Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice

Diabetes

Volumn 56, Issue 5, 2007, Pages 1259-1267

  Rivas Carrillo, Jorge D ^a   Soto Gutierrez, Alejandro ^a   Navarro Alvarez, Nalu ^a   Noguchi, Hirofumi ^b   Okitsu, Teru ^c   Chen, Yong ^a   Yuasa, Takeshi ^a   Tanaka, Kimiaki ^a   Narushima, Michiki ^a   Miki, Atsushi ^a   Misawa, Haruo ^a   Tabata, Yasuhiko ^d   Jun, Hee Sook ^e,f   Matsumoto, Shinichi ^g   Fox, Ira J ^h   Tanaka, Noriaki ^a   Kobayashi, Naoya ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e The Chicago Medical College   (United States)

^f Chosun University   (South Korea)

^g FUJITA HEALTH UNIVERSITY   (Japan)

^h UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; PENTAPEPTIDE; PROTEIN INHIBITOR; STREPTOZOCIN; UNCLASSIFIED DRUG; VALYLPROLYLMETHIONYLLEUCYLLYSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; COLD ISCHEMIA; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET CELL FUNCTION; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; STREPTOZOCIN DIABETES; SURVIVAL RATE; SURVIVAL TIME; UPREGULATION;

ANIMALS; ANNEXIN A5; APOPTOSIS; DIABETES MELLITUS, TYPE 1; FEMALE; GENE EXPRESSION REGULATION; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; OLIGOPEPTIDES; PROTO-ONCOGENE PROTEINS C-BCL-2; TISSUE DONORS; TRANSPLANTATION, ISOGENEIC; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 34248191271     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-1679     Document Type: Article

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