Evolution of glucocorticoid receptors with different glucocorticoid sensitivity

Journal of Endocrinology

Volumn 190, Issue 1, 2006, Pages 17-28

  Stolte, Ellen H ^a,b   Verburg van Kemenade, B M Lidy ^b   Savelkoul, Huub F J ^b   Flik, Gert ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; DNA; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HYDROCORTISONE; RNA;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; CORTICOTROPIN RELEASE; DNA BINDING; DRUG EFFICACY; DRUG RESISTANCE; EXON; EXPERIMENTAL MODEL; FISH; GENE EXPRESSION; GENE INSERTION; GENETIC ANALYSIS; GENETIC CODE; GENETIC CONSERVATION; GENETIC VARIABILITY; HUMAN; IMMUNE SYSTEM; IN VIVO STUDY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR SENSITIVITY; REGULATORY MECHANISM; REVIEW; SEQUENCE ANALYSIS; STRESS; TELEOST; TRANSACTIVATION; VERTEBRATE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; EVOLUTION, MOLECULAR; FISHES; GLUCOCORTICOIDS; HUMANS; IMMUNE SYSTEM; MOLECULAR SEQUENCE DATA; RECEPTORS, GLUCOCORTICOID; SEQUENCE HOMOLOGY; SPECIES SPECIFICITY; STRESS;

EID: 33746762852     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.1.06703     Document Type: Review

References (72)

1. Boers M 2004 Glucocorticoids in rheumatoid arthritis: a senescent research agenda on the brink of rejuvenation? Best Practice and Research Clinical Rheumatology 18 21-29.
2. Brandon DD, Markwick AJ, Flores M, Dixon K, Albertson BD & Loriaux DL 1991 Genetic variation of the glucocorricoid receptor from a steroid-resistant primate. Journal of Molecular Endocrinology 7 89-96.
3. Bray PJ & Cotton RG 2003 Variations of the human glucocorticoid receptor gene (NR3C1): pathological and in vitro mutations and polymorphisms. Human Mutation 21 557-568.
4. Bury NR, Sturm A, Le Rouzic P, Lethimonier C, Ducouret B, Guiguen Y, Robinson-Rechavi M, Laudet V, Rafestin-Oblin ME & Prunet P 2003 Evidence for two distinct functional glucocorticoid receptors in teleost fish. Journal of Molecular Endocrinology 31 141-156.
5. Charmandari E, Tsigos C & Chrousos G 2005 Endocrinology of the stress response. Annual Review of Physiology 67 259-284.
6. Dean DB, Whitlow ZW & Borski PJ 2003 Glucocorticoid receptor upregulation during seawater adaptation in a euryhaline teleost, the tilapia (Oreochromis mossambicus). General and Comparative Endocrinology 132 112-118.
7. DeRijk RH, Schaaf M & de Kloet ER 2002 Glucocorticoid receptor variants: clinical implications. Journal of Steroid Biochemistry and Molecular Biology 81 103-122.
8. Dhabhar FS, Miller AH, McEwen BS & Spencer RL 1996 Stress-induced changes in blood leukocyte distribution, Role of adrenal steroid hormones. Journal of Immunology 157 1638-1644.
9. Ducouret B, Tujague M, Ashraf J, Mouchel N, Servel N, Valotaire Y & Thompson EB 1995 Cloning of a teleost fish glucocorticoid receptor shows that it contains a deoxyribonucleic acid-binding domain different from that of mammals. Endocrinology 136 3774-3783.
10. Elenkov IJ 2004 Glucocorticoids and the Th1/Th2 balance. Annals of the New York Academy of Sciences 1024 138-146.
11. Evans RM 2005 The nuclear receptor superfamily: a rosetta stone for physiology. Molecular Endocrinology 19 1429-1438.
12. Franchimont D 2004 Overview of the actions of glucocorticoids on the immune response: a good model to characterize new pathways of immumosuppression for new treatment strategies. Annals of the New York Academy of Sciences 1024 124-137.
