)
J Pharmacobiodyn
, vol.8
, pp. 1006-1017
-
-
Sugiyama, Y.1
Fujita, T.2
Matsumoto, M.3
Okamoto, K.4
Imada, I.5
-
145
-
-
0024563876
-
Inhibition of lipid peroxidation by idebenone in brain mitochondria in the presence of succinate
-
2764644
-
Suno M, Nagaoka A. Inhibition of lipid peroxidation by idebenone in brain mitochondria in the presence of succinate. Arch Gerontol Geriatr 1989, 8:291-297. 10.1016/0167-4943(89)90010-1, 2764644.
-
(1989)
Arch Gerontol Geriatr
, vol.8
, pp. 291-297
-
-
Suno, M.1
Nagaoka, A.2
-
146
-
-
0024556068
-
Effects of idebenone on lipid peroxidation and hemolysis in erythrocytes of stroke-prone spontaneously hypertensive rats
-
2764645
-
Suno M, Shibota M, Nagaoka A. Effects of idebenone on lipid peroxidation and hemolysis in erythrocytes of stroke-prone spontaneously hypertensive rats. Arch Gerontol Geriatr 1989, 8:307-311. 10.1016/0167-4943(89)90012-5, 2764645.
-
(1989)
Arch Gerontol Geriatr
, vol.8
, pp. 307-311
-
-
Suno, M.1
Shibota, M.2
Nagaoka, A.3
|