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Volumn 55, Issue , 2014, Pages 38-50

Fifth lumbar spinal nerve injury causes neurochemical changes in corresponding as well as adjacent spinal segments: A possible mechanism underlying neuropathic pain

Author keywords

DRG; L5 nerve injury; Neuroplastic changes; Primary afferents; Spinal cord

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; ISOLECTIN B4; NEUROKININ 1 RECEPTOR; NEUROPEPTIDE Y; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE;

EID: 84897650681     PISSN: 08910618     EISSN: 18736300     Source Type: Journal    
DOI: 10.1016/j.jchemneu.2013.12.002     Document Type: Article
Times cited : (20)

References (87)
  • 1
    • 0029655582 scopus 로고    scopus 로고
    • Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain
    • Abbadie C., Brown J.L., Mantyh P.W., Basbaum A.I. Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain. Neuroscience 1996, 70:201-209.
    • (1996) Neuroscience , vol.70 , pp. 201-209
    • Abbadie, C.1    Brown, J.L.2    Mantyh, P.W.3    Basbaum, A.I.4
  • 3
    • 0035151069 scopus 로고    scopus 로고
    • Involvement of Na+ channels in pain pathways
    • Baker M.D., Wood J.N. Involvement of Na+ channels in pain pathways. Trends Pharmacol. Sci. 2001, 22:27-31.
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 27-31
    • Baker, M.D.1    Wood, J.N.2
  • 4
    • 0036977050 scopus 로고    scopus 로고
    • Peripheral axotomy induces only very limited sprouting of coarse myelinated afferents into inner lamina II of rat spinal cord
    • Bao L., Wang H.F., Cai H-J., Tong Y-G., Jin S.-X., Lu Y-J., Grant G., Hökfelt T., Zhang X. Peripheral axotomy induces only very limited sprouting of coarse myelinated afferents into inner lamina II of rat spinal cord. Eur. J. Neurosci. 2002, 16:175-185.
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 175-185
    • Bao, L.1    Wang, H.F.2    Cai, H.-J.3    Tong, Y.-G.4    Jin, S.-X.5    Lu, Y.-J.6    Grant, G.7    Hökfelt, T.8    Zhang, X.9
  • 6
    • 0023895875 scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • Bennett G.J., Xie Y.K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 1988, 33:87-107.
    • (1988) Pain , vol.33 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.K.2
  • 8
    • 0344013816 scopus 로고    scopus 로고
    • Selective neurokinin-1 receptor antagonists are anti-hyperalgesic in a model of neuropathic pain in the guinea-pig
    • Campbell E.A., Gentry C.T., Patel S., Panesar M.S., Walpole C.S., Urban L. Selective neurokinin-1 receptor antagonists are anti-hyperalgesic in a model of neuropathic pain in the guinea-pig. Neuroscience 1998, 87:527-532.
    • (1998) Neuroscience , vol.87 , pp. 527-532
    • Campbell, E.A.1    Gentry, C.T.2    Patel, S.3    Panesar, M.S.4    Walpole, C.S.5    Urban, L.6
  • 9
    • 33749061243 scopus 로고    scopus 로고
    • Mechanisms of neuropathic pain
    • Campbell J.N., Meyer R.A. Mechanisms of neuropathic pain. Neuron 2006, 52:77-92.
    • (2006) Neuron , vol.52 , pp. 77-92
    • Campbell, J.N.1    Meyer, R.A.2
  • 10
    • 67651048942 scopus 로고    scopus 로고
    • Neuropathic pain: a maladaptive response of the nervous system to damage
    • Costigan M., Scholz J., Woolf C.J. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu. Rev. Neurosci. 2009, 32:1-32.
    • (2009) Annu. Rev. Neurosci. , vol.32 , pp. 1-32
    • Costigan, M.1    Scholz, J.2    Woolf, C.J.3
  • 11
    • 0034255439 scopus 로고    scopus 로고
    • Spared nerve injury: an animal model of persistent peripheral neuropathic pain
    • Decosterd I., Woolf C.J. Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain 2000, 87:149-158.
    • (2000) Pain , vol.87 , pp. 149-158
    • Decosterd, I.1    Woolf, C.J.2
  • 12
    • 30844438395 scopus 로고    scopus 로고
    • Response of nerves to injury in relation to neuropathic pain
    • Elsevier Inc., London, S.B. McMahon, M. Koltzenburg (Eds.)
    • Devor M. Response of nerves to injury in relation to neuropathic pain. Wall Melzack's Textbook of Pain 2006, 905-927. Elsevier Inc., London. S.B. McMahon, M. Koltzenburg (Eds.).
    • (2006) Wall Melzack's Textbook of Pain , pp. 905-927
    • Devor, M.1
  • 13
    • 0032723079 scopus 로고    scopus 로고
    • Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain
    • Dib-Hajj S.D., Fjell J., Cummins T.R., Zheng Z., Fried K., LaMotte R., Black J.A., Waxman S.G. Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain 1999, 83:591-600.
    • (1999) Pain , vol.83 , pp. 591-600
    • Dib-Hajj, S.D.1    Fjell, J.2    Cummins, T.R.3    Zheng, Z.4    Fried, K.5    LaMotte, R.6    Black, J.A.7    Waxman, S.G.8
  • 14
    • 0025828959 scopus 로고
    • Differential regulation of calcitonin gene-related peptide (CGRP) in regenerating rat facial nucleus and dorsal root ganglion
    • Dumoulin F.L., Raivich G., Streit W.J., Kreutzberg G.W. Differential regulation of calcitonin gene-related peptide (CGRP) in regenerating rat facial nucleus and dorsal root ganglion. Eur. J. Neurosci. 1991, 3:338-342.