13. Fuller PJ 1991 The steroid receptor superfamily: mechanisms of diversity FASEB Journal 5 3092-3099.
14. Geng CD, Pedersen KB, Nunez BS & Vedeckis WV 2005 Human glucocorticoid receptor alpha transcript splice variants with exon 2 deletions: evidence for tissue- and cell type-specific functions. Biochemistry 44 7395-7405.
15. Giannoukos G, Silverstein AM, Pratt WB & Simons SS Jr. 1999 The seven amino acids (547-553) of rat glucocorticoid receptor required for steroid and hsp90 binding contain a functionally independent LXXLL motif that is critical for steroid binding. Journal of Biological Chemistry 274 36527-36536.
16. Giguere V, Hollenberg SM, Rosenfeld MG & Evans RM 1986 Functional domains of the human glucocorticoid receptor. Cell 46 645-652.
17. Greenwood AK, Butler PC, White RB, DeMarco U, Pearce D & Fernald RD 2003 Multiple corticosteroid receptors in a teleost fish: distinct sequences, expression patterns, and transcriptional activities. Endocrinology 144 4226-4236.
18. Hard T, Kellenbach E, Boelens R, Maler BA, Dahlman K, Freedman LP, Carlstedt-Duke J, Yamamoto KR, Gustafsson JA & Kaptein R 1990 Solution structure of the glucocorticoid receptor DNA-binding domain (in Reports). Science 249 157-160.
19. Hearing SD, Norman M, Smyth C, Foy C & Dayan CM 1999 Wide variation in lymphocyte steroid sensitivity among healthy human volunteers. Journal of Clinical Endocrinology and Metabolism 84 4149-4154.
20. Hedges SB & Kumar S 2002 Genomics, Vertebrate genomes compared. Science 297 1283-1285.
21. Hennessy MB, Davis HN, Williams MT, Mellott C & Douglas CW 1997 Plasma cortisol levels of dogs at a county animal shelter. Physiology and Behavior 62 485-490.
22. Hoegg S, Brinkmann H, Taylor JS & Meyer A 2004 Phylogenetic timing of the fish-specific genome duplication correlates with the diversification of teleost fish. Journal of Molecular Evolution 59 190-203.
23. Hollenberg SM, Weinberger C, Ong ES, Cerelli G, Oro A, Lebo R, Thompson EB, Rosenfeld MG & Evans RM 1985 Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature 318 635-641.
24. Huising MO, Guichelaar T, Hoek C, Verburg-van Kemenade BM, Flik G, Savelkoul HF & Rombout JH 2003 Increased efficacy of immersion vaccination in fish with hyperosmotic pretreatment. Vaccine 21 4178-4193.
25. Ismaili N & Garabedian MJ 2004 Modulation of glucocorticoid receptor function via phosphorylation. Annals of the New York Academy of Sciences 1024 86-101.
26. Kanelakis KC, Shewach DS & Pratt WB 2002 Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly. Journal of Biological Chemistry 277 33698-33703.
27. Keightley MC & Fuller PJ 1994 Unique sequences in the guinea pig glucocorticoid receptor induce constitutive transactivation and decrease steroid sensitivity. Molecular Endocrinology 8 431-439.
28. Keightley MC, Curtis AJ, Chu S & Fuller PJ 1998 Structural determinants of cortisol resistance in the guinea pig glucocorticoid receptor. Endocrinology 139 2479-2485.
29. Knoebl I, Fitzpatrick MS & Schreck CB 1996 Characterization of a glucocorticoid receptor in the brains of chinook salmon, Oncorhynchus tshawytscha. General and Comparative Endocrinology 101 195-204.
30. Kraft N, Hodgson AJ & Funder JW 1979 Glucocorticoid receptor and effector mechanisms: a comparison of the corticosensitive mouse with the corticoresistant guinea pig. Endocrinology 104 344-349.
