Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan

Aging Cell

Volumn 12, Issue 5, 2013, Pages 833-841

  Liu, Jun ^a,b   Huang, Xinhe ^b   Withers, Bradley R ^b   Blalock, Eric ^b   Liu, Ke ^a   Dickson, Robert C ^b  

^a SICHUAN UNIVERSITY   (China)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Aging; AMPK; Myriocin; S6 kinase; Sphingolipids; TORC1

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; SPHINGOLIPID; THERMOZYMOCIDIN;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CALORIC RESTRICTION; CARBON METABOLISM; CONTROLLED STUDY; GENE EXPRESSION; GLOBAL CHANGE; LIFESPAN; LIPOGENESIS; LOW DRUG DOSE; MODULATION; NITROGEN METABOLISM; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REPORTER GENE; STRESS; YEAST;

EUKARYOTA; MAMMALIA;

AGING; AMPK; MYRIOCIN; S6 KINASE; SPHINGOLIPIDS; TORC1;

ANIMALS; ANTIFUNGAL AGENTS; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION REGULATION, FUNGAL; LONGEVITY; SIGNAL TRANSDUCTION; SPHINGOLIPIDS; YEASTS;

EID: 84883765669     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12107     Document Type: Article

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