Synthesis of new xanthone analogues and their biological activity test-Cytotoxicity, topoisomerase II inhibition, and DNA cross-linking study

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 5, 2007, Pages 1163-1166

  Woo, Sangwook ^a   Jung, Ji ^b   Lee, Chongsoon ^c   Kwon, Youngjoo ^b   Na, Younghwa ^a  

^a Catholic University of Daegu   (South Korea)

^b Ewha Womans University   (South Korea)

^c Yeungnam University   (South Korea)

Author keywords

Anti cancer agents; DNA cross linking; Topoisomerase II inhibition; Xanthones

Indexed keywords

1,3 BIS(2',3' EPOXYPROPOXY)XANTHONE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; EPOXIDE; ETOPOSIDE; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; CYTOTOXICITY; DNA CROSS LINKING; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II; DRUG SCREENING ASSAYS, ANTITUMOR; EPOXY COMPOUNDS; HUMANS; INHIBITORY CONCENTRATION 50; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHONES;

EID: 33846898056     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.12.030     Document Type: Article

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