Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas

Oncogene

Volumn 30, Issue 21, 2011, Pages 2433-2442

  Kwak, H J ^a   Kim, Y J ^a,b   Chun, K R ^a   Woo, Y M ^a   Park, S J ^a   Jeong, J A ^a   Jo, S H ^a   Kim, T H ^a   Min, H S ^a   Chae, J S ^c   Choi, E J ^c   Kim, G ^a   Shin, S H ^a   Gwak, H S ^a   Kim, S K ^d   Hong, E K ^a   Lee, G K ^a   Choi, K H ^a   Kim, J H ^a   Yoo, H ^a   Park, J B ^a   Lee, S H ^a   more..

^a National Cancer Center   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Korea University   (South Korea)

^d Seoul National University Children's Hospital   (South Korea)

Author keywords

glioma; hyaluronan; invasion; miR 21; PTEN; spry2

Indexed keywords

GROWTH FACTOR; HYALURONIC ACID; MICRORNA 21; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN SPRY2; RAS PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTE; CANCER GRADING; CANCER GROWTH; CANCER INVASION; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR MICROENVIRONMENT; UPREGULATION; WILD TYPE;

BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HEK293 CELLS; HUMANS; HYALURONIC ACID; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICRORNAS; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RAS PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 79957611696     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.620     Document Type: Article

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