The reduced form of coenzyme Q10 mediates distinct effects on cholesterol metabolism at the transcriptional and metabolite level in SAMP1 mice

IUBMB Life

Volumn 62, Issue 11, 2010, Pages 812-818

  Schmelzer, Constance ^a   Okun, Jürgen G ^b   Haas, Dorothea ^b   Higuchi, Keiichi ^c   Sawashita, Jinko ^c   Mori, Masayuki ^c   Döring, Frank ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c SHINSHU UNIVERSITY   (Japan)

Author keywords

antioxidants; cholesterol; genomics; liver; Q10H2; SAMP1; senescence

Indexed keywords

DESMOSTEROL; LIVER X RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RETINOID X RECEPTOR; UBIDECARENONE;

ANIMAL EXPERIMENT; ARTICLE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; MASS FRAGMENTOGRAPHY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SENESCENCE ACCELERATED MOUSE;

ANIMALS; CHOLESTEROL; DESMOSTEROL; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENE EXPRESSION PROFILING; LIVER; MICE; OXIDATION-REDUCTION; PPAR ALPHA; RETINOID X RECEPTORS; UBIQUINONE;

ANIMALIA; MUS;

EID: 79952018447     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.388     Document Type: Article

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