Ru(II)-catalyzed selective C-H amination of xanthones and chromones with sulfonyl azides: Synthesis and anticancer evaluation

Journal of Organic Chemistry

Volumn 79, Issue 19, 2014, Pages 9262-9271

  Shin, Youngmi ^a   Han, Sangil ^a   De, Umasankar ^a   Park, Jihye ^a   Sharma, Satyasheel ^a   Mishra, Neeraj Kumar ^a   Lee, Eui Kyung ^a   Lee, Youngil ^b   Kim, Hyung Sik ^a   Kim, In Su ^a  

^a Sungkyunkwan University   (South Korea)

^b University of Ulsan   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CATALYSIS; FUNCTIONAL GROUPS; KETONES;

ANTICANCER ACTIVITIES; C-H AMINATION; C-H BOND; CHROMONES; SULFONYL AZIDES;

RUTHENIUM ALLOYS;

2 FLUORO N (9 OXO 9H XANTHEN 1 YL)BENZENESULFONAMIDE; 3 CHLORO N (9 OXO 9H XANTHEN 1 YL)BENZENESULFONAMIDE; 4 BROMO N (9 OXO 9H XANTHEN 1 YL)BENZENESULFONAMIDE; 4 METHOXY N (9 OXO 9H XANTHEN 1 YL)BENZENESULFONAMIDE; 4 METHYL N (10 METHYL 9 OXO 9,10 DIHYDROACRIDIN 1 YL)BENZENESULFONAMIDE; 4 METHYL N (12 OXO 12H BENZO[A]XANTHEN 11 YL)BENZENESULFONAMIDE; 4 METHYL N (4 OXO 4H CHROMEN 5 YL)BENZENESULFONAMIDE; 4 METHYL N (4,6,7 TRIMETHYL 9 OXO 9H XANTHEN 1 YL)BENZENESULFONAMIDE; 4 METHYL N (7 METHYL 9 OXO 9H XANTHEN 1 YL)BENZENESULFONAMIDE; 4 METHYL N (9 OXO 9H THIOXANTHEN 1 YL)BENZENESULFONAMIDE; 4 METHYL N (9 OXO 9H XANTHEN 1 YL)BENZENESULFONAMIDE; 4 NITRO N (9 OXO 9H XANTHEN 1 YL)BENZENESULFONAMIDE; AZIDE; CHROMONE DERIVATIVE; CYTOTOXIC AGENT; DOXORUBICIN; N (2 FLUORO 9 OXO 9H XANTHEN 1 YL) 4 METHYLBENZENESULFONAMIDE; N (3 BROMO 4 OXO 4H CHROMEN 5 YL) 4 METHYLBENZENESULFONAMIDE; N (3 METHOXY 9 OXO 9H XANTHEN 1 YL) 4 METHYLBENZENESULFONAMIDE; N (6 METHOXY 9 OXO 9H XANTHEN 1 YL) 4 METHYLBENZENESULFONAMIDE; N (6,7 DIMETHYL 9 OXO 9H XANTHEN 1 YL) 4 METHYLBENZENESULFONAMIDE; N (7 GLUORO 9 OXO 9H XANTHEN 1 YL) 4 METHYLBENZENESULFONAMIDE; N (9 OXO 9H XANTHEN 1 YL) 4 (TRIFLUOROMETHYL)BENZENESULFONAMIDE; N (9 OXO 9H XANTHEN 1 YL)BENZENESULFONAMIDE; N (9 OXO 9H XANTHEN 1 YL)NAPHTHALENE 2 SULFONAMIDE; N (9,10 DIOXO 9,10 DIHYDROANTHRACEN 1 YL) 4 METHYLBENZENESULFONAMIDE; N [4 [N (9 OXO 9H XANTHEN 1 YL)SULFAMOYL]PHENYL]ACETAMIDE; RUTHENIUM; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHONE DERIVATIVE; ANTINEOPLASTIC AGENT; FLAVONOID;

AMIDATION; AMINATION; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER INHIBITION; CATALYSIS; CATALYST; CELL SURVIVAL; CELL VIABILITY; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; COVALENT BOND; CROSS COUPLING REACTION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROLYSIS; IC50; MCF 7 CELL LINE; CHEMISTRY; SYNTHESIS;

AMINATION; ANTINEOPLASTIC AGENTS; AZIDES; CATALYSIS; CHROMONES; FLAVONOIDS; MOLECULAR STRUCTURE; RUTHENIUM; XANTHONES;

EID: 84907778407     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo501709f     Document Type: Article

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