    • (1991) Eur. J. Neurosci. , vol.3 , pp. 338-342
    • Dumoulin, F.L.1    Raivich, G.2    Streit, W.J.3    Kreutzberg, G.W.4
  • 15
    • 0036700128 scopus 로고    scopus 로고
    • Contribution of the spared primary afferent neurons to the pathomechanisms of neuropathic pain
    • Fukuoka T., Noguchi K. Contribution of the spared primary afferent neurons to the pathomechanisms of neuropathic pain. Mol. Neurobiol. 2002, 26:57-67.
    • (2002) Mol. Neurobiol. , vol.26 , pp. 57-67
    • Fukuoka, T.1    Noguchi, K.2
  • 16
    • 0032188750 scopus 로고    scopus 로고
    • Change in mRNAs for neuropeptides and the GABA(A) receptor in dorsal root ganglion neurons in a rat experimental neuropathic pain model
    • Fukuoka T., Tokunaga A., Kondo E., Miki K., Tachibana T., Noguchi K. Change in mRNAs for neuropeptides and the GABA(A) receptor in dorsal root ganglion neurons in a rat experimental neuropathic pain model. Pain 1998, 78:13-26.
    • (1998) Pain , vol.78 , pp. 13-26
    • Fukuoka, T.1    Tokunaga, A.2    Kondo, E.3    Miki, K.4    Tachibana, T.5    Noguchi, K.6
  • 17
    • 84155172137 scopus 로고    scopus 로고
    • Re-evaluation of the phenotypic changes in L4 dorsal root ganglion neurons after L5 spinal nerve ligation
    • Fukuoka T., Yamanaka H., Kobayashi K., Okubo M., Miyoshi K., Dai Y., Noguchi K. Re-evaluation of the phenotypic changes in L4 dorsal root ganglion neurons after L5 spinal nerve ligation. Pain 2012, 153:68-79.
    • (2012) Pain , vol.153 , pp. 68-79
    • Fukuoka, T.1    Yamanaka, H.2    Kobayashi, K.3    Okubo, M.4    Miyoshi, K.5    Dai, Y.6    Noguchi, K.7
  • 18
    • 0342506832 scopus 로고    scopus 로고
    • Reorganization of the spinal dorsal horn in models of chronic pain: correlation with behaviour
    • Goff J.R., Burkey A.R., Goff D.J., Jasmin L. Reorganization of the spinal dorsal horn in models of chronic pain: correlation with behaviour. Neuroscience 1998, 82:559-574.
    • (1998) Neuroscience , vol.82 , pp. 559-574
    • Goff, J.R.1    Burkey, A.R.2    Goff, D.J.3    Jasmin, L.4
  • 19
    • 3042775311 scopus 로고    scopus 로고
    • Effects of spinal nerve ligation on immunohistochemically identified neurons in the L4 and L5 dorsal root ganglia of the rat
    • Hammond D.L., Ackerman L., Holdsworth R., Elzey B. Effects of spinal nerve ligation on immunohistochemically identified neurons in the L4 and L5 dorsal root ganglia of the rat. J. Comp. Neurol. 2004, 475:575-589.
    • (2004) J. Comp. Neurol. , vol.475 , pp. 575-589
    • Hammond, D.L.1    Ackerman, L.2    Holdsworth, R.3    Elzey, B.4
  • 20
    • 0038699312 scopus 로고    scopus 로고
    • Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain
    • Hofmann H.A., De Vry J., Siegling A., Spreyer P., Denzer D. Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain. Eur. J. Pharmacol. 2003, 470:17-25.
    • (2003) Eur. J. Pharmacol. , vol.470 , pp. 17-25
    • Hofmann, H.A.1    De Vry, J.2    Siegling, A.3    Spreyer, P.4    Denzer, D.5
  • 21
    • 0023484637 scopus 로고
    • Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy
    • Hökfelt T., Wiesenfeld-Hallin Z., Villar M., Melander T. Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy. Neurosci. Lett. 1987, 83:217-220.
    • (1987) Neurosci. Lett. , vol.83 , pp. 217-220
    • Hökfelt, T.1    Wiesenfeld-Hallin, Z.2    Villar, M.3    Melander, T.4
  • 22
    • 0028157337 scopus 로고
    • Messenger plasticity in primary sensory neurons following axotomy and its functional implications
    • Hökfelt T., Zhang X., Wiesenfeld-Hallin Z. Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci. 1994, 17:22-30.
    • (1994) Trends Neurosci. , vol.17 , pp. 22-30
    • Hökfelt, T.1    Zhang, X.2    Wiesenfeld-Hallin, Z.3
  • 23
    • 33746921499 scopus 로고    scopus 로고
    • Central consequences of peripheral nerve damage.
    • in: McMahon, S.B., Koltzenburg, M. (Eds.), Wall Melzack's Textbook of Pain. Elsevier Churchill Livingstone, London
    • Hökfelt, T., Zhang, X., Xu X-a, Wiesenfeld-Hallin, Z., 2006. Central consequences of peripheral nerve damage., in: McMahon, S.B., Koltzenburg, M. (Eds.), Wall Melzack's Textbook of Pain. Elsevier Churchill Livingstone, London, pp. 947-960.
