Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1

Molecular Microbiology

Volumn 91, Issue 3, 2014, Pages 438-451

  Vilaça, Rita ^a,b   Silva, Elísio ^a,b   Nadais, André ^a,b   Teixeira, Vítor ^a,b   Matmati, Nabil ^c   Gaifem, Joana ^a   Hannun, Yusuf A ^c   Sá Miranda, Maria Clara ^a   Costa, Vítor ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c Stony Brook School of Dental Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; CYTOCHROME C OXIDASE; GLUTATHIONE; HYDROGEN PEROXIDE; MEMBRANE PROTEIN; NCR1P PROTEIN; PKH1P KINASE; PROTEIN KINASE; S6 KINASE; SCH9P PROTEIN; SPHINGOLIPID; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; 3 PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE; NCR1 PROTEIN, S CEREVISIAE; PKH1 PROTEIN, S CEREVISIAE; PROTEIN SERINE THREONINE KINASE; SACCHAROMYCES CEREVISIAE PROTEIN; SCH9 PROTEIN, S CEREVISIAE; VESICULAR TRANSPORT PROTEIN;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; LIFESPAN; MITOCHONDRION; NIEMANN PICK DISEASE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; SPHINGOLIPID METABOLISM; YEAST CELL; DRUG EFFECT; GENE DELETION; GENETICS; METABOLISM; PHYSIOLOGY;

MAMMALIA;

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES; GENE DELETION; MITOCHONDRIA; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPHINGOLIPIDS; VESICULAR TRANSPORT PROTEINS;

EID: 84908101723     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12470     Document Type: Article

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