MiR-21 simultaneously regulates ERK1 signaling in HSC activation and hepatocyte EMT in hepatic fibrosis

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Zhao, Juan ^a   Tang, Nan ^a   Wu, Kaiming ^a   Dai, Weiping ^a   Ye, Changhong ^a   Shi, Jian ^a   Zhang, Junping ^b   Ning, Beifang ^a   Zeng, Xin ^a   Lin, Yong ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGENASE 3; GELATINASE B; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA 21; MITOGEN ACTIVATED PROTEIN KINASE 1; S6 KINASE; SPROUTY PROTEIN; SPROUTY PROTEIN 2; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VIMENTIN; MICRORNA; MIRN21 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FEEDBACK SYSTEM; FEMALE; GENE TARGETING; HEPATITIS B; HEPATITIS C; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; LIVER CIRRHOSIS; LIVER FIBROSIS; MALE; NONHUMAN; PRIMARY BILIARY CIRRHOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL; ANIMAL; BLOOD; CELL LINE; GENETICS; LIVER; LIVER CELL; METABOLISM; MIDDLE AGED; PATHOLOGY; UPREGULATION;

ADULT; ANIMALS; CELL LINE; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HEPATOCYTES; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; MAP KINASE SIGNALING SYSTEM; MICRORNAS; MIDDLE AGED; RATS; UP-REGULATION;

EID: 84907853310     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108005     Document Type: Article

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