    • (2006) , pp. 947-960
    • Hökfelt, T.1    Zhang, X.2    Xu, X.-A.3    Wiesenfeld-Hallin, Z.4
  • 25
    • 0034130227 scopus 로고    scopus 로고
    • Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons
    • Honore P., Rogers S.D., Schwei M.J., Salak-Johnson J.L., Luger N.M., Sabino M.C., Clohisy D.R., Mantyh P.W. Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons. Neuroscience 2000, 98:585-598.
    • (2000) Neuroscience , vol.98 , pp. 585-598
    • Honore, P.1    Rogers, S.D.2    Schwei, M.J.3    Salak-Johnson, J.L.4    Luger, N.M.5    Sabino, M.C.6    Clohisy, D.R.7    Mantyh, P.W.8
  • 26
    • 0034954583 scopus 로고    scopus 로고
    • VR1 protein expression increases in undamaged DRG neurons after partial nerve injury
    • Hudson L.J., Bevan S., Wotherspoon G., Gentry C., Fox A., Winter J. VR1 protein expression increases in undamaged DRG neurons after partial nerve injury. Eur. J. Neurosci. 2001, 13:2105-2114.
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 2105-2114
    • Hudson, L.J.1    Bevan, S.2    Wotherspoon, G.3    Gentry, C.4    Fox, A.5    Winter, J.6
  • 27
    • 33847236545 scopus 로고    scopus 로고
    • Upregulation of substance P in low-threshold myelinated afferents is not required for tactile allodynia in the chronic constriction injury and spinal nerve ligation models
    • Hughes D.I., Scott D.T., Riddell J.S., Todd A.J. Upregulation of substance P in low-threshold myelinated afferents is not required for tactile allodynia in the chronic constriction injury and spinal nerve ligation models. J. Neurosci. 2007, 27:2035-2044.
    • (2007) J. Neurosci. , vol.27 , pp. 2035-2044
    • Hughes, D.I.1    Scott, D.T.2    Riddell, J.S.3    Todd, A.J.4
  • 28
    • 0018392311 scopus 로고
    • Substance P: depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neurons
    • Jessell T., Tsunoo A., Kanazawa I., Otsuka M. Substance P: depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neurons. Brain Res. 1979, 168:247-259.
    • (1979) Brain Res. , vol.168 , pp. 247-259
    • Jessell, T.1    Tsunoo, A.2    Kanazawa, I.3    Otsuka, M.4
  • 29
    • 0242475309 scopus 로고    scopus 로고
    • Central sensitization and LTP: do pain and memory share similar mechanisms?
    • Ji R.-R., Kohno T., Moore K.A., Woolf C.J. Central sensitization and LTP: do pain and memory share similar mechanisms?. Trends Neurosci. 2003, 26:696-705.
    • (2003) Trends Neurosci. , vol.26 , pp. 696-705
    • Ji, R.-R.1    Kohno, T.2    Moore, K.A.3    Woolf, C.J.4
  • 30
    • 0030598184 scopus 로고    scopus 로고
    • AFGF, bFGF and NGF differentially regulate neuropeptide expression in dorsal root ganglia after axotomy and induce autotomy
    • Ji R.R., Zhang Q., Pettersson R.F., Hökfelt T. aFGF, bFGF and NGF differentially regulate neuropeptide expression in dorsal root ganglia after axotomy and induce autotomy. Regul. Pept. 1996, 66:179-189.
    • (1996) Regul. Pept. , vol.66 , pp. 179-189
    • Ji, R.R.1    Zhang, Q.2    Pettersson, R.F.3    Hökfelt, T.4
  • 31
    • 0037109674 scopus 로고    scopus 로고
    • Spinal neurons that possess the substance P receptor are required for the development of central sensitization
    • Khasabov S.G., Rogers S.D., Ghilardi J.R., Peters C.M., Mantyh P.W., Simone D.A. Spinal neurons that possess the substance P receptor are required for the development of central sensitization. J. Neurosci. 2002, 22:9086-9098.
    • (2002) J. Neurosci. , vol.22 , pp. 9086-9098
    • Khasabov, S.G.1    Rogers, S.D.2    Ghilardi, J.R.3    Peters, C.M.4    Mantyh, P.W.5    Simone, D.A.6
  • 32
    • 0026727999 scopus 로고
    • An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat
    • Kim S.H., Chung J.M. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 1992, 50:355-363.
    • (1992) Pain , vol.50 , pp. 355-363
    • Kim, S.H.1    Chung, J.M.2
  • 34
    • 0036145275 scopus 로고    scopus 로고
    • Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8
    • Lai J., Gold M.S., Kim C.S., Bian D., Ossipov M.H., Hunter J.C., Porreca F. Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8. Pain 2002, 95:143-152.
    • (2002) Pain , vol.95 , pp. 143-152
    • Lai, J.1    Gold, M.S.2    Kim, C.S.3    Bian, D.4    Ossipov, M.H.5    Hunter, J.C.6    Porreca, F.7
  • 35
    • 0033957307 scopus 로고    scopus 로고
    • Spontaneous activity of axotomized afferent neurons after L5 spinal nerve injury in rats
    • Liu X., Eschenfelder S., Blenk K.H., Jänig W., Häbler H. Spontaneous activity of axotomized afferent neurons after L5 spinal nerve injury in rats. Pain 2000, 84:309-318.
