-
1
-
-
33746762852
-
Evolution of glucocorticoid receptors with different glucocorticoid sensitivity
-
Stolte EH, van Kemenade BM, Savelkoul HF, Flik G (2006) Evolution of glucocorticoid receptors with different glucocorticoid sensitivity. J Endocrinol 190: 17-28.
-
(2006)
J Endocrinol
, vol.190
, pp. 17-28
-
-
Stolte, E.H.1
Van Kemenade, B.M.2
Savelkoul, H.F.3
Flik, G.4
-
3
-
-
32144451932
-
Experimental studies on the significance of endotoxin in the pathogenesis of brucellosis
-
Spink WW, Anderson D (1954) Experimental studies on the significance of endotoxin in the pathogenesis of brucellosis. J Clin Invest 33: 540-548.
-
(1954)
J Clin Invest
, vol.33
, pp. 540-548
-
-
Spink, W.W.1
Anderson, D.2
-
4
-
-
26844433194
-
Antiinflammatory action of glucocorticoids-new mechanisms for old drugs
-
Rhen T, Cidlowski JA (2005) Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med 353: 1711-1723.
-
(2005)
N Engl J Med
, vol.353
, pp. 1711-1723
-
-
Rhen, T.1
Cidlowski, J.A.2
-
5
-
-
0036242607
-
Glucocorticoids: Do we know how they work?
-
Saklatvala J (2002) Glucocorticoids: do we know how they work? Arthritis Res 4: 146-150.
-
(2002)
Arthritis Res
, vol.4
, pp. 146-150
-
-
Saklatvala, J.1
-
6
-
-
84901626481
-
Abandon the mouse research ship?
-
Osuchowski MF, Remick DG, Lederer JA, Lang CH, Aasen AO, et al. (2014) Abandon the mouse research ship? Not just yet! Shock 41: 463-475.
-
(2014)
Not Just Yet! Shock
, vol.41
, pp. 463-475
-
-
Osuchowski, M.F.1
Remick, D.G.2
Lederer, J.A.3
Lang, C.H.4
Aasen, A.O.5
-
7
-
-
84874457770
-
Genomic responses in mouse models poorly mimic human inflammatory diseases
-
Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, et al. (2013) Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A 110: 3507-3512.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 3507-3512
-
-
Seok, J.1
Warren, H.S.2
Cuenca, A.G.3
Mindrinos, M.N.4
Baker, H.V.5
-
9
-
-
79958773563
-
Knockout of the vascular endothelial glucocorticoid receptor abrogates dexamethasone-induced hypertension
-
Goodwin JE, Zhang J, Gonzalez D, Albinsson S, Geller DS (2011) Knockout of the vascular endothelial glucocorticoid receptor abrogates dexamethasone-induced hypertension. J Hypertens 29: 1347-1356.
-
(2011)
J Hypertens
, vol.29
, pp. 1347-1356
-
-
Goodwin, J.E.1
Zhang, J.2
Gonzalez, D.3
Albinsson, S.4
Geller, D.S.5
-
10
-
-
84871981752
-
Endothelial glucocorticoid receptor is required for protection against sepsis
-
Goodwin JE, Feng Y, Velazquez H, Sessa WC (2013) Endothelial glucocorticoid receptor is required for protection against sepsis. Proc Natl Acad Sci U S A 110: 306-311.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 306-311
-
-
Goodwin, J.E.1
Feng, Y.2
Velazquez, H.3
Sessa, W.C.4
-
11
-
-
79951634603
-
Control of lipopolysaccharide biosynthesis by FtsH-mediated proteolysis of LpxC is conserved in enterobacteria but not in all gram-negative bacteria
-
Langklotz S, Schakermann M, Narberhaus F (2011) Control of lipopolysaccharide biosynthesis by FtsH-mediated proteolysis of LpxC is conserved in enterobacteria but not in all gram-negative bacteria. J Bacteriol 193: 1090-1097.
-
(2011)
J Bacteriol
, vol.193
, pp. 1090-1097
-
-
Langklotz, S.1
Schakermann, M.2
Narberhaus, F.3
-
12
-
-
0037390942
-
Protection against lipopolysaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice
-
Chauhan SD, Seggara G, Vo PA, Macallister RJ, Hobbs AJ, et al. (2003) Protection against lipopolysaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice. FASEB J 17: 773-775.
