Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF

Molecular Therapy

Volumn 13, Issue 6, 2006, Pages 1101-1109

  Pezet, Sophie ^a   Krzyzanowska, Agnieszka ^a   Wong, Liang Fong ^b   Grist, John ^a   Mazarakis, Nicholas D ^b   Georgievska, Biljana ^c   McMahon, Stephen B ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b OXFORD BIOMEDICA UK LTD   (United Kingdom)

^c LUND UNIVERSITY   (Sweden)

Author keywords

ATF 3; IB4; neuroprotection; spinal cord; survival; trophic factor

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; BETA GALACTOSIDASE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; ATF3 PROTEIN, RAT; LECTIN;

ANALGESIC ACTIVITY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG TARGETING; GENE EXPRESSION; GLIA CELL; HUMAN; HUMAN CELL; HYPERALGESIA; NERVE CELL; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; RAT; SPINAL CORD DORSAL HORN; SPINAL GANGLION; TRANSGENE; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; ANIMAL; DISEASE MODEL; DRUG EFFECT; EQUINE INFECTIOUS ANEMIA VIRUS; GENE THERAPY; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS; LENTIVIRINAE; LIGATION; METABOLISM; METHODOLOGY; NEURALGIA; PATHOLOGY; SPINAL CORD; SPINAL NERVE; WISTAR RAT;

RODENTIA;

ACTIVATING TRANSCRIPTION FACTOR 3; ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; GENE THERAPY; GENETIC VECTORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HIV; INFECTIOUS ANEMIA VIRUS, EQUINE; LECTINS; LENTIVIRUS; LIGATION; NEURALGIA; RATS; RATS, WISTAR; SPINAL CORD; SPINAL NERVES; TRANSDUCTION, GENETIC;

EID: 33746234869     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.11.026     Document Type: Article

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