    • (2000) Pain , vol.84 , pp. 309-318
    • Liu, X.1    Eschenfelder, S.2    Blenk, K.H.3    Jänig, W.4    Häbler, H.5
  • 36
    • 0035869568 scopus 로고    scopus 로고
    • Upregulation of dorsal root ganglion (alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats
    • Luo Z.D., Chaplan S.R., Higuera E.S., Sorkin L.S., Stauderman K.A., Williams M.E., Yaksh T.L. Upregulation of dorsal root ganglion (alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats. J. Neurosci. 2001, 21:1868-1875.
    • (2001) J. Neurosci. , vol.21 , pp. 1868-1875
    • Luo, Z.D.1    Chaplan, S.R.2    Higuera, E.S.3    Sorkin, L.S.4    Stauderman, K.A.5    Williams, M.E.6    Yaksh, T.L.7
  • 37
    • 0031847771 scopus 로고    scopus 로고
    • Increase of calcitonin gene-related peptide immunoreactivity in the axonal fibers of the gracile nuclei of adult and aged rats after complete and partial sciatic nerve injuries
    • Ma W., Bisby M.A. Increase of calcitonin gene-related peptide immunoreactivity in the axonal fibers of the gracile nuclei of adult and aged rats after complete and partial sciatic nerve injuries. Exp. Neurol. 1998, 152:137-149.
    • (1998) Exp. Neurol. , vol.152 , pp. 137-149
    • Ma, W.1    Bisby, M.A.2
  • 38
    • 0032874158 scopus 로고    scopus 로고
    • Increased calcitonin gene-related peptide immunoreactivity in gracile nucleus after partial sciatic nerve injury: age-dependent and originating from spared sensory neurons
    • Ma W., Ramer M.S., Bisby M.A. Increased calcitonin gene-related peptide immunoreactivity in gracile nucleus after partial sciatic nerve injury: age-dependent and originating from spared sensory neurons. Exp. Neurol. 1999, 159:459-473.
    • (1999) Exp. Neurol. , vol.159 , pp. 459-473
    • Ma, W.1    Ramer, M.S.2    Bisby, M.A.3
  • 39
    • 0031775956 scopus 로고    scopus 로고
    • Partial sciatic nerve injury in the mouse as a model of neuropathic pain: behavioral and neuroanatomical correlates
    • Malmberg A.B., Basbaum A.I. Partial sciatic nerve injury in the mouse as a model of neuropathic pain: behavioral and neuroanatomical correlates. Pain 1998, 76:215-222.
    • (1998) Pain , vol.76 , pp. 215-222
    • Malmberg, A.B.1    Basbaum, A.I.2
  • 40
    • 4544233776 scopus 로고    scopus 로고
    • Setting the tone: superficial dorsal horn projection neurons regulate pain sensitivity
    • Mantyh P.W., Hunt S.P. Setting the tone: superficial dorsal horn projection neurons regulate pain sensitivity. Trends Neurosci. 2004, 27:582-584.
    • (2004) Trends Neurosci. , vol.27 , pp. 582-584
    • Mantyh, P.W.1    Hunt, S.P.2
  • 41
    • 0027936177 scopus 로고
    • Altered tachykinin expression by dorsal root ganglion neurons in a rat model of neuropathic pain
    • Marchand J.E., Wurm W.H., Kato T., Kream R.M. Altered tachykinin expression by dorsal root ganglion neurons in a rat model of neuropathic pain. Pain 1994, 58:219-231.
    • (1994) Pain , vol.58 , pp. 219-231
    • Marchand, J.E.1    Wurm, W.H.2    Kato, T.3    Kream, R.M.4
  • 42
    • 0029880285 scopus 로고    scopus 로고
    • Neurokinin-1 receptors on lumbar spinothalamic neurons in the rat
    • Marshall G.E., Shehab S.A., Spike R.C., Todd A.J. Neurokinin-1 receptors on lumbar spinothalamic neurons in the rat. Neuroscience 1996, 72:255-263.
    • (1996) Neuroscience , vol.72 , pp. 255-263
    • Marshall, G.E.1    Shehab, S.A.2    Spike, R.C.3    Todd, A.J.4
  • 43
    • 0021162587 scopus 로고
    • Effect of peripheral nerve section and nerve crush on spinal cord neuropeptides in the rat; increased VIP and PHI in the dorsal horn
    • McGregor G.P., Gibson S.J., Sabate I.M., Blank M.A., Christofides N.D., Wall P.D., Polak J.M., Bloom S.R. Effect of peripheral nerve section and nerve crush on spinal cord neuropeptides in the rat; increased VIP and PHI in the dorsal horn. Neuroscience 1984, 13:207-216.
    • (1984) Neuroscience , vol.13 , pp. 207-216
    • McGregor, G.P.1    Gibson, S.J.2    Sabate, I.M.3    Blank, M.A.4    Christofides, N.D.5    Wall, P.D.6    Polak, J.M.7    Bloom, S.R.8
  • 44
    • 0033103354 scopus 로고    scopus 로고
    • Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy
    • Michael G.J., Priestley J.V. Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy. J. Neurosci. 1999, 19:1844-1854.