-
(2003)
FASEB J
, vol.17
, pp. 773-775
-
-
Chauhan, S.D.1
Seggara, G.2
Vo, P.A.3
Macallister, R.J.4
Hobbs, A.J.5
-
13
-
-
0032416121
-
Protective roles of nitric oxide and testosterone in endotoxemia: Evidence from NOS-2-deficient mice
-
Laubach VE, Foley PL, Shockey KS, Tribble CG, Kron IL (1998) Protective roles of nitric oxide and testosterone in endotoxemia: evidence from NOS-2-deficient mice. Am J Physiol 275: H2211-2218.
-
(1998)
Am J Physiol
, vol.275
, pp. H2211-2218
-
-
Laubach, V.E.1
Foley, P.L.2
Shockey, K.S.3
Tribble, C.G.4
Kron, I.L.5
-
14
-
-
36448943901
-
Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease
-
Fernandez-Hernando C, Ackah E, Yu J, Suarez Y, Murata T, et al. (2007) Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. Cell Metab 6: 446-457.
-
(2007)
Cell Metab
, vol.6
, pp. 446-457
-
-
Fernandez-Hernando, C.1
Ackah, E.2
Yu, J.3
Suarez, Y.4
Murata, T.5
-
15
-
-
77956107516
-
Discovery of glucocorticoid receptor-beta in mice with a role in metabolism
-
Hinds TD Jr, Ramakrishnan S, Cash HA, Stechschulte LA, Heinrich G, et al. (2010) Discovery of glucocorticoid receptor-beta in mice with a role in metabolism. Mol Endocrinol 24: 1715-1727.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 1715-1727
-
-
Hinds, T.D.1
Ramakrishnan, S.2
Cash, H.A.3
Stechschulte, L.A.4
Heinrich, G.5
-
16
-
-
0018146287
-
Dexamethasone antagonism of glucose dyshomeostasis in endotoxin shock
-
Figlewicz DP, Filkins JP (1978) Dexamethasone antagonism of glucose dyshomeostasis in endotoxin shock. Circ Shock 5: 317-323.
-
(1978)
Circ Shock
, vol.5
, pp. 317-323
-
-
Figlewicz, D.P.1
Filkins, J.P.2
-
17
-
-
0030031089
-
Tissue expression of endothelin-1 mRNA in endotoxaemia
-
Kaddoura S, Curzen NP, Evans TW, Firth JD, Poole-Wilson PA (1996) Tissue expression of endothelin-1 mRNA in endotoxaemia. Biochem Biophys Res Commun 218: 641-647.
-
(1996)
Biochem Biophys Res Commun
, vol.218
, pp. 641-647
-
-
Kaddoura, S.1
Curzen, N.P.2
Evans, T.W.3
Firth, J.D.4
Poole-Wilson, P.A.5
-
18
-
-
54949096502
-
The role of MAP kinase phosphatase-1 in the protective mechanism of dexamethasone against endotoxemia
-
Wang X, Nelin LD, Kuhlman JR, Meng X, Welty SE, et al. (2008) The role of MAP kinase phosphatase-1 in the protective mechanism of dexamethasone against endotoxemia. Life Sci 83: 671-680.
-
(2008)
Life Sci
, vol.83
, pp. 671-680
-
-
Wang, X.1
Nelin, L.D.2
Kuhlman, J.R.3
Meng, X.4
Welty, S.E.5
-
19
-
-
0031757934
-
Nuclear factor kappa B: Important transcription factor and therapeutic target
-
Lee JI, Burckart GJ (1998) Nuclear factor kappa B: important transcription factor and therapeutic target. J Clin Pharmacol 38: 981-993.
-
(1998)
J Clin Pharmacol
, vol.38
, pp. 981-993
-
-
Lee, J.I.1
Burckart, G.J.2
-
20
-
-
84875266862
-
Lipopolysaccharide-induced inhibition of transcription of tlr4 in vitro is reversed by dexamethasone and correlates with presence of conserved NFkappaB binding sites
-
Bonin CP, Baccarin RY, Nostell K, Nahum LA, Fossum C, et al. (2013) Lipopolysaccharide-induced inhibition of transcription of tlr4 in vitro is reversed by dexamethasone and correlates with presence of conserved NFkappaB binding sites. Biochem Biophys Res Commun 432: 256-261.