31. Kumar R & Thompson EB 1999 The structure of the nuclear hormone receptors. Steroids 64 310-319.
32. Kumar R & Thompson EB 2005 Gene regulation by the glucocorticoid receptor: structure:function relationship. Journal of Steroid Biochemistry and Molecular Biology 94 383-394.
33. Kumar S, Tamura K & Nei M 2004 MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment. Briefings in Bioinformatics 5 150-163.
34. Lamberts SW, Huizenga AT, de Lange P, de Jong FH & Koper JW 1996 Clinical aspects of glucocorticoid sensitivity. Steroids 61 157-160.
35. Lethimonier C, Tujague M, Kern L & Ducouret B 2002 Peptide insertion in the DNA-binding domain of fish glucocorticoid receptor is encoded by an additional exon and confers particular functional properties. Molecular and Cellular Endocrinology 194 107-116.
36. Luisi BF, Xu WX, Otwinowski Z, Freedman LP, Yamamoto KR & Sigler PB 1991 Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature 352 497-505.
37. Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, Schutz G, Umesono K, Blumberg B, Kastner P, Mark M et al. 1995 The nuclear receptor superfamily: the second decade. Cell 83 835-839.
38. Maule AG & Schreck CB 1990 Glucocorticoid receptors in leukocytes and gill of juvenile coho salmon (Oncorhynchus kisutch). General and Comparative Endocrinology 77 448-455.
39. Metz JR, van den Burg EH, Bonga SE & Flik G 2003 Regulation of branchial Na(+)/K(+)-ATPase in common carp Cyprinus carpio L. acclimated to different temperatures. Journal of Experimental Biology 206 2273-2280.
40. Morishima Y, Kanelakis KC, Silverstein AM, Dittmar KD, Estrada L & Pratt WB 2000a The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system. Journal of Biological Chemistry 275 6894-6900.
41. Morishima Y, Murphy PJ, Li DP, Sanchez ER & Pratt WB 2000b Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket. Journal of Biological Chemistry 275 18054-18060.
42. Nelson JS. 1994. Fishes of the world. New York, NY, USA: John Wiley & Sons Inc.
43. Oakley RH, Jewell CM, Yudt MR, Bofetiado DM & Cidlowski JA 1999 The dominant negative activity of the human glucocorticoid receptor beta isoform, Specificity and mechanisms of action. Journal of Biological Chemistry 274 27857-27866.
44. Piekarzewska AB, Rosochacki SJ & Sender G 2000 The effect of acute restraint stress on regional brain neurotransmitter levels in stress-susceptible pietrain pigs. Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine 47 257-269.
45. Pratt WB & Toft DO 1997 Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocrine Reviews 18 306-360.
46. Pratt WB & Toft DO 2003 Regulation of signaling protein function and trafficking by the hsp90/hsp7O-based chaperone machinery. Experimental Biology and Medicine (Maywood) 228 111-133.
47. Ray DW, Davis JR, White A & Clark AJ 1996 Glucocorticoid receptor structure and function in glucocorticoid-resistant small cell lung carcinoma cells. Cancer Research 56 3276-3280.
48. Ray DW, Suen CS, Brass A, Soden J & White A 1999 Structure/function of the human glucocorticoid receptor: tyrosine 735 is important for transactivation. Molecular Endocrinology 13 1855-1863.
49. Rivers C, Levy A, Hancock J, Lightman S & Norman M 1999 Insertion of an amino acid in the DNA-binding domain ofthe glucocorticoid receptor as a result of alternative splicing. Journal of Clinical Endocrinology and Metabolism 84 4283-4286.
50. Saitou N & Nei M 1987 The neighbor-joining method: a new method for reconstructing phylogenetic trees. Molecular Biology and Evolution 4 406-425.
51. Sapolsky RM, Romero LM & Munck AU 2000 How do glucocorticoids influence stress responses?, Integrating perritissive, suppressive, stimulatory, and preparative actions. Endocrine Reviews 21 55-89.
52. Schoneveld OJ, Gaemers IC & Lamers WH 2004 Mechanisms of glutcocorticoid signalling. Biochimica et Biophysica Acta 1680 114-128.