    • (1999) J. Neurosci. , vol.19 , pp. 1844-1854
    • Michael, G.J.1    Priestley, J.V.2
  • 45
    • 0342275181 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide increase in the rat spinal dorsal horn and dorsal column nucleus following peripheral nerve injury: up-regulation in a subpopulation of primary afferent sensory neurons
    • Miki K., Fukuoka T., Tokunaga A., Noguchi K. Calcitonin gene-related peptide increase in the rat spinal dorsal horn and dorsal column nucleus following peripheral nerve injury: up-regulation in a subpopulation of primary afferent sensory neurons. Neuroscience 1998, 82:1243-1252.
    • (1998) Neuroscience , vol.82 , pp. 1243-1252
    • Miki, K.1    Fukuoka, T.2    Tokunaga, A.3    Noguchi, K.4
  • 46
    • 0030465638 scopus 로고    scopus 로고
    • Early decline and late restoration of spinal cord binding and transganglionic transport of isolectin B4 from Griffonia simplicifolia I after peripheral nerve transection or crush
    • Molander C., Wang H.F., Rivero-Melián C., Grant G. Early decline and late restoration of spinal cord binding and transganglionic transport of isolectin B4 from Griffonia simplicifolia I after peripheral nerve transection or crush. Restor. Neurol. Neurosci. 1996, 10:123-133.
    • (1996) Restor. Neurol. Neurosci. , vol.10 , pp. 123-133
    • Molander, C.1    Wang, H.F.2    Rivero-Melián, C.3    Grant, G.4
  • 47
    • 0030839073 scopus 로고    scopus 로고
    • Cells in laminae III and IV of the rat spinal cord that possess the neurokinin-1 receptor and have dorsally directed dendrites receive a major synaptic input from tachykinin-containing primary afferents
    • Naim M., Spike R.C., Watt C., Shehab S.A., Todd A.J. Cells in laminae III and IV of the rat spinal cord that possess the neurokinin-1 receptor and have dorsally directed dendrites receive a major synaptic input from tachykinin-containing primary afferents. J. Neurosci. 1997, 17:5536-5548.
    • (1997) J. Neurosci. , vol.17 , pp. 5536-5548
    • Naim, M.1    Spike, R.C.2    Watt, C.3    Shehab, S.A.4    Todd, A.J.5
  • 48
    • 34447635901 scopus 로고    scopus 로고
    • Neural plasticity after peripheral nerve injury and regeneration
    • Navarro X., Vivó M., Valero-Cabré A. Neural plasticity after peripheral nerve injury and regeneration. Prog. Neurobiol. 2007, 82:163-201.
    • (2007) Prog. Neurobiol. , vol.82 , pp. 163-201
    • Navarro, X.1    Vivó, M.2    Valero-Cabré, A.3
  • 49
    • 0035500748 scopus 로고    scopus 로고
    • Dorsal root ganglion neurons show increased expression of the calcium channel alpha2delta-1 subunit following partial sciatic nerve injury
    • Newton R.A., Bingham S., Case P.C., Sanger G.J., Lawson S.N. Dorsal root ganglion neurons show increased expression of the calcium channel alpha2delta-1 subunit following partial sciatic nerve injury. Brain Res. Mol. Brain Res. 2001, 95:1-8.
    • (2001) Brain Res. Mol. Brain Res. , vol.95 , pp. 1-8
    • Newton, R.A.1    Bingham, S.2    Case, P.C.3    Sanger, G.J.4    Lawson, S.N.5
  • 51
    • 0028334902 scopus 로고
    • Axotomy induces preprotachykinin gene expression in a subpopulation of dorsal root ganglion neurons
    • Noguchi K., Dubner R., De Leon M., Senba E., Ruda M.A. Axotomy induces preprotachykinin gene expression in a subpopulation of dorsal root ganglion neurons. J. Neurosci. Res. 1994, 37:596-603.
    • (1994) J. Neurosci. Res. , vol.37 , pp. 596-603
    • Noguchi, K.1    Dubner, R.2    De Leon, M.3    Senba, E.4    Ruda, M.A.5
  • 52
    • 0028800179 scopus 로고
    • Substance P induced by peripheral nerve injury in primary afferent sensory neurons and its effect on dorsal column nucleus neurons
    • Noguchi K., Kawai Y., Fukuoka T., Senba E., Miki K. Substance P induced by peripheral nerve injury in primary afferent sensory neurons and its effect on dorsal column nucleus neurons. J. Neurosci. 1995, 15:7633-7643.
    • (1995) J. Neurosci. , vol.15 , pp. 7633-7643
    • Noguchi, K.1    Kawai, Y.2    Fukuoka, T.3    Senba, E.4    Miki, K.5
  • 53
    • 0025342422 scopus 로고
    • Alpha-CGRP and beta-CGRP mRNAs are differentially regulated in the rat spinal cord and dorsal root ganglion
    • Noguchi K., Senba E., Morita Y., Sato M., Tohyama M. Alpha-CGRP and beta-CGRP mRNAs are differentially regulated in the rat spinal cord and dorsal root ganglion. Brain Res. Mol. Brain Res. 1990, 7:299-304.
    • (1990) Brain Res. Mol. Brain Res. , vol.7 , pp. 299-304
    • Noguchi, K.1    Senba, E.2    Morita, Y.3    Sato, M.4    Tohyama, M.5
  • 54
    • 33746407786 scopus 로고    scopus 로고
    • Mechanisms of experimental neuropathic pain: integration from animal models
    • Elsevier Inc., London, S.B. McMahon, M. Koltzenburg (Eds.)
