Synthesis and cytotoxic activity of 2-dialkylaminoethylamino substituted xanthenone and thioxanthenone derivatives

Farmaco

Volumn 55, Issue 6-7, 2000, Pages 455-460

  Kostakis, Ioannis ^a   Ghirtis, Konstantinos ^a   Pouli, Nicole ^a   Marakos, Panagiotis ^a   Skaltsounis, Alexios Leandros ^a   Leonce, Stephane ^b   Caignard, Daniel H ^b   Atassi, Ghanem ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

2 Dialkylaminoethylamino thioxanthenones; 2 Dialkylaminoethylamino xanthenones; Cell cycle selectivity; Cytotoxic activity

Indexed keywords

2,2 DIMETHYL 5 [[2 (1 PIPERIDINYL)ETHYL]AMINO] 2H,6H PYRANO[3,2 B]THIOXANTHEN 6 ONE; 2,2 DIMETHYL 5 [[2 (1 PIPERIDINYL)ETHYL]AMINO] 2H,6H PYRANO[3,2 B]XANTHEN 6 ONE; 2,2 DIMETHYL 5 [[2 (1 PYRROLIDINYL)ETHYL]AMINO] 2H,6H PYRANO[3,2 B]THIOXANTHEN 6 ONE; 2,2 DIMETHYL 5 [[2 (1 PYRROLIDINYL)ETHYL]AMINO] 2H,6H PYRANO[3,2 B]XANTHEN 6 ONE; 2,2 DIMETHYL 5 [[2 (DIETHYLAMINO)ETHYL]AMINO] 2H,6H PYRANO[3,2 B]THIOXANTHEN 6 ONE; 2,2 DIMETHYL 5 [[2 (DIETHYLAMINO)ETHYL]AMINO] 2H,6H PYRANO[3,2 B]XANTHEN 6 ONE; 2,2 DIMETHYL 5 [[2 (DIMETHYLAMINO)ETHYL]AMINO] 2H,6H PYRANO[3,2 B]THIOXANTHEN 6 ONE; 2,2 DIMETHYL 5 [[2 (DIMETHYLAMINO)ETHYL]AMINO] 2H,6H PYRANO[3,2 B]XANTHEN 6 ONE; 3,3 DIMETHYL 6 [[2 (1 PIPERIDINYL)ETHYL]AMINO] 3H,7H PYRANO[2,3 C]THIOXANTHEN 7 ONE; 3,3 DIMETHYL 6 [[2 (1 PIPERIDINYL)ETHYL]AMINO] 3H,7H PYRANO[2,3 C]XANTHEN 7 ONE; 3,3 DIMETHYL 6 [[2 (1 PYRROLIDINYL)ETHYL]AMINO] 3H,7H PYRANO[2,3 C]XANTHEN 7 ONE; 3,3 DIMETHYL 6 [[2 (1 PYRROLODINYL)ETHYL]AMINO] 3H,7H PYRANO[2,3 C]THIOXANTHEN 7 ONE; 3,3 DIMETHYL 6 [[2 (DIETHYLAMINO)ETHYL]AMINO] 3H,7H PYRANO[2,3 C]THIOXANTHEN 7 ONE; 3,3 DIMETHYL 6 [[2 (DIETHYLAMINO)ETHYL]AMINO] 3H,7H PYRANO[2,3 C]XANTHEN 7 ONE; 3,3 DIMETHYL 6 [[2 (DIMETHYLAMINO)ETHYL]AMINO] 3H,7H PYRANO[2,3 C]THIOXANTHEN 7 ONE; 3,3 DIMETHYL 6 [[2 (DIMETHYLAMINO)ETHYL]AMINO] 3H,7H PYRANO[2,3 C]XANTHEN 7 ONE; ACRONINE; ANTILEUKEMIC AGENT; CYTOTOXIC AGENT; HYCANTHONE; THIOXANTHENE DERIVATIVE; UNCLASSIFIED DRUG; XANTHENONE DERIVATIVE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE G2 PHASE; CELL SELECTION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SELECTIVITY; DRUG SYNTHESIS; LEUKEMIA CELL LINE; LEUKEMIA L 1210; MITOSIS INHIBITION; MOUSE; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; DRUG SCREENING ASSAYS, ANTITUMOR; FUMARATES; LEUKEMIA L1210; MICE; TUMOR CELLS, CULTURED; XANTHENES;

EID: 0033674279     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(00)00068-9     Document Type: Article

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