53. Stevens A, Donn R & Ray D 2004a Regulation of glucocorticoid receptor gamma (GRgamma) by glucocorticoid receptor haplotype and glucocorticoid. Clinical Endocrinology 61 327-331.
54. Stevens A, Ray DW, Zeggini E, John S, Richards HL, Griffiths CE & Donn R 2004b Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype. Journal of Clinical Endocrinology and Metabolism 89 892-897.
55. Sturm A & Bury NR 2005 Duplicate teleost glucocorticoid receptors are not functionally redundant: relationship between structural and functional differences. Comparative Biochemistry and Physiology 141A S208.
56. Sturm A, Bury N, Dengreville L, Fagart J, Flouriot G, Rafestin-Oblin ME & Prunet P 2004 11 -deoxycorticosterone is a potent agonist of the rainbow trout (Oncorhynchus mykiss) mineralocorticoid receptor. Endocrinology 146 47-55.
57. Takeo J, Hata J, Segawa C, Toyohara H & Yamashita S 1996 Fish glucocorticoid receptor with splicing variants in the DNA binding domain. FEBS Letters 389 244-248.
58. Thornton JW 2001 Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions. PNAS 98 5671-5676.
59. Todo T & Nagahama 1998 Structure and function of fish steroid hormone receptors. Kaiyo Monthly 30 96-102.
60. Tokuda Y, Touhata K, Kinoshita M, Toyohara H, Sakaguchi M, Yokoyame Y, Ichikawa T & Yamashita S 1999 Sequence and expression of a cDNA encoding Japanese flounder glucocorticoid receptor. Fisheries Science 65 466-471.
61. Umesono K & Evans RM 1989 Determinants of target gene specificity for steroid/thyroid hormone receptors. Cell 57 1139-1146.
62. Van Cauter E, Leproult R & Kupfer DJ 1996 Effects of gender and age on the levels and circadian rhythmicity of plasma cortisol. Journal of Clinical Endocrinology and Metabolism 81 2468-2473.
63. van Rossum EF, Koper JW, Huizenga NA, Uitterlinden AG, Janssen JA, Brinkmann AO, Grobbee DE, de Jong FH, van Duyn CM, Pols HA et al. 2002 A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels. Diabetes 51 3128-3134.
64. Volff JN 2005 Genome evolution and biodiversity in teleost fish. Heredity 94 280-294.
65. Walsh GM 2005 Novel therapies for asthma - advances and problems. Current Pharmaceutical Design 11 3027-3038.
66. Wang Q & Fondell JD 2001 Generation of a mammalian cell line stably expressing a tetracyclin-regulated epitope-tagged human androgen receptor: implications for steroid hormone receptor research. Analytical Biochemistry 289 217-230.
67. Webster JC, Jewell CM, Bodwell JE, Munck A, Sar M & Cidlowski JA 1997 Mouse glutcocorticoid receptor phosphorylation status influences multiple functions of the receptor protein. Journal of Biological Chemistry 272 9287-9293.
68. Wendelaar Bonga SE 1997 The stress response in fish. Physiological Reviews 77 591-625.
69. Weyts FA, Flik G, Rombout JH & Verburg-van Kemenade BM 1998a Cortisol induces apoptosis in activated B cells, not in other lymphoid cells of the common carp, Cyprinus carpic, L. Developmental and Comparative Immunology 22 551-562.
70. Weyts FA, Flik G & Verburg-van Kemenade BM 1998b Cortisol inhibits apoptosis in carp neutrophilic granulocytes. Developmental and Comparative Immunology 22 563-572.
71. Weyrs FA, Verburg-van Kemenade BM & Flik G 1998c Characterisation of glucocorticoid receptors in peripheral blood leukocytes of carp, Cyprinus carpio L. General and Comparative Endocrinology 111 1-8.
72. Wickert L & Selbig J 2002 Structural analysis of the DNA-binding domain of alternatively spliced steroid receptors. Journal of Endocrinology 173 429-436.