    • Ossipov M.H., Lai J., Porreca F. Mechanisms of experimental neuropathic pain: integration from animal models. Wall Melzack's Textbook of Pain 2006, 929-946. Elsevier Inc., London. S.B. McMahon, M. Koltzenburg (Eds.).
    • (2006) Wall Melzack's Textbook of Pain , pp. 929-946
    • Ossipov, M.H.1    Lai, J.2    Porreca, F.3
  • 55
    • 0030042723 scopus 로고    scopus 로고
    • Effects of peripheral axotomy on neuropeptides and nitric oxide synthase in dorsal root ganglia and spinal cord of the guinea pig: an immunohistochemical study
    • Rydh-Rinder M., Holmberg K., Elfvin L.G., Wiesenfeld-Hallin Z., Hokfelt T. Effects of peripheral axotomy on neuropeptides and nitric oxide synthase in dorsal root ganglia and spinal cord of the guinea pig: an immunohistochemical study. Brain Res. 1996, 707:180-188.
    • (1996) Brain Res. , vol.707 , pp. 180-188
    • Rydh-Rinder, M.1    Holmberg, K.2    Elfvin, L.G.3    Wiesenfeld-Hallin, Z.4    Hokfelt, T.5
  • 56
    • 50049118015 scopus 로고    scopus 로고
    • Nociceptive behavior in animal models for peripheral neuropathy: spinal and supraspinal mechanisms
    • Saadé N.E., Jabbur S.J. Nociceptive behavior in animal models for peripheral neuropathy: spinal and supraspinal mechanisms. Prog. Neurobiol. 2008, 86:22-47.
    • (2008) Prog. Neurobiol. , vol.86 , pp. 22-47
    • Saadé, N.E.1    Jabbur, S.J.2
  • 57
    • 1842633517 scopus 로고    scopus 로고
    • Co-localization of endomorphin-2 and substance P in primary afferent nociceptors and effects of injury: a light and electron microscopic study in the rat
    • Sanderson Nydahl K., Skinner K., Julius D., Basbaum A.I. Co-localization of endomorphin-2 and substance P in primary afferent nociceptors and effects of injury: a light and electron microscopic study in the rat. Eur. J. Neurosci. 2004, 19:1789-1799.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1789-1799
    • Sanderson Nydahl, K.1    Skinner, K.2    Julius, D.3    Basbaum, A.I.4
  • 58
    • 67349202612 scopus 로고    scopus 로고
    • Models and mechanisms of hyperalgesia and allodynia
    • Sandkühler J. Models and mechanisms of hyperalgesia and allodynia. Physiol. Rev. 2009, 89:707-758.
    • (2009) Physiol. Rev. , vol.89 , pp. 707-758
    • Sandkühler, J.1
  • 59
    • 0037450494 scopus 로고    scopus 로고
    • Transganglionic transport of choleragenoid by capsaicin-sensitive C-fibre afferents to the substantia gelatinosa of the spinal dorsal horn after peripheral nerve section
    • Sántha P., Jancsó G. Transganglionic transport of choleragenoid by capsaicin-sensitive C-fibre afferents to the substantia gelatinosa of the spinal dorsal horn after peripheral nerve section. Neuroscience 2003, 116:621-627.
    • (2003) Neuroscience , vol.116 , pp. 621-627
    • Sántha, P.1    Jancsó, G.2
  • 60
    • 0025167399 scopus 로고
    • A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury
    • Seltzer Z., Dubner R., Shir Y. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 1990, 43:205-218.
    • (1990) Pain , vol.43 , pp. 205-218
    • Seltzer, Z.1    Dubner, R.2    Shir, Y.3
  • 61
    • 43049117876 scopus 로고    scopus 로고
    • Unmyelinated primary afferents from adjacent spinal nerves intermingle in the spinal dorsal horn: a possible mechanism contributing to neuropathic pain
    • Shehab, S.a S., Al-Marashda K., Al-Zahmi A., Abdul-Kareem A., Al-Sultan M.A. Unmyelinated primary afferents from adjacent spinal nerves intermingle in the spinal dorsal horn: a possible mechanism contributing to neuropathic pain. Brain Res. 2008, 1208:111-119.
    • (2008) Brain Res. , vol.1208 , pp. 111-119
    • Shehab, S.A.S.1    Al-Marashda, K.2    Al-Zahmi, A.3    Abdul-Kareem, A.4    Al-Sultan, M.A.5
  • 62
    • 0022448885 scopus 로고
    • Vasoactive intestinal polypeptide (VIP) increases in the spinal cord after peripheral axotomy of the sciatic nerve originate from primary afferent neurons
    • Shehab S.A., Atkinson M.E. Vasoactive intestinal polypeptide (VIP) increases in the spinal cord after peripheral axotomy of the sciatic nerve originate from primary afferent neurons. Brain Res. 1986, 372:37-44.
    • (1986) Brain Res. , vol.372 , pp. 37-44
    • Shehab, S.A.1    Atkinson, M.E.2
  • 63
    • 0022574861 scopus 로고
    • Vasoactive intestinal polypeptide increases in areas of the dorsal horn of the spinal cord from which other neuropeptides are depleted following peripheral axotomy
    • Shehab S.A., Atkinson M.E. Vasoactive intestinal polypeptide increases in areas of the dorsal horn of the spinal cord from which other neuropeptides are depleted following peripheral axotomy. Exp. Brain Res. 1986, 62:422-430.