-
(2013)
Biochem Biophys Res Commun
, vol.432
, pp. 256-261
-
-
Bonin, C.P.1
Baccarin, R.Y.2
Nostell, K.3
Nahum, L.A.4
Fossum, C.5
-
21
-
-
84878818465
-
Septic serum induces glucocorticoid resistance and modifies the expression of glucocorticoid isoforms receptors: A prospective cohort study and in vitro experimental assay
-
Guerrero J, Gatica HA, Rodriguez M, Estay R, Goecke IA (2013) Septic serum induces glucocorticoid resistance and modifies the expression of glucocorticoid isoforms receptors: a prospective cohort study and in vitro experimental assay. Crit Care 17: R107.
-
(2013)
Crit Care
, vol.17
, pp. R107
-
-
Guerrero, J.1
Gatica, H.A.2
Rodriguez, M.3
Estay, R.4
Goecke, I.A.5
-
22
-
-
77954602478
-
Glucocorticoid receptor-beta and receptor-gamma exert dominant negative effect on gene repression but not on gene induction
-
Taniguchi Y, Iwasaki Y, Tsugita M, Nishiyama M, Taguchi T, et al. (2010) Glucocorticoid receptor-beta and receptor-gamma exert dominant negative effect on gene repression but not on gene induction. Endocrinology 151: 3204-3213.
-
(2010)
Endocrinology
, vol.151
, pp. 3204-3213
-
-
Taniguchi, Y.1
Iwasaki, Y.2
Tsugita, M.3
Nishiyama, M.4
Taguchi, T.5
-
23
-
-
0029993518
-
The human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative function
-
Oakley RH, Sar M, Cidlowski JA (1996) The human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative function. J Biol Chem 271: 9550-9559.
-
(1996)
J Biol Chem
, vol.271
, pp. 9550-9559
-
-
Oakley, R.H.1
Sar, M.2
Cidlowski, J.A.3
-
24
-
-
0035810930
-
Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: A mechanism for the generation of glucocorticoid resistance
-
Webster JC, Oakley RH, Jewell CM, Cidlowski JA (2001) Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: a mechanism for the generation of glucocorticoid resistance. Proc Natl Acad Sci U S A 98: 6865-6870.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6865-6870
-
-
Webster, J.C.1
Oakley, R.H.2
Jewell, C.M.3
Cidlowski, J.A.4
-
25
-
-
0030774245
-
Expression and subcellular distribution of the beta-isoform of the human glucocorticoid receptor
-
Oakley RH, Webster JC, Sar M, Parker CR Jr, Cidlowski JA (1997) Expression and subcellular distribution of the beta-isoform of the human glucocorticoid receptor. Endocrinology 138: 5028-5038.
-
(1997)
Endocrinology
, vol.138
, pp. 5028-5038
-
-
Oakley, R.H.1
Webster, J.C.2
Sar, M.3
Parker, C.R.4
Cidlowski, J.A.5
-
26
-
-
84907746150
-
Resistance of LPS-activated bone marrow derived macrophages to apoptosis mediated by dexamethasone
-
Haim YO, Unger ND, Souroujon MC, Mittelman M, Neumann D (2014) Resistance of LPS-activated bone marrow derived macrophages to apoptosis mediated by dexamethasone. Sci Rep 4: 4323.
-
(2014)
Sci Rep
, vol.4
, pp. 4323
-
-
Haim, Y.O.1
Unger, N.D.2
Souroujon, M.C.3
Mittelman, M.4
Neumann, D.5
-
27
-
-
84861716717
-
Crosstalk between NFkB and glucocorticoid signaling: A potential target of breast cancer therapy
-
Ling J, Kumar R (2012) Crosstalk between NFkB and glucocorticoid signaling: a potential target of breast cancer therapy. Cancer Lett 322: 119-126.
-
(2012)
Cancer Lett
, vol.322
, pp. 119-126
-
-
Ling, J.1
Kumar, R.2
-
28
-
-
84877111118
-
Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation
-
Sorrells SF, Caso JR, Munhoz CD, Hu CK, Tran KV, et al. (2013) Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation. J Neurosci 33: 7877-7889.
-
(2013)
J Neurosci
, vol.33
, pp. 7877-7889
-
-
Sorrells, S.F.1
Caso, J.R.2
Munhoz, C.D.3
Hu, C.K.4
Tran, K.V.5
-
29
-
-
84883357296
-
Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle
-
Gupte R, Muse GW, Chinenov Y, Adelman K, Rogatsky I (2013) Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle. Proc Natl Acad Sci U S A 110: 14616-14621.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 14616-14621
-
-
Gupte, R.1
Muse, G.W.2
Chinenov, Y.3
Adelman, K.4
Rogatsky, I.5
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