SUMOylation protects against IL-1β-induced apoptosis in INS-1 832/13 cells and human islets

American Journal of Physiology - Endocrinology and Metabolism

Volumn 307, Issue 8, 2014, Pages E664-E673

  Hajmrle, Catherine ^a   Ferdaoussi, Mourad ^a   Plummer, Gregory ^a   Spigelman, Aliya F ^a   Lai, Krista ^a   Fox, Jocelyn E Manning ^a   MacDonald, Patrick E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Inducible nitric oxide synthase; Islets of Langerhans; SENP1; Sentrin SUMO specific protease 1; SUMOylation

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; SMALL INTERFERING RNA; SUMO 1 PROTEIN; IL1B PROTEIN, HUMAN; INSULIN; PROTEINASE; RECOMBINANT PROTEIN; SENP1 PROTEIN, HUMAN; SUMO1 PROTEIN, HUMAN;

ADULT; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; ENDOPLASMIC RETICULUM STRESS; EXOCYTOSIS; HUMAN; HUMAN CELL; INSULIN RELEASE; MALE; MOUSE; NICK END LABELING; NONHUMAN; NORMAL HUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PROTEIN CLEAVAGE; SUMOYLATION; UPREGULATION; ANIMAL; C57BL MOUSE; CALCIUM SIGNALING; CELL CULTURE; CELL LINE; CHEMISTRY; CYTOLOGY; DOWN REGULATION; GENETICS; METABOLISM; MIDDLE AGED; RAT; RNA INTERFERENCE; SECRETION (PROCESS); TISSUE CULTURE TECHNIQUE;

ANIMALS; APOPTOSIS; CALCIUM SIGNALING; CELL LINE; CELLS, CULTURED; DOWN-REGULATION; ENDOPEPTIDASES; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INTERLEUKIN-1BETA; ISLETS OF LANGERHANS; MALE; MICE, INBRED C57BL; MIDDLE AGED; RATS; RECOMBINANT PROTEINS; RNA INTERFERENCE; SUMO-1 PROTEIN; SUMOYLATION; TISSUE CULTURE TECHNIQUES; UP-REGULATION;

EID: 84908050954     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00168.2014     Document Type: Article

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