    • (1986) Exp. Brain Res. , vol.62 , pp. 422-430
    • Shehab, S.A.1    Atkinson, M.E.2
  • 64
    • 0022450042 scopus 로고
    • The origins of the sciatic nerve and changes in neuropeptides after axotomy: a double labelling study using retrograde transport of true blue and vasoactive intestinal polypeptide immunohistochemistry
    • Shehab S.A., Atkinson M.E., Payne J.N. The origins of the sciatic nerve and changes in neuropeptides after axotomy: a double labelling study using retrograde transport of true blue and vasoactive intestinal polypeptide immunohistochemistry. Brain Res. 1986, 376:180-185.
    • (1986) Brain Res. , vol.376 , pp. 180-185
    • Shehab, S.A.1    Atkinson, M.E.2    Payne, J.N.3
  • 65
    • 70350133700 scopus 로고    scopus 로고
    • Acute and chronic sectioning of fifth lumbar spinal nerve has equivalent effects on the primary afferents of sciatic nerve in rat spinal cord
    • Shehab S.A.S. Acute and chronic sectioning of fifth lumbar spinal nerve has equivalent effects on the primary afferents of sciatic nerve in rat spinal cord. J. Comp. Neurol. 2009, 517:481-492.
    • (2009) J. Comp. Neurol. , vol.517 , pp. 481-492
    • Shehab, S.A.S.1
  • 66
    • 84897603732 scopus 로고    scopus 로고
    • Fifth lumbar spinal nerve injury causes neurochemical changes in corresponding as well as adjacent spinal segments. A possible mechanism underlying neuropathic pain
    • Shehab S.A.S. Fifth lumbar spinal nerve injury causes neurochemical changes in corresponding as well as adjacent spinal segments. A possible mechanism underlying neuropathic pain. 8th IBRO World Congress of Neuroscience 2011.
    • (2011) 8th IBRO World Congress of Neuroscience
    • Shehab, S.A.S.1
  • 67
    • 0037469931 scopus 로고    scopus 로고
    • Evidence against cholera toxin B subunit as a reliable tracer for sprouting of primary afferents following peripheral nerve injury
    • Shehab S.A.S., Spike R.C., Todd A.J. Evidence against cholera toxin B subunit as a reliable tracer for sprouting of primary afferents following peripheral nerve injury. Brain Res. 2003, 964:218-227.
    • (2003) Brain Res. , vol.964 , pp. 218-227
    • Shehab, S.A.S.1    Spike, R.C.2    Todd, A.J.3
  • 68
    • 2642572705 scopus 로고    scopus 로고
    • Do central terminals of intact myelinated primary afferents sprout into the superficial dorsal horn of rat spinal cord after injury to a neighboring peripheral nerve?
    • Shehab S.A.S., Spike R.C., Todd A.J. Do central terminals of intact myelinated primary afferents sprout into the superficial dorsal horn of rat spinal cord after injury to a neighboring peripheral nerve?. J. Comp. Neurol. 2004, 474:427-437.
    • (2004) J. Comp. Neurol. , vol.474 , pp. 427-437
    • Shehab, S.A.S.1    Spike, R.C.2    Todd, A.J.3
  • 70
    • 0035800216 scopus 로고    scopus 로고
    • Delayed administration of NGF reverses nerve injury induced central alterations of primary afferents
    • Siri C.R., Shortland P.J., Grant G., Olivius N.P. Delayed administration of NGF reverses nerve injury induced central alterations of primary afferents. Neuroreport 2001, 12:1899-1902.
    • (2001) Neuroreport , vol.12 , pp. 1899-1902
    • Siri, C.R.1    Shortland, P.J.2    Grant, G.3    Olivius, N.P.4
  • 71
    • 0000979905 scopus 로고
    • Neuronal and synaptic arrangement in the substantia gelatinosa Rolandi
    • Szentagothai J. Neuronal and synaptic arrangement in the substantia gelatinosa Rolandi. J. Comp. Neurol. 1964, 122:219-239.
    • (1964) J. Comp. Neurol. , vol.122 , pp. 219-239
    • Szentagothai, J.1
  • 72
    • 0023865648 scopus 로고
    • Transganglionic regulation and fine structural localization of lectin-reactive carbohydrate epitopes in primary sensory neurons of the rat
    • Tajti J., Fischer J., Knyihár-Csillik E., Csillik B. Transganglionic regulation and fine structural localization of lectin-reactive carbohydrate epitopes in primary sensory neurons of the rat. Histochemistry 1988, 88:213-218.
    • (1988) Histochemistry , vol.88 , pp. 213-218
    • Tajti, J.1    Fischer, J.2    Knyihár-Csillik, E.3    Csillik, B.4
  • 73
    • 2442660514 scopus 로고    scopus 로고
    • Neurokinin-1 receptor gene expression in the mouse dorsal horn increases with neuropathic pain
    • Taylor B.K., McCarson K.E. Neurokinin-1 receptor gene expression in the mouse dorsal horn increases with neuropathic pain. J. Pain 2004, 5:71-76.
