Inflammation and obesity: STAMPing out insulin resistance?

Immunology and Cell Biology

Volumn 85, Issue 6, 2007, Pages 399-400

  Abedini, Andisheh ^b   Shoelson, Steven E ^a  

^a JOSLIN DIABETES CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; SIX TRANSMEMBRANE PROTEIN OF PROSTATE 2; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL EXPERIMENT; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INSULIN RESISTANCE; METABOLIC DISORDER; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NOTE; OBESITY; PATHOGENESIS; PROTEIN EXPRESSION;

ADIPOSE TISSUE; ANIMALS; HOMEOSTASIS; HUMANS; INFLAMMATION; INSULIN RESISTANCE; MEMBRANE PROTEINS; MICE; OBESITY; OXIDATIVE STRESS;

EID: 34548400409     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/sj.icb.7100107     Document Type: Note

References (5)

1. Hirosumi J, Tuncman G, Chang L, Gorgun CZ, Uysal KT, Maeda K et al. A central role for JNK in obesity and insulin resistance. Nature 2002; 420: 333-336.
2. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993; 259: 87-91.
3. Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 2006; 313: 1137-1140.
4. Wellen KE, Fucho R, Gregor MF, Furuhashi M, Morgan C, Lindstad T et al. Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis. Cell 2007; 129: 537-548.
5. Ohgami RS, Campagna DR, McDonald A, Fleming MD. The steap proteins are metalloreductases. Blood 2006; 108: 1388-1394.