    • (2004) J. Pain , vol.5 , pp. 71-76
    • Taylor, B.K.1    McCarson, K.E.2
  • 74
    • 0034052838 scopus 로고    scopus 로고
    • Neurokinin 1 receptor expression by neurons in laminae I, III and IV of the rat spinal dorsal horn that project to the brainstem
    • Todd A.J., McGill M.M., Shehab S.A. Neurokinin 1 receptor expression by neurons in laminae I, III and IV of the rat spinal dorsal horn that project to the brainstem. Eur. J. Neurosci. 2000, 12:689-700.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 689-700
    • Todd, A.J.1    McGill, M.M.2    Shehab, S.A.3
  • 75
    • 0033535120 scopus 로고    scopus 로고
    • Increased uptake and transport of cholera toxin B-subunit in dorsal root ganglion neurons after peripheral axotomy: possible implications for sensory sprouting
    • Tong Y.G., Wang H.F., Ju G., Grant G., Hökfelt T., Zhang X. Increased uptake and transport of cholera toxin B-subunit in dorsal root ganglion neurons after peripheral axotomy: possible implications for sensory sprouting. J. Comp. Neurol. 1999, 404:143-158.
    • (1999) J. Comp. Neurol. , vol.404 , pp. 143-158
    • Tong, Y.G.1    Wang, H.F.2    Ju, G.3    Grant, G.4    Hökfelt, T.5    Zhang, X.6
  • 76
    • 0033956898 scopus 로고    scopus 로고
    • Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury
    • Tsujino H., Kondo E., Fukuoka T., Dai Y., Tokunaga A., Miki K., Yonenobu K., Ochi T., Noguchi K. Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury. Mol. Cell. Neurosci. 2000, 15:170-182.
    • (2000) Mol. Cell. Neurosci. , vol.15 , pp. 170-182
    • Tsujino, H.1    Kondo, E.2    Fukuoka, T.3    Dai, Y.4    Tokunaga, A.5    Miki, K.6    Yonenobu, K.7    Ochi, T.8    Noguchi, K.9
  • 77
    • 0026788227 scopus 로고
    • Peripheral injury and anterograde transport of wheat germ agglutinin-horse radish peroxidase to the spinal cord
    • Valtschanoff J.G., Weinberg R.J., Rustioni A. Peripheral injury and anterograde transport of wheat germ agglutinin-horse radish peroxidase to the spinal cord. Neuroscience 1992, 50:685-696.
    • (1992) Neuroscience , vol.50 , pp. 685-696
    • Valtschanoff, J.G.1    Weinberg, R.J.2    Rustioni, A.3
  • 79
    • 0025763682 scopus 로고
    • Increased neuropeptide Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy
    • Wakisaka S., Kajander K.C., Bennett G.J. Increased neuropeptide Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy. Neurosci. Lett. 1991, 124:200-203.
    • (1991) Neurosci. Lett. , vol.124 , pp. 200-203
    • Wakisaka, S.1    Kajander, K.C.2    Bennett, G.J.3
  • 80
    • 0037063697 scopus 로고    scopus 로고
    • Chronic neuropathic pain is accompanied by global changes in gene expression and shares pathobiology with neurodegenerative diseases
    • Wang H., Sun H., Della Penna K., Benz R.J., Xu J., Gerhold D.L., Holder D.J., Koblan K.S. Chronic neuropathic pain is accompanied by global changes in gene expression and shares pathobiology with neurodegenerative diseases. Neuroscience 2002, 114:529-546.
    • (2002) Neuroscience , vol.114 , pp. 529-546
    • Wang, H.1    Sun, H.2    Della Penna, K.3    Benz, R.J.4    Xu, J.5    Gerhold, D.L.6    Holder, D.J.7    Koblan, K.S.8
  • 81
    • 33744900904 scopus 로고    scopus 로고
    • Time course of substance P expression in dorsal root ganglia following complete spinal nerve transection
    • Weissner W., Winterson B.J., Stuart-Tilley A., Devor M., Bove G.M. Time course of substance P expression in dorsal root ganglia following complete spinal nerve transection. J. Comp. Neurol. 2006, 497:78-87.
    • (2006) J. Comp. Neurol. , vol.497 , pp. 78-87
    • Weissner, W.1    Winterson, B.J.2    Stuart-Tilley, A.3    Devor, M.4    Bove, G.M.5
  • 85
    • 0029071039 scopus 로고
    • Effect of growth factors on substance P mRNA expression in axotomized dorsal root ganglia
    • Zhang Q., Ji R.R., Lindsay R., Hökfelt T. Effect of growth factors on substance P mRNA expression in axotomized dorsal root ganglia. Neuroreport 1995, 6:1309-1312.
    • (1995) Neuroreport , vol.6 , pp. 1309-1312
    • Zhang, Q.1    Ji, R.R.2    Lindsay, R.3    Hökfelt, T.4
  • 86
    • 0028921680 scopus 로고
    • Secretory pathways of neuropeptides in rat lumbar dorsal root ganglion neurons and effects of peripheral axotomy
    • Zhang X., Aman K., Hökfelt T. Secretory pathways of neuropeptides in rat lumbar dorsal root ganglion neurons and effects of peripheral axotomy. J. Comp. Neurol. 1995, 352:481-500.
    • (1995) J. Comp. Neurol. , vol.352 , pp. 481-500
    • Zhang, X.1    Aman, K.2    Hökfelt, T.3


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